المؤلفون: Min Luo, Yuhui Xia, Fang Wang, Hong Zhang, Danting Su, Chaoyue Su, Chuan Yang, Shaocong Wu, Sainan An, Suxia Lin, Liwu Fu

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3120-3133 (2021)

مصطلحات موضوعية: ERK1/2, PD-L1, PD-1, PD0325901, NSCLC, Immunotherapy, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211383521000824Test; https://doaj.org/toc/2211-3835Test

الوصول الحر: https://doaj.org/article/83595ed1c09242bdb64a0a0ee9fac465Test

المؤلفون: Yang Yu, Xiaoxiao Wang, Xiaoxin Zhang, Yanhua Zhai, Xukun Lu, Haixia Ma, Kai Zhu, Tongbiao Zhao, Jianwei Jiao, Zhen-Ao Zhao, Lei Li

المصدر: Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Extracellular signal-regulated protein kinase, Neural differentiation, PD0325901, Epiblast stem cells, Embryonic stem cells, Medicine (General), R5-920, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s13287-017-0750-8Test; https://doaj.org/toc/1757-6512Test

الوصول الحر: https://doaj.org/article/764aa9c206ec4311b97d8dcf2be4e4deTest

المؤلفون: Christelle Bahlawane, Martine Schmitz, Elisabeth Letellier, Karthik Arumugam, Nathalie Nicot, Petr V. Nazarov, Serge Haan

المصدر: Data in Brief, Vol 9, Iss C, Pp 828-838 (2016)

مصطلحات موضوعية: c-KIT, PDGFRα, MAPK, PI3K, Gastro-intestinal stromal tumours, PD0325901, Stem cell factor, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2352340916306539Test; https://doaj.org/toc/2352-3409Test

الوصول الحر: https://doaj.org/article/8777d9f01a19411a8f19c48cf24c678bTest

المؤلفون: Canizo, Jesica R., Ynsaurralde Rivolta, Amada Eugenia, Vazquez Echegaray, Camila, Suvá, Mariana, Alberio, Virgilia, Aller Atucha, Juan Florencio, Guberman, Alejandra S., Salamone, Daniel Felipe, Alberio, Ricardo H., Alberio, Ramiro

المصدر: Developmental Biology ; Vol.19 ; 1-13 ; https://bmcdevbiol.biomedcentral.comTest/

مصطلحات موضوعية: HYPOBLAST, EPIBLAST, SOX17, NANOG, BOVINE EMBRYOS, LINEAGE SEGREGATION, PD0325901, LIF, T2IGÖ, WNT INHIBITOR

وصف الملف: application/pdf

العلاقة: http://ri.agro.uba.ar/greenstone3/library/collection/arti/document/2019canizoTest

الإتاحة: https://doi.org/10.1186/s12861-019-0193-9Test
http://ri.agro.uba.ar/greenstone3/library/collection/arti/document/2019canizoTest

المؤلفون: Yun Wu, Zili Chen, Zhenjun Yang, Ping Xu, Hongyan He, Xinjie Liu, Chao Wang, Xiaoxiao Li, Jianjun Hou, Lihe Zhang

المصدر: Molecules, Vol 18, Iss 11, Pp 13957-13978 (2013)

مصطلحات موضوعية: RGD-MEKI conjugate, MEK1/2 kinase inhibitor, PD0325901, RGD peptide, integrin αvβ3 receptor, tumor-targeted drug delivery, Organic chemistry, QD241-441

وصف الملف: electronic resource

العلاقة: http://www.mdpi.com/1420-3049/18/11/13957Test; https://doaj.org/toc/1420-3049Test

الوصول الحر: https://doaj.org/article/1895603840ca4f86a26953272fe4efbeTest

المؤلفون: Bahlawane, Christelle, Schmitz, Martine, Letellier, Elisabeth, Arumugam, Karthik, Nicot, Nathalie, Nazarov, Petr, Haan, Serge

المصدر: Data in Brief (9), 828-838 (2016-11)

مصطلحات موضوعية: Gastro-intestinal stromal tumours, MAPK, PD0325901, Stem cell factor, c-KIT, PI3K, Human health sciences, Oncology, Sciences de la santé humaine, Oncologie

العلاقة: http://www.ncbi.nlm.nih.gov/pubmed/27872880Test; urn:issn:2352-3409; https://orbilu.uni.lu/handle/10993/32170Test; info:hdl:10993/32170; https://orbilu.uni.lu/bitstream/10993/32170/1/Bahlawane%20et%20al.%2c%20data%20in%20brief.pdfTest; scopus-id:2-s2.0-85020932629; info:pmid:27872880; wos:000453170500136

الإتاحة: https://doi.org/10.1016/j.dib.2016.10.026Test
https://orbilu.uni.lu/handle/10993/32170Test
https://orbilu.uni.lu/bitstream/10993/32170/1/Bahlawane%20et%20al.%2c%20data%20in%20brief.pdfTest

المؤلفون: Anaïs F. Bardet, Daniel Hess, Daniel Olivieri, Sébastien A. Smallwood, Ulrich Elling, Sujani Paramanathan, Joerg Betschinger

المساهمون: Friedrich Miescher Institute for Biomedical Research (FMI), Novartis Research Foundation, Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences (OeAW)

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (2), pp.100947. ⟨10.1016/j.jbc.2021.100947⟩
The Journal of Biological Chemistry

مصطلحات موضوعية: 2C, 2-cell embryo, TF, transcription factor, Aucun, BTB-link, extended BTB domain, Biochemistry, Ep400, chromatin remodeling, 0302 clinical medicine, i, inhibitor, Phylogeny, transcription factor, 2i, two inhibitors, Zinc finger, 0303 health sciences, LIF, leukemia inhibitory factor, bFGF, basic FGF, Zinc Fingers, KD, knock-down, Chromatin, Cell biology, N2B27, chemically defined base medium, Histone, BTB-POZ Domain, mESC, mouse embryonic stem cell, HiRA, histone regulator A, ChIP-seq, chromatin immunoprecipitation sequencing, EpiLC, epiblast-like cell, NuRD, nucleosome remodeling and deacetylase, Research Article, FDR, false discovery rate, Two-hybrid screening, DOX, doxycycline, Biology, Chromatin remodeling, 03 medical and health sciences, 2iLIF, N2B27 containing LIF, CHIR, and PD0325901, NuRD, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], MEK, mitogen-activated protein kinase kinase, Humans, CHIR, CHIR99021, Nucleosome, Histone Chaperones, Epigenetics, AP-MS, affinity purification–MS, Molecular Biology, Transcription factor, 030304 developmental biology, epigenetics, LFQ, label-free quantification, GSK3, glycogen synthetase kinase 3, PBST, PBS–0.1% Tween-20, Cell Biology, Y2H, yeast-2-hybrid, embryonic stem cell, HiRA, FGF, fibroblast growth factor, Repressor Proteins, ZBTB2, serum-LIF, fetal calf serum–containing medium supplemented with LIF, histone chaperone, BTB, broad-complex, tramtrack, and bric-a-brac, biology.protein, qPCR, quantitative PCR, Znf, zinc-finger domain, 030217 neurology & neurosurgery, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026739c7c937a26878c6cad73fcd7ad9Test

المؤلفون: Fang Wang, Shaocong Wu, Sainan An, Liwu Fu, Hong Zhang, Chaoyue Su, Yuhui Xia, Suxia Lin, Chuan Yang, Min Luo, Danting Su

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3120-3133 (2021)

مصطلحات موضوعية: MAPK/ERK pathway, PD-L1, Combination therapy, medicine.medical_treatment, Cell, RM1-950, NSCLC, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Cancer immunotherapy, PD-1, Carcinoma, medicine, General Pharmacology, Toxicology and Pharmaceutics, 030304 developmental biology, 0303 health sciences, biology, ERK1/2, business.industry, PD0325901, Immunotherapy, medicine.disease, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Original Article, Therapeutics. Pharmacology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511abb96c69bd6c702a55c6e46c2a269Test
https://pubmed.ncbi.nlm.nih.gov/34729305Test

المؤلفون: Marco Meloni, Paolo Madeddu, Rajesh Katare, Andrea Caporali, Massimo Caputo, Anita C Thomas, Daryl O. Schwenke, Elisa Avolio

المصدر: Avolio, E, Katare, R G, Thomas, A C, Caporali, A, Schwenke, D, Meloni, M, Caputo, M & Madeddu, P R 2020, ' Contractile reprogramming of cardiac pericytes by MEK inhibition promotes arteriologenesis of the ischemic heart ', bioRxiv . https://doi.org/10.1101/2020.11.10.376772Test

مصطلحات موضوعية: Matrigel, Arteriologenesis, Capillarization, Cardiac pericyte, ERK1/2, PD0325901, Vascular smooth muscle cell, Myocardial infarction, Vascular smooth muscle, business.industry, Basic fibroblast growth factor, Smooth muscle contraction, Pharmacology, medicine.disease, Mural cell, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Arteriole, medicine.artery, Medicine, Myocardial infarction, Pericyte, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb799abce1b352f5b2436de55ad6bc28Test
https://doi.org/10.1101/2020.11.10.376772Test

المؤلفون: Avolio, Elisa, Katare, Rajesh G, Thomas, Anita C, Caporali, Andrea, Schwenke, Daryl, Meloni, Marco, Caputo, Massimo, Madeddu, Paolo R

المصدر: Avolio , E , Katare , R G , Thomas , A C , Caporali , A , Schwenke , D , Meloni , M , Caputo , M & Madeddu , P R 2020 , ' Contractile reprogramming of cardiac pericytes by MEK inhibition promotes arteriologenesis of the ischemic heart ' , bioRxiv . https://doi.org/10.1101/2020.11.10.376772Test

مصطلحات موضوعية: Arteriologenesis, Capillarization, Cardiac pericyte, ERK1/2, PD0325901, Vascular smooth muscle cell, Myocardial infarction

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1101/2020.11.10.376772Test
https://hdl.handle.net/1983/4e53e9f6-2c1e-4498-92c5-8223ac1f2063Test
https://research-information.bris.ac.uk/en/publications/4e53e9f6-2c1e-4498-92c5-8223ac1f2063Test
https://research-information.bris.ac.uk/ws/files/260509714/2020.11.10.376772v1.full.pdfTest