-
1
المؤلفون: Izuki Amano, Megan J. Ritter, Lorraine Soares De Oliveira, Kristen R Vella, Anthony N. Hollenberg, Norihiro Imai
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 53, Iss, Pp 101315-(2021)مصطلحات موضوعية: Male, medicine.medical_specialty, OGTT, oral glucose tolerance test, Retinoic acid, Context (language use), Mice, Transgenic, Biology, chemistry.chemical_compound, Mice, Internal medicine, medicine, Animals, Homeostasis, Nuclear Receptor Co-Repressor 1, EF, ejection fraction, Nuclear Receptor Co-Repressor 2, Gene repression, Molecular Biology, Nuclear receptor co-repressor 1, Mice, Knockout, PTT, pyruvate tolerance test, Cell Biology, TG, triglycerides, HDAC3, RC31-1245, Thyroid hormone, Endocrinology, TH, thyroid hormone, chemistry, Nuclear receptor, Lipogenesis, IPGTT, intraperitoneal glucose tolerance test, Female, Original Article, HPT, hypothalamic pituitary thyroid axis, TSH, thyroid stimulation hormone, Corepressor, Tamoxifen, Nuclear corepressors, TR, thyroid hormone receptor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6076592e9f14dec1f82dc80e3657edcbTest
https://pubmed.ncbi.nlm.nih.gov/34390859Test -
2
المؤلفون: Jing Gao, Takahito Otani, Masato Hirata, Satoru Mukai, Tomoyo Kawakubo-Yasukochi, Ronghao Tang, Akiko Mizokami, Sakura Chishaki, Hiroshi Takeuchi, Eijiro Jimi, Takashi Kanematsu, Tomomi Sano, Miho Matsuda
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, eWAT, epididymal white adipose tissue, obesity, Adipose tissue, Hormone-sensitive lipase, HFS, high-fat and high-sucrose, Biochemistry, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Mice, Adipocyte, Conditional gene knockout, Adipocytes, Insulin, RER, respiratory exchange ratio, GluOC, uncarboxylated form of osteocalcin, Mice, Knockout, NEFA, nonesterified fatty acid, Adipose Tissue, FoxO1, forkhead box O1, GTT, glucose tolerance test, HSL, hormone-sensitive lipase, adipose triglyceride lipase (ATGL), Research Article, medicine.medical_specialty, forkhead box O1 (FoxO1), Lipolysis, Osteocalcin, GPRC6A, adipocyte, 03 medical and health sciences, Internal medicine, 3T3-L1 Cells, medicine, Animals, Humans, db-cAMP, dibutyryl-cAMP, IRF4, interferon regulatory factor 4, Molecular Biology, Inflammation, PTT, pyruvate tolerance test, ATGL, adipose triglyceride lipase, 030102 biochemistry & molecular biology, PKI, protein kinase A inhibitor, Cell Biology, Lipase, Glucose Tolerance Test, 030104 developmental biology, Endocrinology, chemistry, G protein–coupled receptor, Adipose triglyceride lipase, PKA, protein kinase A, Adipocyte hypertrophy, Insulin Resistance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1071bba384b52dd2c1bcbfadb6f1ee23Test
https://pubmed.ncbi.nlm.nih.gov/33428938Test -
3
المؤلفون: Jennifer E. Gallagher, Dorothy Kisielewski, John F. Dillon, Shaun V. Walsh, Diane Cassidy, David J. Harrison, Ritu Sharma, Tadashi Honda, John D. Hayes, Alison D. McNeilly, Michael L.J. Ashford, Albena T. Dinkova-Kostova, Rory J. McCrimmon
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)مصطلحات موضوعية: NQO1, NAD(P)H:quinone oxidoreductase 1, TNF-α, tumor necrosis factor-α, IRE1α, inositol requiring kinase-1α, SCAD, short-chain acyl-CoA dehydrogenase, C/EBP, CCAAT/enhancer-binding protein, PCR, polymerase chain reaction, UPR, unfolded protein response, 0302 clinical medicine, Fibrosis, MGPAT, mitochondrial glycerol-3-phosphate acetyltransferase, ATF4, activating transcription factor-4, DGAT2, diacylglycerol acyltransferase-2, LXRα, liver X receptor α, Glucose homeostasis, eIf2α, eukaryotic translation initiation factor 2A, IKK, IκB kinase, ACOT7, acetyl-CoA thioesterase 7, Original Research, TGFβ, transforming growth factor beta-1, SLC7A11, solute carrier family 7 member 11, GSSG, oxidized glutathione, MTTP, microsomal triglyceride transfer protein, NASH, Gastroenterology, TXN1, thioredoxin-1, 3. Good health, ChREBP, carbohydrate-responsive element-binding protein, 030220 oncology & carcinogenesis, NASH, nonalcoholic steatohepatitis, medicine.medical_specialty, PARP, poly ADP ribose polymerase, qRT-PCR, quantitative reverse transcriptase PCR, GSTM1, glutathione S-transferase Mu-1, GCLC, glutamate-cysteine ligase catalytic, Nrf2, ACACA, acetyl-CoA carboxylase alpha, 03 medical and health sciences, FXR, farnesoid X receptor, Nrf2, NF-E2 p45-related factor 2, COX2, cyclooxygenase-2, Keap1, Kelch-like ECH-associated protein-1, PPARα, peroxisome proliferator-activated receptor α, PTT, pyruvate tolerance test, HMOX1, heme oxygenase-1, RC, regular chow, p58IPK, p58 inhibitor of the PKR kinase, medicine.disease, TBE-31, 030104 developmental biology, Endocrinology, COL1A1, collagen, type I, alpha-1, Unfolded protein response, CAT, catalase, 0301 basic medicine, PDI, protein disulfide isomerase, GSH, reduced glutathione, FASN, fatty acid synthase, BCL-2, B-cell lymphoma, MPO, myeloperoxidase, AP-1, activator protein 1, DMSO, dimethyl sulfoxide, medicine.disease_cause, SHP, small heterodimer partner, CDDO, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid, CHOP, C/EBP homologous protein, TXNRD1, thioredoxin reductase-1, HF30Fr, high-fat diet with 30% fructose in drinking water, IκB, inhibitor of NF-κB, SFN, sulforaphane, ADRP, adipose differentiation-related protein, NAS, NAFLD activity score, GPX2, glutathione peroxidase-2, Chemistry, MCP-1, monocyte chemotactic protein-1, XBP1, X-box binding protein-1, SREBP-1c, sterol regulatory element-binding protein-1c, Lipogenesis, GTT, glucose tolerance test, PERK, PRK-like endoplasmic reticulum kinase, PTGR1, prostaglandin reductase-1, GSTA4, glutathione S-transferase Alpha-4, medicine.symptom, NAFLD, non-alcoholic fatty liver disease, α-SMA, alpha smooth muscle actin, ACOX2, acetyl-CoA oxidase 2, HFFr, high-fat diet with fructose in drinking water, NF-κB, nuclear factor-κB, GCLM, glutamate-cysteine ligase modifier, Inflammation, JNK1, c-Jun N-terminal kinase 1, CD36, cluster of differentiation 36, ER, endoplasmic reticulum, Insulin resistance, HF, high-fat, HF55Fr, high-fat diet with 55% fructose in drinking water, Internal medicine, ATF6, activating transcription factor-6, medicine, ApoB, apolipoprotein B, lcsh:RC799-869, CES1G, carboxylesterase 1g, ITT, insulin tolerance test, MCD, methionine- and choline-deficient, ACLY, ATP citrate lyase, Hepatology, SCD1, stearoyl-CoA desaturase-1, NOS2, nitric oxide synthase-2, PRDX6, peroxiredoxin 6, PPARγ, peroxisome proliferator-activated receptor γ, BIP, binding immunoglobulin protein, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, Steatosis, CPT1A, carnitine palmitoyltransferase 1a, Oxidative stress
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdd8de56b5ba950a8c970d72cce7012Test
https://doi.org/10.1016/j.jcmgh.2017.11.016Test -
4
المؤلفون: Wenhao Ge, Xi Xu, Rui Cheng, Yunxia Yang, Yang Zhao, Dan Weng, Zhao Ding, Jianfa Zhang, Shiming Wang
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, G6PC, Transcription, Genetic, medicine.medical_treatment, FOXO1, cellular methylation potential, Biochemistry, Mice, Mice, Inbred NOD, Adenine nucleotide, Insulin, diabetes, biology, Adenine Nucleotides, Forkhead Box Protein O1, Chemistry, SAM, S-adenosylmethionine, 5′-AMP, Liver, H3K9 methylation, hormones, hormone substitutes, and hormone antagonists, Research Article, AD, actinomycin D, endocrine system, medicine.medical_specialty, FOXO1, forkhead box protein O1, Diabetes Mellitus, Experimental, 03 medical and health sciences, Downregulation and upregulation, Internal medicine, FFA, free fatty acid, medicine, Animals, Humans, Molecular Biology, Transcription factor, PTT, pyruvate tolerance test, 030102 biochemistry & molecular biology, Gluconeogenesis, SAH, S-adenosylhomocysteine, nutritional and metabolic diseases, Promoter, Cell Biology, Insulin receptor, Glucose, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Gene Expression Regulation, Hyperglycemia, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0a51a2b04d95fb5be0ca591b075400Test
https://doi.org/10.1016/j.jbc.2021.100846Test -
5
المؤلفون: Dmitry Akhmedov, Kavitha Rajendran, Nicholas J. Justice, Jingqi Fu, Mark Nixon, Rebecca Berdeaux, Randi Stewart-Fitzgibbon, Micah Gibson, Yisel A. Rivera-Molina, Maria G. Mendoza-Rodriguez, Eric D. Berglund
المصدر: Molecular Metabolism, Vol 5, Iss 1, Pp 34-46 (2016)
Molecular Metabolismمصطلحات موضوعية: 0301 basic medicine, Glucose uptake, FGF21, fibroblast growth factor 21, HDAC, histone deacetylase, Pepck, phosphoenolpyruvate carboxykinase, SIK, salt inducible kinase, GIR, glucose infusion rate, HFD, high fat diet, AMP-activated protein kinase, CRTC, Glucose homeostasis, SIK1, Glucose tolerance test, medicine.diagnostic_test, CREB, FSK, forskolin, Glgn, glucagon, WAT, white adipose tissue, Glut, glucose transporter, cAMP, cyclic adenosine monophosphate, IBMX, 3-isobutyl-1-methylxantine, medicine.anatomical_structure, G6pase, glucose 6-phosphatase, GDR, glucose disposal rate, GTT, glucose tolerance test, Original Article, HSP, heat shock protein, CRTC, CREB regulated transcription coactivator, lcsh:Internal medicine, medicine.medical_specialty, Pgc, peroxisome proliferator-activated receptor gamma coactivator, Biology, FOXO1, forkhead box protein O1, AKT, protein kinase B, 03 medical and health sciences, Insulin resistance, CHX, cycloheximide, Internal medicine, medicine, lcsh:RC31-1245, Molecular Biology, ITT, insulin tolerance test, PTT, pyruvate tolerance test, Gluconeogenesis, Glucose transporter, Skeletal muscle, Cell Biology, medicine.disease, BAT, brown adipose tissue, AMPK, AMP-activated protein kinase, Insulin receptor, 030104 developmental biology, Endocrinology, Salt inducible kinase, biology.protein, CREB, cAMP response element-binding protein, EndoRa, endogenous rate of glucose appearance
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0277d54dcde91a95c0ba4c58a9f35e6Test
https://doi.org/10.1016/j.molmet.2015.10.004Test -
6
المؤلفون: Emilie Blanchet, Albert Giralt, Caroline Bonner, Lluis Fajas, Pierre-Damien Denechaud, Jean-Sébastien Annicotte, Brigitte Delacuisine, Isabel C. Lopez-Mejia, François Pattou
المساهمون: Ctr Integrat Genom, Université de Lausanne, UMR1048, Inst Malad Metab & Cardiovasc, Institut National de la Santé et de la Recherche Médicale (INSERM), Dynamique Musculaire et Métabolisme (DMEM), Institut National de la Recherche Agronomique (INRA)-Université de Montpellier (UM), Recherche translationnelle sur le diabète - U 1190 (RTD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (GI3M), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), ProdInra, Archive Ouverte, Université de Lausanne = University of Lausanne (UNIL), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 (EGENODIA (GI3M)), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Fajas, Lluis, Université de Montpellier (UM)-Institut National de la Recherche Agronomique (INRA), UMR1190, European Genom Inst Diabet, UMR 1190, European Genom Inst Diabet, Génomique Intégrative et Modélisation des Maladies Métaboliques (EGID), Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)
المصدر: Molecular metabolism
Molecular metabolism, Elsevier, 2018, 11, pp.104-112. ⟨10.1016/j.molmet.2018.02.011⟩
Molecular metabolism, 2018, 11, pp.104-112. ⟨10.1016/j.molmet.2018.02.011⟩
Molecular metabolism, vol. 11, pp. 104-112
Molecular Metabolism
Molecular Metabolism (11), 104-112. (2018)
Molecular Metabolism, Vol 11, Iss, Pp 104-112 (2018)مصطلحات موضوعية: 0301 basic medicine, e2f1, Animals, Cells, Cultured, Diabetes Mellitus, Type 2/metabolism, E2F1 Transcription Factor/genetics, E2F1 Transcription Factor/metabolism, Gluconeogenesis, Hep G2 Cells, Humans, Hyperglycemia/metabolism, Liver/metabolism, Mice, Mice, Inbred C57BL, Signal Transduction, Cell cycle regulators, Diabetes, E2F1, Hyperglycemia, Liver metabolism, [SDV]Life Sciences [q-bio], PPARGC1A, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PTT, Pyruvate tolerance test, 0302 clinical medicine, HFD, high fat diet, PCK1, Glucose homeostasis, liver metabolism, Impaired gluconeogenesis, G6PC, glucose-6-phosphatase G6PC, diabetes, cell cycle regulators, CDK4, cyclin–cyclin-dependent kinase 4, 3. Good health, [SDV] Life Sciences [q-bio], Liver, 030220 oncology & carcinogenesis, PCK1, Phosphoenolpyruvate carboxykinase 1, Original Article, biological phenomena, cell phenomena, and immunity, cAMP, Cyclic adenosine monophosphate, lcsh:Internal medicine, medicine.medical_specialty, endocrine system, 03 medical and health sciences, FOXO1, Forkhead box protein O1, Insulin resistance, Internal medicine, Diabetes mellitus, Genetic model, medicine, lcsh:RC31-1245, Molecular Biology, business.industry, Cell Biology, medicine.disease, gluconeogenesis, hyperglycemia, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, CREB, cAMP response element-binding protein, PKA, protein kinase A, Steatosis, business, FAO, fatty acid oxidation, E2F1 Transcription Factor
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07795e75e90e5c1883a9562d0888d260Test
https://hal.archives-ouvertes.fr/hal-01918093/documentTest -
7
المؤلفون: Wee Kiat Ong, Greg C. Smith, Gordon W. Rewcastle, Peter R. Shepherd, Weiping Han, Jackie D. Kendall
المصدر: Biochemical Journal
مصطلحات موضوعية: Male, Pyridines, medicine.medical_treatment, phosphoinositide 3-kinase catalytic α polypeptide (PIK3CA), LC-MS/MS, liquid chromatography tandem MS, Biochemistry, phosphoinositide 3-kinase (PI3K), BMR, basal metabolic rate, Eating, Mice, PI3KCA, PI3K catalytic α polypeptide, Enzyme Inhibitors, media_common, Phosphoinositide-3 Kinase Inhibitors, ATM, ataxia telangiectasia mutated, Sulfonamides, TOR Serine-Threonine Kinases, mammalian target of rapamycin (mTOR), Imidazoles, Isoenzymes, PIKK, phosphoinositide kinase-related kinase, KI, knockin, Quinolines, GTT, glucose tolerance test, PI3K, phosphoinositide 3-kinase, Research Article, Gene isoform, medicine.medical_specialty, insulin, Class I Phosphatidylinositol 3-Kinases, media_common.quotation_subject, glucose metabolism, mTOR, mammalian target of rapamycin, P110α, Biology, Carbohydrate metabolism, Motor Activity, In vivo, Internal medicine, medicine, Animals, Furans, Molecular Biology, PI3K/AKT/mTOR pathway, ITT, insulin tolerance test, PTT, pyruvate tolerance test, KO, knockout, Insulin, Hydrazones, Appetite, Cell Biology, Endocrinology, Glucose, Pyrimidines, P110δ
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820523a0345782a3ea5f0b2738bc7a43Test
http://europepmc.org/articles/PMC3343648Test