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1دورية أكاديمية
المؤلفون: Maj Petersen, Prafull S. Gandhi, Jens Buchardt, Tomas Alanentalo, Johannes Josef Fels, Nils Langeland Johansen, Peter Helding-Kvist, Knud Vad, Peter Thygesen
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1181 (2020)
مصطلحات موضوعية: somapacitan, human growth hormone, receptor signaling, p-stat5 activation, biodistribution, fluorescence molecular tomography, light-sheet fluorescence microscopy, proximal epiphysis, Biology (General), QH301-705.5, Chemistry, QD1-999
وصف الملف: electronic resource
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المؤلفون: Peter Thygesen, Charlotta G. Folkesson, Charlotte Wiberg, Henrik S. Ramírez-Andersen, Mats Reslow, Jens Buchardt, Per Franklin Nielsen, Xin Zhao, Nils Langeland Johansen, Johannes Josef Fels, Chen Jianhe, Leif Nørskov-Lauritsen, Christian Rischel, Xia Wenjuan, Jing Su, Carsten Behrens
المصدر: Bioconjugate Chemistry. 29:3129-3143
مصطلحات موضوعية: 0301 basic medicine, Alkylation, Biomedical Engineering, Pharmaceutical Science, 030209 endocrinology & metabolism, Bioengineering, Plasma protein binding, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, In vivo, Albumins, Side chain, Animals, Molecule, Pharmacology, Human Growth Hormone, Chemistry, Organic Chemistry, Albumin, Combinatorial chemistry, In vitro, Rats, 030104 developmental biology, Area Under Curve, Oxidation-Reduction, Half-Life, Protein Binding, Biotechnology, Conjugate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82348c015bc30de66842f2cd5ec1fd9Test
https://doi.org/10.1021/acs.bioconjchem.8b00463Test -
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المؤلفون: Tomas Alanentalo, Nils Langeland Johansen, Jens Buchardt, Knud Vad, Peter Thygesen, Prafull S. Gandhi, Johannes Josef Fels, Maj Petersen, Peter Helding-Kvist
المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1181 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 4مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Fluorescence-lifetime imaging microscopy, Growth hormone receptor, Rats, Sprague-Dawley, lcsh:Chemistry, Mice, Pharmaceutical Sciences, 0302 clinical medicine, Tissue Distribution, lcsh:QH301-705.5, Cells, Cultured, Spectroscopy, Chemistry, General Medicine, Human serum albumin, Computer Science Applications, proximal epiphysis, human growth hormone, Female, medicine.drug, medicine.medical_specialty, Biodistribution, receptor signaling, Mice, Nude, 030209 endocrinology & metabolism, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, In vivo, Internal medicine, P-STAT5 activation, medicine, Animals, Humans, Distribution (pharmacology), fluorescence molecular tomography, Physical and Theoretical Chemistry, Molecular Biology, biodistribution, Organic Chemistry, Isothermal titration calorimetry, Receptors, Somatotropin, Farmaceutiska vetenskaper, light-sheet fluorescence microscopy, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, somapacitan, p-stat5 activation, Hepatocytes, Ex vivo
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7858fd82c1582eb0b5f986f6b7db2a5fTest
https://www.mdpi.com/1422-0067/21/4/1181Test -
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المؤلفون: Christian Rischel, Henrik Sune Andersen, Johannes Josef Fels, Leif Nørskov-Lauritsen, Nils Langeland Johansen, Carsten Behrens, Peter Thygesen
المصدر: Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 35
مصطلحات موضوعية: Male, medicine.medical_specialty, Swine, Endocrinology, Diabetes and Metabolism, Drug Evaluation, Preclinical, 030209 endocrinology & metabolism, Absorption (skin), Pharmacology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Pharmacokinetics, In vivo, Internal medicine, Albumins, medicine, Animals, Dosing, Dwarfism, Pituitary, Dose-Response Relationship, Drug, business.industry, Human Growth Hormone, Albumin, Recombinant Proteins, Bioavailability, Rats, Macaca fascicularis, medicine.anatomical_structure, Pharmacodynamics, Swine, Miniature, business, Subcutaneous tissue, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33145513196dfaf7048536431e7ccd55Test
https://pubmed.ncbi.nlm.nih.gov/28595133Test -
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المؤلفون: Joel Martin, Kjeld Madsen, Christian Thomsen, Christian Foged, Jette Platou, Uffe Bang Olsen, Jacob S. Valsborg, Nils Langeland Johansen
المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology. 362:538-545
مصطلحات موضوعية: medicine.medical_specialty, Hypothalamus, Tritium, Binding, Competitive, Partial agonist, Nociceptin Receptor, Substrate Specificity, Rats, Sprague-Dawley, Radioligand Assay, Cricetinae, Internal medicine, medicine, Baby hamster kidney cell, Radioligand, Animals, Humans, Binding site, Receptor, Opioid peptide, Cerebral Cortex, Pharmacology, Binding Sites, Chemistry, Cell Membrane, General Medicine, Amygdala, Rats, Kinetics, Nociceptin receptor, Endocrinology, Opioid Peptides, Receptors, Opioid, Autoradiography, Female, Oligopeptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b90c6534d895911b26665036af0c86Test
https://doi.org/10.1007/s002100000307Test -
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المؤلفون: Kjeld Madsen, Jesper Lau, Thomas Kruse Hansen, Birgit Sehested Hansen, Nils Langeland Johansen, Bernd Peschke, Michael Ankersen
المصدر: European Journal of Medicinal Chemistry. 34:783-790
مصطلحات موضوعية: Pharmacology, Dipeptide, Organic Chemistry, General Medicine, Peptide hormone, Combinatorial chemistry, Chemical synthesis, chemistry.chemical_compound, chemistry, Growth hormone secretagogue, Drug Discovery, Aromatic amino acids, Ipamorelin, GHRP-6, Peptide library
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7333c0d6bfd5e18d2a2ec1932e9ebfb0Test
https://doi.org/10.1016/s0223-5234Test(99)00214-7 -
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المؤلفون: Birgit Sehested Hansen, Henning Thøgersen, Hans Petersen, Jesper Lau, Brett Watson, Thomas Kruse Hansen, Kjeld Madsen, Bernd Peschke, Nils Langeland Johansen, Michael Ankersen
المصدر: European Journal of Medicinal Chemistry. 34:363-380
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Dipeptide, Stereochemistry, Peptidomimetic, Organic Chemistry, Peptide, General Medicine, Peptide hormone, Amino acid, chemistry.chemical_compound, chemistry, Biochemistry, Growth hormone secretagogue, Drug Discovery, Ipamorelin, GHRP-6
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4664c04f23887695914a35a3bd96a8b6Test
https://doi.org/10.1016/s0223-5234Test(99)80086-5 -
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المؤلفون: Kjeld Madsen, Jesper Lau, Birgit Sehested Hansen, Karin Kramer Nielsen, Thomas Kruse Hansen, Nils Langeland Johansen, Henning Thøgersen, Behrend F. Lundt, Peter H. Andersen, Michael Ankersen, Bernd Peschke, Kirsten Raun
المصدر: Journal of Medicinal Chemistry. 41:3705-3714
مصطلحات موضوعية: Male, Models, Molecular, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Swine, Drug Evaluation, Preclinical, Administration, Oral, Biological Availability, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, Oral administration, Internal medicine, Drug Discovery, medicine, Animals, Potency, Structure–activity relationship, Ipamorelin, Molecular Mimicry, Hormones, Rats, Bioavailability, Endocrinology, chemistry, Growth Hormone, Pituitary Gland, Injections, Intravenous, Molecular Medicine, Female, Oligopeptides, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f483c6cf8fe3143ed56face8c2eed8Test
https://doi.org/10.1021/jm980197uTest -
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المصدر: Bioorganic & Medicinal Chemistry Letters. 7:1969-1972
مصطلحات موضوعية: chemistry.chemical_classification, Dipeptide, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Peptide, Tripeptide, Peptide hormone, Growth hormone, Biochemistry, Chemical synthesis, In vitro, chemistry.chemical_compound, Drug Discovery, Molecular Medicine, Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::879e5527a17bc21d3d60917a79d089cfTest
https://doi.org/10.1016/s0960-894xTest(97)00348-x -
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المؤلفون: Kjeld Madsen, Nils Langeland Johansen, Rosario González-Muñiz, Ibon Alkorta, Henning Thøgersen, Peter D. Suzdak, M. Teresa García-López, M. José Domínguez, Rosario Herranz
المصدر: Letters in Peptide Science. 1:269-276
مصطلحات موضوعية: Steric effects, chemistry.chemical_compound, Dipeptide, Indolizidines, Molecular model, chemistry, Stereochemistry, Diastereomer, Peptide bond, Moiety, Indolizidine, Biochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::dd9f08b60d75ce8581a3ee7be0b849f2Test
https://doi.org/10.1007/bf00119767Test