المؤلفون: Schaafsma, D, Gosens, R, Bos, IST, Meurs, H, Zaagsma, J, Nelemans, SA

المصدر: Schaafsma , D , Gosens , R , Bos , IST , Meurs , H , Zaagsma , J & Nelemans , SA 2005 , ' Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction ' , Respiratory Research , vol. 6 , no. 1 , 85 . https://doi.org/10.1186/1465-9921-6-85Test

مصطلحات موضوعية: CA2+ SENSITIZATION, HYPERRESPONSIVE RATS, PROSTANOID RECEPTORS, MAP KINASE, CELLS, PHENOTYPE, TRACHEAL, PROLIFERATION, 8-ISO-PGE(2), INHIBITION

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/d112f804-cd3f-40ab-adcd-6b059caf8e88Test

الإتاحة: https://doi.org/10.1186/1465-9921-6-85Test
https://hdl.handle.net/11370/d112f804-cd3f-40ab-adcd-6b059caf8e88Test
https://research.rug.nl/en/publications/d112f804-cd3f-40ab-adcd-6b059caf8e88Test
https://pure.rug.nl/ws/files/61237356/Role_of_contractile_prostaglandins_and_Rho_kinase_in_growth_factor_induced_airway_smooth_muscle_contraction.pdfTest

المؤلفون: Schaafsma, D, Boterman, M, de Jong, A-M, Hovens, I., Penninks, JM, Nelemans, SA, Meurs, H, Zaagsma, J

المصدر: Schaafsma , D , Boterman , M , de Jong , A-M , Hovens , I , Penninks , JM , Nelemans , SA , Meurs , H & Zaagsma , J 2006 , ' Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction ' , British Journal of Pharmacology , vol. 147 , no. 7 , pp. 737-743 . https://doi.org/10.1038/sj.bjp.0706665Test

مصطلحات موضوعية: Rho-kinase, airway smooth muscle, contraction, Ca2+-mobilization, Ca2+-influx, Ca2+-sensitization, bovine, muscarinic agonists, muscarinic receptors, Y-27632, PHOSPHOINOSITIDE METABOLISM, MYOSIN PHOSPHORYLATION, CA2+ SENSITIVITY, CELLS, SENSITIZATION, MOBILIZATION, ACTIVATION, GENERATION, SUBTYPE, CALCIUM

العلاقة: https://research.rug.nl/en/publications/a39853eb-f248-45d0-a10c-3a23d8ca9366Test

الإتاحة: https://doi.org/10.1038/sj.bjp.0706665Test
https://hdl.handle.net/11370/a39853eb-f248-45d0-a10c-3a23d8ca9366Test
https://research.rug.nl/en/publications/a39853eb-f248-45d0-a10c-3a23d8ca9366Test

المؤلفون: Gosens, R, Schaafsma, D, Nelemans, SA, Halayko, AJ

المصدر: Gosens , R , Schaafsma , D , Nelemans , SA & Halayko , AJ 2006 , ' Rho-kinase as a drug target for the treatment of airway hyperresponsiveness in asthma ' , Mini-Reviews in Medicinal Chemistry , vol. 6 , no. 3 , pp. 339-348 .

مصطلحات موضوعية: airway remodelling, airway smooth muscle, airway inflammation, Y-27632, fasudil, SMOOTH-MUSCLE-CELLS, EXTRACELLULAR-MATRIX PROTEINS, POTENTIAL THERAPEUTIC TARGET, SERUM RESPONSE FACTOR, GENE-EXPRESSION, CA2+ SENSITIZATION, ACTIN POLYMERIZATION, CYSTEINYL LEUKOTRIENES, NUCLEAR TRANSLOCATION, INTRAOCULAR-PRESSURE

العلاقة: https://research.rug.nl/en/publications/63872611-16b2-4204-b912-1b37d22a3690Test

الإتاحة: https://hdl.handle.net/11370/63872611-16b2-4204-b912-1b37d22a3690Test
https://research.rug.nl/en/publications/63872611-16b2-4204-b912-1b37d22a3690Test

المؤلفون: Schaafsma, D, Zuidhof, AB, Nelemans, SA, Zaagsma, J, Meurs, H

المصدر: Schaafsma , D , Zuidhof , AB , Nelemans , SA , Zaagsma , J & Meurs , H 2006 , ' Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations ' , European Journal of Pharmacology , vol. 531 , no. 1-3 , pp. 145-150 . https://doi.org/10.1016/j.ejphar.2005.12.043Test

مصطلحات موضوعية: airway hyperresponsiveness, airway smooth muscle, allergy, asthma, contraction, ovalbumin, passive sensitization, Rho-kinase, Y-27632, (guinea pig), CA2+ SENSITIZATION, LEUKOTRIENE C-4, GUINEA-PIGS, MAST-CELLS, TRACHEAL, HISTAMINE, RESPONSIVENESS

العلاقة: https://research.rug.nl/en/publications/405abc31-bbe2-4166-ad39-6917e8021185Test

الإتاحة: https://doi.org/10.1016/j.ejphar.2005.12.043Test
https://hdl.handle.net/11370/405abc31-bbe2-4166-ad39-6917e8021185Test
https://research.rug.nl/en/publications/405abc31-bbe2-4166-ad39-6917e8021185Test

المؤلفون: Gosens, R, Grootte Bromhaar, MM, Tonkes, A, Schaafsma, D, Zaagsma, J, Nelemans, SA, Meurs, H

المصدر: Gosens , R , Grootte Bromhaar , MM , Tonkes , A , Schaafsma , D , Zaagsma , J , Nelemans , SA & Meurs , H 2004 , ' Muscarinic M-3 receptor-dependent regulation of airway smooth muscle contractile phenotype ' , British Journal of Pharmacology , vol. 141 , no. 6 , pp. 943-950 . https://doi.org/10.1038/sj.bjp.0705709Test

مصطلحات موضوعية: airway smooth muscle, contractility, phenotype, bovine, muscarinic M-3 receptor, phosphatidylinositol 3-kinase, mitogen activated protein kinase, protein kinase C, proliferation, SERUM RESPONSE FACTOR, IN-VITRO, KINASE-B, CELL PROLIFERATION, GENE-EXPRESSION, GROWTH-FACTORS, M2 RECEPTORS, GUINEA-PIGS, ACTIVATION, MODULATION

العلاقة: https://research.rug.nl/en/publications/4ea9b0c7-d1d1-4722-8f2d-bcf9947f9303Test

الإتاحة: https://doi.org/10.1038/sj.bjp.0705709Test
https://hdl.handle.net/11370/4ea9b0c7-d1d1-4722-8f2d-bcf9947f9303Test
https://research.rug.nl/en/publications/4ea9b0c7-d1d1-4722-8f2d-bcf9947f9303Test

المؤلفون: Oostendorp, J, Obels, PP, Nelemans, SA, Zaagsma, J

المصدر: Oostendorp , J , Obels , PP , Nelemans , SA & Zaagsma , J 2004 , ' Modulation of beta(2)- and beta(3)-adrenoceptor-mediated relaxation of rat oesophagus smooth muscle by protein kinase C ' , European Journal of Pharmacology , vol. 495 , no. 1 , pp. 75-81 . https://doi.org/10.1016/j.ejphar.2004.05.008Test ; ISSN:0014-2999

مصطلحات موضوعية: oesophagus muscularis mucosae, 2-adrenoceptor, 3-adrenoceptor, protein kinase C, receptor cross-talk, BETA-ADRENERGIC-RECEPTOR, MEDIATING RELAXATION, MUSCULARIS MUCOSAE, DESENSITIZATION, PHOSPHORYLATION, STIMULATION

الإتاحة: https://doi.org/10.1016/j.ejphar.2004.05.008Test
http://hdl.handle.net/11370/e06eaca0-b762-4b1a-b0bf-7e1fbe6b65a9Test
https://research.rug.nl/en/publications/modulation-of-beta2-and-beta3adrenoceptormediated-relaxation-of-rat-oesophagus-smooth-muscle-by-protein-kinase-cTest(e06eaca0-b762-4b1a-b0bf-7e1fbe6b65a9).html

المؤلفون: Gosens, R, Nelemans, SA, Bromhaar, MMG, Meurs, H, Zaagsma, J

المصدر: Gosens , R , Nelemans , SA , Bromhaar , MMG , Meurs , H & Zaagsma , J 2003 , ' Insulin induces a hypercontractile airway smooth muscle phenotype ' , European Journal of Pharmacology , vol. 481 , no. 1 , pp. 125-131 . https://doi.org/10.1016/j.ejphar.2003.08.081Test

مصطلحات موضوعية: insulin, air-way smooth muscle, phenotype, asthma, diabetes, TYPE-1 DIABETES-MELLITUS, M-2 MUSCARINIC RECEPTORS, PROOF-OF-CONCEPT, CELLS, CHILDREN, MITOGENESIS, SYMPTOMS, TRACHEA, KINASE, SERUM

العلاقة: https://research.rug.nl/en/publications/8f609d1a-20ec-48eb-94ed-cb4e41b2ec15Test

الإتاحة: https://doi.org/10.1016/j.ejphar.2003.08.081Test
https://hdl.handle.net/11370/8f609d1a-20ec-48eb-94ed-cb4e41b2ec15Test
https://research.rug.nl/en/publications/8f609d1a-20ec-48eb-94ed-cb4e41b2ec15Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14637184&dopt=AbstractTest

المؤلفون: Gosens, Reinoud, Nelemans, SA, Bromhaar, MMG, McKay, S, Zaagsma, J, Meurs, H

المصدر: Gosens , R , Nelemans , SA , Bromhaar , MMG , McKay , S , Zaagsma , J & Meurs , H 2003 , ' Muscarinic M-3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle ' , American Journal of Respiratory Cell and Molecular Biology , vol. 28 , no. 2 , pp. 257-262 . https://doi.org/10.1165/rcmb.2002-0128OCTest ; ISSN:1044-1549

مصطلحات موضوعية: PROTEIN-COUPLED RECEPTORS, SIGNAL-REGULATED KINASE, PHOSPHOINOSITIDE METABOLISM, MOLECULAR MECHANISMS, DNA-SYNTHESIS, M2 RECEPTORS, BETA-GAMMA, ACTIVATION, CELLS, PROLIFERATION

الإتاحة: https://doi.org/10.1165/rcmb.2002-0128OCTest
http://hdl.handle.net/11370/c8d96de0-dbea-45da-bde7-47b6a2704502Test
https://research.rug.nl/en/publications/muscarinic-m3receptors-mediate-cholinergic-synergism-of-mitogenesis-in-airway-smooth-muscleTest(c8d96de0-dbea-45da-bde7-47b6a2704502).html

المؤلفون: Filipeanu, CM, Henning, RH, Nelemans, SA, de Zeeuw, D

المصدر: Filipeanu , CM , Henning , RH , Nelemans , SA & de Zeeuw , D 2001 , ' Intracellular angiotensin II : from myth to reality? ' , Journal of the Renin-Angiotensin-Aldosterone System , vol. 2 , no. 4 , pp. 219-226 .

مصطلحات موضوعية: angiotensin II, intracellular effects, angiotensin receptors, signal transduction, RAS, VASCULAR SMOOTH-MUSCLE, CARDIAC MYOCYTES, CELL COMMUNICATION, CONVERTING-ENZYME, CA2+ MOBILIZATION, BINDING PROTEIN, PLASMA-MEMBRANE, AT(1) RECEPTOR, RAT, RENIN

العلاقة: https://research.rug.nl/en/publications/21e976ee-2dee-4075-9852-47c292f7f244Test

الإتاحة: https://hdl.handle.net/11370/21e976ee-2dee-4075-9852-47c292f7f244Test
https://research.rug.nl/en/publications/21e976ee-2dee-4075-9852-47c292f7f244Test

المؤلفون: Filipeanu, CM, Brailoiu, E, Kok, JW, Henning, RH, De Zeeuw, D, Nelemans, SA

المصدر: Filipeanu , CM , Brailoiu , E , Kok , JW , Henning , RH , De Zeeuw , D & Nelemans , SA 2001 , ' Intracellular angiotensin II elicits Ca2+ increases in A7r5 vascular smooth muscle cells ' , European Journal of Pharmacology , vol. 420 , no. 1 , pp. 9-18 .

مصطلحات موضوعية: angiotensin II, intracellular, liposome, Ca2+ influx, Ca2+ release, Ins(1,4,5)P-3, A7r5 cell, DDT1 MF-2 CELLS, AT(1) RECEPTOR, RAT AORTA, CARDIAC MYOCYTES, G-PROTEINS, RELEASE, SYSTEM, LOCALIZATION, GENERATION, HEART

العلاقة: https://research.rug.nl/en/publications/14c11433-8270-4beb-89ea-71ecb198628fTest

الإتاحة: https://hdl.handle.net/11370/14c11433-8270-4beb-89ea-71ecb198628fTest
https://research.rug.nl/en/publications/14c11433-8270-4beb-89ea-71ecb198628fTest