| الوصف: |
COVID-19 is a multisystem infection that mainly affects the respiratory system, but also causes systemic inflammation, endothelialitis and thrombosis. The consequences of this are multisystem dysfunction of all organs and systems. In this systematic review, we sought to evaluate the clinical course and outcomes in stroke patients as a complication of COVID-19. To do this, a search was carried out in the PubMed and Embase database for keywords - stroke, ONMC, COVID – 19, thrombosis, ischemia and CVZ. The aim was to identify the incidence of stroke and mortality from stroke in patients with COVID – 19. 146 articles were found on this topic, from April 2020 to March 2021. The meta-analysis included only those studies in which patients with a positive PCR result for SARS-CoV-2 and with a confirmed violation of cerebral circulation participated. Out of 146 studies, we selected 8 articles in which 3427 patients participated. Among patients with SARS-CoV-2, 17% were hospitalized with cerebrovascular diseases, 13% with ischemic, and 3% with hemorrhagic strokes. Compared with the uninfected or with the control group, patients with SARS-CoV2 infection had a relatively increased risk of ischemic stroke (HR = 1.72, 95% CI = 1.56-1.89) The risks of intrahospital mortality from cerebrovascular diseases were much higher in SARS-CoV-2 infected compared to the control group (HR = 2.7, 95% CI = 1.02-5.79). SARS-CoV-2 seems to be associated with an increased risk of developing cerebrovascular diseases, in particular, with ischemic stroke. It may also be associated with an increased risk of mortality. |
