المؤلفون: Johannes C.M. Van der Loo, Jerome M. Teitel, Benjamin J. Samelson-Jones, Adam Cuker, Xavier M. Anguela, Marcus E. Carr, Catherine E. McGuinn, Yifeng Chen, Linda B. Couto, Adam Giermasz, Suvankar Majumdar, Katie Wachtel, Jonathan M. Ducore, Stefan Tiefenbacher, Margaret V. Ragni, J. Fraser Wright, Olga Zelenaia, Katherine A. High, Yun Liu, John E.J. Rasko, Daniel Takefman, Lisa M. Sullivan, Angela Winters, Daniel Hui, Alvin Luk, Spencer K. Sullivan, Valder R. Arruda, Lindsey A. George

المصدر: The New England journal of medicine. 377(23)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Adolescent, Genetic Vectors, Hemorrhage, Gastroenterology, Hemophilia B, Factor IX, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Humans, Vector (molecular biology), Transgenes, Adverse effect, Normal range, Clotting factor, Baseline values, business.industry, Hemophilia B Gene, General Medicine, Genetic Therapy, Dependovirus, Middle Aged, 030104 developmental biology, Commentary, Specific activity, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbb2657407ff2d3c3546fcc638e6677Test
https://pubmed.ncbi.nlm.nih.gov/29274719Test

المؤلفون: Romuald Corbau, Olga Zelenaia, Katherine A. High, Sterghios Moschos, Helen Lavender, J. Fraser Wright, David Suhy, Bernd Hauck, Kyle Hayes, Shih-Chu Kao, Laurence O. Whiteley, Tin Mao, B E Souberbielle, Curt Scribner, Andrew D. Burdick, Hubert Denise, Sara H Renison, Alexander A. Kolykhalov, Shangzhen Zhou, Kevin Brady, Peter W. Roelvink

المصدر: Molecular Therapy. 20(9):1737-1749

مصطلحات موضوعية: Pharmacology, Gene knockdown, Hepatitis C virus, B200, Biology, A300, medicine.disease_cause, C700, Virology, Virus, Small hairpin RNA, Transduction (genetics), RNA interference, In vivo, Drug Discovery, medicine, Genetics, Molecular Medicine, Replicon, Molecular Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cf4df837f30b03fa37cdee33a8aa35Test

المؤلفون: Olga Zelenaia, Katherine A. High, Pete Smith, Guang Qu, Jurg M. Sommer, Xingge Liu, Federico Mingozzi, Samuel L. Murphy, J. Fraser Wright, Bernd Hauck

المصدر: Molecular Therapy. 17:144-152

مصطلحات موضوعية: Transcription, Genetic, viruses, Genetic Vectors, Biology, Polymerase Chain Reaction, Epitope, Cell Line, Mice, Transduction (genetics), chemistry.chemical_compound, Capsid, Plasmid, Transcription (biology), Drug Discovery, Genetics, Animals, Humans, Molecular Biology, Gene, Pharmacology, Original Articles, Dependovirus, Molecular biology, Mice, Inbred C57BL, chemistry, Cell culture, Molecular Medicine, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a12ed400c6d85b4c78db8a6c8047ffcTest
https://doi.org/10.1038/mt.2008.227Test

المؤلفون: Olga Zelenaia, Michael B. Robinson

المصدر: Journal of Neurochemistry. 75:2252-2258

مصطلحات موضوعية: Transcription, Genetic, Amino Acid Transport System X-AG, Biology, Cycloheximide, Biochemistry, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Astrocyte differentiation, Epidermal growth factor, Gene expression, medicine, Glutamate aspartate transporter, Animals, RNA, Messenger, RNA Processing, Post-Transcriptional, Cells, Cultured, Protein Synthesis Inhibitors, Messenger RNA, Glutamate receptor, Molecular biology, Rats, medicine.anatomical_structure, Bucladesine, chemistry, Astrocytes, Dactinomycin, biology.protein, ATP-Binding Cassette Transporters, Proto-Oncogene Proteins c-fos, Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee1b015811e38d164a7bef6724acd17Test
https://doi.org/10.1046/j.1471-4159.2000.0752252.xTest

المؤلفون: Arkady Lyubarsky, Jean Bennett, Xiaosong Zhu, Maureen G. Maguire, Eric A. Pierce, Enrico Maria Surace, Kathleen A. Marshall, Barbara A. Konkle, Sandro Banfi, L. F. Dell'Osso, Jeannette L. Bennicelli, Jonathan B. Jacobs, Edwin M. Stone, J. Fraser Wright, Richard W. Hertle, Kenneth S. Shindler, Edward N. Pugh, Nicholas J. Volpe, Jennifer Wellman McDonnell, Katherine A. High, Junwei Sun, Valder R. Arruda, Francesco Testa, Albert M. Maguire, Jian Xing Ma, Alberto Auricchio, Federico Mingozzi, Bernd Hauck, Olga Zelenaia, T. Michael Redmond, Francesca Simonelli, Settimio Rossi

المساهمون: Maguire, Am, Simonelli, Francesca, Pierce, Ea, Pugh EN, Jr, Mingozzi, F, Bennicelli, J, Banfi, Sandro, Marshall, Ka, Testa, Francesco, Surace, Em, Rossi, Settimio, Lyubarsky, A, Arruda, Vr, Konkle, B, Stone, E, Sun, J, Jacobs, J, Dell'Osso, L, Hertle, R, Ma, Jx, Redmond, Tm, Zhu, X, Hauck, B, Zelenaia, O, Shindler, K, Maguire, Mg, Wright, Jf, Volpe, Nj, Mcdonnell, Jw, Auricchio, A, High, Ka, Bennett, J., Simonelli, F, Banfi, S, Testa, F, Surace, Enrico Maria, Rossi, S, Auricchio, Alberto

المصدر: New England Journal of Medicine. 358:2240-2248

مصطلحات موضوعية: Retinal degeneration, medicine.medical_specialty, Visual acuity, Gene therapy of the human retina, genetic structures, business.industry, Genetic enhancement, Genetic transfer, General Medicine, medicine.disease, Article, eye diseases, Choroideremia, Surgery, RPE65, Ophthalmology, medicine, Leber's congenital amaurosis, sense organs, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bedee9d5016d2cd789444b7de1fd948Test
https://doi.org/10.1056/nejmoa0802315Test

المؤلفون: Katherine A. High, Tonia S. Rex, Caroline J. Zeiss, J F Wright, Albert M. Maguire, Daniel Hui, L. F. Dell'Osso, Federico Mingozzi, Valder R. Arruda, Zhangyong Wei, Olga Zelenaia, Shangzhen Zhou, Jean Bennett, Gregory M. Acland, Bernd Hauck, Jeannette L. Bennicelli, Jonathan B. Jacobs, András M. Komáromy, Guang Qu, Daniel C. Chung

المصدر: Molecular Therapy. 16(3):458-465

مصطلحات موضوعية: cis-trans-Isomerases, Visual acuity, genetic structures, Transgene, Kozak consensus sequence, viruses, Genetic Vectors, Optic Atrophy, Hereditary, Leber, Biology, Blindness, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Dogs, Drug Discovery, medicine, Electroretinography, Genetics, Animals, Eye Proteins, Molecular Biology, 030304 developmental biology, Mice, Knockout, Pharmacology, 0303 health sciences, Retina, Retinal pigment epithelium, Dependovirus, Molecular biology, Immunohistochemistry, eye diseases, medicine.anatomical_structure, RPE65, Cis-trans-Isomerases, 030221 ophthalmology & optometry, Molecular Medicine, sense organs, medicine.symptom, Carrier Proteins, Erg

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f49eb472d28be99bd0eeefa6cf4d60dTest

المؤلفون: John H. Wolfe, Olga Zelenaia, Shuy Vang Toan, Deborah Watson, Jeffrey D. Rothstein, Michael B. Robinson, Li Bin Li

المصدر: Journal of Neurochemistry. 97:759-771

مصطلحات موضوعية: Growth factor, medicine.medical_treatment, Glutamate receptor, Biology, Biochemistry, Cell biology, Cellular and Molecular Neuroscience, medicine.anatomical_structure, Epidermal growth factor, medicine, Neuroglia, Signal transduction, Protein kinase B, Transcription factor, Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::825e91b9c8788df2b5750d079f0a708eTest
https://doi.org/10.1111/j.1471-4159.2006.03743.xTest

المؤلفون: John H. Wolfe, Michael B. Robinson, Bala T. S. Susarla, Rebecca P. Seal, Deborah Watson, Susan G. Amara, Olga Zelenaia

المصدر: Journal of Neurochemistry. 91:1151-1163

مصطلحات موضوعية: Neurotransmitter transporter, medicine.medical_specialty, biology, Excitatory Amino Acid Transporter 3, Glutamate receptor, Glutamic acid, Biochemistry, Molecular biology, Cellular and Molecular Neuroscience, medicine.anatomical_structure, Endocrinology, Internal medicine, Symporter, medicine, Glutamate aspartate transporter, biology.protein, Protein kinase C, Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b156cc6beab45f892a036b4877c121d7Test
https://doi.org/10.1111/j.1471-4159.2004.02791.xTest

المؤلفون: Joanna R. Vondrasek, Muhammad Munir, Avtandil Kalandadze, Jeffrey D. Rothstein, Brian D. Schlag, Michael B. Robinson, Olga Zelenaia

المصدر: Molecular Pharmacology. 53:355-369

مصطلحات موضوعية: Amino Acid Transport System X-AG, Cell, Glutamic Acid, Cyclic AMP, Extracellular, medicine, Animals, RNA, Messenger, Protein kinase A, Cells, Cultured, Neurons, Pharmacology, Glial fibrillary acidic protein, biology, Sodium, Glutamate receptor, Immunohistochemistry, Molecular biology, Rats, Molecular Weight, medicine.anatomical_structure, Biotinylation, biology.protein, Molecular Medicine, ATP-Binding Cassette Transporters, Heterologous expression, Neuroglia, Astrocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974855d438be72a9766bd8229dfdb496Test
https://doi.org/10.1124/mol.53.3.355Test

المؤلفون: J Fraser, Wright, Olga, Zelenaia

المصدر: Methods in molecular biology (Clifton, N.J.). 737

مصطلحات موضوعية: Clinical Trials as Topic, Genetic Vectors, Cell Culture Techniques, DNA, Recombinant, Titrimetry, Virion, Guidelines as Topic, Genetic Therapy, Genome, Viral, Dependovirus, Reference Standards, Polymerase Chain Reaction, Cell Line, Workflow, Transduction, Genetic, Humans, Electrophoresis, Polyacrylamide Gel, Safety

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::c09ff7b9f9137f8902672b990b726718Test
https://pubmed.ncbi.nlm.nih.gov/21590401Test