نتائج البحث

1

دورية أكاديمية

Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

المؤلفون: Nina Frey, Luigi Tortola, David Egli, Sharan Janjuha, Tanja Rothgangl, Kim Fabiano Marquart, Franziska Ampenberger, Manfred Kopf, Gerald Schwank

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/ab7c080d5e6c4b88bc1efe5538558f47Test

View record in DOAJ

النص الكامل

2

دورية أكاديمية

Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens

المؤلفون: Kim F. Marquart, Ahmed Allam, Sharan Janjuha, Anna Sintsova, Lukas Villiger, Nina Frey, Michael Krauthammer, Gerald Schwank

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/c9632ae8e3554eb0a6f6c3e3694e3ef8Test

View record in DOAJ

النص الكامل

3

دورية أكاديمية

Pseudomonas aeruginosa airway infection recruits and modulates neutrophilic myeloid-derived suppressor cells

المؤلفون: Hasan Halit Öz, Benyuan Zhou, Pina Voss, Melanie Carevic, Carolin Schroth, Nina Frey, Nikolaus Rieber, Andreas Hector, Dominik Hartl

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)

مصطلحات موضوعية: Cystic Fibrosis, Lung, Pseudomonas aeruginosa, T cells, CFTR, myeloid-derived suppressor cells, Microbiology, QR1-502

وصف الملف: electronic resource

العلاقة: http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00167/fullTest; https://doaj.org/toc/2235-2988Test

الوصول الحر: https://doaj.org/article/17b78e50d0d24f51ab3a6268dad4e019Test

View record in DOAJ

النص الكامل

4

Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens

المؤلفون: Gerald Schwank, Ahmed A. Allam, Nina Frey, Sharan Janjuha, Michael Krauthammer, Kim Marquart, Anna Sintsova, Lukas Villiger

المساهمون: University of Zurich, Krauthammer, Michael, Schwank, Gerald

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature Communications, 12 (1)

مصطلحات موضوعية: CRISPR-Cas9 genome editing, Computer science, Base pair, Science, 10050 Institute of Pharmacology and Toxicology, General Physics and Astronomy, 610 Medicine & health, 1600 General Chemistry, Genomics, Article, General Biochemistry, Genetics and Molecular Biology, Deep Learning, Genome editing, 1300 General Biochemistry, Genetics and Molecular Biology, Basic research, Machine learning, Humans, Data mining, Base Pairing, Throughput (business), Gene Library, Gene Editing, Genome, Multidisciplinary, business.industry, Deep learning, High-Throughput Nucleotide Sequencing, General Chemistry, Base (topology), 3100 General Physics and Astronomy, genomic DNA, 570 Life sciences, biology, Artificial intelligence, business, 11493 Department of Quantitative Biomedicine, Algorithm, Algorithms

وصف الملف: s41467-021-25375-z.pdf - application/pdf; 2020.07.05.186544.full.pdf - application/pdf; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95aa804166a272f8f2463b99035f04b9Test
https://doaj.org/article/c9632ae8e3554eb0a6f6c3e3694e3ef8Test

5

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

المساهمون: Ophthalmology, Graduate School, ACS - Microcirculation, University of Zurich, Semple, Sean C, Schwank, Gerald

المصدر: Nature Biotechnology, 39 (8)
Nature Biotechnology
Nature biotechnology, 39(August 2021). Nature Publishing Group

مصطلحات موضوعية: Male, 10050 Institute of Pharmacology and Toxicology, Applied Microbiology and Biotechnology, PCSK9, Mice, Gene Editing, biology, Genetic engineering, Targeted gene repair, Liver, LDL cholesterol, 1305 Biotechnology, Molecular Medicine, Proprotein Convertase 9, RNA, Guide, Kinetoplastida, Biotechnology, Adult, medicine.medical_specialty, Biomedical Engineering, 2204 Biomedical Engineering, 610 Medicine & health, 10071 Functional Genomics Center Zurich, Bioengineering, Article, Base editing, Abes, Immune system, In vivo, 10049 Institute of Pathology and Molecular Pathology, Internal medicine, 10019 Department of Biochemistry, medicine, Animals, 2402 Applied Microbiology and Biotechnology, Humans, Messenger RNA, 1502 Bioengineering, Adenine, Point mutation, Cholesterol, LDL, biology.organism_classification, Mice, Inbred C57BL, genomic DNA, Endocrinology, 10036 Medical Clinic, 1313 Molecular Medicine, Macaca, CRISPR-Cas Systems, Lipoprotein

وصف الملف: application/application/pdf; Rothgangl_NatBio_41587_2021_Article_933.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ae069a0668f90ce5cdbb49415cc632Test
https://doi.org/10.1038/s41587-021-00933-4Test

6

CRISPR-Based Screening in Three-Dimensional Organoid Cultures to Identify TGF-β Pathway Regulators

المؤلفون: Nina, Frey, Gerald, Schwank

المصدر: Methods in molecular biology (Clifton, N.J.). 2488

مصطلحات موضوعية: Intestines, Organoids, Transforming Growth Factor beta, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Wnt Signaling Pathway

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::31c51bbfc11d1ae95eaee5dee1171086Test
https://pubmed.ncbi.nlm.nih.gov/35347685Test

7

CRISPR-Based Screening in Three-Dimensional Organoid Cultures to Identify TGF-β Pathway Regulators

المؤلفون: Nina Frey, Gerald Schwank

المساهمون: University of Zurich, Zhike, Zi, Xuedong, Liu, Schwank, Gerald

المصدر: Methods in Molecular Biology ISBN: 9781071622766

مصطلحات موضوعية: 1311 Genetics, 1312 Molecular Biology, 570 Life sciences, biology, 10050 Institute of Pharmacology and Toxicology, 610 Medicine & health

وصف الملف: crispr.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d0b4b852808ffc3412d6a625ff00d3Test
https://www.zora.uzh.ch/id/eprint/222952Test/

8

Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing

المؤلفون: Nina Frey, David Egli, Luigi Tortola, Tanja Rothgangl, Franziska Ampenberger, Sharan Janjuha, Gerald Schwank, Kim Fabiano Marquart, Manfred Kopf

مصطلحات موضوعية: Granzyme B, medicine.anatomical_structure, Immune system, Chemistry, T cell, Pancreatic cancer, Cell, Autophagy, medicine, Cancer research, Caspase 8, medicine.disease, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4aa48a6c8d1a5ed15d9b7031fb6b05f7Test
https://doi.org/10.1101/2021.07.29.453937Test

9

Conventional Disease-Modifying Antirheumatic Drugs for the Treatment of Rheumatoid Arthritis

المؤلفون: Shannon Hill, Nina Frey

المصدر: Canadian Journal of Health Technologies. 1

مصطلحات موضوعية: Drug, medicine.medical_specialty, Combination therapy, business.industry, media_common.quotation_subject, General Medicine, Disease, medicine.disease, Internal medicine, Rheumatoid arthritis, medicine, Methotrexate, business, Janus kinase, Antirheumatic drugs, medicine.drug, media_common

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3be8c2b1607cdebe45a43c202f5375a5Test
https://doi.org/10.51731/cjht.2021.72Test

10

Urethral Inserts for the Management of Adult Male Urinary Incontinence

المؤلفون: Srabani Banerjee, Nina Frey

المصدر: Canadian Journal of Health Technologies. 1

مصطلحات موضوعية: medicine.medical_specialty, Adult male, business.industry, Clinical effectiveness, Urology, Medicine, Urinary incontinence, General Medicine, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::50aaf7119ee980483ae1797ad90ffa84Test
https://doi.org/10.51731/cjht.2021.59Test

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