المؤلفون: Zhouhong Ge, Ron Smits, Lucia Campos Carrascosa, Dave Sprengers, Jaap Kwekkeboom, Jan N. M. IJzermans, Guoying Zhou, Maikel P. Peppelenbosch, Ruby Lieshout, Ling Wang, Wanlu Cao, Lisanne Noordam, Pengfei Li, Qin Yang, Junhong Su, Jiaye Liu, Luc J. W. van der Laan, Meng Li, Buyun Ma, Monique M A Verstegen, Qiuwei Pan, Ruyi Zhang

المساهمون: Gastroenterology & Hepatology, Surgery

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 11(2), 407-431. Elsevier Inc.

مصطلحات موضوعية: FAP, fibroblast-associated protein, 0301 basic medicine, IGF, insulin-like growth factor, Liver Tumor Organoids, Wnt, wingless-related integration site, Cell–Cell Contact, Mice, PCR, polymerase chain reaction, Liver Neoplasms, Experimental, 0302 clinical medicine, Cancer-Associated Fibroblasts, Tumor Cells, Cultured, Tumor Microenvironment, Diethylnitrosamine, Paracrine Effect, OEM, organoids expansion medium, Original Research, AFP, α-fetoprotein, Liver Neoplasms, Gastroenterology, ECM, extracellular matrix, Organoids, EpCAM, epithelial cell adhesion molecule, NSG, NOD scid γ mouse, FACS, fluorescence-activated cell sorter, 030211 gastroenterology & hepatology, Liver cancer, medicine.drug, Sorafenib, CCA, cholangiocarcinoma, Carcinoma, Hepatocellular, Stromal cell, Liver tumor, Primary Cell Culture, PBS, phosphate-buffered saline, Antineoplastic Agents, Biology, α-SMA, α-smooth muscle actin, Co-Culture, PDGFRA, platelet-derived growth factor receptor α, 03 medical and health sciences, Paracrine signalling, SDG 3 - Good Health and Well-being, 3D, 3-dimensional, Paracrine Communication, OBM, organoids basic medium, medicine, Animals, Humans, CAF, cancer-associated fibroblast, EGF, epidermal growth factor, Hepatology, Cancer, DEN, N-nitrosodiethylamine, medicine.disease, CSC, cancer stem cell, Xenograft Model Antitumor Assays, Coculture Techniques, FGF, fibroblast growth factor, IL, interleukin, 030104 developmental biology, Drug Resistance, Neoplasm, Culture Media, Conditioned, Cancer cell, Cancer research, TCGA, The Cancer Genome Atlas, DMEM, Dulbecco’s modified Eagle medium, 5-FU, 5-fluorouracil, HGF, hepatocyte growth factor, FCS, fetal calf serum, Stromal Cells, HCC, hepatocellular carcinoma

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf0768c949717d28cf96aa15fc39b91Test
https://doi.org/10.1016/j.jcmgh.2020.09.003Test

المؤلفون: Michele A. Battle, Emily M. Walker, Bridget M. Kohlnhofer, Cayla A. Thompson

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 2, Pp 189-209 (2016)

مصطلحات موضوعية: EdU, 5-ethynyl-2'deoxyuridine, 0301 basic medicine, Prdm1, PR domain containing 1, endocrine system, Frizzled, Morphogenesis, Biology, Pdgfa, platelet-derived growth factor α, Villus Morphogenesis, Bio-ChIP-Seq, biotin-mediated chromatin immunoprecipitation with high-throughput sequencing, cKO, conditional knockout, SBS, short-bowel syndrome, PDGFRA, platelet-derived growth factor receptor α, 03 medical and health sciences, PCR, polymerase chain reaction, Cyclin D2, medicine, Olfm4, olfactomedin 4, lcsh:RC799-869, Sonic hedgehog, reproductive and urinary physiology, Original Research, Transcriptional Regulation, Hes1/6, hairy and enhancer of split-1/6, E, embryonic day, Hepatology, WNT Signaling, Ccnd1/2, cyclin D1/2, Cdk6, cyclin-dependent kinase 6, Atoh, atonal homolog 1, Gastroenterology, Wnt signaling pathway, Fzd5, frizzled 5, respiratory system, Intestinal epithelium, Molecular biology, Epithelium, 030104 developmental biology, medicine.anatomical_structure, Wnt, wingless type MMTV integration site family, embryonic structures, Shh, sonic hedgehog, cardiovascular system, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, Endoderm

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82fd5716bbb6773e37720f300cbfbe6Test

المؤلفون: Sachin Shivaji Rathod, Dattatraya Muzumdar, Sandhya B. Rani, Mohsina Khan, Anjali Shiras

المصدر: FEBS Open Bio, Vol 4, Iss C, Pp 485-495 (2014)
FEBS Open Bio

مصطلحات موضوعية: Beta-catenin, Mesenchymal, qRT-PCR, quantitative real time PCR, GSC, glioma stem cell, PARP, poly ADP-ribose polymerases, CNS, central nervous system, mTORC2, Article, General Biochemistry, Genetics and Molecular Biology, Rictor, bFGF, basic fibroblast growth factor, Glioma, medicine, Epithelial–mesenchymal transition, neoplasms, Protein kinase B, lcsh:QH301-705.5, GSK-3β, glycogen synthase kinase 3β, TCGA, the cancer genome atlas database, PI3K/AKT/mTOR pathway, EGF, epidermal growth factor, EV, empty vector, NOD/SCID, nonobese diabetic/severe combined immunodeficiency, biology, PDGFRA, platelet-derived growth factor receptor-α, Wnt signaling pathway, GBM, glioblastoma multiforme, medicine.disease, nervous system diseases, GIC, glioma initiating cell, lcsh:Biology (General), biology.protein, Cancer research, Stem cell, Heterogeneity, Glioblastoma, EMT, epithelial–mesenchymal transition

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57f3444d53734329ba31047c9edb191Test
http://www.sciencedirect.com/science/article/pii/S2211546314000503Test