-
1دورية أكاديمية
المؤلفون: Michel Bidet, Olivier Joubert, Benoit Lacombe, Marine Ciantar, Rony Nehmé, Patrick Mollat, Lionel Brétillon, Hélène Faure, Robert Bittman, Martial Ruat, Isabelle Mus-Veteau
المصدر: PLoS ONE, Vol 6, Iss 9, p e23834 (2011)
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC3169562?pdf=renderTest; https://doaj.org/toc/1932-6203Test
-
2دورية أكاديمية
المؤلفون: Taouès Temal-Laib, Christophe Peixoto, Nicolas Desroy, Elsa De Lemos, Florence Bonnaterre, Natacha Bienvenu, Olivier Picolet, Eric Sartori, Denis Bucher, Miriam López-Ramos, Carlos Roca Magadán, Wendy Laenen, Thomas Flower, Patrick Mollat, Olivier Bugaud, Robert Touitou, Anna Pereira Fernandes, Stephanie Lavazais, Alain Monjardet, Monica Borgonovi, Romain Gosmini, Reginald Brys, David Amantini, Steve De Vos, Martin Andrews
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Cancer, Inorganic Chemistry, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, throughput screening campaign, protein kinase amp, activated protein kinase, immunoregulatory cytokine production, clinical candidate glpg3312, pharmacokinetic investigations led, pharmacokinetic properties, immunoregulatory activities, glpg3312 demonstrated, vivo <, vitro <, threonine kinases, therapeutic potential, subsequent hit, sik inhibitor, mouse models, inducible kinases, dual mechanism
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01428.s001Test
https://figshare.com/articles/journal_contribution/Optimization_of_Selectivity_and_Pharmacokinetic_Properties_of_Salt_Inducible_Kinase_Inhibitors_that_Led_to_the_Discovery_of_Pan-SIK_Inhibitor_GLPG3312/24904973Test -
3دورية أكاديمية
المؤلفون: Franck Brebion (2439052), Romain Gosmini (1738168), Pierre Deprez (1705699), Marie Varin (2479900), Christophe Peixoto (2035117), Luke Alvey (2035129), Hélène Jary (2035114), Natacha Bienvenu (1705657), Nicolas Triballeau (1400671), Roland Blanque (3989681), Céline Cottereaux (9412031), Thierry Christophe (242276), Nele Vandervoort (3989705), Patrick Mollat (206614), Robert Touitou (4376779), Philip Leonard (1621432), Frédéric De Ceuninck (1417306), Iuliana Botez (1701322), Alain Monjardet (3989687), Ellen van der Aar (3989690), David Amantini (232220)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, phase 2, knee OA, 1.5 μ M, DMOAD, hydantoin series, Biochemical activity, cocrystal structure, anticatabolic activity, IC 50, glycosaminoglycan release, disease-modifying osteoarthritis, mouse cartilage explants, NCT, GLPG, aggrecanase ADAMTS, HTS, fluorescence-based assay, AGC ELISA
-
4Data from The Hedgehog Receptor Patched Functions in Multidrug Transport and Chemotherapy Resistance
المؤلفون: Isabelle Mus-Veteau, Patrick Mollat, Hélène Guizouarn, Patrick Martin, Amandine Tomico, Michel Bidet
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8b5b5da3efb1e0104e45fe998bbed57fTest
https://doi.org/10.1158/1541-7786.c.6541479Test -
5
-
6
-
7
-
8
-
9
-
10
المؤلفون: L. Lepescheux, R. Gosmini, F. De Ceuninck, Thierry Christophe, E. van der Aar, I. Botez, Nele Vandervoort, Pierre Deprez, D. Amantini, Roland Blanque, D. Merciris, Robert Touitou, Philippe Clément-Lacroix, C. Cottereaux, S. Meurisse, Patrick Mollat, F. Brebion, D. Comas, Christopher B. Little, Margaret M. Smith
المصدر: Osteoarthritis and Cartilage. 30:291-301
مصطلحات موضوعية: Metalloproteinase, biology, Chemistry, Cartilage, Biomedical Engineering, Osteoarthritis, Pharmacology, medicine.disease, Piperazines, Rats, Glycosaminoglycan, Mice, medicine.anatomical_structure, Rheumatology, Proteoglycan, In vivo, biology.protein, medicine, Animals, Humans, Orthopedics and Sports Medicine, ADAMTS5 Protein, Aggrecan, Aggrecanase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3703c4b9781633c63762275b997650Test
https://doi.org/10.1016/j.joca.2021.08.012Test