المؤلفون: Margolis, Elyssa B, Moulton, Madelyn G, Lambeth, Philip S, O'Meara, Matthew J

مصطلحات موضوعية: Alcoholism, Analgesics, Opioid, Depressive Disorder, Major, Humans, Naltrexone, Narcotic Antagonists, Opioid Peptides, Opioid-Related Disorders, Biomedical and Clinical Sciences, Biological Psychology, Neurosciences, Psychology, Pharmacology and Pharmaceutical Sciences, Substance Misuse, Pain Research, Drug Abuse (NIDA only), Brain Disorders, Aetiology, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Underpinning research, Mental health, Neurological, Good Health and Well Being, Neurology & Neurosurgery, Pharmacology and pharmaceutical sciences, Biological psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4t30p23nTest

المؤلفون: Fassio, Alexandre V, Shub, Laura, Ponzoni, Luca, McKinley, Jessica, O’Meara, Matthew J, Ferreira, Rafaela S, Keiser, Michael J, de Melo Minardi, Raquel C

المصدر: Journal of Chemical Information and Modeling. 62(18)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Good Health and Well Being, Dopamine, Drug Discovery, Ligands, Machine Learning, Proteins, Theoretical and Computational Chemistry, Computation Theory and Mathematics, Medicinal & Biomolecular Chemistry, Medicinal and biomolecular chemistry, Theoretical and computational chemistry

الوصول الحر: https://escholarship.org/uc/item/53z271dnTest

المؤلفون: O’Meara, Matthew J., Rapala, Jackson R., Nichols, Connie B., Alexandre, A. Christina, Billmyre, R. Blake, Steenwyk, Jacob L, Alspaugh, J. Andrew, O’Meara, Teresa R.

المساهمون: Lin, Xiaorong, National Institute of General Medical Sciences, NSURP, National Institute of Allergy and Infectious Diseases, Life Sciences Research Foundation

المصدر: PLOS Genetics ; volume 20, issue 2, page e1011158 ; ISSN 1553-7404

الإتاحة: https://doi.org/10.1371/journal.pgen.1011158Test

المؤلفون: Alon, Assaf, Lyu, Jiankun, Braz, Joao M, Tummino, Tia A, Craik, Veronica, O’Meara, Matthew J, Webb, Chase M, Radchenko, Dmytro S, Moroz, Yurii S, Huang, Xi-Ping, Liu, Yongfeng, Roth, Bryan L, Irwin, John J, Basbaum, Allan I, Shoichet, Brian K, Kruse, Andrew C

المصدر: Nature. 600(7890)

مصطلحات موضوعية: Peripheral Neuropathy, Pain Research, Chronic Pain, Neurosciences, Neurodegenerative, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Ligands, Mice, Neuralgia, Receptors, sigma, Structure-Activity Relationship, General Science & Technology

الوصول الحر: https://escholarship.org/uc/item/9gp7838kTest

المؤلفون: Tummino, Tia A, Rezelj, Veronica V, Fischer, Benoit, Fischer, Audrey, O'Meara, Matthew J, Monel, Blandine, Vallet, Thomas, White, Kris M, Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O'Donnell, Henry R, Lyu, Jiankun, Rosales, Romel, McGovern, Briana L, Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J, Urban, Laszlo, Shokat, Kevan M, Kruse, Andrew C, García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K

المصدر: Science. 373(6554)

مصطلحات موضوعية: Lung, Infectious Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Good Health and Well Being, A549 Cells, Animals, Antiviral Agents, COVID-19, Cations, Chlorocebus aethiops, Dose-Response Relationship, Drug, Drug Repositioning, Female, Humans, Lipidoses, Mice, Microbial Sensitivity Tests, Phospholipids, SARS-CoV-2, Surface-Active Agents, Vero Cells, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/41h684bvTest

المؤلفون: Gordon, David E, Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V, Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S, Obernier, Kirsten, Guo, Jeffrey Z, Batra, Jyoti, Kaake, Robyn M, Weckstein, Andrew R, Owens, Tristan W, Gupta, Meghna, Pourmal, Sergei, Titus, Erron W, Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J, Tummino, Tia A, Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L, Fabius, Jacqueline M, Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M, Naing, Zun Zar Chi, Pulido, Ernst H, Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A, Azumaya, Caleigh M, Billesbølle, Christian, Brilot, Axel F, Campbell, Melody G, Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T, Liu, Yanxin, Merz, Gregory E, Moritz, Michelle, Nguyen, Henry C, Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N, Schulze-Gahmen, Ursula, Smith, Amber M, Sun, Ming, Young, Iris D, Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R, Chen, Jen, Chio, Cynthia M, Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L, Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E, Melo, Arthur A, Moss, Frank R, Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K

المصدر: Science. 370(6521)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Infectious Diseases, Coronaviruses Therapeutics and Interventions, Lung, Coronaviruses, Pneumonia, Emerging Infectious Diseases, Genetics, Biodefense, Pneumonia & Influenza, Generic health relevance, Infection, Good Health and Well Being, COVID-19, Conserved Sequence, Coronavirus Nucleocapsid Proteins, Cryoelectron Microscopy, Host Microbial Interactions, Humans, Mitochondrial Membrane Transport Proteins, Mitochondrial Precursor Protein Import Complex Proteins, Phosphoproteins, Protein Conformation, Protein Interaction Maps, Severe acute respiratory syndrome-related coronavirus, SARS-CoV-2, Severe Acute Respiratory Syndrome, QCRG Structural Biology Consortium, Zoonomia Consortium, General Science & Technology

الوصول الحر: https://escholarship.org/uc/item/46t221r6Test

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O’Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher JP, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C, Cai, Yiming, Chang, Jason CJ, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

المصدر: Nature. 583(7816)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Infectious Diseases, Emerging Infectious Diseases, Coronaviruses, Coronaviruses Therapeutics and Interventions, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Animals, Antiviral Agents, Betacoronavirus, COVID-19, Chlorocebus aethiops, Cloning, Molecular, Coronavirus Infections, Drug Evaluation, Preclinical, Drug Repositioning, HEK293 Cells, Host-Pathogen Interactions, Humans, Immunity, Innate, Mass Spectrometry, Molecular Targeted Therapy, Pandemics, Pneumonia, Viral, Protein Binding, Protein Biosynthesis, Protein Domains, Protein Interaction Mapping, Protein Interaction Maps, Receptors, sigma, SARS-CoV-2, SKP Cullin F-Box Protein Ligases, Vero Cells, Viral Proteins, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2gt3q50xTest
https://escholarship.org/content/qt2gt3q50x/qt2gt3q50x.pdfTest

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, O'Meara, Matthew J, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Shen, Wenqi, Shi, Ying, Zhang, Ziyang, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Mathy, Christopher JP, Perica, Tina, Pilla, Kala B, Ganesan, Sai J, Saltzberg, Daniel J, Ramachandran, Rakesh, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Lin, Yizhu, Wankowicz, Stephanie A, Bohn, Markus, Trenker, Raphael, Young, Janet M, Cavero, Devin, Hiatt, Joe, Roth, Theo, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Roesch, Ferdinand, Vallet, Thomas, Meyer, Björn, White, Kris M, Miorin, Lisa, Agard, David, Emerman, Michael, Ruggero, Davide, García-Sastre, Adolfo, Jura, Natalia, von Zastrow, Mark, Taunton, Jack, Schwartz, Olivier, Vignuzzi, Marco, d'Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S, Fujimori, Danica G, Ideker, Trey, Craik, Charles S, Floor, Stephen, Fraser, James S, Gross, John, Sali, Andrej, Kortemme, Tanja, Beltrao, Pedro, Shokat, Kevan, Shoichet, Brian K, Krogan, Nevan J

مصطلحات موضوعية: Prevention, Vaccine Related, Biodefense, Infectious Diseases, Rare Diseases, Pneumonia & Influenza, Emerging Infectious Diseases, Lung, Pneumonia, 5.1 Pharmaceuticals, 2.2 Factors relating to the physical environment, Infection

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9v71w6zcTest

المؤلفون: Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Pretto, Carla D., Qiao, Yuanyuan, Zhang, Yuping, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Chinnaiyan, Arul M., Sexton, Jonathan Z.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 Sep 01. 118(36), 1-12.

الوصول الحر: https://www.jstor.org/stable/27075439Test

المؤلفون: Lyu, Jiankun, Wang, Sheng, Balius, Trent E, Singh, Isha, Levit, Anat, Moroz, Yurii S, O’Meara, Matthew J, Che, Tao, Algaa, Enkhjargal, Tolmachova, Kateryna, Tolmachev, Andrey A, Shoichet, Brian K, Roth, Bryan L, Irwin, John J

المصدر: Nature. 566(7743)

مصطلحات موضوعية: Theory Of Computation, Medicinal and Biomolecular Chemistry, Chemical Sciences, Built Environment and Design, Information and Computing Sciences, Design, Neurosciences, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Bacterial Proteins, Crystallography, X-Ray, Dopamine Agonists, Humans, Ligands, Machine Learning, Molecular Docking Simulation, Observation, Receptors, Dopamine D4, Small Molecule Libraries, beta-Lactamase Inhibitors, beta-Lactamases, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2k01p3zcTest