المؤلفون: Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)

مصطلحات موضوعية: MCOLN1, mucolipin 1, Review, OPTN, optineurin, UPR, unfolded protein response, LIMP1, lysosomal integral membrane protein-1, General Pharmacology, Toxicology and Pharmaceutics, BNIP3L, BCL2 interacting protein 3 like, STBD1, starch-binding domain-containing protein 1, PLIN3, perilipin 3, LIR, LC3 interacting region, PPARα, peroxisomal proliferator-activated receptor-alpha, mTORC1, mammalian target of rapamycin complex 1, Translation (biology), WIPI1, WD repeat domain phosphoinositide-interacting protein 1, TBK1, serine/threonine-protein kinase, Cell biology, GIM, GABARAP-interacting motif, CREB, cAMP response element binding protein, PP2A, protein phosphatase 2a, Liver metabolism, CLN3, lysosomal/endosomal transmembrane protein, LALP70, lysosomal apyrase-like protein of 70 kDa, LD, lipid droplet, RETREG1, reticulophagy regulator 1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, RM1-950, ATL3, Atlastin GTPase 3, RTNL3, a long isoform of RTN3, LAMP2, lysosomal-associated membrane protein-2, FXR, farnesoid X receptor, Farnesoid X receptor, Cryptochrome 1, FFA, free fatty acid, TFEB/TFE3, transcription factor EB, ULK1, Unc-51 like autophagy activating kinase 1, TRAC-1, thyroid-hormone-and retinoic acid-receptor associated co-repressor 1, RTN3, reticulon 3, S6K, P70-S6 kinase, SEC62, SEC62 homolog, preprotein translocation factor, GABARAPL1, GABA type A receptor associated protein like 1, TEX264, testis expressed 264, ER-phagy receptor, DFCP1, double FYVE-containing protein 1, LXRa, liver X receptor a, SLC36A1, solute carrier family 36 member 1, V-ATPase, vacuolar-ATPase, Regeneration (biology), Quality control, AIM, Atf8 interacting motif, VLDL, very-low-density lipoprotein, CYP7A1, cholesterol 7α-hydroxylase, NBR1, BRCA1 gene 1 protein, BCL2L13, BCL2 like 13, TGR5, takeda G protein receptor 5, NCoR1, nuclear receptor co-repressor 1, PKA, protein kinase A, Function (biology), CRY1, cryptochrome 1, LAMP1, lysosomal-associated membrane protein-1, Anabolism, S6RP, S6 ribosomal protein, LIMP3, lysosomal integral membrane protein-3, FAM134B, family with sequence similarity 134, member B, Nutrient regeneration, SPIN, spindling, FOXO1, Forkhead box O1, SCARB2, scavenger receptor class B member 2, PQLC2, PQ-loop protein, SQSTM1, sequestosome 1, CMA, chaperonin mediated autophagy, PLIN2, perilipin 2, PXR, pregnane X receptor, NPC-1, Niemann-Pick disease, type C1, SLC38A9, sodium-coupled neutral amino acid transporter 9, Lysosome, TRPML1, transient receptor potential mucolipin 1, BNIP3, BCL2 interacting protein 3, BA, bile acid, ATM, ATM serine/threonine kinase, CAR, constitutive androstane receptor, MFSD1, major facilitator superfamily domain containing 1, NAFLD, non-alcoholic fatty liver disease, PKB, protein kinase B, VDR, vitamin D3 receptor, SIRT1, sirtuin 1, LYAAT-1, lysosomal amino acid transporter 1, SNAT7, sodium-coupled neutral amino acid transporter 7, Biology, S1PR2, sphingosine-1-phosphate receptor 2, ROS, reactive oxygen species, CYP27A1, sterol 27-hydroxylase, Autophagy, NDP52, calcium-binding and coiled-coil domain-containing protein 2, ATGL, adipose triglyceride lipase, Signaling proteins, Catabolism, FUNDC1, FUN14 domain containing 1, CCPG1, cell cycle progression 1, LAAT-1, lysosomal amino acid transporter 1 homologue, PEX5, peroxisomal biogenesis factor 5, PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase, SLC38A7, solute carrier family 38 member 7, Therapeutics. Pharmacology, Homeostasis, Drug metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c0ac6db641c550d04c5a5c6ba5a1aTest
https://doi.org/10.1016/j.apsb.2021.07.021Test

المؤلفون: Milana Fraiberg, Boris Macek, Zvulun Elazar, Philipp J. Kahle, Anna Lechado Terradas, Katharina Zittlau

المصدر: The Journal of Biological Chemistry
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339

مصطلحات موضوعية: Mitochondrial fission factor, PTM, post-translational modification, Mitochondrial Turnover, MIM, mitochondrial inner membrane, NGLY1, N-glycanase 1, LIR, LC3-interacting region, BNIP, Bcl-2 19 kDa protein-interacting protein, Biochemistry, PD, Parkinson's disease, Mitochondrial Dynamics, DNM1L, FUNDC1, FUN14 domain-containing protein 1, USP, ubiquitin-specific protease, VPS, vacuolar sorting protein, Mitophagy, MFF, mitochondrial fission factor, TFEB, transcription factor EB, MFN, mitofusin, PARL, presenilin-associated rhomboid-like protease, HK2, hexokinase 2, OMA1, overlapping with the mitochondrial matrix ATPase associated with diverse cellular activities (m-AAA) protease 1, Chemistry, phosphorylation, SUMO, small ubiquitin-related modifier, DFCP1, double FYVE domain-containing protein 1, NBR1, next to breast cancer type 1 susceptibility gene 1 protein, DRP1, dynamin-related protein 1, Far, factor arrest, RAB, Ras-associated binding protein, MIRO, mitochondrial Rho GTPase, GCN5L1, general control of amino acid synthesis protein 5-like 1, Cell biology, BAK, Bcl-2 homologous antagonist/killer, Mitochondria, mitochondria, OPA1, optic atrophy protein 1, ddc:540, ARIH1, ariadne-1 homolog in humans, SIRT, sirtuin, Mitochondrial fission, genetics [Mitochondrial Proteins], Signal Transduction, FIS1, autophagy, WIPI, WD40 repeat protein interacting with phosphoinositides, Bcl, B cell lymphoma, TBK1, tumor necrosis factor receptor-associated factor family member associated NF-κB activator-binding kinase 1, NF-κB, nuclear factor-κB, PINK1, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, mTOR, mammalian target of rapamycin, metabolism [Mitochondrial Proteins], CCCP, carbonyl cyanide m-chlorophenyl hydrazone, RING, really interesting new gene, Mitochondrial Proteins, SNARE, soluble N-ethylmaleimide-sensitive factor-attachment protein receptor, ΔΨm, mitochondrial membrane potential, LC3, microtubule-associated protein light chain 3, FKBP8, FK506-binding protein 8, GABARAP, γ-amino-butyric acid receptor-associated protein, MOM, mitochondrial outer membrane, Animals, HOPS, homotypic fusion and protein sorting, ubiquitylation, ATG, autophagy-related protein, FIS1, mitochondrial fission 1 protein, Molecular Biology, gp78, glycoprotein 78, CLEAR, coordinated lysosomal expression and regulation, MGRN1, mahogunin RING finger protein 1, ULK1, uncoordinated protein 51-like kinase 1, protein kinase PINK1, JBC Reviews, BH3, Bcl-2 homology 3 domain, Ubiquitination, AMBRA1, activating molecule in beclin-1 regulated autophagy protein 1, VDAC, voltage-dependent anion selective channel, Cell Biology, metabolism [Mitochondria], HUWE1, homologous to the E6-AP carboxyl terminus (HECT), ubiquitin-associated and WWE domain-containing protein 1, FIP200, focal adhesion kinase-interacting protein of 200 kDa, BAD, Bcl-2 associated agonist of cell death, DUB, deubiquitylating enzyme, Mcl-1, induced myeloid leukemia cell differentiation protein, AMPK, AMP-activated protein kinase, PI3P, phosphatidylinositol 3-phosphate, MUL1, genetics [Mitochondria], TOM, translocase of the outer membrane, mTORC1, mTOR complex 1, Ubl, ubiquitin-like domain, MTS, mitochondrial targeting sequence, MITOL, mitochondrial ubiquitin ligase, ubiquitin ligase parkin, MUL1, mitochondrial ubiquitin ligase 1, NDP52, nuclear dot protein of 52 kDa

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbec8d603702bfc18179f4f97b4c81bTest
http://europepmc.org/articles/PMC8591368Test

المؤلفون: Shue-Fen Luo, Jenn-Haung Lai, Ling-Jun Ho

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: 0301 basic medicine, PRR, pattern recognition receptor, DENV, dengue virus, cGAS, cyclic GMP–AMP synthase, Mitochondrion, Mitochondrial Dynamics, Biochemistry, NLR, NOD-like receptor, Mfn, mitofusin, Mitophagy, TRAF, TNF receptor-associated factor, RIPK2, cytosolic receptor interacting serine/threonine kinase 2, SARS-CoV, severe acute respiratory syndrome-coronavirus, NLRP3, NOD-, LRR- and pyrin domain-containing 3, Mitochondria, Virus, Cell biology, CLR, C-type lectin receptor, TNFα, tumor necrosis factor α, OPA1, optic atrophy 1, Virus Diseases, CARD, caspase activation and recruitment domain, HCV, hepatitis C virus, MAVS, mitochondrial antiviral signaling protein, HPIV3, human parainfluenza virus type 3, PAMP, pathogen-associated molecular pattern, DAMP, danger-associated molecular pattern, Mitochondrial DNA, JEV, Japanese encephalitis virus, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, STING, stimulator of interferon genes, Biology, Antiviral Agents, Article, 03 medical and health sciences, NF-κB, nuclear factor-kappaB, ROS, reactive oxygen species, Immune system, ORF, open reading frame, Downregulation and upregulation, Immunity, KSHV, kaposi’s sarcoma-associated herpesvirus, Animals, Humans, IFN, interferon, TLR, toll-like receptor, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, Immunity, Innate, RLR, retinoic acid-inducible gene 1-like receptor, mtDNA, mitochondrial DNA, vMIA, viral mitochondrion-localized inhibitor of apoptosis, Immune, RIG-I, retinoic acid-inducible gene 1, Drp 1, dynamin-related protein 1, 030104 developmental biology, Apoptosis, CO, cytochrome C oxidase, RSV, respiratory syncytial virus, Therapy, MAPK, mitogen-activated protein kinase, IRF, interferon regulatory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddc4d9d42601f3845bf94ae189aa4cbTest
https://doi.org/10.1016/j.bcp.2018.08.044Test

المؤلفون: Yssa Ann Rodriguez, Partha Krishnamurthy, Xiaojuan Chao, Shaogui Wang, Hemantkumar Chavan, Hartmut Jaeschke, Hua Wang, Xiaowen Ma, De-Xiang Xu, Wen-Xing Ding, Rick T. Dobrowsky, Hong-Min Ni

المصدر: Redox Biology, Vol 22, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: Male, DKO, double knockout, 0301 basic medicine, Clinical Biochemistry, Mitochondria, Liver, Mitochondrion, Biochemistry, Parkin, LC3, microtubule-associated light chain 3, Mice, Cyp2e1, cytochrome P450 2E1, 0302 clinical medicine, Mitophagy, GSH, glutathione, OCR, oxygen consumption rate, Inner mitochondrial membrane, lcsh:QH301-705.5, Mice, Knockout, Liver injury, lcsh:R5-920, Chemistry, digestive, oral, and skin physiology, Glutathione, Mitochondria, 3. Good health, medicine.anatomical_structure, Hepatocyte, VDAC, voltage-dependent anion channel, APAP-DA, APAP-protein adducts, Chemical and Drug Induced Liver Injury, Drug, lcsh:Medicine (General), Research Paper, Cell death, Programmed cell death, WT, Wild-type, Ubiquitin-Protein Ligases, APAP, acetaminophen, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, PINK1, Models, Biological, 03 medical and health sciences, ALT, alanine aminotransferase, Autophagy, medicine, Animals, KO, knockout, Hepatotoxicity, Organic Chemistry, JNK Mitogen-Activated Protein Kinases, medicine.disease, Molecular biology, nervous system diseases, Disease Models, Animal, 030104 developmental biology, lcsh:Biology (General), Hepatocytes, H&E, hematoxylin and eosin, JNK, c-jun N-terminal kinase, NAPQI, N-acetyl-p-benzoquinone imine, Protein Kinases, TUNEL, terminal dUTP nick-end labeling, Biomarkers, Gene Deletion, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c7de0a18b72de1f8a53d8a69cc60ceTest
http://www.sciencedirect.com/science/article/pii/S2213231718312291Test