المؤلفون: Yadav, Sudhanshu, Garrido, Antonio, Hernández, M. Carmen, Oliveros, Juan C., Pérez-García, Vicente, Fraga, Mario F., Carrera, Ana C.

المساهمون: Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Comunidad de Madrid, Asociación Española Contra el Cáncer

مصطلحات موضوعية: PI3Kβ, EZH2, β-catenin, Human stem cells, Stemness, Epigenetics, Primitive streak, Clinical hESC differentiation for regeneration medicine, Stemness/differentiation transition, Polycomb repression release

وصف الملف: application/pdf

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO//SAF2016-79195-R; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-106937RB-I00/ES/HIF2 & NFE2L2, UNA APROXIMACION RACIONAL Y OTRA IMPARCIAL PARA EL TRATAMIENTO DEL CANCER/; S2017/BMD-3804MITIC-CM; info:eu-repo/grantAgreement/AEI//RYC-2019-026956; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-114459RA-I00/ES/DESCIFRANDO LOS MECANISMOS MOLECULARES REGULADOS POR EL COMPLEJO BAP1 PR-DUB DE INVASION CELULAR COMPARTIDOS ENTRE EL TROFOBLASTO HUMANO Y LAS CELULAS CANCEROSAS/; Publisher's version; http://dx.doi.org/10.1016/j.stemcr.2022.09.003Test; Sí; e-issn: 2213-6711; Stem Cell Reports 17(10): 2239-2255 (2022); http://hdl.handle.net/10261/306802Test

الإتاحة: https://doi.org/10.1016/j.stemcr.2022.09.003Test
http://hdl.handle.net/10261/306802Test

المؤلفون: Can Wang, Yangyang Cheng, Yuanhui Zhang, Hongtao Jin, Zengyan Zuo, Aiping Wang, Jianmei Huang, Jiandong Jiang, Weijia Kong

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: berberine, berberrubine, platelet activation, class I PI3Kβ, thrombus formation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2021.734603/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/cc9ea5d5c930474fb34bf6e47fb84b8aTest

المؤلفون: Sudhanshu Yadav, Antonio Garrido, M. Carmen Hernández, Juan C. Oliveros, Vicente Pérez-García, Mario F. Fraga, Ana C. Carrera

المساهمون: Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Comunidad de Madrid, Asociación Española Contra el Cáncer

المصدر: WOS:000873961800006

مصطلحات موضوعية: JNK Mitogen-Activated Protein Kinases, Clinical hESC differentiation for regeneration medicine, Gene Expression, Cell Differentiation, Human stem cells, Cell Biology, β-catenin, Biochemistry, PI3Kβ, Phosphatidylinositol 3-Kinases, Polycomb repression release, Genetics, Humans, Enhancer of Zeste Homolog 2 Protein, Epigenetics, EZH2, Stemness, Embryonic Stem Cells, beta Catenin, Primitive streak, Stemness/differentiation transition, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9400f3d6d98f1847f0b08afca8e3d6fTest
https://doi.org/10.1016/j.stemcr.2022.09.003Test

المؤلفون: Chen, X, Zhabyeyev, P, Azad, AK, Wang, W, Minerath, RA, DesAulniers, J, Grueter, CE, Murray, AG, Kassiri, Z, Vanhaesebroeck, B, Oudit, GY

المصدر: Cardiovascular Research , 115 (8) pp. 1343-1356. (2019)

مصطلحات موضوعية: Myocardial infarction, PI3Kβ, Remodeling, Angiogenesis, Cardiomyocyte death

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10063314/1/2018-Cardiovascular%20Research-CVR2018721-PI3Kbeta%20in%20postMI%20cardiac%20remodeling.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10063314Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10063314/1/2018-Cardiovascular%20Research-CVR2018721-PI3Kbeta%20in%20postMI%20cardiac%20remodeling.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10063314Test/

المؤلفون: Michelle Miller, Philip Thompson, Sandra Gabelli

المصدر: Biomolecules; Volume 9; Issue 3; Pages: 82

مصطلحات موضوعية: PIK3CA, isoform selectivity, p110, p85, phosphatidylinositol 3-kinase, PI3Kβ, PI3Kα, PI3Kγ, PI3Kδ

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: https://dx.doi.org/10.3390/biom9030082Test

الإتاحة: https://doi.org/10.3390/biom9030082Test

المؤلفون: Shuang Cao, Ruiyuan Cao, Xialing Liu, Xiang Luo, Wu Zhong

المصدر: Molecules; Volume 21; Issue 7; Pages: 876

مصطلحات موضوعية: PI3Kβ, mTOR, kinase inhibitor, docking

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules21070876Test

الإتاحة: https://doi.org/10.3390/molecules21070876Test

المؤلفون: Argun Akcakanat, Filip Janku, Kurt W. Evans, Erkan Yuca, Ming Zhao, Ecaterina Ileana Dumbrava, Funda Meric-Bernstam, Nicci Owusu-Brackett

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, AZD8186, chemotherapy, PI3Kβ, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, medicine, PTEN, Viability assay, PTEN loss, Chemotherapy, biology, Cell growth, Immunotherapy, 3. Good health, 030104 developmental biology, Oncology, Paclitaxel, chemistry, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, biology.protein, immunotherapy, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fec5479c8eaf66a87957e625118993Test
https://doi.org/10.18632/oncotarget.27503Test

المؤلفون: Can Wang (157994), Yangyang Cheng (1452571), Yuanhui Zhang (766456), Hongtao Jin (5639756), Zengyan Zuo (11537074), Aiping Wang (532946), Jianmei Huang (5180282), Jiandong Jiang (429653), Weijia Kong (423645)

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, berberine, berberrubine, platelet activation, class I PI3Kβ, thrombus formation

العلاقة: https://figshare.com/articles/dataset/Table1_Berberine_and_Its_Main_Metabolite_Berberrubine_Inhibit_Platelet_Activation_Through_Suppressing_the_Class_I_PI3K_Rasa3_Rap1_Pathway_docx/16767910Test

الإتاحة: https://doi.org/10.3389/fphar.2021.734603.s001Test

المؤلفون: Sandra B. Gabelli, Michelle S. Miller, Philip E. Thompson

المصدر: Biomolecules, Vol 9, Iss 3, p 82 (2019)
Biomolecules

مصطلحات موضوعية: Gene isoform, Models, Molecular, PI3Kα, Indazoles, phosphatidylinositol 3-kinase, Chemistry, Pharmaceutical, lcsh:QR1-502, PI3K binding, Computational biology, Review, Biochemistry, PI3Kδ, PI3Kγ, lcsh:Microbiology, PI3Kβ, 03 medical and health sciences, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, Structure-Activity Relationship, 0302 clinical medicine, Immune Diseases, Humans, Phosphatidylinositol, Molecular Biology, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, 030304 developmental biology, Phosphoinositide-3 Kinase Inhibitors, 0303 health sciences, Sulfonamides, p85, Molecular Structure, PIK3CA, p110, 3. Good health, Isoenzymes, Structural biology, chemistry, 030220 oncology & carcinogenesis, Selectivity, isoform selectivity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2abb141c68b27df7159e46d00757bfTest
https://www.mdpi.com/2218-273X/9/3/82Test

المؤلفون: Sadiq, Barzan A.

مصطلحات موضوعية: PI3Kα, PTEN, Bitplane Imaris, mouse embryonic fibroblasts, A dissection of class I phosphoinositide 3-kinase signalling in mouse embryonic fibroblasts and prostate organoids, TIRF, phosphoinositide 3-kinase signalling, prostate organoids, PI3Kδ, PI3Kγ, PI3Kβ, Therapeutic interventions, PI3K nuclear localisation, pH and Tumour microenvironment, Widefield, Biotinylation, Lipid signalling, Acidic extracellular microenvironment and cancer, Phospholipid signalling, MEF, Tumour microenvironment, Microscopy, Prostate cancer, MS Lipidomics, phosphoinositide 3-kinase, PI(45)P2, PTEN-null, Confocal, Lipidomics, Effects of pH on class I PI3K signalling, Avi-Tag, PI(34)P2, Streptavidin, PI3K/Akt signalling pathway, AviTag, Imaris, Class I PI3K, PI(345)P3, PI3K/PKB signalling pathway

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f0281f354005bae2cf21b1b7efc2d48dTest