المؤلفون: Mervyn G Thomas, Frank A Proudlock, Irene Gottlob, Catey Bunce, Helena Lee, Sohaib R Rufai, Ravi Purohit

المصدر: Ophthalmology

مصطلحات موضوعية: Male, Fovea Centralis, Longitudinal study, Visual acuity, Achromatopsia, genetic structures, Visual Acuity, ONL, outer nuclear layer, Color Vision Defects, Nystagmus, 0302 clinical medicine, Foveal, Eye Abnormalities, Longitudinal Studies, Prospective Studies, Prospective cohort study, Grading (education), 0303 health sciences, logMAR, logarithm of the minimum angle of resolution, Genetic Diseases, X-Linked, Hypoplasia, Albinism, Oculocutaneous, Child, Preschool, Female, medicine.symptom, Nystagmus, Congenital, Tomography, Optical Coherence, medicine.medical_specialty, Vision Disorders, Article, 03 medical and health sciences, Ophthalmology, medicine, VA, visual acuity, Humans, PL, preferential looking, IQR, interquartile range, 030304 developmental biology, business.industry, Infant, medicine.disease, eye diseases, 030221 ophthalmology & optometry, FDI, foveal developmental index, sense organs, SD, standard deviation, business, OS, outer segment, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1d3d2c93dba5652f105bd3576d2237Test
https://doi.org/10.1016/j.ophtha.2019.10.037Test

المؤلفون: Elena V. Olshevskaya, Alexander M. Dizhoor, Igor V. Peshenko

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Retinal degeneration, genetic structures, CORD6, cone–rod dystrophy 6, ONL, outer nuclear layer, Biochemistry, chemistry.chemical_compound, Mice, GCAP, guanylyl cyclase–activating protein, RD3, retinal degeneration-3 protein, Mice, Knockout, medicine.diagnostic_test, OCT, optical coherence tomography, CNG, cyclic nucleotide–gated channel, Nuclear Proteins, Photoreceptor outer segment, eye, Cell biology, Isoenzymes, medicine.anatomical_structure, calcium-binding proteins, GUCY2D, TTBS, Tris-buffered saline containing 0.5% Tween-20, RD3, Retinitis Pigmentosa, Research Article, Photoreceptor Cells, Vertebrate, Receptors, Cell Surface, HEK293, human embryonic kidney cells 293, LCA12, Leber's congenital amaurosis type 12, cyclic GMP, RetGC, medicine, RetGC, the retinal membrane guanylyl cyclase, Animals, Humans, ROS, rod outer segment, guanylate cyclase (guanylyl cyclase), Outer nuclear layer, Molecular Biology, Retina, ERG, electroretinography, GCAP, Dystrophy, Retinal, Cell Biology, medicine.disease, photoreceptor, Guanylate Cyclase-Activating Proteins, HEK293 Cells, chemistry, Guanylate Cyclase, Mutation, retinal degeneration, sense organs, Electroretinography

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777ae28d6c427ff826d869780f9a510fTest
http://europepmc.org/articles/PMC8517212Test

المؤلفون: Wolfgang Baehr, Cecilia D. Gerstner, Ali Sakawa Sharif, Jeanne M. Frederick, Martha A. Cady, Vadim Y. Arshavsky, Christina Anne Mitchell, Guoxin Ying

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Axoneme, genetic structures, INPP5E, RIS, rod inner segment, ONL, outer nuclear layer, IS, inner segment, Biochemistry, Mice, Retinal Rod Photoreceptor Cells, Morphogenesis, Mice, Knockout, Chemistry, Cilium, rod and cone photoreceptors, Retinal Degeneration, Cell biology, disc morphogenesis, connecting cilium, Protein Transport, medicine.anatomical_structure, Retinal Cone Photoreceptor Cells, CETN2, centrin-2, Visual phototransduction, Research Article, COS, cone outer segment, PI4P, phosphoinositol-4-phosphate, Retina, 03 medical and health sciences, Intraflagellar transport, Joubert syndrome, CC, connecting cilia, medicine, Animals, Outer nuclear layer, Eye Proteins, Molecular Biology, CO, Covance, Inc, INPP5E, phosphatidylinositol polyphosphate 5-phosphatase, ERG, electroretinography, ROS, rod outer segments, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, Phosphoric Monoester Hydrolases, PT, Proteintech, Ciliopathy, PIP2, PI (4, 5)P2, 030104 developmental biology, retina degeneration, sense organs, PFA, paraformaldehyde, IFT, intraflagellar transport, JBTS, Joubert syndrome, OS, outer segment

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a678b53f03ba002421b1df8a573c65a1Test
http://europepmc.org/articles/PMC8047226Test

المؤلفون: Tsutomu Ohashi, Kazuhiko Namekata, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Takayuki Harada

المصدر: Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 29, Iss, Pp 101197-(2022)

مصطلحات موضوعية: GLAST, glutamate/aspartate transporter, GLAST deficient mice, genetic structures, QH301-705.5, GCL, ganglion cell layer, Lighting environment, Biophysics, ONL, outer nuclear layer, Glaucoma, QD415-436, IRL, inner retinal layer, IOP, intraocular pressure, Biochemistry, eye diseases, mfERG, multifocal electroretinogram, RGC, retinal ganglion cell, sense organs, Retinal ganglion cell, Biology (General), Neurodegeneration, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f1ad820997cd39a992a3adb270590aTest
https://doi.org/10.1016/j.bbrep.2021.101197Test

المؤلفون: Binxiang Cai, Chunyan Liao, Danxue He, Jingmeng Chen, Jiahuai Han, Jiaying Lu, Kaiqi Qin, Wenxu Liang, Xiaoling Wu, Zuguo Liu, Yalin Wu

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: p-MLKL, phosphorylated mixed lineage kinase domain-like protein, genetic structures, RIP3, receptor interacting protein kinase 3, ONL, outer nuclear layer, IS, inner segment, Biochemistry, Mice, Stargardt Disease, GSDME, gasdermin E, PCD, programmed cell death, AMD, age-related macular degeneration, qRT–PCR, quantitative real-time PCR, c-Jun N-terminal kinase, reactive oxygen species, LDH, lactate dehydrogenase, Caspase 3, pyroptosis, gasdermin E, apoptosis, RDH8, all-trans-retinol dehydrogenase 8, JNK, c-Jun N-terminal kinase, Retinaldehyde, Stargardt's disease, HMGB1, high-mobility group box 1, Research Article, PARP, poly-ADP-ribose polymerase, Pore Forming Cytotoxic Proteins, RPE, retinal pigment epithelium, GSDME-N, N-terminal fragment of GSDME, IgG, immunoglobulin G, STGD1, Stargardt's disease 1, Retina, atROL, all-trans-retinol, cDNA, complementary DNA, ROS, reactive oxygen species, Animals, Photoreceptor Cells, TEM, transmission electron microscopy, age-related macular degeneration, Molecular Biology, Nec-1, necrostatin-1, NAC, N-acetyl-l-cysteine, Cell Biology, photoreceptor, eye diseases, ABCA4, ABC (subfamily A, member 4) transporter, atRAL, all-trans-retinal, Cyt c, cytochrome c, ATP-Binding Cassette Transporters, sense organs, OS, outer segment

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b29afe488a258683562e75a6793061Test
https://doi.org/10.1016/j.jbc.2021.101553Test

المؤلفون: Hye Jin Kim, Joshua L. Dunaief, Keiko Ueda, Janet R. Sparrow, Diego Montenegro, Jin Zhao, Kevin Zhang

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, retina, retinal pigment epithelium, ONL, outer nuclear layer, RPE, retinal pigment epithelial cells, Biochemistry, Fenton reaction, chemistry.chemical_compound, Mice, iron, Stargardt Disease, AMD, age-related macular degeneration, ONH, optic nerve head, lipofuscin, chemistry.chemical_classification, Mice, Knockout, biology, Cell biology, medicine.anatomical_structure, Retinaldehyde, light, Oxidation-Reduction, Visual phototransduction, Research Article, cis-trans-Isomerases, Genes, Recessive, Lipofuscin, bisretinoid, 03 medical and health sciences, Retinoids, Hepcidin, medicine, Animals, Molecular Biology, Reactive oxygen species, ERG, electroretinography, Retinal pigment epithelium, 030102 biochemistry & molecular biology, Cell Biology, STGD1, Stargardt Disease 1, medicine.disease, eye diseases, Ferritin, 030104 developmental biology, chemistry, ABCA4, ATP-binding cassette, sub-family A, member 4, biology.protein, Hydroxyl radical, ATP-Binding Cassette Transporters, sense organs, qAF, quantitative fundus autofluorescence

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba35195fd6a8c8394dc2511e49becd4cTest
https://pubmed.ncbi.nlm.nih.gov/33402423Test

المؤلفون: Yan Wang, Yalin Wu, Zuguo Liu, Jingmeng Chen, Chao Chen

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, STEAP3, six-transmembrane epithelial antigen of prostate 3, genetic structures, STGD1, autosomal recessive Stargardt disease, TFRC, transferrin receptor, ONL, outer nuclear layer, Mitochondrion, medicine.disease_cause, Biochemistry, Photoreceptor cell, Mice, DMT1, Divalent metal transporter 1, GSH, glutathione, Stargardt Disease, oxidative stress, iron metabolism, AMD, age-related macular degeneration, IREB2, Iron-responsive element binding protein 2, POS, photoreceptor outer segments, chemistry.chemical_classification, Deferoxamine mesylate, LDH, lactate dehydrogenase, Chemistry, TEM, transmission electron microscope, lipid peroxidation, LED, light emitting diode, Cell biology, medicine.anatomical_structure, cell death, Retinaldehyde, Photoreceptor Cells, Vertebrate, Research Article, Programmed cell death, macular degeneration, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Animals, Ferroptosis, Molecular Biology, Reactive oxygen species, Retina, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, all-trans-retinal, photoreceptor, eye diseases, TF, transferrin, Mice, Inbred C57BL, 030104 developmental biology, CP, ceruloplasmin, atRAL, all-trans-retinal, H&E, hematoxylin and eosin, sense organs, FPN, Ferroportin, Reactive Oxygen Species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212aTest
https://pubmed.ncbi.nlm.nih.gov/33334878Test

المؤلفون: Fatimah Matalkah, Jesse Sundar, Visvanathan Ramamurthy, Bohye Jeong, Peter Stoilov

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, TTC8, tetratricopeptide repeat domain 8, Msi1, retina, genetic structures, Cellular differentiation, RNA-binding protein, ONL, outer nuclear layer, PNA, peanut agglutinin, Biochemistry, Synaptic Transmission, Msi2, Musashi, Mice, MAK, male germ cell–associated kinase, RBDs, RNA-binding domains, MSI1, Musashi-1, Mice, Knockout, P, postnatal day, Retinal Degeneration, RNA-Binding Proteins, INL, inner nuclear layer, PBST, PBS supplemented with 0.1% Triton X-100, Photoreceptor outer segment, Cell biology, medicine.anatomical_structure, Photoreceptor Cells, Vertebrate, Research Article, Morphogenesis, Nerve Tissue Proteins, Biology, MSI2, Musashi-2, PDE6β, phosphodiesterase-6β, CC, connecting cilium, 03 medical and health sciences, splicing, Ciliogenesis, medicine, Animals, Cilia, Peripherin 2, Outer nuclear layer, ERG, electroretinographic, Molecular Biology, Vision, Ocular, Retina, 030102 biochemistry & molecular biology, Alternative splicing, Cell Biology, photoreceptor, eye diseases, Alternative Splicing, 030104 developmental biology, sense organs, PRPH2, peripherin-2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f070897ca97db41205f1aa5a154f874Test
https://pubmed.ncbi.nlm.nih.gov/33168629Test

المؤلفون: Yao Chen, Tingting Liu, Wei Wang, Xiaoqin Lu, Eric V. Vukmanic, Sang Joon Lee, Lei Jin, Yongqing Liu, Henry J. Kaplan, Douglas Emery, Douglas C. Dean, Lei Gao

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, 0301 basic medicine, Retinal degeneration, Damp, retina, genetic structures, ONL, outer nuclear layer, RHO, rhodopsin, Biochemistry, SIRPa, signal regulatory protein alpha, chemistry.chemical_compound, Retinal Rod Photoreceptor Cells, Alarmins, Myeloid Cells, myeloid cell, OCT, optimal cutting temperature, biology, Retinal Degeneration, PrCR, programmed cell removal, Cell biology, medicine.anatomical_structure, Rhodopsin, Female, DAMP, danger-associated molecular pattern, Research Article, OS, outer segments, ER, endoplasmic reticulum, 03 medical and health sciences, PBS, phosphate buffered saline, Retinitis pigmentosa, medicine, Animals, Humans, retinal metabolism, RP, retinitis pigmentosa, Outer nuclear layer, Molecular Biology, Retina, 030102 biochemistry & molecular biology, CALR, calreticulin, Endoplasmic reticulum, Retinal, Cell Biology, medicine.disease, photoreceptor, WT, wild-type, 030104 developmental biology, chemistry, biology.protein, BSA, bovine serum albumin, sense organs, IS, inner segments

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d882a7e7fdfae651a7eab550066d7a2dTest
https://doi.org/10.1074/jbc.ra120.016053Test

المؤلفون: Hiroshi Sagara, Hiroshi Kuribayashi, Fumie Hamano, Katsuyuki Nagata, Hideo Shindou, Toshiro Iwagawa, Sumiko Watanabe, Asano Tsuhako, Takao Shimizu

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, RPE, retinal pigment epithelium, Membrane lipids, DHA, docosahexaenoic acid, ONL, outer nuclear layer, LC, long chain, PE, phosphatidylethanolamine, Biochemistry, PC, phosphatidylcholine, VLC, very long chain, 03 medical and health sciences, chemistry.chemical_compound, PUFA, polyunsaturated fatty acid, medicine, SRM, selected reaction monitoring, Outer nuclear layer, Molecular Biology, Phosphatidylethanolamine, DPPC, dipalmitoylphosphatidylcholine, Retina, Retinal pigment epithelium, 030102 biochemistry & molecular biology, Chemistry, Retinal, Cell Biology, Cell sorting, EPA, eicosapentaenoic acid, Cell biology, 030104 developmental biology, medicine.anatomical_structure, sense organs, OS, outer segment, Research Article, Visual phototransduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6c7d130ab644213d3673ad9040d2c4Test
https://doi.org/10.1016/j.jbc.2021.100303Test