المؤلفون: Daniela Krummenacher, Weiping He, Bernd Kuhn, Christian Schnider, Angélica Beurier, Virginie Brom, Thulase Sivasothy, Christine Marty, Andreas Tosstorff, David S. Hewings, Stefanie Mesch, Emmanuel Pinard, Mathis Brändlin, Remo Hochstrasser, Paul Westwood, Judith Rothe, Alexandra Kronenberger, Federica Morandi, Simon Gutbier, Angelika Schuler, Dominik Heer, Ludivine Esteves Gloria, Lisa Joedicke, Markus G. Rudolph, Lutz Müller, Fiona Grüninger, Karlheinz Baumann, Senthilvelrajan Kaniyappan, Nenad Manevski, Björn Bartels

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Chemical Sciences not elsewhere classified, tau n368 fragment, prone tau fragments, promising therapeutic strategy, phosphorylated tau fragments, irreversible binding mode, brain penetrant inhibitors, widespread form, vivo <, vitro <, tangles consist, series starting, reversible molecules, pathological hallmarks, orally bioavailable, orally available, nfts ), neurofibrillary tangles, generates aggregation

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_Orally_Available_and_Brain_Penetrant_AEP_Inhibitors/24800481Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01804.s001Test
https://figshare.com/articles/journal_contribution/Discovery_of_Orally_Available_and_Brain_Penetrant_AEP_Inhibitors/24800481Test

المؤلفون: John Paul Westwood, Marie Scully

المصدر: Therapeutic Advances in Hematology, Vol 13 (2022)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2040-6215Test

الوصول الحر: https://doaj.org/article/0143d637048241a5a0ea44dc4fbedff1Test

المؤلفون: Mahima Kapoor, Ian Hunt, Jennifer Spillane, Laura Jayne Bonnett, Elspeth Jane Hutton, James McFadyen, John-Paul Westwood, Michael P Lunn, Aisling S Carr, Mary M Reilly

المصدر: Journal of Neurology, Neurosurgery & Psychiatry. 93:876-885

مصطلحات موضوعية: Psychiatry and Mental health, Diabetes Mellitus, Type 2, Risk Factors, Humans, Immunoglobulins, Intravenous, Surgery, Venous Thromboembolism, Neurology (clinical), United Kingdom, Biological Specimen Banks, Retrospective Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb016e665f35e3e46c94f055a8dc5a0Test
https://doi.org/10.1136/jnnp-2022-328881Test

المؤلفون: Fieke E.M. Froeling, Sarah Bradley, Judith Dixon, Rosie Upstill-Goddard, Paul Grimwood, Paul Westwood, Andrew V. Biankin, Philip A. Beer, Janet Graham, Juan Valle, David K. Chang

المصدر: Pancreatology. 23:e4-e5

مصطلحات موضوعية: Hepatology, Endocrinology, Diabetes and Metabolism, Gastroenterology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::74e5a8186e02765f38abb45d8857ddd0Test
https://doi.org/10.1016/j.pan.2023.04.019Test

المؤلفون: Nithya Prasannan, Mari Thomas, Matthew James Stubbs, John-Paul Westwood, Rens de Groot, Deepak Singh, Marie Scully

المصدر: Blood.

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2b0a0f3488da7e5eb027d49fe669078aTest
https://doi.org/10.1182/blood.2022018847Test

المؤلفون: Andrew J. Doyle, Matthew J. Stubbs, Tina Dutt, Will Lester, Will Thomas, Joost van Veen, Joannes Hermans, Tanya Cranfield, Quentin A. Hill, Amanda Clark, Catherine Bagot, Steven Austin, John-Paul Westwood, Mari Thomas, Marie Scully

المصدر: Blood.

مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62df594e880e852ea47fc557667ea69Test
https://pubmed.ncbi.nlm.nih.gov/36322971Test

المؤلفون: Lynne J, Hocking, Claire, Andrews, Christine, Armstrong, Morad, Ansari, David, Baty, Jonathan, Berg, Therese, Bradley, Caroline, Clark, Austin, Diamond, Jill, Doherty, Anne, Lampe, Ruth, McGowan, David J, Moore, Dawn, O'Sullivan, Andrew, Purvis, Javier, Santoyo-Lopez, Paul, Westwood, Michael, Abbott, Nicola, Williams, Timothy J, Aitman, Margo, Whiteford

المصدر: Hocking, L J, Andrews, C, Armstrong, C, Ansari, M, Baty, D, Berg, J, Bradley, T, Clark, C, Diamond, A, Doherty, J, Lampe, A, McGowan, R, Moore, D J, O'Sullivan, D, Purvis, A, Santoyo-Lopez, J, Westwood, P, Abbott, M, Williams, N & Aitman, T J & Miedzybrodzka, Z 2022, ' Genome sequencing with gene panel-based analysis for rare inherited conditions in a publicly funded healthcare system: implications for future testing ', European Journal of Human Genetics, vol. 31 . https://doi.org/10.1038/s41431-022-01226-3Test

مصطلحات موضوعية: Genetics, Genetics (clinical)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09a3b01751706f954ef04300960a4c0Test
https://pubmed.ncbi.nlm.nih.gov/36474026Test

المؤلفون: Chiara Vendramin, Mari Thomas, John-Paul Westwood, Marie Scully

المصدر: TH Open, Vol 02, Iss 03, Pp e329-e333 (2018)

مصطلحات موضوعية: adamts13 protein, human plasma, anti-adamts13 inhibitors, bethesda assay, enzyme-linked immunosorbent assay, thrombotic thrombocytopenic purpura, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2512-9465Test

الوصول الحر: https://doaj.org/article/cae5339a63394176bb9c2e2a2cb7536eTest

المؤلفون: Masanori Matsumoto, John-Paul Westwood, Johanna A. Kremer Hovinga, Kenneth D. Friedman, Yoshiaki Tomiyama, Adam Cuker, Katerina Pavenski, James N. George, Flora Peyvandi, Javier de la Rubia, Spero R. Cataland, Paul Knoebl, Agnès Veyradier, Paul Coppo, Kazuya Sakai, Marie Scully, Mari Thomas, Bernhard Lämmle, Ravi Sarode

المساهمون: Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Recherche clinique appliquée à l'hématologie (URP_3518), Université de Paris (UP), Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris]

المصدر: Blood
Blood, American Society of Hematology, 2021, 137 (14), pp.1855-1861. ⟨10.1182/blood.2020009150⟩

مصطلحات موضوعية: Adult, 0301 basic medicine, medicine.medical_specialty, Consensus, Thrombotic microangiopathy, Exacerbation, [SDV]Life Sciences [q-bio], Immunology, Thrombotic thrombocytopenic purpura, MEDLINE, ADAMTS13 Protein, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Fibrinolytic Agents, Recurrence, hemic and lymphatic diseases, von Willebrand Factor, Humans, Medicine, Clinical significance, Intensive care medicine, Plasma Exchange, Purpura, Thrombotic Thrombocytopenic, Platelet Count, business.industry, Disease Management, Cell Biology, Hematology, Single-Domain Antibodies, medicine.disease, ADAMTS13, 3. Good health, Discontinuation, Treatment Outcome, 030104 developmental biology, Female, Caplacizumab, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d707207a4f9c8af7579fa4937f906b25Test
https://doi.org/10.1182/blood.2020009150Test

المؤلفون: Ian Tan, Anand S. Pandit, Shivani Joshi, Mehdi Khan, Zara Sayar, John-Paul Westwood, Hannah Cohen, Ahmed K. Toma

المصدر: British journal of neurosurgery. 36(3)

مصطلحات موضوعية: Elective Surgical Procedures, Anticoagulants, Humans, Surgery, Hemorrhage, Neurology (clinical), General Medicine, Venous Thromboembolism, Retrospective Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1a0e41ccf18ed2b5fe853ce212109aTest
https://pubmed.ncbi.nlm.nih.gov/35445634Test