Antiplasmodial Flavonoids fromErythrina sacleuxii
| العنوان: | Antiplasmodial Flavonoids fromErythrina sacleuxii |
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| المؤلفون: | Ogoche J. I. Jondiko, Peter M. Gitu, Julia Wangui, Jacob O. Midiwo, Pamela Liyala, Andrew W. Andayi, Matthias Heydenreich, Abiy Yenesew, Solomon Derese, Norman C. Waters, Hosea Akala, Martin G. Peter |
| المصدر: | Planta Medica. 72:187-189 |
| بيانات النشر: | Georg Thieme Verlag KG, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | Stereochemistry, Plasmodium falciparum, Flavonoid, Drug Resistance, Pharmaceutical Science, Pharmacognosy, complex mixtures, Analytical Chemistry, Antimalarials, chemistry.chemical_compound, Drug Discovery, Animals, Phenols, Erythrina, Flavonoids, Pharmacology, chemistry.chemical_classification, biology, Traditional medicine, Plant Extracts, Organic Chemistry, Chloroquine, biology.organism_classification, Isoflavones, Chromatographic separation, Complementary and alternative medicine, chemistry, Polyphenol, visual_art, Plant Bark, visual_art.visual_art_medium, Institut für Chemie, Molecular Medicine, Erythrina sacleuxii, Bark |
| الوصف: | The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4 -methoxy-3'- prenylisoflavone (trivial name 5-deoxy-3' - prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sucleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence |
| تدمد: | 1439-0221 0032-0943 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1509ed6c95d50ba94cdc9d2aee0234Test https://doi.org/10.1055/s-2005-873200Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....5f1509ed6c95d50ba94cdc9d2aee0234 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14390221 00320943 |
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