نتائج البحث - "Nucleosides/pharmacology"

1

دورية أكاديمية

Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

المصدر: http://lobid.org/resources/99370679188706441Test#!, 40(1):317.

مصطلحات موضوعية: Cell Line, Tumor [MeSH], CNDAC, Humans [MeSH], Acute lymphoblastic leukemia, SAMHD1, Nucleosides/pharmacology [MeSH], Acute myeloid leukemia, Intrinsic resistance, Research, Leukemia, Myeloid, Acute/drug therapy [MeSH], Sapacitabine, DCK, Acquired resistance, Drug Resistance, Neoplasm [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6463851Test; https://doi.org/10.1186/s13046-021-02093-4Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507139Test/

الإتاحة: https://doi.org/10.1186/s13046-021-02093-4Test
https://repository.publisso.de/resource/frl:6463851Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507139Test/

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2

دورية أكاديمية

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

المساهمون: Department of Neuroscience, Yale University School of Medicine, Yale School of Medicine New Haven, Connecticut (YSM), Department of Cell Biology and Physiology, University of North Carolina Chapel Hill (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC), Cellular Neuroscience, Neurodegeneration and Repair Program, Departments of Neurology and Neuroscience New Haven, Section of Comparative Medicine New Haven, Institute of Genetic Medicine, Newcastle University Newcastle, Departments of pharmacology and molecular biophysics and biochemistry New Haven, University of Ljubljana, Département de Virologie - Department of Virology, Institut Pasteur Paris (IP), Departments of Internal Medicine, Cellular & Molecular Physiology, Departments of Medicine and Cell Biology & Physiology, Department of Microbial Pathogenesis, Reproductive Neuroscience Unit, Department of Obstetrics and Gynecology and Department of Neurobiology, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism, Kavli Institute for Neuroscience, Yale School of Medicine, Yale School of Medicine New Haven, Connecticut (YSM)-Yale School of Medicine New Haven, Connecticut (YSM), Departments of Psychiatry and Genetics, This work was supported by grants NS076503, MH103339, MH105972, MH106934, MH060929, NS080388, AG034924, AG047270, DC01919, AI120113, and AI089826 from the NIH, SFARI 307705 from the Simons Foundation, and 15-RMA-YALE-31 from Connecticut Innovations’ Regenerative Medicine Research Fund. The Laboratory of Developmental Biology at the University of Washington, Seattle, and Human Developmental Biology Resource were supported by NIH award number HD0008836 and the Joint MRC/Wellcome Trust grant 099175/Z/12/Z, respectively. Additional support was provided by the Kavli Foundation and the Falk Medical Research Trust.

المصدر: ISSN: 2211-1247.

مصطلحات موضوعية: MESH: Brain/embryology, MESH: Brain/pathology, MESH: Neuroglia/ultrastructure, MESH: Neuroglia/virology, MESH: Microcephaly/pathology, MESH: Neurons/drug effects, MESH: Neurons/pathology, MESH: Neurons/virology, MESH: Cell Death/drug effects, MESH: Neuroprotective Agents/pharmacology, MESH: Nucleosides/pharmacology, MESH: Phosphorylation/drug effects, MESH: Neural Stem Cells/ultrastructure, MESH: Protein Kinase Inhibitors/pharmacology, MESH: Protein-Serine-Threonine Kinases/metabolism, MESH: Proto-Oncogene Proteins/metabolism, MESH: Microcephaly/virology, MESH: Receptor Protein-Tyrosine Kinases/metabolism, MESH: Spinal Cord/pathology, MESH: Transcription, Genetic/drug effects, MESH: Virus Replication/drug effects, MESH: Centrosome/drug effects, MESH: Zika Virus/drug effects, MESH: Neural Stem Cells/virology, MESH: Zika Virus/pathogenicity, MESH: Zika Virus/physiology, MESH: Zika Virus/ultrastructure, MESH: Zika Virus Infection/pathology, MESH: Mitochondria/drug effects

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27568284; pasteur-01739212; https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212Test; https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/documentTest; https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/file/1-s2.0-S2211124716311020-main.pdfTest; PUBMED: 27568284; PUBMEDCENTRAL: PMC5135012

الإتاحة: https://doi.org/10.1016/j.celrep.2016.08.038Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/documentTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-01739212/file/1-s2.0-S2211124716311020-main.pdfTest

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3

دورية أكاديمية

Treatment and prophylaxis of invasive mycoses. - Treatment recommendations / Behandling och profylax av invasiva svampinfektioner. - Behandlingsrekommendation

المؤلفون: Anonymous

المصدر: Information från Läkemedelsverket. 16(6):4

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4

مؤتمر

A world congress on chemotherapy / Världskongress om kemoterapi

المؤلفون: Urban, T

المصدر: Svensk Farmacevtisk Tidskrift. 97(9):28

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5

دورية أكاديمية

Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.

المؤلفون: Rinaldi, Laura, Delle Donne, Rossella, Lindner, Herbert H, Garbi, Corrado, Scorziello, Antonella, Russo, Nicola Antonino, Synofzik, Matthis, Stelzl, Ulrich, Annunziato, Lucio, Stefan, Eduard, Feliciello, Antonio, Catalanotti, Bruno, Torres-Quesada, Omar, Enzler, Florian, Moraca, Federica, Nisticò, Robert, Chiuso, Francesco, Piccinin, Sonia, Bachmann, Verena

المصدر: Nature Communications 10(1), 2572 (2019). doi:10.1038/s41467-019-10037-y

مصطلحات موضوعية: info:eu-repo/classification/ddc/500, Animals, Cyclic AMP: metabolism, Cyclic AMP-Dependent Protein Kinase Catalytic Subunits: metabolism, Feedback, Physiological: drug effects, Physiological: physiology, Fibroblasts, HEK293 Cells, HSP70 Heat-Shock Proteins: antagonists & inhibitors, Hippocampus: pathology, Holoenzymes: metabolism, Humans, Leupeptins: pharmacology, Mice, Inbred C57BL, Molecular Chaperones: metabolism, Phosphorylation, Primary Cell Culture, Protein Binding: drug effects, Proteolysis: drug effects, Purine Nucleosides: pharmacology, Signal Transduction: drug effects, Signal Transduction: physiology, Spinocerebellar Ataxias: genetics, Spinocerebellar Ataxias: pathology, Ubiquitin-Protein Ligases: genetics, Ubiquitin-Protein Ligases: metabolism, Ubiquitination: physiology, HSP70 Heat-Shock Proteins

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/pmid:31189917; info:eu-repo/semantics/altIdentifier/issn/2041-1723; https://pub.dzne.de/record/140751Test; https://pub.dzne.de/search?p=id:%22DZNE-2020-07073%22Test

الإتاحة: https://doi.org/10.1038/s41467-019-10037-yTest
https://pub.dzne.de/record/140751Test
https://pub.dzne.de/search?p=id:%22DZNE-2020-07073%22Test

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6

دورية أكاديمية

Inhibitory effects of acyclic nucleoside phosphonates on human hepatitis B virus and duck hepatitis B virus infections in tissue culture

المؤلفون: Heijtink, R.A. (Rudolf), Kruining, J., Wilde, G.A. de, Balzarini, J., Clercq, E. de, Schalm, S.W. (Solko)

المصدر: Antimicrobial Agents and Chemotherapy

مصطلحات موضوعية: Adenine/analogs & derivatives/pharmacology, Animals, Antiviral Agents/*pharmacology, Carcinoma, Hepatocellular/virology, Cytosine/analogs & derivatives, Ducks, Hepatitis B Virus, Duck/*drug effects, Hepatitis B virus/*drug effects, Humans, Liver Neoplasms/virology, Liver/cytology/virology, Nucleosides/*pharmacology, Organophosphorus Compounds/pharmacology, Phosphonic Acids/*pharmacology, Purines/pharmacology, Tumor Cells, Cultured

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/8564Test; urn:hdl:1765/8564

الإتاحة: http://repub.eur.nl/pub/8564Test

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7

دورية أكاديمية

Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.

المؤلفون: Kuhlmann, F.M., Robinson, J.I., Bluemling, G.R., Ronet, C., Fasel, N., Beverley, S.M.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 5, pp. E811-E819

مصطلحات موضوعية: Animals, Antiviral Agents/pharmacology, Capsid Proteins/genetics, Capsid Proteins/metabolism, Leishmania braziliensis/virology, Leishmania guyanensis/virology, Leishmaniasis/parasitology, Leishmaniavirus/drug effects, Leishmaniavirus/genetics, Leishmaniavirus/metabolism, Mice, Inbred C57BL, Nucleosides/pharmacology, Nucleotides/pharmacology, chemotherapy, endobiont virus, trypanosomatid protozoan parasite, viral segregation, virulence

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28096399; info:eu-repo/semantics/altIdentifier/eissn/1091-6490; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_9466129FAB720; https://serval.unil.ch/notice/serval:BIB_9466129FAB72Test; urn:issn:0027-8424; https://serval.unil.ch/resource/serval:BIB_9466129FAB72.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9466129FAB720Test

الإتاحة: https://doi.org/10.1073/pnas.1619114114Test
https://serval.unil.ch/notice/serval:BIB_9466129FAB72Test
https://serval.unil.ch/resource/serval:BIB_9466129FAB72.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_9466129FAB720Test

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النص الكامل

8

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

المساهمون: Department of Neuroscience [New Haven], Yale University School of Medicine-Kavli Institute for Neuroscience [New Haven], Department of Cell Biology and Physiology, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC), Cellular Neuroscience, Neurodegeneration and Repair Program, Departments of Neurology and Neuroscience [New Haven], Yale University School of Medicine, Section of Comparative Medicine [New Haven], Institute of Genetic Medicine, Newcastle University [Newcastle], Departments of pharmacology and molecular biophysics and biochemistry [New Haven], University of Ljubljana, Département de Virologie - Department of Virology, Institut Pasteur [Paris], Departments of Internal Medicine, Cellular & Molecular Physiology, Departments of Medicine and Cell Biology & Physiology, Department of Microbial Pathogenesis, Reproductive Neuroscience Unit, Department of Obstetrics and Gynecology and Department of Neurobiology, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism, Kavli Institute for Neuroscience [New Haven], Departments of Psychiatry and Genetics, This work was supported by grants NS076503, MH103339, MH105972, MH106934, MH060929, NS080388, AG034924, AG047270, DC01919, AI120113, and AI089826 from the NIH, SFARI 307705 from the Simons Foundation, and 15-RMA-YALE-31 from Connecticut Innovations’ Regenerative Medicine Research Fund. The Laboratory of Developmental Biology at the University of Washington, Seattle, and Human Developmental Biology Resource were supported by NIH award number HD0008836 and the Joint MRC/Wellcome Trust grant 099175/Z/12/Z, respectively. Additional support was provided by the Kavli Foundation and the Falk Medical Research Trust., Department of Neuroscience, Yale University School of Medicine, Yale School of Medicine [New Haven, Connecticut] (YSM), Institut Pasteur [Paris] (IP), Kavli Institute for Neuroscience, Yale School of Medicine, Yale School of Medicine [New Haven, Connecticut] (YSM)-Yale School of Medicine [New Haven, Connecticut] (YSM)

المصدر: Cell Reports
Cell Reports, Elsevier Inc, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, 2016, 16 (10), pp.2576-2592. ⟨10.1016/j.celrep.2016.08.038⟩
Cell Reports, Vol 16, Iss 10, Pp 2576-2592 (2016)

مصطلحات موضوعية: Genetics and Molecular Biology (all), Microcephaly, Transcription, Genetic, Neocortex, MESH: Neuroepithelial Cells/ultrastructure, Biochemistry, environment and public health, MESH: Brain/virology, Neural Stem Cells, MESH: Centrosome/drug effects, MESH: Mitochondria/metabolism, lcsh:QH301-705.5, Neurons, MESH: Protein-Serine-Threonine Kinases/metabolism, Zika Virus Infection, Brain, MESH: Neurons/virology, MESH: Neural Stem Cells/virology, MESH: Neural Stem Cells/immunology, Nucleosides, MESH: Zika Virus/physiology, MESH: Virus Replication/drug effects, Neural stem cell, 3. Good health, Cell biology, Neuroepithelial cell, MESH: Brain/pathology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Spinal Cord, MESH: Neocortex/pathology, MESH: Neuroepithelial Cells/immunology, Neuroglia, MESH: Receptor Protein-Tyrosine Kinases/metabolism, Article, General Biochemistry, Genetics and Molecular Biology, MESH: Protein Kinase Inhibitors/pharmacology, 03 medical and health sciences, MESH: Gene Expression Profiling, Fetus, Humans, MESH: Phosphorylation/drug effects, Mitosis, MESH: Neural Stem Cells/ultrastructure, Biochemistry, Genetics and Molecular Biology (all), MESH: Humans, Receptor Protein-Tyrosine Kinases, MESH: Zika Virus/pathogenicity, medicine.disease, Immunity, Innate, MESH: Mitosis/drug effects, 030104 developmental biology, MESH: Neuroprotective Agents/pharmacology, MESH: Mitochondria/drug effects, MESH: Spinal Cord/pathology, MESH: Neuroglia/ultrastructure, 0301 basic medicine, MESH: Fetus/virology, viruses, [SDV]Life Sciences [q-bio], Neuroepithelial Cells, MESH: Zika Virus/ultrastructure, Virus Replication, MESH: Neurons/drug effects, MESH: Neuroepithelial Cells/drug effects, MESH: Zika Virus Infection/pathology, MESH: Neurons/pathology, MESH: Immunity, Innate/drug effects, Phosphorylation, Genetics, Cell Death, MESH: Transcription, Genetic/drug effects, MESH: Neuroglia/virology, MESH: Nucleosides/pharmacology, Mitochondria, Neuroprotective Agents, MESH: Neuroglia/pathology, lipids (amino acids, peptides, and proteins), MESH: Zika Virus Infection/virology, Stem cell, Programmed cell death, MESH: Centrosome/metabolism, MESH: Brain/embryology, Protein Serine-Threonine Kinases, Biology, Proto-Oncogene Proteins, MESH: Microcephaly/pathology, medicine, MESH: Zika Virus/drug effects, Protein Kinase Inhibitors, Centrosome, MESH: Neural Stem Cells/enzymology, Gene Expression Profiling, MESH: Proto-Oncogene Proteins/metabolism, Zika Virus, Axl Receptor Tyrosine Kinase, MESH: Microcephaly/virology, Gene expression profiling, MESH: Cell Death/drug effects, lcsh:Biology (General), MESH: Neuroepithelial Cells/virology