المؤلفون: Tenney, Alan P, Di Gioia, Silvio Alessandro, Webb, Bryn D, Chan, Wai-Man, de Boer, Elke, Garnai, Sarah J, Barry, Brenda J, Ray, Tammy, Kosicki, Michael, Robson, Caroline D, Zhang, Zhongyang, Collins, Thomas E, Gelber, Alon, Pratt, Brandon M, Fujiwara, Yuko, Varshney, Arushi, Lek, Monkol, Warburton, Peter E, Van Ryzin, Carol, Lehky, Tanya J, Zalewski, Christopher, King, Kelly A, Brewer, Carmen C, Thurm, Audrey, Snow, Joseph, Facio, Flavia M, Narisu, Narisu, Bonnycastle, Lori L, Swift, Amy, Chines, Peter S, Bell, Jessica L, Mohan, Suresh, Whitman, Mary C, Staffieri, Sandra E, Elder, James E, Demer, Joseph L, Torres, Alcy, Rachid, Elza, Al-Haddad, Christiane, Boustany, Rose-Mary, Mackey, David A, Brady, Angela F, Fenollar-Cortés, María, Fradin, Melanie, Kleefstra, Tjitske, Padberg, George W, Raskin, Salmo, Sato, Mario Teruo, Orkin, Stuart H, Parker, Stephen CJ, Hadlock, Tessa A, Vissers, Lisenka ELM, van Bokhoven, Hans, Jabs, Ethylin Wang, Collins, Francis S, Pennacchio, Len A, Manoli, Irini, Engle, Elizabeth C

المصدر: Nature Genetics. 55(7)

مصطلحات موضوعية: Biological Sciences, Genetics, Stem Cell Research, Pediatric, Congenital Structural Anomalies, Aetiology, 2.1 Biological and endogenous factors, Animals, Mice, Facial Paralysis, GATA2 Transcription Factor, Motor Neurons, Neurogenesis, Neurons, Efferent, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0w01w8fmTest

المؤلفون: Beyaz, Semir, Chung, Charlie, Mou, Haiwei, Bauer-Rowe, Khristian E, Xifaras, Michael E, Ergin, Ilgin, Dohnalova, Lenka, Biton, Moshe, Shekhar, Karthik, Eskiocak, Onur, Papciak, Katherine, Ozler, Kadir, Almeqdadi, Mohammad, Yueh, Brian, Fein, Miriam, Annamalai, Damodaran, Valle-Encinas, Eider, Erdemir, Aysegul, Dogum, Karoline, Shah, Vyom, Alici-Garipcan, Aybuke, Meyer, Hannah V, Özata, Deniz M, Elinav, Eran, Kucukural, Alper, Kumar, Pawan, McAleer, Jeremy P, Fox, James G, Thaiss, Christoph A, Regev, Aviv, Roper, Jatin, Orkin, Stuart H, Yilmaz, Ömer H

المصدر: Cell Stem Cell. 28(11)

مصطلحات موضوعية: Genetics, Digestive Diseases, Cancer, Stem Cell Research, Human Genome, Stem Cell Research - Nonembryonic - Non-Human, Nutrition, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Underpinning research, Inflammatory and immune system, Carcinogenesis, Diet, High-Fat, Epithelial Cells, Histocompatibility Antigens Class II, Humans, Intestines, MHC-II, antigen presentation, cancer, diet, high-fat diet, intestinal stem cells, microbiome, obesity, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3kj307f4Test

المؤلفون: Somuncular, Ece, Hauenstein, Julia, Khalkar, Prajakta, Johansson, Anne-Sofie, Dumral, Ozge, Frengen, Nicolai S., Gustafsson, Charlotte, Mocci, Giuseppe, Su, Tsu-Yi, Brouwer, Hugo, Trautmann, Christine L., Vanlandewijck, Michael, 1982, Orkin, Stuart H., Mansson, Robert, Luc, Sidinh

المصدر: Stem Cell Reports. 17(7):1546-1560

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-482496Test
https://doi.org/10.1016/j.stemcr.2022.05.014Test
https://uu.diva-portal.org/smash/get/diva2:1689975/FULLTEXT01.pdfTest

المؤلفون: King, Andrew J, Songdej, Duantida, Downes, Damien J, Beagrie, Robert A, Liu, Siyu, Buckley, Megan, Hua, Peng, Suciu, Maria C, Marieke Oudelaar, A, Hanssen, Lars LP, Jeziorska, Danuta, Roberts, Nigel, Carpenter, Stephanie J, Francis, Helena, Telenius, Jelena, Olijnik, Aude-Anais, Sharpe, Jacqueline A, Sloane-Stanley, Jacqueline, Eglinton, Jennifer, Kassouf, Mira T, Orkin, Stuart H, Pennacchio, Len A, Davies, James OJ, Hughes, Jim R, Higgs, Douglas R, Babbs, Christian

المصدر: Nature communications. 12(1)

مصطلحات موضوعية: Chromatin, Erythroid Cells, Animals, Humans, Mice, DNA-Binding Proteins, Transcription Factors, Repressor Proteins, Gene Expression Regulation, Developmental, Gene Silencing, Acetylation, Enhancer Elements, Genetic, Transcriptional Activation, alpha-Globins, zeta-Globins, Histone Deacetylase Inhibitors

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9px708q1Test

المؤلفون: Christodoulou, Constantina, Spencer, Joel A, Yeh, Shu-Chi A, Turcotte, Raphaël, Kokkaliaris, Konstantinos D, Panero, Riccardo, Ramos, Azucena, Guo, Guoji, Seyedhassantehrani, Negar, Esipova, Tatiana V, Vinogradov, Sergei A, Rudzinskas, Sarah, Zhang, Yi, Perkins, Archibald S, Orkin, Stuart H, Calogero, Raffaele A, Schroeder, Timm, Lin, Charles P, Camargo, Fernando D

المصدر: Nature. 578(7794)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Transplantation, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Regenerative Medicine, Stem Cell Research - Nonembryonic - Non-Human, Underpinning research, 1.1 Normal biological development and functioning, Animals, Bone Remodeling, Cell Movement, Cell Proliferation, Cell Survival, Female, Genes, Reporter, Hematopoietic Stem Cells, Hypoxia, MDS1 and EVI1 Complex Locus Protein, Male, Mice, Molecular Imaging, Oxygen, Skull, fms-Like Tyrosine Kinase 3, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1n90468cTest

المؤلفون: Ariës, Ingrid M, Bodaar, Kimberly, Karim, Salmaan A, Chonghaile, Triona Ni, Hinze, Laura, Burns, Melissa A, Pfirrmann, Maren, Degar, James, Landrigan, Jack T, Balbach, Sebastian, Peirs, Sofie, Menten, Björn, Isenhart, Randi, Stevenson, Kristen E, Neuberg, Donna S, Devidas, Meenakshi, Loh, Mignon L, Hunger, Stephen P, Teachey, David T, Rabin, Karen R, Winter, Stuart S, Dunsmore, Kimberly P, Wood, Brent L, Silverman, Lewis B, Sallan, Stephen E, Van Vlierberghe, Pieter, Orkin, Stuart H, Knoechel, Birgit, Letai, Anthony G, Gutierrez, Alejandro

المصدر: Journal of Experimental Medicine. 215(12)

مصطلحات موضوعية: Childhood Leukemia, Hematology, Genetics, Cancer, Stem Cell Research, Pediatric, Rare Diseases, Pediatric Cancer, Development of treatments and therapeutic interventions, 1.1 Normal biological development and functioning, Underpinning research, 5.1 Pharmaceuticals, Antineoplastic Agents, Apoptosis, Cell Line, Tumor, Drug Resistance, Neoplasm, Female, Gene Expression Regulation, Leukemic, Humans, Male, Mitochondria, Neoplasm Proteins, Polycomb Repressive Complex 2, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Transcription, Genetic, Up-Regulation, Medical and Health Sciences, Immunology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2rh339qtTest

المؤلفون: Yien, Yvette Y, Shi, Jiahai, Chen, Caiyong, Cheung, Jesmine TM, Grillo, Anthony S, Shrestha, Rishna, Li, Liangtao, Zhang, Xuedi, Kafina, Martin D, Kingsley, Paul D, King, Matthew J, Ablain, Julien, Li, Hojun, Zon, Leonard I, Palis, James, Burke, Martin D, Bauer, Daniel E, Orkin, Stuart H, Koehler, Carla M, Phillips, John D, Kaplan, Jerry, Ward, Diane M, Lodish, Harvey F, Paw, Barry H

المصدر: Journal of Biological Chemistry. 293(51)

مصطلحات موضوعية: Nutrition, Digestive Diseases, Hematology, 1.1 Normal biological development and functioning, Underpinning research, Blood, Animals, Erythroid Cells, Erythropoiesis, Erythropoietin, Ferrochelatase, HEK293 Cells, Heme, Humans, Iron, Membrane Proteins, Mice, Mitochondria, Mitochondrial Membranes, Mitochondrial Proteins, Protein Transport, heme, iron metabolism, cell metabolism, erythrocyte, erythropoiesis, red blood cell, Chemical Sciences, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology

الوصول الحر: https://escholarship.org/uc/item/0qr1j5bwTest

المؤلفون: Cha, Hye Ji, Uyan, Ozgun, Kai, Yan, Liu, Tianxin, Zhu, Qian, Tothova, Zuzana, Botten, Giovanni A, Xu, Jian, Yuan, Guo-Cheng, Dekker, Job, Orkin, Stuart H

المساهمون: Biochemistry and Molecular Biotechnology, Morningside Graduate School of Biomedical Sciences, Neurology, Systems Biology

المصدر: Nature communications ; 12 ; 1 ; 6241 ; United States ; England

مصطلحات موضوعية: Differentiation, Genomics

العلاقة: Nature Communications; https://doi.org/10.1038/s41467-021-26574-4Test; Cha HJ, Uyan Ö, Kai Y, Liu T, Zhu Q, Tothova Z, Botten GA, Xu J, Yuan GC, Dekker J, Orkin SH. Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture. Nat Commun. 2021 Oct 29;12(1):6241. doi:10.1038/s41467-021-26574-4. PMID: 34716321; PMCID: PMC8556400.; http://hdl.handle.net/20.500.14038/51668Test

الإتاحة: https://doi.org/10.1038/s41467-021-26574-4Test
https://doi.org/20.500.14038/51668Test
https://hdl.handle.net/20.500.14038/51668Test

المؤلفون: Morris, Vivian, Wang, Dahai, Li, Zhiheng, Marion, William, Hughes, Travis, Sousa, Patricia, Harada, Taku, Sui, Shannan Ho, Naumenko, Sergey, Kalfon, Jérémie, Sensharma, Prerana, Falchetti, Marcelo, Vinicius da Silva, Renan, Candelli, Tito, Schneider, Pauline, Margaritis, Thanasis, Holstege, Frank CP, Pikman, Yana, Harris, Marian, Stam, Ronald W, Orkin, Stuart H, Koehler, Angela N, Shalek, Alex K, North, Trista E, Pimkin, Maxim, Daley, George Q, Lummertz da Rocha, Edroaldo, Rowe, R Grant

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering

المصدر: Elsevier

وصف الملف: application/pdf

العلاقة: Cell Reports; https://hdl.handle.net/1721.1/147849Test; Morris, Vivian, Wang, Dahai, Li, Zhiheng, Marion, William, Hughes, Travis et al. 2022. "Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells." Cell Reports, 39 (4).

الإتاحة: https://hdl.handle.net/1721.1/147849Test

المؤلفون: Manieri, Elisa, Tie, Guodong, Malagola, Ermanno, Seruggia, Davide, Madha, Shariq, Maglieri, Adrianna, Huang, Kun, Fujiwara, Yuko, Zhang, Kevin, Orkin, Stuart H., Wang, Timothy C., He, Ruiyang, McCarthy, Neil, Shivdasani, Ramesh A.

المساهمون: Foundation for the National Institutes of Health

المصدر: Nature Communications ; volume 14, issue 1 ; ISSN 2041-1723

مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41467-023-43619-yTest
https://www.nature.com/articles/s41467-023-43619-y.pdfTest
https://www.nature.com/articles/s41467-023-43619-yTest