المؤلفون: Qadri, Sami, Lallukka-Brück, Susanna, Luukkonen, Panu K., Zhou, You, Gastaldelli, Amalia, Orho-Melander, Marju, Sammalkorpi, Henna, Juuti, Anne, Penttilä, Anne K., Perttilä, Julia, Hakkarainen, Antti, Lehtimäki, Tiina E., Oresic, Matej, 1967, Hyötyläinen, Tuulia, 1971, Hodson, Leanne, Olkkonen, Vesa M., Yki-Järvinen, Hannele

المصدر: Liver international (Print). 40(9):2128-2138

مصطلحات موضوعية: Adipose tissue, fatty acids, lipidomics, lipolysis, non-alcoholic fatty liver disease, triglycerides

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-81765Test
https://doi.org/10.1111/liv.14507Test

المؤلفون: Toppila, Iiro, Ukkola‐Vuoti, Liisa, Perttilä, Julia, Törnwall, Outi, Sinisalo, Juha, Hartikainen, Juha, Lehto, Seppo

المصدر: Clinical Cardiology ; volume 45, issue 4, page 342-351 ; ISSN 0160-9289 1932-8737

الإتاحة: https://doi.org/10.1002/clc.23814Test

المؤلفون: Qadri, Sami, Lallukka-Brück, Susanna, Luukkonen, Panu K., Zhou, You, Gastaldelli, Amalia, Orho-Melander, Marju, Sammalkorpi, Henna, Juuti, Anne, Penttilä, Anne K., Perttilä, Julia, Hakkarainen, Antti, Lehtimäki, Tiina E., Oresic, Matej, Hyötyläinen , Tuulia, Hodson, Leanne, Olkkonen, Vesa M., Yki-Järvinen, Hannele

المساهمون: Department of Medicine, Clinicum, Doctoral Programme in Clinical Research, HUS Internal Medicine and Rehabilitation, University of Helsinki, Helsinki University Hospital Area, HUS Abdominal Center, Department of Surgery, HUS Medical Imaging Center, Department of Diagnostics and Therapeutics, Hannele Yki-Järvinen Research Group

مصطلحات موضوعية: adipose tissue, fatty acids, lipidomics, lipolysis, non-alcoholic fatty liver disease, triglycerides, fatty liver disease, variant, mutation, INSULIN RESISTANCE, genetics, ADIPONUTRIN, OBESITY, STEATOSIS, fatty liver, PNPLA3, NAFLD, rasvakudos, ihonalaisrasva, rasvahapot, lipidomiikka, lipolyysi, ei-alkoholiperäinen rasvamaksatauti, triglyseridit, rasvamaksatauti, rasvamaksa, genetiikka, mutaatio, variantti, insuliiniresistenssi

وصف الملف: application/pdf

العلاقة: Novo Nordisk Foundation; EU H2020-JTI-IMI2 project 777377-2 Liver Investigation: Testing Marker Utility in Steatohepatitis; British Heart Foundation, Grant/Award Number: FS/15/56/31645; EU H2020 project ` Elucidating Pathways of Steatohepatitis', Grant/Award Number: 634413; Sigrid Juselius Foundation; EVO; Academy of Finland, Grant/Award Number: 309263; Qadri , S , Lallukka-Brück , S , Luukkonen , P K , Zhou , Y , Gastaldelli , A , Orho-Melander , M , Sammalkorpi , H , Juuti , A , Penttilä , A K , Perttilä , J , Hakkarainen , A , Lehtimäki , T E , Oresic , M , Hyötyläinen , T , Hodson , L , Olkkonen , V M & Yki-Järvinen , H 2020 , ' The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue ' , Liver International , vol. 40 , no. 9 , pp. 2128-2138 . https://doi.org/10.1111/liv.14507Test; ORCID: /0000-0001-9313-9324/work/125979359; http://hdl.handle.net/10138/333732Test; d75894be-4c6c-4c80-aba7-295bc9a45e3a; 000533393400001

الإتاحة: http://hdl.handle.net/10138/333732Test

المؤلفون: Lassenius, Mariann I, Toppila, Iiro, Bergius, Susanne, Perttilä, Julia, Airaksinen, K E Juhani, Pietilä, Mikko

المصدر: European Journal of Preventive Cardiology ; volume 28, issue 8, page 884-892 ; ISSN 2047-4873 2047-4881

الإتاحة: https://doi.org/10.1177/2047487320904334Test
http://academic.oup.com/eurjpc/article-pdf/28/8/884/39301689/zwaa244.pdfTest

المؤلفون: Ruuth, Maija, Soronen, Jarkko, Kaiharju, Essi, Merikanto, Krista, Perttilä, Julia, Metso, Jari, Lee-Rueckert, Miriam, Taskinen, Marja-Riitta, Kovanen, Petri T., Öörni, Katariina, Olkkonen, Vesa M., Jauhiainen, Matti S., Laurila, Pirkka-Pekka

المساهمون: Medicum, Research Programs Unit, University of Helsinki, Clinicum, Diabetes and Obesity Research Program, Marja-Riitta Taskinen Research Group, Department of Anatomy, Department of Medical and Clinical Genetics, Institute for Molecular Medicine Finland, HUS Internal Medicine and Rehabilitation, HUS Heart and Lung Center

مصطلحات موضوعية: USF1, High density lipoproteins, Cholesterol efflux, Cholesterol accumulation, Macrophage, Hepatocyte, Inflammation, FAMILIAL COMBINED HYPERLIPIDEMIA, UPSTREAM TRANSCRIPTION FACTOR-1, HIGH-DENSITY-LIPOPROTEINS, LYSOSOMAL ACID LIPASE, ESTER HYDROLASE 1, FOAM CELLS, HIGH-RISK, ATHEROSCLEROSIS, ASSOCIATION, CAPACITY, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: This study was supported by the Finnish Foundation for Cardiovascular Research (MJ, VMO, PPL, JS), Jenny and Antti Wihuri Foundation (MJ, JS), Novo-Nordisk Foundation (MRT, VMO), Paavo Nurmi Foundation (MJ, PPL, JS, VMO), Academy of Finland (Grant #257545 to MJ and #265940 to KO), Finska Lakaresallskapet (PPL), Aarne Koskelo Foundation (PPL), Emil Aaltonen Foundation (PPL), Foundation for Diabetes Research (PPL, JS), Magnus Ehrnrooth Foundation (PPL, VMO), Jane and Aatos Erkko Foundation (MJ), Sigrid Juselius Foundation (PPL, VMO) and The Finnish Medical Foundation (PPL). Wihuri Research Institute (MR, MLR, KO, PTK) is maintained by the Jenny and Antti Wihuri Foundation.; Ruuth , M , Soronen , J , Kaiharju , E , Merikanto , K , Perttilä , J , Metso , J , Lee-Rueckert , M , Taskinen , M-R , Kovanen , P T , Öörni , K , Olkkonen , V M , Jauhiainen , M S & Laurila , P-P 2018 , ' USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages ' , Lipids in Health and Disease , vol. 17 , 285 . https://doi.org/10.1186/s12944-018-0930-2Test; ORCID: /0000-0001-8903-0617/work/52400340; ORCID: /0000-0002-6229-3588/work/90756889; 85058544449; de8fd278-34aa-46f9-8fe9-18202e39e9cb; http://hdl.handle.net/10138/287689Test; 000453307200005

الإتاحة: http://hdl.handle.net/10138/287689Test

المؤلفون: Soronen, Jarkko, Yki-Järvinen, Hannele, Zhou, You, Sädevirta, Sanja, Sarin, Antti-Pekka, Leivonen, Marja, Sevastianova, Ksenia, Perttilä, Julia, Laurila, Pirkka-Pekka, Sigruener, Alexander, Schmitz, Gerd, Olkkonen, Vesa M.

المساهمون: Department of Medicine, Clinicum, Institute for Molecular Medicine Finland, II kirurgian klinikka, Medicum, Department of Anatomy

مصطلحات موضوعية: Hepatocyte, immortalized human hepatocytes, liver biopsy, microarray, microRNA, nonalcoholic fatty liver disease, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: Soronen , J , Yki-Järvinen , H , Zhou , Y , Sädevirta , S , Sarin , A-P , Leivonen , M , Sevastianova , K , Perttilä , J , Laurila , P-P , Sigruener , A , Schmitz , G & Olkkonen , V M 2016 , ' Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease ' , Physiological Reports , vol. 4 , no. 1 , e12661 . https://doi.org/10.14814/phy2.12661Test; Bibtex: urn:e704d5c963b9710fbf63f9ae573b8b2d; 84987648111; 97a6fd8e-6f89-44be-b2af-c253b76f6088; http://hdl.handle.net/10138/231593Test; 000380233800004

الإتاحة: http://hdl.handle.net/10138/231593Test

المؤلفون: Ruuth, Maija, Soronen, Jarkko, Kaiharju, Essi, Merikanto, Krista, Perttilä, Julia, Metso, Jari, Lee-Rueckert, Miriam, Taskinen, Marja-Riitta, Kovanen, Petri T., Öörni, Katariina, Olkkonen, Vesa M., Jauhiainen, Matti S., Laurila, Pirkka-Pekka

المساهمون: Sydäntutkimussäätiö, Academy of Finland, Novo Nordisk Foundation, Jenny ja Antti Wihurin Rahasto, Paavo Nurmen Säätiö, Finska Läkaresällskapet, Aarne Koskelon Säätiö, Emil Aaltosen Säätiö, Foundation for Diabetes Research, Magnus Ehrnroothin Säätiö, Jane ja Aatos Erkon Säätiö, Sigrid Juséliuksen Säätiö, Suomen Lääketieteen Säätiö

المصدر: Lipids in Health and Disease ; volume 17, issue 1 ; ISSN 1476-511X

مصطلحات موضوعية: Biochemistry (medical), Clinical Biochemistry, Endocrinology, Endocrinology, Diabetes and Metabolism

الإتاحة: https://doi.org/10.1186/s12944-018-0930-2Test

المؤلفون: Soronen, Jarkko, Yki-Järvinen, Hannele, Zhou, You, Sädevirta, Sanja, Sarin, Antti-Pekka, Leivonen, Marja, Sevastianova, Ksenia, Perttilä, Julia, Laurila, Pirkka-Pekka, Sigruener, Alexander, Schmitz, Gerd, Olkkonen, Vesa M.

المساهمون: Finnish Cultural Foundation, Liv och Hälsa Foundation, Academy of Finland, Sigraid Juselius Foundation, Finnish EVO funds, Magnus Ehrnrooth Foundation, Finnish Foundation for Cardiovascular Research, Finnish Diabetes Research Foundation, European Community's 7th Framework Program, Federal Ministry of Education and Research

المصدر: Physiological Reports ; volume 4, issue 1, page e12661 ; ISSN 2051-817X

الإتاحة: https://doi.org/10.14814/phy2.12661Test

المؤلفون: Ruhanen, Hanna, Perttilä, Julia, Hölttä-Vuori, Maarit, Zhou, You, Yki-Järvinen, Hannele, Ikonen, Elina, Käkelä, Reijo, Olkkonen, Vesa M.

المصدر: Journal of Lipid Research ; volume 55, issue 4, page 739-746 ; ISSN 0022-2275

مصطلحات موضوعية: Cell Biology, Endocrinology, Biochemistry

الإتاحة: https://doi.org/10.1194/jlr.m046607Test
https://api.elsevier.com/content/article/PII:S0022227520376628?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0022227520376628?httpAccept=text/plainTest

المؤلفون: Zhou, Tianhong, Li, Shiqian, Zhong, Wenbin, Vihervaara, Terhi, Béaslas, Olivier, Perttilä, Julia, Luo, Wei, Jiang, Yingliang, Lehto, Markku, Olkkonen, Vesa, Yan, Daoguang

المساهمون: Medicum, Department of Anatomy

مصطلحات موضوعية: 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: Zhou , T , Li , S , Zhong , W , Vihervaara , T , Béaslas , O , Perttilä , J , Luo , W , Jiang , Y , Lehto , M , Olkkonen , V & Yan , D 2011 , ' OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62 ' , PLoS One , vol. 6 , no. e21078 , pp. 1-12 . https://doi.org/10.1371/journal.pone.0021078Test; 79958859962; a9dd00b6-87b7-4d1a-b6ab-c42552222365; http://hdl.handle.net/10138/41617Test; 000291730000049

الإتاحة: http://hdl.handle.net/10138/41617Test