المؤلفون: Joely A. Kellard, Nils J.G. Rorsman, Thomas G. Hill, Sarah L. Armour, Martijn van de Bunt, Patrik Rorsman, Jakob G. Knudsen, Linford J.B. Briant

المصدر: Molecular Metabolism, Vol 40, Iss , Pp 101021- (2020)

مصطلحات موضوعية: Diabetes, High fat diet, Islet of Langerhans, Alpha cell, Insulin tolerance, Hyperglucagonemia, Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2212877820300958Test; https://doaj.org/toc/2212-8778Test

الوصول الحر: https://doaj.org/article/ad9a94c5162e4167af86f21b28811f7fTest

المؤلفون: Linford J.B. Briant, Michael S. Dodd, Margarita V. Chibalina, Nils J.G. Rorsman, Paul R.V. Johnson, Peter Carmeliet, Patrik Rorsman, Jakob G. Knudsen

المصدر: Cell Reports, Vol 23, Iss 11, Pp 3300-3311 (2018)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124718307812Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/5968a2edf07a4115802dca31633e2c1cTest

المؤلفون: Julie Adam, Reshma Ramracheya, Margarita V. Chibalina, Nicola Ternette, Alexander Hamilton, Andrei I. Tarasov, Quan Zhang, Eduardo Rebelato, Nils J.G. Rorsman, Rafael Martín-del-Río, Amy Lewis, Gizem Özkan, Hyun Woong Do, Peter Spégel, Kaori Saitoh, Keiko Kato, Kaori Igarashi, Benedikt M. Kessler, Christopher W. Pugh, Jorge Tamarit-Rodriguez, Hindrik Mulder, Anne Clark, Norma Frizzell, Tomoyoshi Soga, Frances M. Ashcroft, Andrew Silver, Patrick J. Pollard, Patrik Rorsman

المصدر: Cell Reports, Vol 20, Iss 13, Pp 3135-3148 (2017)

مصطلحات موضوعية: fumarate hydratase, β cell, diabetes, fumarate, glucose metabolism, hyperglycemia, insulin, mouse model, pH, succination, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211124717312354Test; https://doaj.org/toc/2211-1247Test

الوصول الحر: https://doaj.org/article/05d52d7c48f340449106e32e0dd4ebf7Test

المؤلفون: Patrik Rorsman, Martijn van de Bunt, Linford J.B. Briant, Jakob G. Knudsen, Joely A. Kellard, Sarah L. Armour, Nils J.G. Rorsman, Thomas G. Hill

المصدر: Kellard, J A, Rorsman, N J G, Hill, T G, Armour, S L, van de Bunt, M, Rorsman, P, Knudsen, J G & Briant, L J B 2020, ' Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet ', Molecular Metabolism, vol. 40, 101021 . https://doi.org/10.1016/j.molmet.2020.101021Test
Molecular Metabolism, Vol 40, Iss, Pp 101021-(2020)
Molecular Metabolism

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Alpha cell, Mice, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Insulin, 0303 health sciences, geography.geographical_feature_category, Chemistry, High fat diet, digestive, oral, and skin physiology, Diabetes, Glucagon secretion, Insulin tolerance, Islet, Somatostatin, Female, Intracellular, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, Somatostatin-Secreting Cells, lcsh:Internal medicine, endocrine system, 030209 endocrinology & metabolism, Diet, High-Fat, Hyperglucagonemia, Glucagon, Article, 03 medical and health sciences, Islets of Langerhans, Diabetes mellitus, Internal medicine, medicine, Animals, Secretion, lcsh:RC31-1245, Molecular Biology, Islet of Langerhans, 030304 developmental biology, geography, Cell Biology, medicine.disease, Mice, Inbred C57BL, CTL, 030104 developmental biology, Endocrinology, Glucose, Glucagon-Secreting Cells, Delta cell, Paracrine, Blood sugar regulation, Calcium

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c940e657d80c41fbb31501c12eb4a5Test
https://curis.ku.dk/ws/files/244277596/Reduced_somatostatin_signalling_leads_to_hypersecretion_of_glucagon_in_mice_fed_a_high_fat_diet.pdfTest

المؤلفون: Matthew Harris, Joana Real, Margarita V. Chibalina, Anna Benrick, Laura J. McCulloch, Caroline Miranda, Davide Basco, Frank Reimann, Graham Ladds, Reshma Ramracheya, A Clark, Belén Chanclón, Joely A. Kellard, P Rorsman, Claudia Guida, Nils J.G. Rorsman, M Shigeto, Bernard Thorens, Ho Yan Yeung, Ingrid Wernstedt Asterholm

مصطلحات موضوعية: 0303 health sciences, medicine.medical_specialty, geography, geography.geographical_feature_category, Chemistry, Insulin, medicine.medical_treatment, Glucagon secretion, 030209 endocrinology & metabolism, Islet, Glucagon, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, Knockout mouse, medicine, Receptor, Antagonism, Glucagon receptor, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d18310a2dc2d5bdfd2ce0d444729c4b0Test
https://doi.org/10.1101/785667Test

المؤلفون: Juha T. Huiskonen, Phillip J. Stansfeld, Rebecca Sitsapesan, Chau M Ta, A. Tessitore, Nils J.G. Rorsman, Leela Shrestha, A. Chu, Paolo Tammaro, Robin A. Corey, Ashley C. W. Pike, Maria Falzone, Qinrui Wang, C.A. Shintre, S.M.M. Mukhopadhyay, J. Love, Elisabeth P. Carpenter, Thomas D. Newport, S.R. Bushell, Alessio Accardi, N.A. Burgess-Brown

مصطلحات موضوعية: 0303 health sciences, Ataxia, Phospholipid scramblase, Chemistry, Endoplasmic reticulum, medicine.disease, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Membrane, Cytoplasm, medicine, Spinocerebellar ataxia, medicine.symptom, 030217 neurology & neurosurgery, Intracellular, 030304 developmental biology, Chloride channel activity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbf7c2f4dd063457583165b98a8a451Test
https://doi.org/10.1101/447417Test

المؤلفون: Makoto Shigeto, Manuela Zaccolo, Reshma Ramracheya, Antony Galione, William Sones, Thomas Reinbothe, Benoit Hastoy, Rudi Vennekens, Elisa Vergari, Cathryn Weston, Graham Ladds, Viacheslav O. Nikolaev, Chae Young Cha, Masashi Katsura, Nils J.G. Rorsman, Andrei I. Tarasov, Patrik Rorsman, Paul Johnson, Julia Gorelik, Koenraad Philippaert, Margarita V. Chibalina, Albert Salehi, Kohei Kaku

المساهمون: Ladds, Graham [0000-0001-7320-9612], Apollo - University of Cambridge Repository

مصطلحات موضوعية: MOUSE ISLETS, endocrine system, medicine.medical_specialty, medicine.medical_treatment, Immunology, TYPE-2 DIABETIC-PATIENTS, TRPM Cation Channels, Research & Experimental Medicine, Biology, GLUCOSE, Membrane Potentials, Mice, Tolbutamide, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Internal medicine, Insulin Secretion, medicine, Animals, Humans, Insulin, Channel blocker, PROTEIN-KINASE-C, Protein Kinase C, Protein kinase C, Mice, Knockout, Science & Technology, GLUCAGON-LIKE PEPTIDE-1, Ion Transport, Isradipine, Pancreatic islets, digestive, oral, and skin physiology, Depolarization, 11 Medical And Health Sciences, General Medicine, CATION CHANNEL TRPM4, Insulin oscillation, Endocrinology, medicine.anatomical_structure, Medicine, Research & Experimental, RAT ISLETS, B-CELLS, PANCREATIC BETA-CELLS, Tetradecanoylphorbol Acetate, Life Sciences & Biomedicine, hormones, hormone substitutes, and hormone antagonists, ACTION-POTENTIALS, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce9c8d589f091227aa5ae7d0286bf35Test
https://ora.ox.ac.uk/objects/uuid:bf20aef5-debd-4768-9a1e-76c25351ea79Test

المؤلفون: Quan Zhang, Reshma Ramracheya, Patrik Rorsman, Nils J.G. Rorsman

مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Alpha (ethology), Biology, Glucagon, Exocytosis, Alpha cell, KATP Channels, Internal medicine, Insulin-Secreting Cells, Internal Medicine, medicine, Diabetes Mellitus, Animals, Humans, Hypoglycemic Agents, Voltage-dependent calcium channel, Depolarization, Potassium channel, Endocrinology, Sulfonylurea Compounds, Glucagon-Secreting Cells, Sulfonylurea receptor, Calcium Channels, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7942ea43ab2aed969769342f8bdefc24Test
https://doi.org/10.1007/s00125-014-3279-8Test

المؤلفون: Andrei I. Tarasov, Anna L. Gloyn, Carolina Lahmann, Mary E. Travers, Quan Zhang, Frances M. Ashcroft, Jonathan N. Walker, Melissa F. Brereton, Juris Galvanovskis, Albert Salehi, Fiona M. Gribble, Patrik Rorsman, Reshma Ramracheya, Paul Johnson, Orit Braha, Alejandro González, Frank Reimann, Nils J.G. Rorsman, Martin Bengtsson, Lukas N. Groschner, Stephan C. Collins, Matthias Braun

المصدر: Cell Metabolism

مصطلحات موضوعية: medicine.medical_specialty, endocrine system, Patch-Clamp Techniques, Physiology, Tolbutamide, 030209 endocrinology & metabolism, Type 2 diabetes, Carbohydrate metabolism, Biology, Hypoglycemia, In Vitro Techniques, Glucagon, Exocytosis, Article, Membrane Potentials, 03 medical and health sciences, Mice, 0302 clinical medicine, Adenosine Triphosphate, KATP Channels, Internal medicine, Diabetes mellitus, medicine, Animals, Humans, Potassium Channels, Inwardly Rectifying, Molecular Biology, 030304 developmental biology, 0303 health sciences, Glucagon secretion, Cell Biology, medicine.disease, Tissue Donors, 3. Good health, Endocrinology, Glucose, Diabetes Mellitus, Type 2, Glucagon-Secreting Cells, Mutation, Blood sugar regulation, Calcium, Calcium Channels, hormones, hormone substitutes, and hormone antagonists, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01792c8f9bdc775db8a28c69430086cTest
https://pubmed.ncbi.nlm.nih.gov/24315372Test