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Alterations in the diversity, composition and function of the gut microbiota in Uyghur individuals with sarcopenia

التفاصيل البيبلوغرافية
العنوان: Alterations in the diversity, composition and function of the gut microbiota in Uyghur individuals with sarcopenia
المؤلفون: Qiuxi Zhang, Xin Li, Ting Huang, Shuang Zhang, Kunchen Teng, Namuna Rousitemu, Ting Lan, Youfeng Wen
المصدر: Experimental Gerontology, Vol 187, Iss , Pp 112376- (2024)
بيانات النشر: Elsevier, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
LCC:Biology (General)
مصطلحات موضوعية: Sarcopenia, Gut microbiota, Muscle mass, Xinjiang Uyghur, Medicine, Biology (General), QH301-705.5
الوصف: Background: Research on the gut microbiota has emerged as a new direction for understanding pathophysiologic changes in diseases associated with aging, such as sarcopenia. Several studies have shown that there are differences in the gut microbiota between individuals with sarcopenia and without sarcopenia. However, these differences are not consistent across regions and ethnic groups, and additional research is needed. Methods: In this study, we collected fresh fecal samples from 31 Uyghur individuals with sarcopenia and 31 healthy controls. We used 16S rRNA sequencing to obtain fecal base sequences and analyzed the diversity, composition and function of the gut microbiota. Results: There was no significant difference in alpha diversity between the sarcopenia group and the healthy control group (P > 0.05). There was a significant difference in beta diversity between the groups (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1873-6815
العلاقة: http://www.sciencedirect.com/science/article/pii/S0531556524000184Test; https://doaj.org/toc/1873-6815Test
DOI: 10.1016/j.exger.2024.112376
الوصول الحر: https://doaj.org/article/e24ced36b1af4d8f9302c81b6dcf85aeTest
رقم الانضمام: edsdoj.24ced36b1af4d8f9302c81b6dcf85ae
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:18736815
DOI:10.1016/j.exger.2024.112376