المؤلفون: Zhang, Jihui, Chen, Jie, Richardson, Jonathan P., Francis-Newton, Nicola-Jane, Lai, Pei F., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark E., Firth-Clark, Stuart, Lloyd, Steven M., Newton, Gary K., Perrior, Trevor R., Garrod, David R., Robinson, Clive

المساهمون: Wellcome Trust

المصدر: ACS Pharmacology & Translational Science ; volume 5, issue 9, page 735-751 ; ISSN 2575-9108 2575-9108

الإتاحة: https://doi.org/10.1021/acsptsci.2c00022Test

المؤلفون: te Lintel Hekkert, Maaike, Newton, Gary, Chapman, Kathryn, Aqil, Rehan, Downham, Robert, Yan, Robert, Merkus, Daphne, Whitlock, Gavin, Lane, Charlotte A.L., Cawkill, Darren, Perrior, Trevor, Duncker, Dirk J., Schneider, Michael D.

المصدر: te Lintel Hekkert , M , Newton , G , Chapman , K , Aqil , R , Downham , R , Yan , R , Merkus , D , Whitlock , G , Lane , C A L , Cawkill , D , Perrior , T , Duncker , D J & Schneider , M D 2021 , ' Preclinical trial of a MAP4K4 inhibitor to reduce infarct size in the pig : does cardioprotection in human stem cell-derived myocytes predict success in large mammals? ' , Basic Research in Cardiology , vol. 116 , no. 1 , ....

الإتاحة: https://doi.org/10.1007/s00395-021-00875-7Test
https://pure.eur.nl/en/publications/5b67a6be-da22-4cf2-8ac6-1ba760789c10Test
http://www.scopus.com/inward/record.url?scp=85106637488&partnerID=8YFLogxKTest

المؤلفون: Scott, Duncan E, Francis-Newton, Nicola J, Marsh, May E, Coyne, Anthony G, Fischer, Gerhard, Moschetti, Tommaso, Bayly, Andrew R, Sharpe, Timothy D, Haas, Kalina T, Barber, Lorraine, Valenzano, Chiara R, Srinivasan, Rajavel, Huggins, David J, Lee, Miyoung, Emery, Amy, Hardwick, Bryn, Ehebauer, Matthias, Dagostin, Claudio, Esposito, Alessandro, Pellegrini, Luca, Perrior, Trevor, McKenzie, Grahame, Blundell, Tom L, Hyvönen, Marko, Skidmore, John, Venkitaraman, Ashok R, Abell, Chris

مصطلحات موضوعية: BRCA2, DNA repair, RAD51, RAD51 inhibitor, cancer therapy, homologous recombination, protein-protein interaction inhibition, radiosensitizer, structure-guided drug discovery, BRCA2 Protein, Cell Death, Crystallography, X-Ray, DNA Damage, Humans, Models, Molecular, Molecular Conformation, Protein Binding, Rad51 Recombinase, Small Molecule Libraries, Tumor Cells, Cultured

وصف الملف: Print-Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/317313Test

الإتاحة: https://doi.org/10.17863/CAM.64431Test
https://www.repository.cam.ac.uk/handle/1810/317313Test

المؤلفون: Scott, Duncan E., Francis-Newton, Nicola J., Marsh, May E., Coyne, Anthony G., Fischer, Gerhard, Moschetti, Tommaso, Bayly, Andrew R., Sharpe, Timothy D., Haas, Kalina T., Barber, Lorraine, Valenzano, Chiara R., Srinivasan, Rajavel, Huggins, David J., Lee, Miyoung, Emery, Amy, Hardwick, Bryn, Ehebauer, Matthias, Dagostin, Claudio, Esposito, Alessandro, Pellegrini, Luca, Perrior, Trevor, McKenzie, Grahame, Blundell, Tom L., Hyvönen, Marko, Skidmore, John, Venkitaraman, Ashok R., Abell, Chris

المساهمون: Wellcome Trust, Astex Pharmaceuticals, Medical Research Council, European Synchrotron Radiation Facility

المصدر: Cell Chemical Biology ; volume 28, issue 6, page 835-847.e5 ; ISSN 2451-9456

مصطلحات موضوعية: Clinical Biochemistry, Drug Discovery, Pharmacology, Molecular Biology, Molecular Medicine, Biochemistry

الإتاحة: https://doi.org/10.1016/j.chembiol.2021.02.006Test
https://api.elsevier.com/content/article/PII:S2451945621000581?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2451945621000581?httpAccept=text/plainTest

المؤلفون: Golforoush, Pelin A., Narasimhan, Priyanka, Chaves-Guerrero, Patricia P., Lawrence, Elsa, Newton, Gary, Yan, Robert, Harding, Sian E., Perrior, Trevor, Chapman, Kathryn L., Schneider, Michael D.

المساهمون: Wellcome Trust, British Heart Foundation

المصدر: Scientific Reports ; volume 10, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41598-020-68907-1Test
https://www.nature.com/articles/s41598-020-68907-1.pdfTest
https://www.nature.com/articles/s41598-020-68907-1Test

المؤلفون: Fiedler, Lorna R., Chapman, Kathryn, Xie, Min, Maifoshie, Evie, Jenkins, Micaela, Golforoush, Pelin Arabacilar, Bellahcene, Mohamed, Noseda, Michela, Faust, Dörte, Jarvis, Ashley, Newton, Gary, Paiva, Marta Abreu, Harada, Mutsuo, Stuckey, Daniel J., Song, Weihua, Habib, Josef, Narasimhan, Priyanka, Aqil, Rehan, Sanmugalingam, Devika, Yan, Robert, Pavanello, Lorenzo, Sano, Motoaki, Wang, Sam C., Sampson, Robert D., Kanayaganam, Sunthar, Taffet, George E., Michael, Lloyd H., Entman, Mark L., Tan, Tse-Hua, Harding, Sian E., Low, Caroline M.R., Tralau-Stewart, Catherine, Perrior, Trevor, Schneider, Michael D.

المصدر: Cell Stem Cell ; volume 26, issue 3, page 458 ; ISSN 1934-5909

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Medicine

الإتاحة: https://doi.org/10.1016/j.stem.2020.01.015Test
https://api.elsevier.com/content/article/PII:S1934590920300151?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1934590920300151?httpAccept=text/plainTest

المؤلفون: Fiedler, Lorna R., Chapman, Kathryn, Xie, Min, Maifoshie, Evie, Jenkins, Micaela, Golforoush, Pelin Arabacilar, Bellahcene, Mohamed, Noseda, Michela, Faust, Dörte, Jarvis, Ashley, Newton, Gary, Paiva, Marta Abreu, Harada, Mutsuo, Stuckey, Daniel J., Song, Weihua, Habib, Josef, Narasimhan, Priyanka, Aqil, Rehan, Sanmugalingam, Devika, Yan, Robert, Pavanello, Lorenzo, Sano, Motoaki, Wang, Sam C., Sampson, Robert D., Kanayaganam, Sunthar, Taffet, George E., Michael, Lloyd H., Entman, Mark L., Tan, Tse-Hua, Harding, Sian E., Low, Caroline M.R., Tralau-Stewart, Catherine, Perrior, Trevor, Schneider, Michael D.

المساهمون: BHF, European Commission, European Research Council, MRC-BHF Cardiovascular Stem Cell Research Strategic Development Grant, MRC-Imperial Confidence in Concept Fund, NIH, Wellcome Trust

المصدر: Cell Stem Cell ; volume 24, issue 4, page 579-591.e12 ; ISSN 1934-5909

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Medicine

الإتاحة: https://doi.org/10.1016/j.stem.2019.01.013Test
https://api.elsevier.com/content/article/PII:S193459091930013X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S193459091930013X?httpAccept=text/plainTest

المؤلفون: Zhang, Jihui, Chen, Jie, Zuo, Jie, Newton, Gary, Stewart, Mark, Perrior, Trevor, Garrod, David, Robinson, Clive

المصدر: Zhang , J , Chen , J , Zuo , J , Newton , G , Stewart , M , Perrior , T , Garrod , D & Robinson , C 2018 , ' Allergen Delivery Inhibitors: Characterisation of Potent and Selective Inhibitors of Der p 1 and Their Attenuation of Airway Responses to House Dust Mite Allergens ' , International Journal of Molecular Sciences , vol. 19 , no. 10 , pp. 3166 . https://doi.org/10.3390/ijms19103166Test

الإتاحة: https://doi.org/10.3390/ijms19103166Test
https://research.manchester.ac.uk/en/publications/3318b484-2f77-40f0-aa4a-f3db5772bc62Test
http://www.mdpi.com/1422-0067/19/10/3166Test

المؤلفون: Webster, Scott P, McBride, Andrew, Binnie, Margaret, Sooy, Karen, Seckl, Jonathan R, Andrew, Ruth, Pallin, T David, Hunt, Hazel J, Perrior, Trevor R, Ruffles, Vincent S, Ketelbey, J William, Boyd, Alan, Walker, Brian R

المساهمون: Wellcome Trust

المصدر: British Journal of Pharmacology ; volume 174, issue 5, page 396-408 ; ISSN 0007-1188 1476-5381

الإتاحة: https://doi.org/10.1111/bph.13699Test