المؤلفون: Soo-Yeon Hwang, Seojeong Park, Hyunji Jo, Seung Hee Seo, Kyung-Hwa Jeon, Seojeong Kim, Ah-Reum Jung, Chanju Song, Misun Ahn, Soo Yeon Kwak, Hwa-Jong Lee, Motonari Uesugi, Younghwa Na, Youngjoo Kwon

المصدر: Journal of Advanced Research, Vol 47, Iss , Pp 173-187 (2023)

مصطلحات موضوعية: HER2 transcriptional downregulator, ELF3-MED23 interaction, Small molecule PPI inhibitor, Hotspot identification, Trastuzumab resistance, Medicine (General), R5-920, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2090123222001710Test; https://doaj.org/toc/2090-1232Test

الوصول الحر: https://doaj.org/article/c514c7b5d10c489d80d09349a306cdd7Test

المؤلفون: Yunfeng Sun, Lulu Zheng, Bo Yang, Shuyu Ge, Qiang Li, Mingwan Zhang, Shenghui Shen, Yin Ying

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2575-2588 (2022)

مصطلحات موضوعية: Keap1-Nrf2 PPI inhibitor, drug design, synthesis, inflammatory response, oxidative stress, myocarditis, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1475-6366Test; https://doaj.org/toc/1475-6374Test

الوصول الحر: https://doaj.org/article/a304097335bb496cb73964366656bbbfTest

المؤلفون: Yawei Wang, Binlin Tang, Huijuan Li, Jiancheng Zheng, Can Zhang, Zeyu Yang, Xu Tan, Peng Luo, Le Ma, Yang Wang, Lei Long, Zelin Chen, Zhenliang Xiao, Lijie Ma, Jing Zhou, Yu Wang, Chunmeng Shi

المصدر: EBioMedicine, Vol 90, Iss , Pp 104480- (2023)

مصطلحات موضوعية: Macrophage-targeting therapy, Small-molecule compound, Keap1–Nrf2 PPI inhibitor, Sepsis, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2352396423000452Test; https://doaj.org/toc/2352-3964Test

الوصول الحر: https://doaj.org/article/385cf55e01284d12b22e6d231e76f674Test

المؤلفون: Hao Zhang (15339), Chenglong Liu (317596), Qiushi Chen (765659), Li-An Shen (14380485), Wenting Xiao (14380488), Jiayi Li (329430), Yonghui Wang (287491), Di Zhu (1450108), Qingwei Zhang (23651), Jianqi Li (43568)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Hematology, Infectious Diseases, Virology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, cell lymphoma 9, efficiently enhanced anti, compound selectively inhibited, bcl9 ppi inhibitors, bcl9 ppi inhibitor, 50 , 41 , showed potent anti, β ‑ catenin, k <, , tregs ), single agent, potential strategy, phenylpiperidine derivatives, molecule β

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_Novel_3_Phenylpiperidine_Derivatives_Targeting_the_Catenin_B-Cell_Lymphoma_9_Interaction_as_a_Single_Agent_and_in_Combination_with_the_Anti-PD_1_Antibody_for_the_Treatment_of_Colorectal_Cancer/21865977Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.2c01568.s001Test

المساهمون: Koide, Shohei [Univ. of Chicago, IL (United States); New York Univ. Langone Medical Center, NY (United States)]

المصدر: Journal of Biological Chemistry; 291; 16

وصف الملف: Medium: ED; Size: p. 8836-8847

الوصول الحر: http://www.osti.gov/scitech/servlets/purl/1249239Test

المؤلفون: Qiuyue Zhang, Ling Yan, Yuxuan Zhang, Lixiao Zhang, Jia Yu, Qidong You, Lei Wang

مصطلحات موضوعية: Medicinal and biomolecular chemistry not elsewhere classified, HSP90–CDC37 PPI inhibitor, pseudosubstrate, rational design, sequence alignment

العلاقة: https://figshare.com/articles/dataset/Rational_design_of_peptide_inhibitors_targeting_HSP90_CDC37_protein_protein_interaction/24960429Test

الإتاحة: https://doi.org/10.25402/fmc.24960429.v1Test
https://figshare.com/articles/dataset/Rational_design_of_peptide_inhibitors_targeting_HSP90_CDC37_protein_protein_interaction/24960429Test

المؤلفون: Garcia, Manon, Hoffer, Laurent, Leblanc, Raphaël, Benmansour, Fatiha, Feracci, Mikael, Derviaux, Carine, Egea-Jimenez, Antonio Luis, Roche, Philippe, Zimmermann, Pascale, Morelli, Xavier, Barral, Karine

المساهمون: Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), ANR-11-IDEX-0001,Amidex,INITIATIVE D'EXCELLENCE AIX MARSEILLE UNIVERSITE(2011), ANR-18-CE13-0017,SynTEV,Rôle des réseaux tétraspanines-syndécanes-PDZ dans l'hétérogénéité moléculaire et fonctionelle des vésicules extracellulaires(2018)

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Fragment-based drug design, Small molecule PPI inhibitor, Syntenin-syndecan interaction inhibitors, Exosomes biogenesis, Cancer therapy, [CHIM.CHEM]Chemical Sciences/Cheminformatics, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: hal-03379016; https://hal.science/hal-03379016Test; https://hal.science/hal-03379016/documentTest; https://hal.science/hal-03379016/file/EJMCh_Barral_2021_27052021.pdfTest

الإتاحة: https://doi.org/10.1016/j.ejmech.2021.113601Test
https://hal.science/hal-03379016Test
https://hal.science/hal-03379016/documentTest
https://hal.science/hal-03379016/file/EJMCh_Barral_2021_27052021.pdfTest

المؤلفون: Xavier Guillory (4567150), Inesa Hadrović (11325305), Pim J. de Vink (5867474), Andrea Sowislok (4567144), Luc Brunsveld (540877), Thomas Schrader (1356147), Christian Ottmann (1399450)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Inorganic Chemistry, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, peptidic ligand, Supramolecular Enhancement, supramolecular protein binder, Molecular Dynamics, supramolecular chemical biology concept, binding mode, novel chemical tools, MD, PPI inhibitor, protein affinity, X-ray crystal structure elucidation

العلاقة: https://figshare.com/articles/journal_contribution/Supramolecular_Enhancement_of_a_Natural_14_3_3_Protein_Ligand/16430879Test

الإتاحة: https://doi.org/10.1021/jacs.1c07095.s005Test

المؤلفون: Takatsugu Kosugi (10703213), Masahito Ohue (10699725)

مصطلحات موضوعية: Chemoinformatics, Bioinformatics and Computational Biology, drug discovery, protein-protein interaction (PPI), drug-likeness filter, QED, QEPPI, PPI inhibitor

العلاقة: https://figshare.com/articles/preprint/Quantitative_Estimate_of_Protein-Protein_Interaction_Targeting_Drug-likeness/14489769Test

الإتاحة: https://doi.org/10.26434/chemrxiv.14489769.v1Test

المؤلفون: Sungjae Choi, Jungwoo Park, Jiwon Yeon, Ahjin Jang, Woo Cheol Lee, Yangmee Kim

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 7, p 3317 (2021)

مصطلحات موضوعية: A. baumannii, fatty acid synthesis, acyl carrier protein, KAS III, protein–protein interaction (PPI) inhibitor, NMR spectroscopy, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1422-0067/22/7/3317Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test

الوصول الحر: https://doaj.org/article/d61e2e6432994fa49299f9aa7c13b5afTest