المؤلفون: Janku, Filip, Choong, Grace M, Opyrchal, Mateusz, Dowlati, Afshin, Hierro, Cinta, Rodon, Jordi, Wicki, Andreas, Forster, Martin D, Blagden, Sarah P, Yin, Jun, Reid, Joel M, Muller, Helene, Cmiljanovic, Natasa, Cmiljanovic, Vladimir, Adjei, Alex A

المصدر: Cancers , 16 (6) , Article 1137. (2024)

مصطلحات موضوعية: PI3K/mTOR inhibitor, clinical trial, solid tumor, safety, intermittent dosing schedule

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10190777/1/cancers-16-01137-v3.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10190777Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10190777/1/cancers-16-01137-v3.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10190777Test/

المؤلفون: Filip Janku, Grace M. Choong, Mateusz Opyrchal, Afshin Dowlati, Cinta Hierro, Jordi Rodon, Andreas Wicki, Martin D. Forster, Sarah P. Blagden, Jun Yin, Joel M. Reid, Helene Muller, Natasa Cmiljanovic, Vladimir Cmiljanovic, Alex A. Adjei

المصدر: Cancers, Vol 16, Iss 6, p 1137 (2024)

مصطلحات موضوعية: PI3K/mTOR inhibitor, clinical trial, solid tumor, safety, intermittent dosing schedule, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/16/6/1137Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/dc11e6bb219149eea8c74e000a1fc021Test

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi‑Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

المساهمون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jone, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi‑Sharifi, Eneda Toska, Matthew S. David, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: PI3K/AKT/mTORC pathway, Pan PI3K inhibitor, Isoform-specific PI3K inhibitor, Dual PI3K/mTOR inhibitor, AKT inhibitor, Allosteric mTOR inhibitor, ATP-competitive mTOR inhibitor, Bi-steric mTOR inhibitor, PDK1 inhibitor, Cancer

العلاقة: volume:22; issue:1; numberofpages:37; journal:MOLECULAR CANCER; https://hdl.handle.net/10447/604813Test

الإتاحة: https://doi.org/10.1186/s12943-023-01827-6Test
https://hdl.handle.net/10447/604813Test

المؤلفون: Shan Xu, Xin Sun, Leixuan Luo, Yang Yang, Qiuyan Guo, Sheng Tang, Zhiyan Jiang, Yuzhen Li, Jiaqian Han, Wenhui Gan, Feiyi Yang, Xuan Zhang, Yijun Liu, Chuanchuan Sun, Jie He, Meng Liu, Daiying Zuo, Wufu Zhu, Yingliang Wu

المصدر: Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113537- (2022)

مصطلحات موضوعية: Breast cancer, TNBC, PI3K/mTOR inhibitor, XS-2, In vitro and in vivo antitumor activity, Antitumor mechanism, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S075333222200926XTest; https://doaj.org/toc/0753-3322Test

الوصول الحر: https://doaj.org/article/fefec4ccb42946699ef2c27b7c718346Test

المؤلفون: Shaheenah Dawood, Maria Konstantionva, Rebecca Dent, Florencia Perazzo, Sung-Bae Kim, Cynthia Villarreal-Garza, Sandra Franco, Ming-Shen Dai, Sergio Simon

المصدر: BMC Proceedings, Vol 15, Iss S10, Pp 1-17 (2021)

مصطلحات موضوعية: Cyclin-dependent kinase 4/6 inhibitor, Endocrine therapy, Hormone receptor-positive, Human epidermal growth factor receptor 2 negative, Metastatic breast cancer PI3K/mTOR inhibitor, Registry, Medicine, Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1753-6561Test

الوصول الحر: https://doaj.org/article/0462d2991d9442d385c3dd5b25517b3aTest

المؤلفون: Yang H, Jing H, Han X, Tan H, Cheng W

المصدر: Drug Design, Development and Therapy, Vol Volume 15, Pp 531-542 (2021)

مصطلحات موضوعية: minimally invasive cancer treatment strategy, sonosensitizer, pi3k/mtor inhibitor, ir820 nanobubbles, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/synergistic-anticancer-strategy-of-sonodynamic-therapy-combined-with-p-peer-reviewed-article-DDDTTest; https://doaj.org/toc/1177-8881Test

الوصول الحر: https://doaj.org/article/80275aef575e4393803db9490babb493Test

المؤلفون: I-Lun Hsin, Huang-Pin Shen, Hui-Yi Chang, Jiunn-Liang Ko, Po-Hui Wang

المصدر: Cells; Volume 10; Issue 11; Pages: 2916

مصطلحات موضوعية: c-Myc, endometrial cancer, mutant p53, dual PI3K/mTOR inhibitor, PQR309

وصف الملف: application/pdf

العلاقة: Cell Proliferation and Division; https://dx.doi.org/10.3390/cells10112916Test

الإتاحة: https://doi.org/10.3390/cells10112916Test

المؤلفون: Wioleta Justyna Omeljaniuk, Rafał Krętowski, Wioletta Ratajczak-Wrona, Ewa Jabłońska, Marzanna Cechowska-Pasko

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 21; Pages: 11511

مصطلحات موضوعية: apoptosis, glioblastoma, dual PI3K/mTOR inhibitor, GDC-0980, apitolisib

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms222111511Test

الإتاحة: https://doi.org/10.3390/ijms222111511Test

المؤلفون: Jilly F. Evans, Ryan W. Rue, Alexander R. Mukhitov, Kseniya Obraztsova, Carly J. Smith, Vera P. Krymskaya

المصدر: Biomolecules; Volume 10; Issue 1; Pages: 28

مصطلحات موضوعية: lymphangioleiomyomatosis (LAM), TSC2-null, rapamycin, S6K/S6, 4E-BP1/eIF4E, MNK1/2 inhibitor, PI3k/mTOR inhibitor

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Medicine; https://dx.doi.org/10.3390/biom10010028Test

الإتاحة: https://doi.org/10.3390/biom10010028Test

المؤلفون: Cretella, Daniele, Ravelli, Andrea, Fumarola, Claudia, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Alfieri, Roberta, Biondi, Alessandra, Generali, Daniele, Bonelli, Mara, Petronini, Pier Giorgio

المساهمون: Cretella, Daniele, Ravelli, Andrea, Fumarola, Claudia, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Alfieri, Roberta, Biondi, Alessandra, Generali, Daniele, Bonelli, Mara, Petronini, Pier Giorgio

مصطلحات موضوعية: CDK4/6 inhibition, Glucose metabolism, Palbociclib, PI3K/mTOR inhibitor, Triple-negative breast cancer, Oncology, Cancer Research

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29587820; info:eu-repo/semantics/altIdentifier/wos/WOS:000428516300006; volume:37; issue:1; firstpage:"-"; lastpage:"-"; numberofpages:12; journal:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH; http://hdl.handle.net/11368/2935420Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85044545269; https://jeccr.biomedcentral.com/articles/10.1186/s13046-018-0741-3Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872523Test/

الإتاحة: https://doi.org/10.1186/s13046-018-0741-3Test
http://hdl.handle.net/11368/2935420Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872523Test/