المؤلفون: Rampadarath, Athika, Balogun, Fatai Oladunni, Pillay, Charlene, Sabiu, Saheed

مصطلحات موضوعية: 1116 Medical Physiology, Humans, Diabetes Mellitus, Type 2, Flavonoids, Glycosides, Enzyme Inhibitors, Hypoglycemic Agents, Protein Tyrosine Phosphatase, Non-Receptor Type 1

وصف الملف: 11 p; Electronic-eCollection

العلاقة: Journal of Diabetes Research; Vol. 2022; Rampadarath, A. et al. 2022. Identification of flavonoid C-glycosides as promising antidiabetics targeting protein tyrosine phosphatase 1B. Journal of Diabetes Research: 6233217-. doi:10.1155/2022/6233217; 2314-6753 (Online); isidoc: 2R1YR; pubmed: 35782627; https://hdl.handle.net/10321/5148Test

الإتاحة: https://doi.org/10.1155/2022/6233217Test
https://hdl.handle.net/10321/5148Test

المؤلفون: Hongdusit, Akarawin, Zwart, Peter H, Sankaran, Banumathi, Fox, Jerome M

المصدر: Nature communications. 11(1)

مصطلحات موضوعية: COS Cells, Animals, Humans, Receptor, Insulin, Recombinant Proteins, Crystallography, X-Ray, Fluorescence Resonance Energy Transfer, Biosensing Techniques, Allosteric Regulation, Phosphorylation, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Phototropins, HEK293 Cells, Optogenetics, Chlorocebus aethiops

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9f41s9gzTest

المؤلفون: Havva Hilal Ayvaz, Kuyaş Hekimler Öztürk, Mehmet Ali Seyirci, Emrah Atay, Selma Korkmaz, İjlal Erturan, Mehmet Yıldırım

المصدر: Dermatology Practical & Conceptual, Vol 13, Iss 2 (2023)

مصطلحات موضوعية: psoriasis, epiregulin, tyrosine-protein phosphatase non-receptor type 1, serine proteinase inhibitors, Dermatology, RL1-803

وصف الملف: electronic resource

العلاقة: https://dpcj.org/index.php/dpc/article/view/2650Test; https://doaj.org/toc/2160-9381Test

الوصول الحر: https://doaj.org/article/b807abe2d71f4b769cb9aee685ef65b2Test

المؤلفون: Keedy, Daniel A, Hill, Zachary B, Biel, Justin T, Kang, Emily, Rettenmaier, T Justin, Brandão-Neto, José, Pearce, Nicholas M, von Delft, Frank, Wells, James A, Fraser, James S

مصطلحات موضوعية: Humans, Crystallography, X-Ray, Temperature, Allosteric Regulation, Binding Sites, Allosteric Site, Protein Conformation, Protein Binding, Kinetics, Mutation, Models, Molecular, Protein Tyrosine Phosphatase, Non-Receptor Type 1, E. coli, allostery, human, molecular biophysics, phosphatase, protein dynamics, structural biology, Crystallography, X-Ray, Models, Molecular, Protein Tyrosine Phosphatase, Non-Receptor Type 1, 1.1 Normal biological development and functioning, Generic Health Relevance, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4tk2c02tTest

المؤلفون: Hjortness, Michael K, Riccardi, Laura, Hongdusit, Akarawin, Ruppe, Sophia, Zhao, Mengxia, Kim, Edward Y, Zwart, Peter H, Sankaran, Banumathi, Arthanari, Haribabu, Sousa, Marcelo C, De Vivo, Marco, Fox, Jerome M

المصدر: Biochemistry. 57(40)

مصطلحات موضوعية: Biochemistry and Cell Biology, Medicinal and Biomolecular Chemistry, Chemical Sciences, Biological Sciences, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Generic health relevance, Abietanes, Humans, Models, Molecular, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Protein Domains, Protein Folding, Protein Kinase Inhibitors, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Medical Biochemistry and Metabolomics, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medical biochemistry and metabolomics, Medicinal and biomolecular chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2kb2q9jjTest

المؤلفون: Ferreira, Vitor, Folgueira, Cintia, García-Altares, María, Guillén, Maria, Ruíz-Rosario, Mónica, DiNunzio, Giada, Garcia-Martinez, Irma, Alen, Rosa, Bookmeyer, Christoph, Jones, John G., Cigudosa, Juan C., López-Larrubia, Pilar, Correig-Blanchar, Xavier, Davis, Roger J., Sabio, Guadalupe, Rada, Patricia, Valverde, Angela M.

مصطلحات موضوعية: Olanzapine, Hypothalamus, Inter-organ crosstalk, Metabolic side-effects, Liver, PTP1B, Male, Animals, Mice, Protein Tyrosine Phosphatase, Non-Receptor Type 1, AMP-Activated Protein Kinases, Knockout, Inflammation, Fatty Acid Synthases, Weight Gain, Inbred C57BL, Signal Transduction, Fatty Liver

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; This work was funded by grants PID-2021-122766OB-100 (to AMV), PID2019-104399RB-I00 (to GS) and RTI2018-096061-B-I00 (to XCB) funded by MCIN/AEI/10.13039/501100011033 and “ERDF A way of making Europe” by the European Union. We also acknowledge grants H2020 Marie Sklodowska-Curie ITN-TREATMENT (Grant Agreement 721236, European Commission), P2022/BMD-7227 (Comunidad de Madrid, Spain), Fundaci´on Ram´on Areces (Spain) and CIBERdem (ISCIII, Spain) to AMV. VF was a recipient of a contract from ITNTREATMENT and is currently a PhD fellow from the Portuguese Foundation for Science and Technology (2020.08388.BD, FCT, Portugal)/ ERDF. CF was awarded with Sara Borrell contract (CD19/00078, ISCIII, Spain). MGA has a postdoctoral contract 2018 BP 00188 funded by AGAUR (Spain), while CB is recipient of a postdoctoral contract from HORIZON-MSCA-2021-PF-01 MASS2 (Proposal number 101067953).; https://hdl.handle.net/10316/112593Test

الإتاحة: https://doi.org/10.1016/j.redox.2023.102741Test
https://hdl.handle.net/10316/112593Test

المؤلفون: Forman, Henry Jay, Davies, Michael J, Krämer, Anna C, Miotto, Giovanni, Zaccarin, Mattia, Zhang, Hongqiao, Ursini, Fulvio

مصطلحات موضوعية: Humans, Hydrogen Peroxide, Disulfides, Oxygen, Amides, Cyclohexanones, Sulfhydryl Compounds, Cysteine, Sulfenic Acids, Glutathione, Signal Transduction, Oxidation-Reduction, Kinetics, Mass Spectrometry, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Hydrogen peroxide, Redox signaling, Sulfenyl amide, Thiolate, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Biochemistry & Molecular Biology, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9wx169fhTest

المؤلفون: Ito, Yoshihiro, Hsu, Ming-Fo, Bettaieb, Ahmed, Koike, Shinichiro, Mello, Aline, Calvo-Rubio, Miguel, Villalba, Jose M, Haj, Fawaz G

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Diabetes, Kidney Disease, Autoimmune Disease, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Renal and urogenital, Animals, Diabetes Mellitus, Experimental, Diabetic Nephropathies, Diet, High-Fat, Hyperglycemia, Kidney, Mice, Mice, Knockout, Podocytes, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Signal Transduction, Diabetic nephropathy, Renal injury, Protein tyrosine phosphatase 1B, Endocrinology & Metabolism, Clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0w53j7t1Test

المؤلفون: Wu, Heng, Zhang, Tianpeng, Pan, Fei, Steer, Clifford J, Li, Zhuoyu, Chen, Xin, Song, Guisheng

المصدر: Journal of Hepatology. 66(4)

مصطلحات موضوعية: Diabetes, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Obesity, Biotechnology, Genetics, Nutrition, Liver Disease, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Metabolic and endocrine, Oral and gastrointestinal, 3' Untranslated Regions, Animals, Diet, High-Fat, Hep G2 Cells, Hepatocytes, Humans, Hyperglycemia, Insulin, Insulin Resistance, Lipogenesis, Liver, Male, Mice, Mice, Inbred C57BL, MicroRNAs, Non-alcoholic Fatty Liver Disease, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Signal Transduction, Sterol Regulatory Element Binding Protein 1, Insulin signaling, NAFLD, Phosphorylation, Diet, high-fat, Clinical Sciences, Public Health and Health Services, Gastroenterology & Hepatology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/16t1m8f4Test

المؤلفون: Zhang, Yixuan, Li, Qiang, Youn, Ji Youn, Cai, Hua

المصدر: Journal of Biological Chemistry. 292(2)

مصطلحات موضوعية: Diabetes, 1.1 Normal biological development and functioning, Underpinning research, Cardiovascular, AMP-Activated Protein Kinases, Animals, Calpain, Cattle, Diabetes Mellitus, Experimental, Endothelial Cells, HEK293 Cells, Humans, Male, Mice, Neovascularization, Physiologic, Nitric Oxide Synthase Type III, Phosphatidylinositol 3-Kinases, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Signal Transduction, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factor Receptor-2, Wound Healing, Akt PKB, PTP1B, VEGFR2, angiogenesis, calpain, diabetes, vascular endothelial growth factor, wound healing, Chemical Sciences, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2zs3n9t6Test