المؤلفون: Betelehem Solomon Bera, Taylor V. Thompson, Eric Sosa, Hiroko Nomaru, David Reynolds, Robert A. Dubin, Shahina B. Maqbool, Deyou Zheng, Bernice E. Morrow, John M. Greally, Masako Suzuki

المصدر: Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-13 (2023)

مصطلحات موضوعية: Single-cell, Open-chromatin regions, Multiplexing, Assay for transposase-accessible chromatin (ATAC), Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-8935Test

الوصول الحر: https://doaj.org/article/f1b57dbd9eda4373b99c5082f8dfd9c5Test

المؤلفون: Xionghui Zhou, Haizi Zheng, Hailu Fu, Kelsey L. Dillehay McKillip, Susan M. Pinney, Yaping Liu

المصدر: Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Cell-free DNA, Fragmentation hotspots, Open chromatin regions, Cancer early detection, Tissues-of-origin, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-994XTest

الوصول الحر: https://doaj.org/article/9ca69ea715234f7eacc84e879ec4296cTest

المؤلفون: Akash Chandra Das, Aidin Foroutan, Brian Qian, Nader Hosseini Naghavi, Kayvan Shabani, Parisa Shooshtari

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11456

مصطلحات موضوعية: open chromatin regions, GWAS, chromatin accessibility data, complex phenotypes

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Biology; https://dx.doi.org/10.3390/ijms231911456Test

الإتاحة: https://doi.org/10.3390/ijms231911456Test

المؤلفون: Matthew R. Hass (9461202), Daniel Brissette (10954717), Sreeja Parameswaran (6986009), Mario Pujato (105278), Omer Donmez (10954720), Leah C. Kottyan (10954723), Matthew T. Weirauch (8154609), Raphael Kopan (93437)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, 1KO, Open chromatin regions, Zeb transcription factor binding sites, chromatin accessibility, Runx 1 shapes, Runx 1-dependent genome-scale repre., Zeb 2 phenocopies, mK 4 cells, Runx 2-bound Unexpectedly, chromatin accessibility changes, Re-expressing Zeb 2, CRISPR, targets Runt-related transcription ., Runx sites, Runx 1 activity, Runx 1 knockout cells, mouse metanephric mesenchyme-derive.

العلاقة: https://figshare.com/articles/journal_contribution/S2_Fig_-/14765791Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1009574.s002Test

المؤلفون: Matthew R. Hass (9461202), Daniel Brissette (10954717), Sreeja Parameswaran (6986009), Mario Pujato (105278), Omer Donmez (10954720), Leah C. Kottyan (10954723), Matthew T. Weirauch (8154609), Raphael Kopan (93437)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, 1KO, Open chromatin regions, Zeb transcription factor binding sites, chromatin accessibility, Runx 1 shapes, Runx 1-dependent genome-scale repre., Zeb 2 phenocopies, mK 4 cells, Runx 2-bound Unexpectedly, chromatin accessibility changes, Re-expressing Zeb 2, CRISPR, targets Runt-related transcription ., Runx sites, Runx 1 activity, Runx 1 knockout cells, mouse metanephric mesenchyme-derive.

العلاقة: https://figshare.com/articles/journal_contribution/Western_blot_for_Runx1_Runx2_Runx3_and_actin_in_C2C12_mK4_and_mK4-Runx1KO_cells_showing_that_all_three_Runx_proteins_are_expressed_in_C2C12_Runx1_and_Runx2_in_mK4_cells_and_only_Runx2_in_the_mK4-Runx1KO_cells_/14765788Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1009574.s001Test

المؤلفون: Naoki Osato

المصدر: BMC Genomics, Vol 19, Iss S1, Pp 135-151 (2018)

مصطلحات موضوعية: Transcriptional target genes, Functional enrichment, Gene expression, Transcription factors, Enhancer, Open chromatin regions, Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s12864-017-4339-5Test; https://doaj.org/toc/1471-2164Test

الوصول الحر: https://doaj.org/article/8f1665cbab0045d791dbb81dcfbbe61bTest

المؤلفون: Christian A. Lee (10741080), Diala Abd-Rabbo (3840220), Jüri Reimand (10741083)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Molecular Biology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Computational Biology, driver gene discovery, RM, 66 cell types, CTCF binding sites, mutation frequency, core DNA motifs, localised, open-chromatin regions, tissue-specific open-chromatin regions, ARID 1A mutations, mutagenesi, BRAF, SBS, TSS, cancer genomes Abstract Background ., cancer genome evolution, mutation rate variability, enrichment

العلاقة: https://figshare.com/articles/dataset/Additional_file_2_of_Functional_and_genetic_determinants_of_mutation_rate_variability_in_regulatory_elements_of_cancer_genomes/14532255Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14532255.v1Test

المؤلفون: Matthew R. Hass (9461202), Daniel Brissette (10954717), Sreeja Parameswaran (6986009), Mario Pujato (105278), Omer Donmez (10954720), Leah C. Kottyan (10954723), Matthew T. Weirauch (8154609), Raphael Kopan (93437)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, 1KO, Open chromatin regions, Zeb transcription factor binding sites, chromatin accessibility, Runx 1 shapes, Runx 1-dependent genome-scale repre., Zeb 2 phenocopies, mK 4 cells, Runx 2-bound Unexpectedly, chromatin accessibility changes, Re-expressing Zeb 2, CRISPR, targets Runt-related transcription ., Runx sites, Runx 1 activity, Runx 1 knockout cells, mouse metanephric mesenchyme-derive.

العلاقة: https://figshare.com/articles/dataset/This_excel_file_contains_the_RELI_analyses_of_the_ChIP-seq_and_ATAC-seq_peaks_that_shows_the_significant_overlap_with_other_genomic_datasets_/14765821Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1009574.s011Test

المؤلفون: Matthew R. Hass (9461202), Daniel Brissette (10954717), Sreeja Parameswaran (6986009), Mario Pujato (105278), Omer Donmez (10954720), Leah C. Kottyan (10954723), Matthew T. Weirauch (8154609), Raphael Kopan (93437)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, 1KO, Open chromatin regions, Zeb transcription factor binding sites, chromatin accessibility, Runx 1 shapes, Runx 1-dependent genome-scale repre., Zeb 2 phenocopies, mK 4 cells, Runx 2-bound Unexpectedly, chromatin accessibility changes, Re-expressing Zeb 2, CRISPR, targets Runt-related transcription ., Runx sites, Runx 1 activity, Runx 1 knockout cells, mouse metanephric mesenchyme-derive.

العلاقة: https://figshare.com/articles/dataset/This_table_is_an_excel_file_containing_the_RNA-seq_expression_data_presented_as_the_transcripts_per_million_TPM_the_genes_displaying_over_2_fold_change_in_expression_with_an_FDR_of_less_than_0_05_between_the_Runx1KO_and_control_or_ZebDKO_an/14765812Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1009574.s008Test

المؤلفون: Matthew R. Hass (9461202), Daniel Brissette (10954717), Sreeja Parameswaran (6986009), Mario Pujato (105278), Omer Donmez (10954720), Leah C. Kottyan (10954723), Matthew T. Weirauch (8154609), Raphael Kopan (93437)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Evolutionary Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, 1KO, Open chromatin regions, Zeb transcription factor binding sites, chromatin accessibility, Runx 1 shapes, Runx 1-dependent genome-scale repre., Zeb 2 phenocopies, mK 4 cells, Runx 2-bound Unexpectedly, chromatin accessibility changes, Re-expressing Zeb 2, CRISPR, targets Runt-related transcription ., Runx sites, Runx 1 activity, Runx 1 knockout cells, mouse metanephric mesenchyme-derive.

العلاقة: https://figshare.com/articles/dataset/This_excel_file_contains_the_Gene_Ontology_analysis_of_the_biological_pathways_that_are_enriched_in_the_genes_that_are_either_upregulated_or_downregulated_by_over_2_fold_in_the_Runx1KO_cells_compared_to_the_control_cells_/14765815Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1009574.s009Test