نتائج البحث - "Napolitano, Valeria"

1

دورية أكاديمية

Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization

المساهمون: Ciaglia, Tania, Vestuto, Vincenzo, Di Sarno, Veronica, Musella, Simona, Smaldone, Gerardina, Di Matteo, Francesca, Napolitano, Valeria, Miranda, Maria Rosaria, Pepe, Giacomo, Basilicata, Manuela Giovanna, Novi, Sara, Capolupo, Ilaria, Bifulco, Giuseppe, Campiglia, Pietro, Gomez-Monterrey, Isabel, Snoeck, Robert, Andrei, Graciela, Manfra, Michele, Ostacolo, Carmine, Lauro, Gianluigi, Bertamino, Alessia

مصطلحات موضوعية: Antiviral drug, In silico design, In-cell assay, Pepetidomimetc, SARS-CoV-2 cathepsin-L and main protease inhibition

العلاقة: volume:266; firstpage:116128; numberofpages:23; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11563/176735Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85182642774; https://www.elsevier.com/locate/ejmechTest

الإتاحة: https://doi.org/10.1016/j.ejmech.2024.116128Test
https://hdl.handle.net/11563/176735Test
https://www.elsevier.com/locate/ejmechTest

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2

A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells

المؤلفون: Encarnacao, Joao Crispim, Master, 1990, Napolitano, Valeria, Opassi, Giulia, 1988, Danielson, U. Helena, Professor, 1959, Dubin, Grzegorz, Popowicz, Grzegorz M., Munier-Lehmann, Helene, Buijs, Jos, Andersson, Karl, 1972, Bjorkelund, Hanna

المصدر: FEBS Letters. 594(15):2406-2420

مصطلحات موضوعية: binding kinetics, cancer, cell surface receptor, real-time cell-binding assays, receptor internalization, Shiga toxin

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423646Test
https://doi.org/10.1002/1873-3468.13847Test
https://uu.diva-portal.org/smash/get/diva2:1501509/FULLTEXT01.pdfTest

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3

Establishing Trypanosoma cruzi farnesyl pyrophosphatesynthase as a viable target for biosensor driven fragment-based lead discovery

المؤلفون: Opassi, Giulia, 1988, Nordström, Helena, 1974, Lundin, Arne, Napolitano, Valeria, Magari, Francesca, Dzus, Tom, Danielson, U. Helena, Professor, 1959

المصدر: Protein Science. 29(4):991-1003

مصطلحات موضوعية: binding efficiency, Chagas disease, farnesyl pyrophosphate synthase, fragment screening, SPR, Trypanosoma cruzi

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408723Test
https://doi.org/10.1002/pro.3834Test
https://uu.diva-portal.org/smash/get/diva2:1423065/FULLTEXT01.pdfTest

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4

دورية أكاديمية

Development of novel PEX5-PEX14 protein-protein interaction (PPI) inhibitors based on an oxopiperazine template

المؤلفون: Marciniak, Monika, Mróz, Piotr, Napolitano, Valeria, Kalel, Vishal C., Fino, Roberto, Pykacz, Emilia, Schliebs, Wolfgang, Plettenburg, Oliver, Erdmann, Ralf, Sattler, Michael, Popowicz, Grzegorz M., Dawidowski, Maciej

المصدر: European Journal of Medicinal Chemistry 258 (2023) ; European Journal of Medicinal Chemistry

مصطلحات موضوعية: Oxopiperazine, Peptidomimetics, Protein-protein interaction inhibitors, Structure-based drug design, Trypanocidal inhibitors, α-Helical mimetics, ddc:610

العلاقة: ESSN:1768-3254; http://dx.doi.org/10.15488/17278Test; https://www.repo.uni-hannover.de/handle/123456789/17406Test

الإتاحة: https://doi.org/10.15488/17278Test
https://doi.org/10.1016/j.ejmech.2023.115587Test
https://www.repo.uni-hannover.de/handle/123456789/17406Test

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5

دورية أكاديمية

Crystal structure of staphopain C from Staphylococcus aureus

المؤلفون: Magoch, Małgorzata, McEwen, Alastair G., Napolitano, Valeria, Władyka, Benedykt, Dubin, Grzegorz

مصطلحات موضوعية: Staphylococcus aureus, staphopain, ScpA2, virulence factor, cysteine protease, X-ray crystallography

العلاقة: Molecules, T. 28, nr 11; https://ruj.uj.edu.pl/xmlui/handle/item/312355Test

الإتاحة: https://doi.org/10.3390/molecules28114407Test
https://ruj.uj.edu.pl/xmlui/handle/item/312355Test

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النص الكامل

6

دورية أكاديمية

Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide

المؤلفون: Troisi, Romualdo, Napolitano, Valeria, Rossitto, Emanuele, Osman, Waleed, Nagano, Masanobu, Wakui, Koji, Popowicz, Grzegorz M, Yoshimoto, Keitaro, Sica, Filomena

المساهمون: AMED, JSPS Transformative Research Areas, SENSHIN Medical Research Foundation, University of Naples Federico II, University of Tokyo, LinkBIO Co. Ltd

المصدر: Nucleic Acids Research ; volume 51, issue 16, page 8880-8890 ; ISSN 0305-1048 1362-4962

الإتاحة: https://doi.org/10.1093/nar/gkad634Test
https://academic.oup.com/nar/article-pdf/51/16/8880/51300601/gkad634.pdfTest

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7

دورية أكاديمية

Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis

المساهمون: Ministero dell’Istruzione, dell’Università e della Ricerca, Associazione Italiana per la Ricerca sul Cancro, Università degli Studi di Napoli Federico II

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 13, page 9201-9222 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c00831Test

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