المؤلفون: Miao Zhang, Yongcai Li, Tiaolan Wang, Yang Bi, Rong Li, Yi Huang, Renyan Mao, Qianqian Jiang, Yongxiang Liu, Dov B. Prusky

المصدر: Frontiers in Plant Science, Vol 12 (2021)

مصطلحات موضوعية: Alternaria alternata, PKA protein kinase, pear fruit, wax, hydrophobicity, virulence, Plant culture, SB1-1110

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fpls.2021.642601/fullTest; https://doaj.org/toc/1664-462XTest

الوصول الحر: https://doaj.org/article/9cd4122402124097ae469465ddddd5e5Test

المؤلفون: C. Chris Yun, Yiran Han, Songbai Lin, Peijian He, Kayte A. Jenkin

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 695-716 (2022)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: NEDD4, RC799-869, CTX, cholera toxin, medicine.disease_cause, IEC, intestinal epithelial cell, Enteropathogenic Escherichia coli, Mice, EPEC, enteropathogenic E coli, PCR, polymerase chain reaction, Ubiquitin, Phosphorylation, Ub, ubiquitin, ANOVA, analysis of variance, Original Research, biology, Sodium-Hydrogen Exchanger 3, Chemistry, FSK, forskolin, Cholera toxin, Gastroenterology, Diseases of the digestive system. Gastroenterology, DUB, deubiquitinating enzyme, Ubiquitin ligase, Diarrhea, DRA, down-regulated in adenoma, NHE, Na+/H+ exchanger, Sodium Transporter, hNHE3, human NHE3, sh, short hairpin, medicine.symptom, Cholera Toxin, macromolecular substances, PKC, protein kinase C, medicine, Animals, Humans, CFTR, cystic fibrosis transmembrane conductance regulator, IF, immunofluorescence, Protein kinase A, HBSS, Hank’s balanced saline solution, Hepatology, Sodium, Ubiquitination, Wild type, ENaC, epithelial Na+ channel, WT, wild-type, Molecular biology, pHi, intracellular pH, biology.protein, Nedd4, neural precursor cell expressed, developmentally down-regulated 4, USP, ubiquitin-specific peptidase, PKA, protein kinase A, SD, standard deviation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d39e72e4258b61df22d22d51d780ecTest
https://doi.org/10.1016/j.jcmgh.2021.11.006Test

المؤلفون: Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)

مصطلحات موضوعية: MCOLN1, mucolipin 1, Review, OPTN, optineurin, UPR, unfolded protein response, LIMP1, lysosomal integral membrane protein-1, General Pharmacology, Toxicology and Pharmaceutics, BNIP3L, BCL2 interacting protein 3 like, STBD1, starch-binding domain-containing protein 1, PLIN3, perilipin 3, LIR, LC3 interacting region, PPARα, peroxisomal proliferator-activated receptor-alpha, mTORC1, mammalian target of rapamycin complex 1, Translation (biology), WIPI1, WD repeat domain phosphoinositide-interacting protein 1, TBK1, serine/threonine-protein kinase, Cell biology, GIM, GABARAP-interacting motif, CREB, cAMP response element binding protein, PP2A, protein phosphatase 2a, Liver metabolism, CLN3, lysosomal/endosomal transmembrane protein, LALP70, lysosomal apyrase-like protein of 70 kDa, LD, lipid droplet, RETREG1, reticulophagy regulator 1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, RM1-950, ATL3, Atlastin GTPase 3, RTNL3, a long isoform of RTN3, LAMP2, lysosomal-associated membrane protein-2, FXR, farnesoid X receptor, Farnesoid X receptor, Cryptochrome 1, FFA, free fatty acid, TFEB/TFE3, transcription factor EB, ULK1, Unc-51 like autophagy activating kinase 1, TRAC-1, thyroid-hormone-and retinoic acid-receptor associated co-repressor 1, RTN3, reticulon 3, S6K, P70-S6 kinase, SEC62, SEC62 homolog, preprotein translocation factor, GABARAPL1, GABA type A receptor associated protein like 1, TEX264, testis expressed 264, ER-phagy receptor, DFCP1, double FYVE-containing protein 1, LXRa, liver X receptor a, SLC36A1, solute carrier family 36 member 1, V-ATPase, vacuolar-ATPase, Regeneration (biology), Quality control, AIM, Atf8 interacting motif, VLDL, very-low-density lipoprotein, CYP7A1, cholesterol 7α-hydroxylase, NBR1, BRCA1 gene 1 protein, BCL2L13, BCL2 like 13, TGR5, takeda G protein receptor 5, NCoR1, nuclear receptor co-repressor 1, PKA, protein kinase A, Function (biology), CRY1, cryptochrome 1, LAMP1, lysosomal-associated membrane protein-1, Anabolism, S6RP, S6 ribosomal protein, LIMP3, lysosomal integral membrane protein-3, FAM134B, family with sequence similarity 134, member B, Nutrient regeneration, SPIN, spindling, FOXO1, Forkhead box O1, SCARB2, scavenger receptor class B member 2, PQLC2, PQ-loop protein, SQSTM1, sequestosome 1, CMA, chaperonin mediated autophagy, PLIN2, perilipin 2, PXR, pregnane X receptor, NPC-1, Niemann-Pick disease, type C1, SLC38A9, sodium-coupled neutral amino acid transporter 9, Lysosome, TRPML1, transient receptor potential mucolipin 1, BNIP3, BCL2 interacting protein 3, BA, bile acid, ATM, ATM serine/threonine kinase, CAR, constitutive androstane receptor, MFSD1, major facilitator superfamily domain containing 1, NAFLD, non-alcoholic fatty liver disease, PKB, protein kinase B, VDR, vitamin D3 receptor, SIRT1, sirtuin 1, LYAAT-1, lysosomal amino acid transporter 1, SNAT7, sodium-coupled neutral amino acid transporter 7, Biology, S1PR2, sphingosine-1-phosphate receptor 2, ROS, reactive oxygen species, CYP27A1, sterol 27-hydroxylase, Autophagy, NDP52, calcium-binding and coiled-coil domain-containing protein 2, ATGL, adipose triglyceride lipase, Signaling proteins, Catabolism, FUNDC1, FUN14 domain containing 1, CCPG1, cell cycle progression 1, LAAT-1, lysosomal amino acid transporter 1 homologue, PEX5, peroxisomal biogenesis factor 5, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, SLC38A7, solute carrier family 38 member 7, Therapeutics. Pharmacology, Homeostasis, Drug metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c0ac6db641c550d04c5a5c6ba5a1aTest
https://doi.org/10.1016/j.apsb.2021.07.021Test

المؤلفون: Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro

المصدر: Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: HFD, high-fat diet, Cys, cysteine, cGAS, cyclic GMP–AMP synthase, Review, Poly: I.C, polyinosinic-polycytidylic acid, SAVI, STING-associated vasculopathy with onset in infancy, Bioinformatics, PPI, protein–protein interface, TRAF6, tumor necrosis factor receptor-associated factor 6, TREX1, three prime repair exonuclease 1, STIM1, stromal interaction molecule 1, 0302 clinical medicine, AA, amino acids, GTP, guanosine triphosphate, MLKL, mixed lineage kinase domain-like protein, ICAM-1, intracellular adhesion molecule 1, Medicine, PDE3B/4, phosphodiesterase-3B/4, General Pharmacology, Toxicology and Pharmaceutics, IKK, IκB kinase, NF-κB, nuclear factor-kappa B, cGAMP, 2′,3′-cyclic GMP–AMP, NLRP3, NOD-, LRR- and pyrin domain-containing protein 3, 0303 health sciences, dsDNA, double-stranded DNA, TFAM, mitochondrial transcription factor A, Fatty liver, Damage-associated molecular patterns, IFNIC, interferon-inducible cells, CTD, C-terminal domain, Mitochondria, Crosstalk (biology), Cardiovascular diseases, SNPs, single nucleotide polymorphisms, 030220 oncology & carcinogenesis, Stimulator of interferon genes, AAD, aortic aneurysm and dissection, MI, myocardial infarction, IFNAR, interferon receptors, ER stress, CVDs, cardiovascular diseases, NASH, nonalcoholic steatohepatitis, Intracellular, CDG, c-di-GMP, NTase, nucleotidyltransferase, ATP, adenosine triphosphate, Ser, serine, mTOR, mammalian target of rapamycin, RM1-950, STING, stimulator of interferon genes, hSTING, human stimulator of interferon genes, AKT, protein kinase B, CDNs, cyclic dinucleotides, TLR, Toll-like receptors, ER, endoplasmic reticulum, 03 medical and health sciences, LBD, ligand-binding pocket, ROS, reactive oxygen species, YAP1, Yes-associated protein 1, IFN, interferon, ISGs, IRF-3-dependent interferon-stimulated genes, DAMPs, danger-associated molecular patterns, IFN-I, type 1 interferon, 030304 developmental biology, Inflammation, Ang II, angiotensin II, TNFα, tumor necrosis factor-alpha, business.industry, IRF3, interferon regulatory factor 3, CTT, C-terminal tail, Autophagy, TAK1, transforming growth factor β-activated kinase 1, Metabolic diseases, medicine.disease, HAQ, R71H-G230A-R293Q, IL, interleukin, mtDNA, mitochondrial DNA, AMPK, AMP-activated protein kinase, Sting, Apoptosis, TBK1, TANK-binding kinase 1, CBD, C-binding domain, LPS, lipopolysaccharides, NO2-FA, nitro-fatty acids, PKA, protein kinase A, NAFLD, nonalcoholic fatty liver disease, Therapeutics. Pharmacology, DsbA-L, disulfide-bond A oxidoreductase-like protein, business, Homeostasis, MST1, mammalian Ste20-like kinases 1, TM, transmembrane, STING, cGAS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44Test
http://www.sciencedirect.com/science/article/pii/S2211383521001775Test

المؤلفون: F Al-Zoghaibi, Asma S.A. Alonazi, Asim Azhar, Khaled A. Al-Hosaini

المصدر: Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 6, Pp 539-551 (2021)

مصطلحات موضوعية: 0301 basic medicine, ERK, Extracellular signal-Regulated Kinase, cAMP, cyclic AMP, G protein, CCR, Chemokine Receptor, GLP1R, Glucagon-Like Peptide-1 Receptor, Druggability, Heterodimerization, Pharmaceutical Science, RM1-950, Review, Computational biology, COX, Cyclooxygenase, Biology, GRKs, AC, Adenylyl Cyclase, 03 medical and health sciences, GPCR, 0302 clinical medicine, DAG, Diacylglycerol, Arrestin, PKA, Protein Kinase A, PIP2, Phosphatidylinositol-4,5-bisphosphate, Receptor, Gene, GRKs, G protein-coupled Receptor Kinases, G protein-coupled receptor, Pharmacology, G protein-coupled receptor kinase, NMDA, N-Methyl D-Aspartate, Drugs, Nbs, Nanobodies, MAPK, Mitogen-Activated Protein Kinase, Signaling, 030104 developmental biology, PAR-1, Protease Activated Receptor 1, Therapeutics. Pharmacology, IP3, Inositol 1,4,5-triphosphate, GIP, Gastric Inhibitory Peptide, 030217 neurology & neurosurgery, Function (biology), G proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14339e0def5699befb4d16ab07f7bd41Test
https://doi.org/10.1016/j.jsps.2021.04.015Test

المؤلفون: Xian Zeng, Dianwen Ju, Jiajun Fan, Yichen Wang, Jinghui Zhang, Jingyun Luan, Kai Yin, Mingming Nie

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)

مصطلحات موضوعية: BCL-2, B cell lymphoma 2, G protein coupled receptor kinase 2, HH, Carcinogenesis, Hedgehog, HIF-1α, MDSCs, myeloid-derived suppressor cells, STAT3, signal transducer and activator of transcription 3, FOLFOX, oxaliplatin, Review, medicine.disease_cause, SMO, Smoothened, Immune tolerance, 0302 clinical medicine, βArr2, β-arrestin2, ATO, arsenic trioxide, hypoxia-inducible factor 1α, IFN-γ: interferon-γ, Medicine, General Pharmacology, Toxicology and Pharmaceutics, TGF-β, transforming growth factor β, 0303 health sciences, glioma-associated oncogene homologue, GRK2, Cancer stem cells, 5-Fu, 5-fluorouracil, TME, tumor microenvironment, IHH, Indian Hedgehog, VEGF, vascular endothelial growth factor, SHH, Sonic Hedgehog, Hedgehog signaling pathway, PD-L1, programmed cell death ligand-1, Tumor microenvironment, 030220 oncology & carcinogenesis, BMI-1, B cell-specific moloney murine leukemia virus insertion region-1, SUFU, Suppressor of Fused, Signal transduction, DHH, Desert Hedgehog, NK, natural killer, CSCs, cancer stem cells, and leucovorin, GLI, NOX4, NADPH Oxidase 4, ALK5, TGF-β receptor I kinase, PTCH, Patched, SNF5, sucrose non-fermenting 5, Gastrointestinal cancer, 03 medical and health sciences, ROS, reactive oxygen species, Immune system, Cancer stem cell, BCC, basal cell carcinoma, 030304 developmental biology, EGF, epidermal growth factor, IL-10/6, interleukin 10/6, ITCH, itchy E3 ubiquitin ligase, ch5E1, chimeric monoclonal antibody 5E1, business.industry, lcsh:RM1-950, WNT, Wingless/Integrated, PD-1, programmed cell death-1, SMAD3, mothers against decapentaplegic homolog 3, medicine.disease, lcsh:Therapeutics. Pharmacology, Drug resistance, Cancer research, PKA, protein kinase A, TAMs, tumor-related macrophages, sense organs, business, Hedgehog, CAFs, cancer-associated fibroblasts

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9591fe5f71a6d93ff75c586983adcbTest
https://doi.org/10.1016/j.apsb.2020.10.022Test

المؤلفون: Yatrik M. Shah, Shogo Takahashi, Sadeesh K. Ramakrishnan, Raja Gopal Reddy Mooli, Frank J. Gonzalez, Sumeet Solanki, Jessica Rodriguez

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 585-597 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, HFD, high-fat diet, Fgf21, fibroblast growth factor 21, β-Oxidation, RC799-869, VHL, Von Hippel-Lindau, PPARα, Liver disease, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Cyp4a10 and Cyp4a14, cytochrome P450, family 4, subfamily a, polypeptide 10 and 14, Nonalcoholic fatty liver disease, Hypoxia, Cells, Cultured, Original Research, Mice, Knockout, chemistry.chemical_classification, Chemistry, Fatty Acids, Fatty liver, Gastroenterology, Diseases of the digestive system. Gastroenterology, Postprandial Period, MEK, ERK, medicine.anatomical_structure, Liver, CD36, cluster of differenatiation 36, Hepatocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, Oxidation-Reduction, medicine.medical_specialty, MAP Kinase Signaling System, Acot1, acyl-CoA thioesterase 1, PPARα, peroxisome proliferator activated receptor alpha, HIF1α and HIF2α, hypoxia inducing factor 1 and 2 alpha, 03 medical and health sciences, Internal medicine, Genetic model, Autophagy, medicine, Animals, HIF, PPAR alpha, RNA, Messenger, Mitogen-Activated Protein Kinase Kinases, Hepatology, Cpt1a, carnitine palmitoyltransferase 1, Fatty acid, Acox1, acyl-coenzyme A oxidase, Feeding Behavior, Lipid Metabolism, medicine.disease, WT, wild-type, Cyclic AMP-Dependent Protein Kinases, Fatty Liver, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Hepatocytes, PKA, protein kinase A, NAFLD, nonalcoholic fatty liver disease, Steatosis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8ab9d3e6c8736a8ba6e7154654a18Test
https://doi.org/10.1016/j.jcmgh.2021.03.011Test

المؤلفون: Maya Finkel, Nufar Buchshtab, Meirav Bar-Shimon, Noga Korenfeld, Ido Goldstein, Meital Charni-Natan

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1021-1036 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, RC799-869, AOA, aminooxyacetate, gluc, glucagon, Mice, Endocrinology, 0302 clinical medicine, Glucocorticoid receptor, Insulin, Glucose homeostasis, Amino Acids, Cells, Cultured, Original Research, biology, Chemistry, Gastroenterology, Fasting, Diseases of the digestive system. Gastroenterology, CREB-Binding Protein, FGF19, fibroblast growth factor 19, Chromatin, TF, transcriptional factor, cAMP, cyclic adenosine monophosphate, ChIP, chromatin immunoprecipitation, Enhancer Elements, Genetic, nt, non-treated, Models, Animal, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, CAMP Responsive Element Binding Protein, medicine.medical_specialty, CREB, cAMP responsive element binding protein, SDS, sodium dodecyl sulfate, Primary Cell Culture, PBS, phosphate-buffered saline, CREB, Glucagon, 03 medical and health sciences, Receptors, Glucocorticoid, cort, corticosterone, Internal medicine, Enhancers, medicine, Animals, AA, amino acid, Glucocorticoids, GR, glucocorticoid receptor, Hepatology, Sequence Analysis, RNA, Catabolism, Gene Expression Profiling, Gluconeogenesis, GRE, glucocorticoid receptor element, CRE, cAMP responsive element, Metabolism, FC, fold change, Fibroblast Growth Factors, SI, synergy index, 030104 developmental biology, Gene Expression Regulation, Hepatocytes, biology.protein, PKA, protein kinase A, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae2cd9101a9b091bf3a2c1fa8f4cfbfTest
https://doi.org/10.1016/j.jcmgh.2021.04.017Test

المؤلفون: Özlem Günay-Esiyok, Nicolas Liem, Kim Chi Vo, Nishith Gupta

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3861-3876 (2020)

مصطلحات موضوعية: PDE, phosphodiesterase, AC, adenylate cyclase, COS, crossover sequence, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, QMEAN, Quality Model Energy Analysis, MOI, multiplicity of infection, smHA, spaghetti monster-HA, cAMP and cGMP signaling, 3′IT, 3′-insertional tagging, 0303 health sciences, Lytic cycle, OCRE, octamer repeat, Phosphodiesterase, Computer Science Applications, Cell biology, HFF, human foreskin fibroblast, HXGPRT, hypoxanthine-xanthine-guanine phosphoribosyltransferase, CRISPR, clustered regularly interspaced short palindromic repeats, 030220 oncology & carcinogenesis, PM, plasma membrane, GC, guanylate cyclase, Biotechnology, Research Article, Bradyzoite, lcsh:Biotechnology, Biophysics, Mutagenesis (molecular biology technique), Biology, Apicomplexa, 03 medical and health sciences, Cyclic nucleotide, lcsh:TP248.13-248.65, GMQE, Global Model Quality Estimation, Genetics, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, FPKM, fragments per kilobase of exon model per million, Tachyzoite, EES, entero-epithelial stages, Intracellular parasite, sgRNA, single guide RNA, Toxoplasma gondii, Subcellular localization, biology.organism_classification, chemistry, IMC, inner membrane complex, MAEBL, merozoite adhesive erythrocytic binding ligand, PKG, protein kinase G, PKA, protein kinase A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952729672d93971172ad6bb332f7a8efTest
http://europepmc.org/articles/PMC7720076Test

المؤلفون: Saeedah Hamdan Al-Jadani, Saad Saeed Alamri, Hani Alothaid, Jehan S. Alrahimi, Mohammed S. Aldughaim

المصدر: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 1, Pp 116-124 (2021)

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Phosphatase, Review, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, ROS, reactive oxygen species, Cell secretion, CREB, cAMP-responsive element-binding protein, Cyclic adenosine monophosphate, Secretion, lcsh:QH301-705.5, Cn, calcineurin, Kinase, PP, protein phosphatase, Protein phosphatase 2, RyR, ryanodine receptor, cAMP signaling, PP2B, Cell biology, Calcineurin, cAMP, cyclic adenosine monophosphate, Intercellular communication, NFAT, nuclear factor of activated T-cells, 030104 developmental biology, chemistry, lcsh:Biology (General), Phosphorylation, Protein kinases/phosphatases, PKA, protein kinase A, General Agricultural and Biological Sciences, Intracellular, 010606 plant biology & botany

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bd077992989fe7b70db57b5b7a848aTest
http://europepmc.org/articles/PMC7783665Test