دورية أكاديمية

A Comparative Study of 0.25% Ropivacaine with fentanyl and 0.25% Ropivacaine with Midazolam in Paediatric Single Shot Caudal Block.

التفاصيل البيبلوغرافية
العنوان: A Comparative Study of 0.25% Ropivacaine with fentanyl and 0.25% Ropivacaine with Midazolam in Paediatric Single Shot Caudal Block.
المؤلفون: Choubey, Puja, Verma, Brajendra, Paul, Ranadhee
المصدر: European Journal of Cardiovascular Medicine; 2024, Vol. 14 Issue 2, p654-660, 7p
مصطلحات موضوعية: POSTOPERATIVE pain treatment, ROPIVACAINE, FENTANYL, MIDAZOLAM, PEDIATRIC surgery, PREMEDICATION
مستخلص: Background: Effective postoperative pain management in children is a pivotal aspect of pediatric surgery, with caudal blocks being a commonly employed technique. This study aimed to compare the efficacy and safety of two adjuvant drugs, Fentanyl and Midazolam, when combined with Ropivacaine for pediatric single-shot caudal blocks. Methods: A total of 80 pediatric patients scheduled for infraumbilical surgeries were randomized into two groups to receive either Ropivacaine with Fentanyl or Ropivacaine with Midazolam. The primary outcomes measured were postoperative pain scores using the CHIPPS scale and the duration of analgesia. Secondary outcomes included the incidence of side effects and the requirement for additional postoperative analgesics. Results: The Ropivacaine + Fentanyl group exhibited significantly lower pain scores at 2, 4, 6, 12, and 24 hours post-surgery (p-values 0.03, 0.04, 0.01, 0.05, and 0.02, respectively) compared to the Ropivacaine + Midazolam group. The duration of analgesia was significantly longer in the Ropivacaine + Fentanyl group (8 ± 1.5 hours) than in the Ropivacaine + Midazolam group (6 ± 1.7 hours, p < 0.001). There were no significant differences in the incidence of side effects or the need for additional postoperative analgesics between the two groups. Conclusion: The combination of Ropivacaine and Fentanyl for pediatric caudal blocks significantly improves the quality and duration of postoperative analgesia without increasing adverse effects, making it a superior choice over Ropivacaine with Midazolam. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index