المؤلفون: Corcoran, Sean R, Phelan, James D, Choi, Jaewoo, Shevchenko, Galina, Fenner, Rachel E, Yu, Xin, Scheich, Sebastian, Hsiao, Tony, Morris, Vivian M, Papachristou, Evangelia K, Kishore, Kamal, D'Santos, Clive S, Ji, Yanlong, Pittaluga, Stefania, Wright, George W, Urlaub, Henning, Pan, Kuan-Ting, Oellerich, Thomas, Muppidi, Jagan, Hodson, Daniel J, Staudt, Louis M

مصطلحات موضوعية: 32 Biomedical and Clinical Sciences, 3201 Cardiovascular Medicine and Haematology, 3211 Oncology and Carcinogenesis, Precision Medicine, Hematology, Lymphatic Research, Cancer, Rare Diseases, Genetics, FOS Biological sciences, Lymphoma, Orphan Drug, 3 Good Health and Well Being

الإتاحة: https://doi.org/10.17863/cam.108069Test
https://www.repository.cam.ac.uk/handle/1810/367497Test

المؤلفون: Demond, Hannah, Hanna, Courtney W, Castillo-Fernandez, Juan, Santos, Fátima, Papachristou, Evangelia K, Segonds-Pichon, Anne, Kishore, Kamal, Andrews, Simon, D'Santos, Clive S, Kelsey, Gavin

مصطلحات موضوعية: Animals, Mice, Multiomics, Proteome, Histone-Lysine N-Methyltransferase, Oogenesis, Oocytes

وصف الملف: Print-Electronic; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/347478Test

الإتاحة: https://doi.org/10.17863/CAM.94893Test
https://www.repository.cam.ac.uk/handle/1810/347478Test

المؤلفون: Pavlou, Sofia, Foskolou, Stefanie, Patikas, Nikolaos, Field, Sarah F., Papachristou, Evangelia K., Santos, Clive D’, Edwards, Abigail R., Kishore, Kamal, Ansari, Rizwan, Rajan, Sandeep S., Fernandes, Hugo J. R., Metzakopian, Emmanouil

المساهمون: Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK Dementia Research Institute

المصدر: Scientific Reports ; volume 13, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41598-023-31141-6Test
https://www.nature.com/articles/s41598-023-31141-6.pdfTest
https://www.nature.com/articles/s41598-023-31141-6Test

المؤلفون: Knott, Simon RV, Wagenblast, Elvin, Khan, Showkhin, Kim, Sun Y, Soto, Mar, Wagner, Michel, Turgeon, Marc-Olivier, Fish, Lisa, Erard, Nicolas, Gable, Annika L, Maceli, Ashley R, Dickopf, Steffen, Papachristou, Evangelia K, D’Santos, Clive S, Carey, Lisa A, Wilkinson, John E, Harrell, J Chuck, Perou, Charles M, Goodarzi, Hani, Poulogiannis, George, Hannon, Gregory J

المصدر: Nature. 554(7692)

مصطلحات موضوعية: Ecological Applications, Biomedical and Clinical Sciences, Environmental Sciences, Oncology and Carcinogenesis, Breast Cancer, Cancer, Animals, Asparaginase, Asparagine, Aspartate-Ammonia Ligase, Biological Availability, Breast Neoplasms, Cell Line, Tumor, Disease Models, Animal, Disease Progression, Epithelial-Mesenchymal Transition, Female, Humans, Lung Neoplasms, Male, Mice, Neoplasm Invasiveness, Neoplasm Metastasis, Prognosis, Prostatic Neoplasms, RNA Interference, Reproducibility of Results, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4cw067kbTest

المؤلفون: Patel, Saroor A, Hirosue, Shoko, Rodrigues, Paulo, Vojtasova, Erika, Richardson, Emma K, Ge, Jianfeng, Syafruddin, Saiful E, Speed, Alyson, Papachristou, Evangelia K, Baker, David, Clarke, David, Purvis, Stephenie, Wesolowski, Ludovic, Dyas, Anna, Castillon, Leticia, Caraffini, Veronica, Bihary, Dóra, Yong, Cissy, Harrison, David J, Stewart, Grant D, Machiela, Mitchell J, Purdue, Mark P, Chanock, Stephen J, Warren, Anne Y, Samarajiwa, Shamith A, Carroll, Jason S, Vanharanta, Sakari

المصدر: Patel , S A , Hirosue , S , Rodrigues , P , Vojtasova , E , Richardson , E K , Ge , J , Syafruddin , S E , Speed , A , Papachristou , E K , Baker , D , Clarke , D , Purvis , S , Wesolowski , L , Dyas , A , Castillon , L , Caraffini , V , Bihary , D , Yong , C , Harrison , D J , Stewart , G D , Machiela , M J , Purdue , M P , Chanock , S ....

وصف الملف: application/pdf

العلاقة: https://research-portal.st-andrews.ac.uk/en/researchoutput/the-renal-lineage-factor-pax8-controls-oncogenic-signalling-in-kidney-cancerTest(83d8930d-20e8-4886-ace1-29fcb8e106ed).html

الإتاحة: https://doi.org/10.1038/s41586-022-04809-8Test
https://research-portal.st-andrews.ac.uk/en/researchoutput/the-renal-lineage-factor-pax8-controls-oncogenic-signalling-in-kidney-cancerTest(83d8930d-20e8-4886-ace1-29fcb8e106ed).html
https://research-repository.st-andrews.ac.uk/bitstream/10023/25558/1/Patel_2022_Nature_Renal_lineage_factor_CC.pdfTest

المؤلفون: Patel, Saroor A., Hirosue, Shoko, Rodrigues, Paulo, Vojtasova, Erika, Richardson, Emma K., Ge, Jianfeng, Syafruddin, Saiful E., Speed, Alyson, Papachristou, Evangelia K., Baker, David, Clarke, David, Purvis, Stephenie, Wesolowski, Ludovic, Dyas, Anna, Castillon, Leticia, Caraffini, Veronica, Bihary, Dora, Yong, Cissy, Harrison, David J., Stewart, Grant D., Machiela, Mitchell J., Purdue, Mark P., Chanock, Stephen J., Warren, Anne Y., Samarajiwa, Shamith A., Carroll, Jason S., Vanharanta, Sakari

المساهمون: CAN-PRO - Translational Cancer Medicine Program, Department of Physiology, Faculty of Medicine, University of Helsinki

مصطلحات موضوعية: CYCLIN D1, HIF, SUSCEPTIBILITY, BINDING, SPECIFICITY, PROMOTES, ENHANCER, TARGET, GENE, 3122 Cancers

وصف الملف: application/pdf

العلاقة: We thank R. Schulte, C. Cossetti and G. Grondys-Kotarba from the Cambridge Institute for Medical Research Flow Cytometry Core Facility for assistance with cell sorting; P. Coupland and staff at the CRUK CI Genomics and Bioinformatics Core for sequencing and analysis; A. Obenauf, C. David and C. Frezza for critical reading of the manuscript; and M. Linehan for the UOK101 cells. FISH was performed at the Cambridge Genomics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. G.D.S. is supported by the Mark Foundation for Cancer Research. G.D.S. and A.Y.W. are supported by the Cancer Research UK Cambridge Centre (C9685/A25177). J.S.C. acknowledges support from the University of Cambridge, Cancer Research UK core funding (grants A20411, A31344, A29580 and DRCPGM\100088) and Hutchison Whampoa. G.D.S., A.Y.W., J.S.C. and the Human Research Tissue Bank were supported by the NIHR Cambridge Biomedical Research Centre (BRC-1215-20014). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. The GWAS analysis performed by M.J.M., M.P.P. and S.J.C. was supported by the Intramural Research Program of the National Cancer Institute, part of the National Institutes of Health. The Renal Cancer Research Fund supported the tissue microarray studies (D.J.H.). S.H. received a PhD studentship from the Rosetrees Trust. This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 955951. This work was supported by the Medical Research Council (MC_UU_12022/7 and MC_UU_12022/10) and Kidney Research UK (RP_033_20170303).; Patel , S A , Hirosue , S , Rodrigues , P , Vojtasova , E , Richardson , E K , Ge , J , Syafruddin , S E , Speed , A , Papachristou , E K , Baker , D , Clarke , D , Purvis , S , Wesolowski , L , Dyas , A , Castillon , L , Caraffini , V , Bihary , D , Yong , C , Harrison , D J , Stewart , G D , Machiela , M J , Purdue , M P , Chanock , S J , Warren , A Y , Samarajiwa , S A , Carroll , J S & Vanharanta , S 2022 , ' The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer ' , Nature , vol. 606 , no. 7916 , pp. 999-+ . https://doi.org/10.1038/s41586-022-04809-8Test; ORCID: /0000-0001-5619-7963/work/127004272; 4a025a02-750d-49af-9bed-cb5c5f3aa3fb; http://hdl.handle.net/10138/346323Test; 000808011000003

الإتاحة: http://hdl.handle.net/10138/346323Test

المؤلفون: Simeoni, Fabrizio, Romero-Camarero, Isabel, Camera, Francesco, Amaral, Fabio MR, Sinclair, Oliver J, Papachristou, Evangelia K, Spencer, Gary J, Lie-A-Ling, Michael, Lacaud, Georges, Wiseman, Daniel H, Carroll, Jason S, Somervaille, Tim CP

مصطلحات موضوعية: FOXC1, Groucho, RUNX1, TLE3, acute myeloid leukemia, CCAAT-Enhancer-Binding Proteins, Cell Differentiation, Cell Line, Tumor, Chromatin, Co-Repressor Proteins, Core Binding Factor Alpha 2 Subunit, Enhancer Elements, Genetic, Forkhead Transcription Factors, Histone Deacetylase 1, Humans, Kruppel-Like Transcription Factors, Leukemia, Myeloid, Acute, Monocytes, Promoter Regions, Protein Binding, Protein Domains, Proto-Oncogene Proteins c-myc, RNA Interference, RNA, Small Interfering, Up-Regulation

وصف الملف: Print; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/334614Test

الإتاحة: https://doi.org/10.17863/CAM.82033Test
https://www.repository.cam.ac.uk/handle/1810/334614Test

المؤلفون: Broome, Rebecca, Chernukhin, Igor, Jamieson, Stacey, Kishore, Kamal, Papachristou, Evangelia K., Mao, Shi-Qing, Tejedo, Carmen Gonzalez, Mahtey, Areeb, Theodorou, Vasiliki, Groen, Arnoud J., D'Santos, Clive, Balasubramanian, Shankar, Farcas, Anca Madalina, Siersbaek, Rasmus, Carroll, Jason S.

المصدر: Broome , R , Chernukhin , I , Jamieson , S , Kishore , K , Papachristou , E K , Mao , S-Q , Tejedo , C G , Mahtey , A , Theodorou , V , Groen , A J , D'Santos , C , Balasubramanian , S , Farcas , A M , Siersbaek , R & Carroll , J S 2021 , ' TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions ' , Cell Reports , vol. 34 , no. 8 , 108776 ....

مصطلحات موضوعية: 5hmC, GATA3, TET2, enhancers, estrogen receptor, gene regulation

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/e61346f5-fddb-473c-ad62-620463376460Test

الإتاحة: https://doi.org/10.1016/j.celrep.2021.108776Test
https://portal.findresearcher.sdu.dk/da/publications/e61346f5-fddb-473c-ad62-620463376460Test
https://findresearcher.sdu.dk/ws/files/181897485/PIIS2211124721000899.pdfTest

المؤلفون: Memon, Danish, Gill, Michael B., Papachristou, Evangelia K., Ochoa, David, D’Santos, Clive S., Miller, Martin L., Beltrao, Pedro, id_orcid:0 000-0002-2724-7703

المصدر: Cell Reports, 35 (7)

مصطلحات موضوعية: cancer, copy number aberrations, genetic associations, phospho-regulation, kinase addiction, precision medicine

وصف الملف: application/application/pdf

العلاقة: http://hdl.handle.net/20.500.11850/531935Test

الإتاحة: https://doi.org/20.500.11850/531935Test
https://doi.org/10.3929/ethz-b-000531935Test
https://doi.org/10.1016/j.celrep.2021.109155Test
https://hdl.handle.net/20.500.11850/531935Test

المؤلفون: Simeoni, Fabrizio, Romero-Camarero, Isabel, Camera, Francesco, Amaral, Fabio M.R., Sinclair, Oliver J., Papachristou, Evangelia K., Spencer, Gary J., Lie-A-Ling, Michael, Lacaud, Georges, Wiseman, Daniel H., Carroll, Jason S., Somervaille, Tim C.P.

المساهمون: Hutchison Whampoa Limited, Cancer Research UK, Kay Kendall Leukaemia Fund, University of Cambridge

المصدر: Cell Reports ; volume 36, issue 12, page 109725 ; ISSN 2211-1247

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

الإتاحة: https://doi.org/10.1016/j.celrep.2021.109725Test
https://api.elsevier.com/content/article/PII:S2211124721011748?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2211124721011748?httpAccept=text/plainTest