المؤلفون: Liang, Yuanke, Voshart, Danielle, Paridaen, Judith T. M. L., Oosterhof, Nynke, Liang, Dong, Thiruvalluvan, Arun, Zuhorn, Inge S., den Dunnen, Wilfred F. A., Zhang, Guojun, Lin, Haoyu, Barazzuol, Lara, Kruyt, Frank A. E.

المصدر: Liang , Y , Voshart , D , Paridaen , J T M L , Oosterhof , N , Liang , D , Thiruvalluvan , A , Zuhorn , I S , den Dunnen , W F A , Zhang , G , Lin , H , Barazzuol , L & Kruyt , F A E 2022 , ' CD146 increases stemness and aggressiveness in glioblastoma and activates YAP signaling ' , Cellular and molecular life sciences , vol. 79 , no. 8 , 398 . https://doi.org/10.1007/s00018-022-04420-0Test

مصطلحات موضوعية: MCAM, Glioblastoma stem cells, Cancer stem cells, EMT, Zebrafish, YAP, EPITHELIAL-MESENCHYMAL TRANSITION, CELL ADHESION MOLECULE, ORGAN SIZE CONTROL, HIPPO PATHWAY, MEMBRANE-PROTEIN, MARKER, TUMORIGENESIS, INHIBITION, EXPRESSION, RESISTANCE

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/89fb25ea-fe83-48c2-8de8-dc8b68a05225Test

الإتاحة: https://doi.org/10.1007/s00018-022-04420-0Test
https://hdl.handle.net/11370/89fb25ea-fe83-48c2-8de8-dc8b68a05225Test
https://research.rug.nl/en/publications/89fb25ea-fe83-48c2-8de8-dc8b68a05225Test
https://pure.rug.nl/ws/files/228238220/Liang2022_Article_CD146IncreasesStemnessAndAggre.pdfTest

المؤلفون: Khuchtumur Bum-Erdene (2145199), I-Ju Yeh (8089505), Giovanni Gonzalez-Gutierrez (53588), Mona K. Ghozayel (9757225), Karen Pollok (6286283), Samy O. Meroueh (1333737)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, paralog transcriptional coactivator, organ size control, order rate constants, cotranscriptional activators like, 4 yielded second, 4 transcriptional activity, taz target genes, several compounds inhibited, molecule cyanamide pan, digit micromolar ic, breast cancer cells, octahydroisoindole small molecules, tead · yap, 50 , taz ), submicromolar ic, mammalian cells, cyanamide electrophile

العلاقة: https://figshare.com/articles/journal_contribution/Small-Molecule_Cyanamide_Pan-TEAD_YAP1_Covalent_Antagonists/21777122Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.2c01189.s001Test

المؤلفون: Zhaocai Zhou, Zengqiang Yuan, Wanjin Hong, Wenqi Wang

المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

مصطلحات موضوعية: Hippo pathway, organ size control, YAP, TAZ, cancer, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fcell.2021.729155/fullTest; https://doaj.org/toc/2296-634XTest

الوصول الحر: https://doaj.org/article/914751f8358c43efaaad697f597ac6a7Test

المؤلفون: Zhou, Zhaocai, Yuan, Zengqiang, Hong, Wanjin, Wang, Wenqi

المصدر: Frontiers in cell and developmental biology, 9

مصطلحات موضوعية: cancer, YAP, Cell and Developmental Biology, TAZ, organ size control, Hippo pathway

العلاقة: https://repository.publisso.de/resource/frl:6474470Test; https://doi.org/10.3389/fcell.2021.729155Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343012Test/

الإتاحة: https://doi.org/10.3389/fcell.2021.729155Test
https://repository.publisso.de/resource/frl:6474470Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343012Test/

المؤلفون: Parker, Joseph, Struhl, Gary

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 117(50), 31935-31944, (2020-12-15)

مصطلحات موضوعية: Dpp Wg morphogens, organ size control, Drosophila wing growth, ecdysone gating, Hippo/Warts tumor suppressor pathway

العلاقة: https://doi.org/10.1073/pnas.2018196117Test; oai:authors.library.caltech.edu:g69qv-bbh84; eprintid:106850; resolverid:CaltechAUTHORS:20201201-070314122

الإتاحة: https://doi.org/10.1073/pnas.2018196117Test

المؤلفون: Hauri, Simon, Wepf, Alexander, van Drogen, Audrey, Varjosalo, Markku, Tapon, Nic, Aebersold, Ruedi, Gstaiger, Matthias

المساهمون: Institute of Biotechnology, Molecular Systems Biology

مصطلحات موضوعية: AP-MS, cell polarity, Hippo signaling, modularity, protein complex analysis, ORGAN SIZE CONTROL, REGULATE CELL-PROLIFERATION, TUMOR-SUPPRESSOR NETWORK, MASS-SPECTROMETRY, DOMAIN PROTEIN, CONTACT INHIBITION, TEAD/TEF FAMILY, GROWTH-CONTROL, FERM-DOMAIN, PATHWAY, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: We would like to thank Y. Zhou, I. Farrance, M. Wehr, J. Kremerskothen and A. Barnekow for providing expression and reporter constructs. This work was supported by the European Union 7th Framework project, PROSPECTS (Proteomics Specification in Space and Time, grant HEALTH-F4-2008-201648) and ERCETH Zurich internal funds to RA, the European Union 7th Framework project, SYBILLA (Systems Biology of T-cell activation) to SH and MG and European Union 7th Framework Marie Curie Actions IEF grant 'Cancer Kinome' (grant no. 236839) to MV.; Hauri , S , Wepf , A , van Drogen , A , Varjosalo , M , Tapon , N , Aebersold , R & Gstaiger , M 2013 , ' Interaction proteome of human Hippo signaling : modular control of the co-activator YAP1 ' , Molecular Systems Biology , vol. 9 , 713 . https://doi.org/10.1002/msb.201304750Test; ORCID: /0000-0002-1340-9732/work/37568877; 84902015859; 3f3aaf3b-cc44-4bf3-a9b4-75c04868a6d6; http://hdl.handle.net/10138/232633Test; 000342502000001

الإتاحة: http://hdl.handle.net/10138/232633Test

المؤلفون: Wang, Y, Xu, X, Maglic, D, Dill, MT, Mojumdar, K, Ng, PK-S, Jeong, KJ, Tsang, YH, Moreno, D, Bhavana, VH, Peng, X, Ge, Z, Chen, H, Li, J, Chen, Z, Zhang, H, Han, L, Du, D, Creighton, CJ, Mills, GB, Camargo, F, Liang, H

المساهمون: SAIC-F-Frederick, Inc, Leidos Biomedical Research, Inc.

المصدر: 1317.e5 ; 1304

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, ORGAN SIZE CONTROL, PANCREATIC-CANCER, TUMOR PROGRESSION, BREAST-CANCER, YAP, PROMOTES, TAZ, GENE, GROWTH, CELLS, TCGA, driver mutation, miRNA regulation, pan-cancer analysis, pathway activity, prognostic power, tumor subtype, Cancer Genome Atlas Research Network

العلاقة: Cell Reports; http://hdl.handle.net/10044/1/71212Test; https://doi.org/10.1016/j.celrep.2018.10.001Test; TCGA Pilot Program; 15Y011ST

الإتاحة: https://doi.org/10.1016/j.celrep.2018.10.001Test
http://hdl.handle.net/10044/1/71212Test

المؤلفون: Yuanke Liang, Daniëlle Voshart, Judith T. M. L. Paridaen, Nynke Oosterhof, Dong Liang, Arun Thiruvalluvan, Inge S. Zuhorn, Wilfred F. A. den Dunnen, Guojun Zhang, Haoyu Lin, Lara Barazzuol, Frank A. E. Kruyt

المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL), Molecular Neuroscience and Ageing Research (MOLAR), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Center for Liver, Digestive and Metabolic Diseases (CLDM), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS)

المصدر: Cellular and molecular life sciences, 79(8):398. SPRINGER BASEL AG

مصطلحات موضوعية: EXPRESSION, INHIBITION, CD146 Antigen, Cellular and Molecular Neuroscience, TUMORIGENESIS, Animals, Molecular Biology, Zebrafish, Pharmacology, HIPPO PATHWAY, Brain Neoplasms, Cancer stem cells, MEMBRANE-PROTEIN, EMT, Cell Biology, Glioma, EPITHELIAL-MESENCHYMAL TRANSITION, CELL ADHESION MOLECULE, ORGAN SIZE CONTROL, MARKER, Molecular Medicine, YAP, Glioblastoma, MCAM, RESISTANCE, Glioblastoma stem cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1511793e511b6bf67dae4af297904edfTest
https://research.rug.nl/en/publications/89fb25ea-fe83-48c2-8de8-dc8b68a05225Test

المؤلفون: Abagnale, Giulio, Sechi, Antonio, Steger, Michael, Zhou, Qihui, Kuo, Chao-Chung, Aydin, Gülcan, Schalla, Carmen, Müller-Newen, Gerhard, Zenke, Martin, Costa, Ivan G, van Rijn, Patrick, Gillner, Arnold, Wagner, Wolfgang

المصدر: Abagnale , G , Sechi , A , Steger , M , Zhou , Q , Kuo , C-C , Aydin , G , Schalla , C , Müller-Newen , G , Zenke , M , Costa , I G , van Rijn , P , Gillner , A & Wagner , W 2017 , ' Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies ' , Stem Cell Reports , vol. 9 , no. 2 , pp. 654-666 . https://doi.org/10.1016/j.stemcr.2017.06.016Test

مصطلحات موضوعية: HIPPO SIGNALING PATHWAY, MULTI-BEAM-INTERFERENCE, ORGAN SIZE CONTROL, SELF-RENEWAL, CONTACT GUIDANCE, TISSUE-CELLS, DIFFERENTIATION, YAP, ADHESION, LINEAGE

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/87132cc9-2371-4197-a7f8-91aa8cb6e4fcTest

الإتاحة: https://doi.org/10.1016/j.stemcr.2017.06.016Test
https://hdl.handle.net/11370/87132cc9-2371-4197-a7f8-91aa8cb6e4fcTest
https://research.rug.nl/en/publications/87132cc9-2371-4197-a7f8-91aa8cb6e4fcTest
https://pure.rug.nl/ws/files/46896322/Surface_Topography_Guides_Morphology_and_Spatial_Patterning_of_Induced_Pluripotent_Stem_Cell_Colonies.pdfTest

المؤلفون: Parsons, Linda M., Grzeschik, Nicola A, Amaratunga, Kasun, Burke, Peter, Quinn, Leonie M, Richardson, Helena E

المصدر: Parsons , L M , Grzeschik , N A , Amaratunga , K , Burke , P , Quinn , L M & Richardson , H E 2017 , ' A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues ' , G3 : Genes, Genomes, Genetics , vol. 7 , no. 8 , pp. 2497-2509 . https://doi.org/10.1534/g3.117.043513Test

مصطلحات موضوعية: cell polarity, Drosophila, phosphoprotein, kinase, phosphatase, Hippo, Wingless, Wnt, Ras, phosphoinositol, PI3K, nutrient sensing, WARTS-HIPPO PATHWAY, LETHAL GIANT LARVAE, ORGAN SIZE CONTROL, TUMOR-SUPPRESSOR, YORKIE ACTIVITY, IMAGINAL DISCS, GROWTH, CRUMBS, PHOSPHORYLATION

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/844c89cc-7e5f-453e-a79c-a36fc26c5fbdTest

الإتاحة: https://doi.org/10.1534/g3.117.043513Test
https://hdl.handle.net/11370/844c89cc-7e5f-453e-a79c-a36fc26c5fbdTest
https://research.rug.nl/en/publications/844c89cc-7e5f-453e-a79c-a36fc26c5fbdTest
https://pure.rug.nl/ws/files/46868479/Evaluation_of_the_impact_of_tumor_HPV_status_on_outcome_in_patients_with_locally_advanced_unresectable_head_and_neck_squamous_cell_carcinoma_HNSCC_receiving_cisplatin_5_fluorouracil_with_or_without_docetaxel.pdfTest