المؤلفون: Manuel Schweighauser, Alexey G. Murzin, Jennifer Macdonald, Isabelle Lavenir, R. Anthony Crowther, Sjors H.W. Scheres, Michel Goedert

المصدر: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-11 (2023)

مصطلحات موضوعية: P301S tau, Frontotemporal dementia and parkinsonism linked to chromosome 17, Transgenic mice, Electron cryo-microscopy, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2051-5960Test

الوصول الحر: https://doaj.org/article/43edd87f5ecc46a6b3d9100ebbe7d73fTest

المؤلفون: Sravan Gopalkrishnashetty Sreenivasmurthy, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Rambabu N. Reddi, Ananth Kumar Kammala, Karthick Vasudevan, Sanjib Senapati, Zhou Zhu, Cheng-Fu Su, Jia Liu, Xin-Jie Guan, Ka-Kit Chua, King-Ho Cheung, Hubiao Chen, Hong-Jie Zhang, Yuan Zhang, Ju-Xian Song, Siva Sundara Kumar Durairajan, Min Li

المصدر: Frontiers in Molecular Biosciences, Vol 9 (2022)

مصطلحات موضوعية: Alzheimer’s disease, PRO-Br, chaperone-mediated autophagy, HDAC6, 3xTg-AD, P301S tau, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fmolb.2022.1030534/fullTest; https://doaj.org/toc/2296-889XTest

الوصول الحر: https://doaj.org/article/ad4864ffb5f248789897756ed41a5785Test

المؤلفون: Karthikeyan Selvarasu, Abhay Kumar Singh, Ashok Iyaswamy, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Amal Kanti Bera, Jian-Dong Huang, Siva Sundara Kumar Durairajan

المصدر: Frontiers in Molecular Biosciences, Vol 9 (2022)

مصطلحات موضوعية: Alzheheimer’s disease, tau pathology, kinesin I, KIF5B, P301S tau mice, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fmolb.2022.1050768/fullTest; https://doaj.org/toc/2296-889XTest

الوصول الحر: https://doaj.org/article/4e8d22d8f5fe4895961e823ed31add61Test

المؤلفون: A. Iyaswamy, S. K. Krishnamoorthi, Y. W. Liu, J. X. Song, A. K. Kammala, S. G. Sreenivasmurthy, S. Malampati, B. C. K. Tong, K. Selvarasu, K. H. Cheung, J. H. Lu, J. Q. Tan, C. Y. Huang, S. S. K. Durairajan, M. Li

المصدر: Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: Alzheimer’s disease, P301S tau mice, neurofibrillary tangles, Chinese medicine, yuan-hu zhi tong, microarray, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2020.584770/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/a00de7624c6d44b58425bd6fa986cb04Test

المؤلفون: Schweighauser, Manuel, Murzin, Alexey G, Macdonald, Jennifer, Lavenir, Isabelle, Crowther, R Anthony, Scheres, Sjors HW, Goedert, Michel

مصطلحات موضوعية: Electron cryo-microscopy, Frontotemporal dementia and parkinsonism linked to chromosome 17, P301S tau, Transgenic mice, Humans, Mice, Animals, Cryoelectron Microscopy, Transgenic, tau Proteins, Tauopathies, Brain, Cytoskeleton, Disease Models, Animal

وصف الملف: application/zip; text/xml; application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/361136Test

الإتاحة: https://www.repository.cam.ac.uk/handle/1810/361136Test

المؤلفون: Kundel, Franziska, De, Suman, Flagmeier, Patrick, Horrocks, Mathew H, Kjaergaard, Magnus, Shammas, Sarah L, Jackson, Sophie E, Dobson, Christopher M, Klenerman, David

المصدر: Kundel , F , De , S , Flagmeier , P , Horrocks , M H , Kjaergaard , M , Shammas , S L , Jackson , S E , Dobson , C M & Klenerman , D 2018 , ' Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity ' , ACS chemical biology , vol. 13 , no. 3 , pp. 636-646 . https://doi.org/10.1021/acschembio.7b01039Test

مصطلحات موضوعية: ALPHA-SYNUCLEIN, ALZHEIMERS-DISEASE, CHAPERONE, FIBRILS, NEURONAL PC12 CELLS, OLIGOMERS, P301S TAU, PAIRED HELICAL FILAMENT, PROTEIN HOMEOSTASIS, SINGLE-MOLECULE FLUORESCENCE

الإتاحة: https://doi.org/10.1021/acschembio.7b01039Test
https://pure.au.dk/portal/da/publications/hsp70-inhibits-the-nucleation-and-elongation-ofTest-tau-and-sequesters-tau-aggregates-with-high-affinity(e8aaade5-fbc9-4be7-b5cc-4414ad578e41).html
http://www.scopus.com/inward/record.url?scp=85044031536&partnerID=8YFLogxKTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374916/pdf/cb7b01039.pdfTest

المؤلفون: Karthikeyan Selvarasu, Abhay Kumar Singh, Ashok Iyaswamy, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Amal Kanti Bera, Jian-Dong Huang, Siva Sundara Kumar Durairajan

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, Alzheheimer’s disease, tau pathology, kinesin I, KIF5B, P301S tau mice

العلاقة: https://figshare.com/articles/figure/Image1_Reduction_of_kinesin_I_heavy_chain_decreases_tau_hyperphosphorylation_aggregation_and_memory_impairment_in_Alzheimer_s_disease_and_tauopathy_models_jpg/21393090Test

الإتاحة: https://doi.org/10.3389/fmolb.2022.1050768.s001Test
https://figshare.com/articles/figure/Image1_Reduction_of_kinesin_I_heavy_chain_decreases_tau_hyperphosphorylation_aggregation_and_memory_impairment_in_Alzheimer_s_disease_and_tauopathy_models_jpg/21393090Test

المؤلفون: Sravan Gopalkrishnashetty Sreenivasmurthy, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Rambabu N. Reddi, Ananth Kumar Kammala, Karthick Vasudevan, Sanjib Senapati, Zhou Zhu, Cheng-Fu Su, Jia Liu, Xin-Jie Guan, Ka-Kit Chua, King-Ho Cheung, Hubiao Chen, Hong-Jie Zhang, Yuan Zhang, Ju-Xian Song, Siva Sundara Kumar Durairajan, Min Li

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, Alzheimer’s disease, PRO-Br, chaperone-mediated autophagy, HDAC6, 3xTg-AD, P301S tau

العلاقة: https://figshare.com/articles/figure/Image2_Bromo-protopine_a_novel_protopine_derivative_alleviates_tau_pathology_by_activating_chaperone-mediated_autophagy_for_Alzheimer_s_disease_therapy_TIF/21398907Test

الإتاحة: https://doi.org/10.3389/fmolb.2022.1030534.s002Test
https://figshare.com/articles/figure/Image2_Bromo-protopine_a_novel_protopine_derivative_alleviates_tau_pathology_by_activating_chaperone-mediated_autophagy_for_Alzheimer_s_disease_therapy_TIF/21398907Test

المؤلفون: Brelstaff, Jack, Ossola, Bernardino, Neher, Jonas J., Klingstedt, Therese, Nilsson, Peter, Goedert, Michel, Grazia Spillantini, Maria, Tolkovsky, Aviva M.

المصدر: Frontiers in Neuroscience. 9(184)

مصطلحات موضوعية: hyperphosphorylated tau, neurofibrillary tangles, transgenic P301S tau mouse, dorsal root ganglion neurons, Alzheimers disease, frontotemporal dementia (FTD), fluorescent vital fibrillar tau dye

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-122224Test
https://liu.diva-portal.org/smash/get/diva2:864273/FULLTEXT01.pdfTest

المؤلفون: Aviva eTolkovsky, Jack eBrelstaff, Bernardino eOssola, Jonas eNeher, Therese eKlingstedt, Peter eNilsson, Michel eGoedert, Maria Grazia eSpillantini

المصدر: Frontiers in Neuroscience, Vol 9 (2015)

مصطلحات موضوعية: Neurofibrillary Tangles, Alzheimer’s disease, Frontotemporal dementia (FTD), Hyperphosphorylated tau, Dorsal root ganglion neurons, transgenic P301S tau mouse, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00184/fullTest; https://doaj.org/toc/1662-453XTest

الوصول الحر: https://doaj.org/article/b8c6bcf6c2fb4cd8a2452a7b888b1838Test