المؤلفون: Meredith J. Layton, Natalie K. Rynkiewicz, Ivan Ivetac, Kristy A. Horan, Christina A. Mitchell, Wayne A. Phillips

المصدر: Bioscience Reports, Vol 34, Iss 2, p e00104 (2014)

مصطلحات موضوعية: Cdc42, microinjection, mutation, oncogene, PI3K, PIK3CA, Life, QH501-531, Microbiology, QR1-502

وصف الملف: electronic resource

العلاقة: http://www.bioscirep.org/bsr/034/e104/bsr034e104.htmTest; https://doaj.org/toc/1573-4935Test

الوصول الحر: https://doaj.org/article/13a6a58a586a41d09586fb2330ddd7f9Test

المؤلفون: Matthew J. Eramo, Helen E. Abud, Lisa M Ooms, Samuel J. Rodgers, Elizabeth V. Nguyen, Sabryn A. Hamila, Natalie K. Rynkiewicz, Absorn Sriratana, Georg Ramm, Genevieve Kerr, Catriona McLean, Viola Oorschot, Ralf B. Schittenhelm, Sherene Loi, Andrew M. Ellisdon, Rajendra Gurung, Christina Anne Mitchell, Clare G Fedele, Antonella Papa, Roger J. Daly, Franco Caramia

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications

مصطلحات موضوعية: Proteomics, 0301 basic medicine, Carcinogenesis, General Physics and Astronomy, medicine.disease_cause, Mice, Breast cancer, 0302 clinical medicine, Phosphatidylinositol Phosphates, Breast, Wnt Signaling Pathway, Late endosome, Multidisciplinary, Chemistry, Wnt signaling pathway, Mechanisms of disease, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Class I Phosphatidylinositol 3-Kinases, Endosome, Science, Antineoplastic Agents, Breast Neoplasms, Endosomes, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Phosphoinositol signalling, Cell Line, Tumor, Lysosome, medicine, Animals, Humans, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Oncogene, Gene Expression Profiling, rab7 GTP-Binding Proteins, General Chemistry, Xenograft Model Antitumor Assays, Phosphoric Monoester Hydrolases, Thiazoles, 030104 developmental biology, Tissue Array Analysis, rab GTP-Binding Proteins, Mutation, Proteolysis, Cancer research, Lysosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2e2bc82108595261d2a16543c76a05Test
https://doaj.org/article/59a5e5fde3fd4918b764c6ce08708383Test

المؤلفون: Roger L. Williams, Sabine Suire, Oscar Vadas, David Oxley, Jonathan Clark, Karen E. Anderson, Natalie K. Rynkiewicz, Eleftherios Karanasios, Phillip T. Hawkins, Len R. Stephens, Daniel M. Collins

المصدر: Sci Signal

مصطلحات موضوعية: Agonist, Gene isoform, Cell type, Neutrophils, medicine.drug_class, Protein subunit, Regulator, Inflammation, Endogeny, Biochemistry, Article, Mice, 03 medical and health sciences, 0302 clinical medicine, Multienzyme Complexes, GTP-Binding Protein gamma Subunits, medicine, Animals, Class Ib Phosphatidylinositol 3-Kinase, Molecular Biology, 030304 developmental biology, G protein-coupled receptor, Mice, Knockout, 0303 health sciences, Chemistry, GTP-Binding Protein beta Subunits, Cell Biology, Cell biology, medicine.symptom, 030217 neurology & neurosurgery, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373d14a377f133a7ce43930caca03701Test
https://doi.org/10.1126/scisignal.aaz4003Test

المؤلفون: Benjamin Grimshaw, Erin Spearing, Delphine Meynard, Luke Bayliss, Audrey Belot, Matthew Wake, Volker Germaschewski, Jemima Paterson, Jonathan Papworth, Igor Theurl, Emily Carter, Anais Palin, Amelie Largounez, Natalie K. Rynkiewicz, Verena Petzer, Alicia Poindron, Robyne Hudson

المصدر: Blood. 134:3532-3532

مصطلحات موضوعية: chemistry.chemical_classification, Ineffective erythropoiesis, biology, medicine.drug_class, Immunology, Ferroportin, Beta thalassemia, Cell Biology, Hematology, medicine.disease, Monoclonal antibody, medicine.disease_cause, Biochemistry, Enzyme, chemistry, Transferrin, Hepcidin, biology.protein, medicine, Cancer research, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::20cca27c4178f1155aa92bc03a2be678Test
https://doi.org/10.1182/blood-2019-124075Test

المؤلفون: Graham G. Giles, Catriona McLean, Karen Chiam, Natalie K. Rynkiewicz, Lisa G. Horvath, James G. Kench, Lisa M Ooms, Clare G Fedele, Christina Anne Mitchell, Ruta Gupta

المصدر: The Prostate. 75:92-102

مصطلحات موضوعية: Oncology, PCA3, medicine.medical_specialty, biology, business.industry, Prostatectomy, Urology, medicine.medical_treatment, Cancer, Chromogranin A, medicine.disease, medicine.anatomical_structure, Prostate, Internal medicine, medicine, biology.protein, Adenocarcinoma, PTEN, business, PI3K/AKT/mTOR pathway

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c0420a368945b2fbd0209c460a2bb33bTest
https://doi.org/10.1002/pros.22895Test

المؤلفون: Sewa Rijal, Shaun Fleming, Nik Cummings, Natalie K Rynkiewicz, Lisa M Ooms, Nhu-Y N Nguyen, Tse-Chieh Teh, Sharon Avery, Julie F McManus, Anthony T Papenfuss, Catriona McLean, Mark Guthridge, Christina A Mitchell, Andrew H Wei

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Hematology, ACUTE MYELOID-LEUKEMIA, INTERNAL TANDEM DUPLICATION, TUMOR-SUPPRESSOR, MUTANT LEVEL, MUTATIONS, PTEN, GENE, PHOSPHORYLATION, CHEMOTHERAPY, ACTIVATION

العلاقة: http://hdl.handle.net/10536/DRO/DU:30132333Test; https://figshare.com/articles/journal_contribution/Inositol_polyphosphate_4-phosphatase_II_INPP4B_is_associated_with_chemoresistance_and_poor_outcome_in_AML/20729362Test

الإتاحة: http://hdl.handle.net/10536/DRO/DU:30132333Test
https://figshare.com/articles/journal_contribution/Inositol_polyphosphate_4-phosphatase_II_INPP4B_is_associated_with_chemoresistance_and_poor_outcome_in_AML/20729362Test

المؤلفون: Mark A. Guthridge, Natalie K. Rynkiewicz, Nik Cummings, Sewa Rijal, Anthony T. Papenfuss, Andrew H. Wei, Tse-Chieh Teh, Julie McManus, Nhu-Y N Nguyen, Catriona McLean, Sharon Avery, Lisa M Ooms, Shaun Fleming, Christina Anne Mitchell

المصدر: Blood. 125(18)

مصطلحات موضوعية: Adult, Adolescent, Daunorubicin, Immunology, Phosphatase, Biology, Biochemistry, Polymorphism, Single Nucleotide, Phosphoinositide Phosphatases, Young Adult, medicine, PTEN, Humans, PI3K/AKT/mTOR pathway, Genetic Association Studies, Aged, Retrospective Studies, Kinase, Gene Expression Regulation, Leukemic, Myeloid leukemia, Cell Biology, Hematology, Middle Aged, medicine.disease, Prognosis, Survival Analysis, Phosphoric Monoester Hydrolases, Leukemia, Leukemia, Myeloid, Acute, Treatment Outcome, Drug Resistance, Neoplasm, Cancer research, biology.protein, Transcriptome, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c53bf15b6487043530b9105406caacTest
https://pubmed.ncbi.nlm.nih.gov/25931577Test

المؤلفون: Natalie K, Rynkiewicz, Clare G, Fedele, Karen, Chiam, Ruta, Gupta, James G, Kench, Lisa M, Ooms, Catriona A, McLean, Graham G, Giles, Lisa G, Horvath, Christina A, Mitchell

المصدر: The Prostate. 75(1)

مصطلحات موضوعية: Adult, Male, Fluorescent Antibody Technique, Prostatic Neoplasms, Middle Aged, Proto-Oncogene Proteins c-met, Survival Analysis, Disease-Free Survival, Phosphoric Monoester Hydrolases, Ki-67 Antigen, Receptors, Androgen, Chromogranin A, Humans, Keratins, Neoplasm Recurrence, Local, Fluorescent Antibody Technique, Indirect, Aged, Proportional Hazards Models

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::97fd1f026a6ac5cfa3d01a4a6318c404Test
https://pubmed.ncbi.nlm.nih.gov/25284366Test

المؤلفون: Christina Anne Mitchell, Ivan Ivetac, Wayne A. Phillips, Natalie K. Rynkiewicz, Meredith J. Layton, Kristy A. Horan

المصدر: Bioscience Reports
Bioscience Reports, Vol 34, Iss 2, p e00104 (2014)

مصطلحات موضوعية: iSH2, inter-SH2, DXMS, deuterium exchange mass spectrometry, Akt, also called PKB (protein kinase B), BH, BCR-homology, 2-ME, 2-mercaptoethanol, lcsh:Life, lcsh:QR1-502, Lipid kinase activity, PI3K, Biochemistry, lcsh:Microbiology, PDGF, platelet-derived growth factor, Receptor tyrosine kinase, Madin Darby Canine Kidney Cells, GAP, GTPase-activating protein, oncogene, GST, glutathione transferase, microinjection, Cdc42, cdc42 GTP-Binding Protein, GFP, green fluorescent protein, Genetics, biology, NA, numerical aperture, HRP, horseradish peroxidase, MDCK, Madin–Darby canine kidney, PS, phosphatidylserine, Cell biology, Protein Transport, PM, plasma membrane, RTK, receptor tyrosine kinase, PI3K, phosphoinositide 3-kinase, PTEN, phosphatase and tensin homologue deleted on chromosome 10, cSH2, C-terminal SH2, Class I Phosphatidylinositol 3-Kinases, PH, pleckstrin homology, Mutation, Missense, Biophysics, P110α, S2, PI, phosphatidylinositol, pY, phosphotyrosine, Membrane Lipids, nSH2, N-terminal SH2, PIP3, phosphoinositide-3,4,5-trisphosphate, Dogs, SH, Src homology, Animals, Humans, PIP2, phosphoinositide-4,5-disphosphate, Molecular Biology, Protein kinase B, Microinjection, PI3K/AKT/mTOR pathway, EGF, epidermal growth factor, Original Paper, Phosphoinositide 3-kinase, Cell Membrane, PIK3CA, Cell Biology, mutation, PTEN, RTK - receptor tyrosine kinase, SH2 - Src homology 2, Subcellular localization, lcsh:QH501-531, Amino Acid Substitution, biology.protein, iMMEC, immortalized mouse mammary epithelial cells, Proto-Oncogene Proteins c-akt, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e57cf0b25e79fca314f084b77ffb8cTest
https://www.bib.irb.hr/1049295Test

المؤلفون: Christina Anne Mitchell, Demis Balamatsias, Natalie K. Rynkiewicz, Heng-Jia Liu

المصدر: Advances in biological regulation. 52(1)

مصطلحات موضوعية: Cancer Research, Genetics, Molecular Medicine, Animals, Guanine Nucleotide Exchange Factors, Humans, Biology, Molecular Biology, Phosphoric Monoester Hydrolases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170ee66f992164ebdd8cfd1f45ef5a4dTest
https://pubmed.ncbi.nlm.nih.gov/21925199Test