المؤلفون: Gelin, Muriel, Paoletti, Julie, Nahori, Marie-Anne, Huteau, Valeŕie, Leseigneur, Clarisse, Jouvion, Greǵory, Dugué, Laurence, Clément, David, Pons, Jean-Luc, Assairi, Liliane, Pochet, Sylvie, Labesse, Gilles, Dussurget, Olivier

المساهمون: Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Toxines bactériennes - Bacterial Toxins, Institut Pasteur Paris (IP), Yersinia, Université Sorbonne Paris Cité (USPC), Neuropathologie expérimentale - Experimental neuropathology, Institut Pasteur Paris (IP)-Université Paris Descartes - Paris 5 (UPD5), Maladies génétiques d'expression pédiatrique (U933), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Trousseau APHP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Trousseau APHP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Imagerie intégrative de la molécule à l'organisme, Institut Curie Paris -Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Sud - Paris 11 (UP11), This work was supported by the Agence Nationale de la Recherche (grants ANR-06-BLAN-0324, ANR-11-EMM-0019, and ANR-17-CE18-0011-02), the Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur and Institut Curie. DC and CL acknowledge ANR for financial support (ANR-17-CE18-0011-02). We also acknowledge support from the French Infrastructure for Integrated Structural Biology (FRISBI) ANR-10-INSB-05-01 and Idex UP2019, ANR-06-BLAN-0324,Gram(+) NADK,Rational design and in situ selection of drug targetting NAD kinases from Gram(+) bacterial pathogens(2006), ANR-11-EMMA-0019,ANAKIN (Anti-NAd-Kinase),Nouveaux composés antibactériens ciblant la NAD kinase(2011), ANR-17-CE18-0011,NADKiller,NADK : une nouvelle cible bactérienne pour le développement d'antibiotiques(2017), ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)

المصدر: EISSN: 2373-8227 ; ACS Infectious Diseases ; https://hal.science/hal-02573173Test ; ACS Infectious Diseases, 2020, 6 (3), ⟨10.1021/acsinfecdis.9b00368⟩

مصطلحات موضوعية: antibacterial compound, adenosine derivative, staphylococci, bacterial NAD kinase, MRSA, [SDV]Life Sciences [q-bio], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32017533; hal-02573173; https://hal.science/hal-02573173Test; https://hal.science/hal-02573173/documentTest; https://hal.science/hal-02573173/file/proof.pdfTest; PUBMED: 32017533; WOS: 000526415000008

الإتاحة: https://doi.org/10.1021/acsinfecdis.9b00368Test
https://hal.science/hal-02573173Test
https://hal.science/hal-02573173/documentTest
https://hal.science/hal-02573173/file/proof.pdfTest

المؤلفون: Danilin, Sabrina, Amiable, Claire, Coquard, Catherine, Kaminski, Pierre-Alexandre, Paoletti, Julie, Rothhut, Sylvie, Hamaidi, Iméne, Béraud, Claire, Lindner, Véronique, Lang, Hervé, Pochet, Sylvie, Massfelder, Thierry

المصدر: Journal of Urology ; volume 197, issue 4S ; ISSN 0022-5347 1527-3792

الإتاحة: https://doi.org/10.1016/j.juro.2017.02.2712Test
https://api.elsevier.com/content/article/PII:S0022534717341782?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0022534717341782?httpAccept=text/plainTest

المؤلفون: Paoletti, Julie, Assairi, Liliane, Gelin, Muriel, Huteau, Valerie, Nahori, Marie -Anne, Dussurget, Olivier, Labesse, Gilles, Pochet, Sylvie

المساهمون: Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), U759 Unité Imagerie intégrative, Institut Curie Paris, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM), Interactions Bactéries-Cellules (UIBC), Institut National de la Recherche Agronomique (INRA)-Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Sorbonne Paris Cité (USPC), Agence Nationale de la Recherche ANR-06-BLAN-0324, ANR-11-EMM-0019, French Infrastructure for Integrated Structural Biology (FRISBI) ANR-10-INSB-05-01, ANR ANR-11-EMM-0019, ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010), ANR-11-EMMA-0019,ANAKIN (Anti-NAd-Kinase),Nouveaux composés antibactériens ciblant la NAD kinase(2011), ANR-06-BLAN-0324,Gram(+) NADK,Rational design and in situ selection of drug targetting NAD kinases from Gram(+) bacterial pathogens(2006)

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Adenosine analogue, Antibacterial, Inhibitor, NAD kinase, X-ray crystallography, MESH: Adenosine/chemistry, MESH: Adenosine/metabolism, MESH: Phosphotransferases (Alcohol Group Acceptor)/antagonists & inhibitors, MESH: Phosphotransferases (Alcohol Group Acceptor)/chemistry, MESH: Phosphotransferases (Alcohol Group Acceptor)/metabolism, MESH: Protein Binding, MESH: Protein Conformation, MESH: Ribose/chemistry, MESH: Staphylococcus aureus/enzymology, MESH: Structure-Activity Relationship, MESH: Adenosine/pharmacology, MESH: Amino Acid Sequence, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Listeria monocytogenes/enzymology, MESH: Molecular Docking Simulation, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27783975; hal-01606966; https://hal.science/hal-01606966Test; PRODINRA: 387353; PUBMED: 27783975; WOS: 000388544600082

الإتاحة: https://doi.org/10.1016/j.ejmech.2016.10.033Test
https://hal.science/hal-01606966Test

المؤلفون: Pfister, Hélène, Paoletti, Julie, Poveda, Ana, Jimenez-Barbero, Jesus, Mulard, Laurence, S

المساهمون: Chimie des Biomolécules - Chemistry of Biomolecules, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Center for Cooperative Research in Biosciences = Centro de Investigación cooperativa en biociencia (Derio, Biscay, Espagne) (CIC bioGUNE), This work has received funding from the Institut Pasteur, the MENESR, France (ENS Cachan, PhD fellowship to H. P.) and the European Commission Seventh Framework Program (FP7/2007–2013) under Grant agreement No. 261472-STOPENTERICS, which included a fellowship to J.P., European Project: 261472,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,STOPENTERICS(2010)

المصدر: ISSN: 0039-7881 ; EISSN: 1437-210X.

مصطلحات موضوعية: amino sugars, glycosylation, oligosaccharide synthesis, shigellosis, vaccine, [CHIM.ORGA]Chemical Sciences/Organic chemistry

العلاقة: info:eu-repo/grantAgreement/EC/FP7/261472/EU/Vaccination against Shigella and ETEC: novel antigens, novel approaches/STOPENTERICS; hal-02916009; https://hal.science/hal-02916009Test

الإتاحة: https://doi.org/10.1055/s-0037-1609719Test
https://hal.science/hal-02916009Test

المؤلفون: Mulard, Laurence, Pfister, Hélène, Paoletti, Julie, Poveda, Ana, Jimenez-Barbero, Jesus

المساهمون: European Commission Seventh Framework Program

المصدر: Synthesis ; volume 50, issue 21, page 4270-4282 ; ISSN 0039-7881 1437-210X

الإتاحة: https://doi.org/10.1055/s-0037-1609719Test

المؤلفون: Pfister, Hélène B., Paoletti, Julie, Poveda, Ana, Jimenez-Barbero, Jesus, Mulard, Laurence A.

المصدر: Synthesis; 2018, Vol. 50 Issue 21, p4270-4282, 13p

مصطلحات موضوعية: SHIGELLOSIS, POLYSACCHARIDES, ZWITTERIONS, DIARRHEA, AMINO sugars

المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie

المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://pasteur.hal.science/pasteur-01483767Test; PUBMED: 25108359

الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://pasteur.hal.science/pasteur-01483767Test

المؤلفون: Castonguay, Annie, Wilson, Eleanor, Al-Hajaj, Noura A., Petitjean, Laurène, Paoletti, Julie, Maysinger, Dusica, Kakkar, Ashok

المصدر: http://pubs.rsc.org/en/content/articlepdf/2011/cc/c1cc15354dTest.

مصطلحات موضوعية: Antioxidants, Azides, Acetylene

العلاقة: Pid: 144879; https://escholarship.mcgill.ca/concern/articles/bv73c4458Test

الإتاحة: https://escholarship.mcgill.ca/concern/articles/bv73c4458Test

المؤلفون: Castonguay, Annie, Wilson, Eleanor, Al-Hajaj, Noura, Petitjean, Laurène, Paoletti, Julie, Maysinger, Dusica, Kakkar, Ashok

المصدر: Chemical Communications; Oct2011, Vol. 47 Issue 44, p12146-12148, 3p

مصطلحات موضوعية: THERMOCHEMISTRY, DENDRIMERS, DRUG delivery systems, TEMPERATURE effect, LIPOIC acid, INFLAMMATION, OXIDATIVE stress