دورية أكاديمية
Genetic and antigenic characterization of influenza A/H5N1 viruses isolated from patients in Indonesia, 2008–2015
| العنوان: | Genetic and antigenic characterization of influenza A/H5N1 viruses isolated from patients in Indonesia, 2008–2015 |
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| المؤلفون: | Pawestri, H.A. (Hana A.), Nugraha, A.A. (Arie A.), Han, A.X. (Alvin X.), Pratiwi, E. (Eka), Parker, E. (Edyth), Richard, M. (Mathilde), Vliet, S. (Stefan) van der, Fouchier, R.A.M. (Ron), Muljono, D.H. (David H.), Jong, M.D. (Menno) de, Setiawaty, V. (Vivi), Eggink, D. (Dirk) |
| المصدر: | Virus Genes |
| سنة النشر: | 2020 |
| المجموعة: | RePub - Publications from Erasmus University, Rotterdam |
| مصطلحات موضوعية: | Adaptation, Antigenicity, H5N1, Highly pathogenic avian influenza virus, Vaccine, Virulence |
| الوصف: | Since the initial detection in 2003, Indonesia has reported 200 human cases of highly pathogenic avian influenza H5N1 (HPAI H5N1), associated with an exceptionally high case fatality rate (84%) compared to other geographical regions affected by other genetic clades of the virus. However, there is limited information on the genetic diversity of HPAI H5N1 viruses, especially those isolated from humans in Indonesia. In this study, the genetic and antigenic characteristics of 35 HPAI H5N1 viruses isolated from humans were analyzed. Full genome sequences were analyzed for the presence of substitutions in the receptor binding site, and po |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://repub.eur.nl/pub/127640Test; urn:hdl:1765/127640 |
| DOI: | 10.1007/s11262-020-01765-1 |
| الإتاحة: | https://doi.org/10.1007/s11262-020-01765-1Test http://repub.eur.nl/pub/127640Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.DF9D796A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s11262-020-01765-1 |
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