المؤلفون: Theys, Jan, Patterson, Adam V., Mowday, Alexandra M.

المصدر: Theys , J , Patterson , A V & Mowday , A M 2024 , ' Clostridium Bacteria : Harnessing Tumour Necrosis for Targeted Gene Delivery ' , Molecular Diagnosis & Therapy , vol. 28 , no. 2 , pp. 141-151 . https://doi.org/10.1007/s40291-024-00695-0Test

مصطلحات موضوعية: ENZYME PRODRUG THERAPY, NOVYI-NT SPORES, ANAEROBIC-BACTERIA, RECOMBINANT INTERLEUKIN-2, INTRATUMORAL INJECTION, NITROREDUCTASE ENZYME, CYTOSINE DEAMINASE, ANTITUMOR-ACTIVITY, ESCHERICHIA-COLI, PHASE-I

العلاقة: https://cris.maastrichtuniversity.nl/en/publications/9011784f-304c-4be0-9e4a-4dbbaf9da42cTest

الإتاحة: https://doi.org/10.1007/s40291-024-00695-0Test
https://cris.maastrichtuniversity.nl/en/publications/9011784f-304c-4be0-9e4a-4dbbaf9da42cTest

المؤلفون: Mowday, Alexandra M., van de Laak, Jella M., Fu, Zhe, Henare, Kimiora L., Dubois, Ludwig, Lambin, Philippe, Theys, Jan, Patterson, Adam V.

المساهمون: Health Research Council of New Zealand, KWF Kankerbestrijding, ZonMw

المصدر: Critical Reviews in Microbiology ; page 1-16 ; ISSN 1040-841X 1549-7828

الإتاحة: https://doi.org/10.1080/1040841x.2024.2311653Test

المؤلفون: Jackson-Patel, Victoria, Liu, Emily, Bull, Matthew R, Ashoorzadeh, Amir, Bogle, Gib, Wolfram, Anna, Hicks, Kevin O, Smaill, Jeff B, Patterson, Adam V

مصطلحات موضوعية: CP-506, PR-104 (PubChem CID: 11455973), PR-104A (PubChem CID: 9848786), SN36506, agent-based modelling (ABM), bystander effect, hypoxia-activated prodrug, multicellular spheroids, 2 Aetiology, 2.1 Biological and endogenous factors, Cancer, Science & Technology, Life Sciences & Biomedicine, Pharmacology & Pharmacy, PR-104 (PubChem CID, 11455973), PR-104A (PubChem CID, 9848786), EXTRAVASCULAR TRANSPORT, CANCER-THERAPY, PR-104A, TIRAPAZAMINE, OXIDOREDUCTASE, SORAFENIB, 1115 Pharmacology and Pharmaceutical Sciences

جغرافية الموضوع: Switzerland

وصف الملف: Electronic-eCollection; application/pdf

العلاقة: Frontiers in pharmacology; (2022). Frontiers in Pharmacology, 13, 803602-.; https://hdl.handle.net/2292/62944Test; 35211015 (pubmed); 803602

الإتاحة: https://doi.org/10.3389/fphar.2022.803602Test
https://hdl.handle.net/2292/62944Test

المؤلفون: Sharrock, Abigail V., Mumm, Jeff S., Williams, Elsie M., Čėnas, Narimantas, Smaill, Jeff B., Patterson, Adam V., Ackerley, David F., Bagdžiūnas, Gintautas, Arcus, Vickery L.

المصدر: International Journal of Molecular Sciences; Jun2024, Vol. 25 Issue 12, p6593, 16p

مصطلحات موضوعية: PRODRUGS, BACTERIAL enzymes, ESCHERICHIA coli, HYDROGEN bonding interactions, BIOCHEMICAL substrates, GROUP 15 elements

المؤلفون: Yang, Fang, Lin, Qianmeng, Song, Xiaojuan, Huang, Huisi, Chen, Xiaojuan, Tan, Jianwen, Li, Yun, Zhou, Yang, Tu, Zhengchao, Du, Hongli, Zhang, Zhi-min, Ortega, Raquel, Lin, Xiaojing, Patterson, Adam V., Smaill, Jeff B., Chen, Yongheng, Lu, Xiaoyun

المساهمون: State Key Laboratory of Respiratory Disease, Basic and Applied Basic Research Foundation of Guangdong Province, Health Research Council of New Zealand, Jinan University, National Natural Science Foundation of China, Cancer Society Auckland Northland, China–Maurice Wilkins Centre Collaborative Research Programme

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 4, page 2667-2689 ; ISSN 0022-2623 1520-4804

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01810Test

المؤلفون: Theys, Jan, Patterson, Adam V., Mowday, Alexandra M.

المصدر: Molecular Diagnosis & Therapy; Mar2024, Vol. 28 Issue 2, p141-151, 11p

مصطلحات موضوعية: CLOSTRIDIUM, CLOSTRIDIUM acetobutylicum, CLOSTRIDIA, IMMUNE checkpoint inhibitors, ANAEROBIC bacteria, GENETIC techniques, GENE expression

المؤلفون: Mowday, Alexandra M., Dubois, Ludwig J., Kubiak, Aleksandra M., Chan-Hyams, Jasmine V. E., Guise, Christopher P., Ashoorzadeh, Amir, Lambin, Philippe, Ackerley, David F., Smaill, Jeff B., Minton, Nigel P., Theys, Jan, Patterson, Adam V.

المصدر: Mowday , A M , Dubois , L J , Kubiak , A M , Chan-Hyams , J V E , Guise , C P , Ashoorzadeh , A , Lambin , P , Ackerley , D F , Smaill , J B , Minton , N P , Theys , J & Patterson , A V 2022 , ' Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours ' , Cancer Gene Therapy , vol. 29 , no. 2 , pp. 178-188 . https://doi.org/10.1038/s41417-021-00296-7Test

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41417-021-00296-7Test
https://cris.maastrichtuniversity.nl/en/publications/df7cb783-c7d9-475e-9337-a77f79540da8Test
https://cris.maastrichtuniversity.nl/ws/files/63828225/Dubois_2021_Use_of_an_optimised_enzymeprodrug_combination_for_Clostridia.pdfTest

المؤلفون: Jackson-Patel, Victoria, Liu, Emily, Bull, Matthew R., Ashoorzadeh, Amir, Bogle, Gib, Wolfram, Anna, Hicks, Kevin O., Smaill, Jeff B., Patterson, Adam V.

المساهمون: Health Research Council of New Zealand

المصدر: Frontiers in Pharmacology ; volume 13 ; ISSN 1663-9812

مصطلحات موضوعية: Pharmacology (medical), Pharmacology

الإتاحة: https://doi.org/10.3389/fphar.2022.803602Test

المؤلفون: Patterson, Adam V.

مصطلحات موضوعية: 615.1, Reductive metabolism, Gene therapy

الإتاحة: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267352Test

المؤلفون: Ashoorzadeh, Amir, Mowday, Alexandra M., Abbattista, Maria R., Guise, Christopher P., Bull, Matthew R., Silva, Shevan, Patterson, Adam V., Smaill, Jeff B.

المصدر: ACS Medicinal Chemistry Letters; 11/9/2023, Vol. 14 Issue 11, p1517-1523, 7p