المؤلفون: Cristiano Rumio, Fabrizio Marcucci

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 234-245 (2021)

مصطلحات موضوعية: 0301 basic medicine, PFKFB3, PFKFB isoform 3, Cancer Research, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, OXPHOS, oxidative phosphorylation, ATG, autophagy related, Apoptosis, Drug resistance, Review Article, TKI, tyrosine kinase inhibitor, Oxidative Phosphorylation, 0302 clinical medicine, Neoplasms, Glycolysis, NADPH, nicotinamide adenine dinucleotide phosphate reduced, media_common, LDH, lactate dehydrogenase, Chemistry, ABC, ATP-binding cassette, mTOR, mechanistic target of rapamycin, EMT, TME, tumor microenvironment, PFKFB, phosphofructo-2-kinase/fructose-2,6-biphosphatase, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell biology, GLUT, glucose transporter, Mitochondria, HIF, hypoxia-inducible factor, PGK1, PGK isoform 1, ENO, enolase, 030220 oncology & carcinogenesis, Efflux, EMT, epithelial-mesenchymal transition, PI3K, phosphoinositide 3-kinase, Drug, PDK1, PDK isoform 1, ATP, adenosine triphosphate, Epithelial-Mesenchymal Transition, media_common.quotation_subject, DDR, DNA damage repair, HK2, HK isoform 2, PPP, pentose phosphate pathway, Antineoplastic Agents, lcsh:RC254-282, 03 medical and health sciences, ROS, reactive oxygen species, Cell Line, Tumor, PGK, phosphoglycerate kinase, PFKP, PFK platelet type, Animals, Humans, LDHA, LDH isoform A, mAb, monoclonal antibody, Tumors, Tumor microenvironment, Innate immune system, Autophagy, Danger, HK, hexokinase, PDH, pyruvate dehydrogenase, EGFR, epidermal growth factor receptor, Metabolic pathway, 030104 developmental biology, Glucose, Drug Resistance, Neoplasm, PK, pyruvate kinase, PKM2, PK isoform M2, ALDO, fructose biphosphate aldolase, ENO1, ENO isoform 1, Energy Metabolism, PDK, pyruvate dehydrogenase kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa5b30ce2ee01dd517b432844e879a6Test
http://europepmc.org/articles/PMC7804361Test

المؤلفون: Dileep N. Lobo, Despina Constantin, Dumitru Constantin-Teodosiu, Paul L. Greenhaff, Kristina K. Varadhan

المصدر: Clinical Nutrition (Edinburgh, Scotland)

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, Critical Care and Intensive Care Medicine, Systemic inflammation, MAFbx, muscle atrophy F-box, TNF-α, tumour necrosis factor α, Postoperative Complications, MuRF1, muscle-RING finger 1, 0302 clinical medicine, IR, insulin resistance, FOXO, forkhead box O, Abdomen, Insulin, Nutrition and Dietetics, Muscle inflammatory responses, Middle Aged, 3. Good health, PDC, pyruvate dehydrogenase complex, Cytokines, LPS, lipopolysaccharide, Female, IRS1, insulin receptor substrate 1, medicine.symptom, Adult, CSTL1, cathepsin, medicine.medical_specialty, Abdominal surgery, Inflammation, Protein degradation, PI3K/Akt1, phosphotidyl inositol 3-kinase/protein kinase B, Article, PPAR, perioxisome proliferator-activated receptor, Proinflammatory cytokine, 03 medical and health sciences, Pancreatectomy, Atrophy, PCA, perchloric acid, Digestive System Physiological Phenomena, Diabetes mellitus, Internal medicine, FFA, free fatty acid, medicine, Humans, Muscle, Skeletal, Herniorrhaphy, business.industry, RA, rectus abdominus, Metabolic response, medicine.disease, IL, interleukin, 030104 developmental biology, Endocrinology, Postoperative hyperglycaemia, VL, vastus lateralis, Hyperglycemia, Blood sugar regulation, Gene expression, business, PDK, pyruvate dehydrogenase kinase, 030217 neurology & neurosurgery

وصف الملف: PDF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45af6490ed64e6453fc8635e60761a6Test
https://doi.org/10.1016/j.clnu.2017.10.020Test

المؤلفون: Baolin Liu, Ning Zhang, Aiyun Li, Qiang Li, Yang Yang, Qun Liu

المصدر: EBioMedicine

مصطلحات موضوعية: Male, 0301 basic medicine, Berberine, HGP, Hepatic glucose production, TAC, Tricarboxylic acid cycle, Mitochondria, Liver, PGC-1α, Peroxisome proliferator-activated receptor-γ coactivator-1α, Mitochondrial Membrane Transport Proteins, KCT, β-ketoacyl CoA thiolase, THP, 3-(2,2,2-Trimethylhydrazine) propionate (also known as mildronate), chemistry.chemical_compound, AMP-activated protein kinase, Pyruvic Acid, PDK, Pyruvate dehydrogenase kinase, TC, Total cholesterol, Beta oxidation, Cells, Cultured, Mice, Inbred ICR, biology, Chemistry, Acetyl-CoA, DCA, Dichloroacetate, General Medicine, Pyruvate dehydrogenase complex, Pyruvate carboxylase, Liver, Biochemistry, NAM, Nicotinamide, Research Paper, Monocarboxylic Acid Transporters, G-6-Pase, Glucose-6-phosphatase, HFD, High-fat diet, Pyruvate dehydrogenase kinase, Anion Transport Proteins, MPC, Mitochondrial pyruvate carrier, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, TG, Triglyceride, 03 medical and health sciences, Oxygen Consumption, SIRT3, Sirtuin3, Animals, Humans, Sirtuin3, PEPCK, Phosphoenolpyruvate carboxykinase, LDH, Lactate dehydrogenase, Gluconeogenesis, Lipid Metabolism, FACD, Fatty acyl CoA dehydrogenase, PC, Pyruvic carboxylase, Citric acid cycle, AMPK, AMP-activated protein kinase, Mitochondrial pyruvate carrier 1, Glucose, 030104 developmental biology, NEFAs, Non-esterified free fatty acids, biology.protein, PDH, Pyruvate dehydrogenase, TMZ, Trimetazidine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f87be8bc1a2643328b6ffba7fe7d517Test
https://doi.org/10.1016/j.ebiom.2018.07.039Test

المؤلفون: Balaraman Kalyanaraman

المصدر: Redox Biology, Vol 12, Iss, Pp 833-842 (2017)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, H2O, water, Teaching Materials, CoA, acetyl-coenzyme A, OXPHOS, oxidative phosphorylation, Clinical Biochemistry, Review Article, KRAS, V-Ki-ras2 Kirsten rat sarcoma, CO2, carbon dioxide, Biochemistry, G-6P, glucose-6-phosphate, Adenosine Triphosphate, MAGL, monoacylglycerol lipase, MDR, multidrug resistance, NAD+, nicotinamide adenine dinucleotide, Neoplasms, Glycolysis, FDG, fluorinated deoxyglucose, lcsh:QH301-705.5, lcsh:R5-920, LDH, lactate dehydrogenase, FAD, flavin adenine dinucleotide, Warburg effect, Mitochondria, VDAC, voltage-dependent anion channel, LN, lonidamine, BrP, bromopyruvate, GAPDH, glyceraldehyde-3-phosphate, GLUT, glucose transporters, lcsh:Medicine (General), Metabolic Networks and Pathways, ATP, adenosine triphosphate, GIAN, Global Initiative of Academic Networks, ETC, electron transport chain, TCA, tricarboxylic acid, Context (language use), Computational biology, Biology, PET, positron emission tomography, 03 medical and health sciences, 2-DG, 2-deoxyglucose, FFA, free fatty acid, medicine, Animals, Humans, MCT, monocarboxylate transporter, IDH-2, isocitrate dehydrogenase-2, Glutaminolysis, Organic Chemistry, Cancer, TPP+, triphenylphosphonium, HK, hexokinase, NADPH, nicotinamide adenine dinucleotide phosphate, medicine.disease, HIF-1, hypoxia-inducible factor 1, PDH, pyruvate dehydrogenase, Metabolic pathway, 030104 developmental biology, lcsh:Biology (General), Anaerobic glycolysis, PK, pyruvate kinase, Cancer cell, Energy Metabolism, FAO, fatty acid oxidation, PHGDH, 3-phosphoglycerate dehydrogenase, PDK, pyruvate dehydrogenase kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c07eef5656544c37ea719b7c0334068Test
https://doi.org/10.1016/j.redox.2017.04.018Test

المؤلفون: Natalie M. Niemi, David J. Pagliarini

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, A-kinase-anchoring protein, Pyruvate dehydrogenase kinase, Proteome, ASBMB Award Article, AKAP, A-kinase anchoring protein, PKL, protein kinase-like, BCKDK, Biology, Mitochondrion, Biochemistry, Mitochondrial Proteins, 03 medical and health sciences, Phosphoprotein Phosphatases, Animals, Humans, Protein phosphorylation, Phosphorylation, Protein kinase A, Molecular Biology, 030102 biochemistry & molecular biology, protein phosphatase, Phosphoproteomics, phosphoproteomics, protein kinase, Cell Biology, BCKDK, branched chain amino acid dehydrogenase kinase, Phosphoproteins, PDH, pyruvate dehydrogenase, protein phosphorylation, Cell biology, mitochondria, 030104 developmental biology, MS, mass spectrometry, PTM, posttranslational modification, MTS, mitochondrial targeting sequence, Protein Kinases, PDK, pyruvate dehydrogenase kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68b73f81bd517bffe410584103fb6ceTest
https://doi.org/10.1016/j.jbc.2021.100880Test

المؤلفون: Khanti Rattanapornsompong, Pannapa Pinweha, Sarawut Jitrapakdee, Varodom Charoensawan

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 223-233 (2016)

مصطلحات موضوعية: 0301 basic medicine, TFs, transcription factors, PSAT, phosphoserine aminotransferase, Metabolic network, ACC, acetyl-CoA carboxylase, BRCA1, breast cancer type 1 susceptibility protein, Biochemistry, G6PD, glucose-6-phosphate dehydrogenase, PFK, phosphofructokinase, Serine, PC, pyruvate carboxylase, 0302 clinical medicine, GLS, glutaminase, Structural Biology, FH, fumarate hydratase, PSPH, phosphoserine phosphatase, Cancer, Genetics, p53, tumor protein p53, MicroRNA, SHMT, serine hydroxymethyl transferase, FAS, fatty acid synthase, ME, malic enzyme, Computer Science Applications, Cell biology, GLUT, glucose transporter, ACL, ATP-citrate lyase, PGK, phosphoglycerate kinase (PGK), MCT, monocarboxylic acid transporter, 030220 oncology & carcinogenesis, SDH, succinate dehydrogenase, Biotechnology, lcsh:Biotechnology, PHGDH, phosphoglycerate dehydrogenase, Biophysics, TCA, tricarboxylic acid, GDH, glutamate dehydrogenase, IDH, isocitrate dehydrogenase, PPP, pentose phosphate pathway, Biology, 03 medical and health sciences, lcsh:TP248.13-248.65, HIF1α, hypoxia inducible factor 1α, microRNA, Transcription factor, Gene, SREBP1, sterol regulatory element binding protein 1, Oncogene, Transcriptional regulation network, PEP, phosphoenolpyruvate, HK, hexokinase, PKM, muscle-pyruvate kinase, PDH, pyruvate dehydrogenase, Sterol regulatory element-binding protein, 030104 developmental biology, 2-HG, 2-hydroxyglutarate, Metabolism, Anaerobic glycolysis, Sterol Regulatory Element Binding Protein 1, PEPCK, phosphoenolpyruvate carboxykinase, Short Survey, c-MYC, V-myc avian myelocytomatosis viral oncogene homolog, miR/miRNA, LDH, lactate dehydrogenase micro RNA, PDK, pyruvate dehydrogenase kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268eb25358d62f10bdd206de1d1c97d9Test
https://pubmed.ncbi.nlm.nih.gov/27358718Test

المؤلفون: M. Gulrez Zariwala, Mary C. Sugden, Mark J. Holness, Celia G. Walker

المصدر: FEBS Open Bio

مصطلحات موضوعية: medicine.medical_specialty, ISO, isoproterenol, Pyruvate dehydrogenase kinase, TAG, triacylglycerol, ADO, adenosine, PDK4, Peroxisome proliferator-activated receptor, Adipose tissue, Hormone-sensitive lipase, PPAR, peroxisome proliferator-activated receptor, Biology, General Biochemistry, Genetics and Molecular Biology, Article, MLP, maternal low protein, PC, pyruvate carboxylase, chemistry.chemical_compound, Downregulation and upregulation, Pyruvate dehydrogenase complex, SCD, stearoyl-CoA desaturase, Internal medicine, Adipocyte, Gene expression, medicine, KRHB, Krebs–Ringer HEPES buffer, chemistry.chemical_classification, NEFA, non-esterified fatty acid, Lipogenesis, WAT, white adipose tissue, Adenosine, Endocrinology, chemistry, CON, control, PDC, pyruvate dehydrogenase complex, Programming, PEPCK, phosphoenolpyruvate carboxykinase, lipids (amino acids, peptides, and proteins), BSA, bovine serum albumin, HSL, hormone-sensitive lipase, PDK, pyruvate dehydrogenase kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac4b479704ade634aa49f94e38b3aa5Test
https://pubmed.ncbi.nlm.nih.gov/23650578Test