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1دورية أكاديمية
المؤلفون: Yam B. Poudel, Liqi He, Matthew Cox, Qian Zhang, Walter L. Johnson, Qiang Cong, Heng Cheng, Naidu S. Chowdari, Christine Tarby, Andrew F. Donnell, Matthais Broekema, Daniel P. O’Malley, Yong Zhang, Murugaiah A. M. Subbaiah, Boda Vijay Kumar, Lakshumanan Subramani, Bei Wang, Yi-Xin Li, Prasanna Sivaprakasam, David Critton, Dawn Mulligan, Bhupindar Sandhu, Chunshan Xie, Radha Ramakrishnan, Jignesh Nagar, Shailesh Dudhgaonkar, Martins S. Oderinde, Anwar Murtaza, Gary L. Schieven, Arvind Mathur, Ashvinikumar V. Gavai, Gregory Vite, Sanjeev Gangwar
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, mouse whole blood, complete tumor regression, 26 tumor model, based reporter assay, selective tlr7 agonists, novel tlr7 agonists, tlr7 agonists, developed novel, based designs, vitro <, tnfα cytokines, systemic agent, significant secretion, pharmacodynamic studies, mice showed, intravenous route
الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00455.s001Test
https://figshare.com/articles/journal_contribution/Discovery_of_Novel_TLR7_Agonists_as_Systemic_Agent_for_Combination_With_aPD1_for_Use_in_Immuno-oncology/24961448Test -
2دورية أكاديمية
المؤلفون: Prasanna Sivaprakasam (1399360), Ivar McDonald (9610875), Christiana Iwuagwu (3146403), Naidu S. Chowdari (2538496), Kevin M. Peese (1457527), David R. Langley (367086), Heng Cheng (2688691), Michael R. Luzung (2246713), Michael A. Schmidt (2418700), Bin Zheng (45359), Yichen Tan (1942708), Patricia Cho (9537643), Souvik Rakshit (1651654), Thirumalai Lakshminarasimhan (2830316), Sivakrishna Guturi (10124198), Kishorekumar Kanagavel (10124201), Umamaheswararao Kanusu (10124204), Ankita G. Niyogi (10124207), Somprabha Sidhar (10124210), Rajappa Vaidyanathan (2325358), Martin D. Eastgate (1314654), Srikanth Kotapati (1340013), Madhura Deshpande (9610878), Chin Pan (2853359), Pina M. Cardarelli (3110967), Chunshan Xie (3736810), Chetana Rao (8250255), Patrick Holder (1326876), Ganapathy Sarma (9610881), Gregory Vite (2853350), Sanjeev Gangwar (2853356)
مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, site-specific conjugation method, Antibody, Fused Benzodiazepine Hybrid Payloads, N 87, series, lysosomal cleavage, plasma stability, lysosome-cleavable peptide linker, MPB, tetrahydroisoquinoline-fused benzod., ADC, DNA models, cancer cell lines, anti-mesothelin antibody, ring system, payloads, anticancer therapeutics, cancer xenograft model, TBD, DNA-Model-Based Design
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المؤلفون: Michael A. Schmidt, Chunshan Xie, Naidu S. Chowdari, Ankita G. Niyogi, David R. Langley, Heng Cheng, Gregory D. Vite, Sivakrishna Guturi, Rajappa Vaidyanathan, Sanjeev Gangwar, Ivar M. McDonald, Kishorekumar Kanagavel, Yichen Tan, Prasanna Sivaprakasam, Souvik Rakshit, Chin Pan, Umamaheswararao Kanusu, Martin D. Eastgate, Madhura Deshpande, Somprabha Sidhar, Bin Zheng, Christiana I. Iwuagwu, Michael R. Luzung, Ganapathy Sarma, Kevin M. Peese, Thirumalai Lakshminarasimhan, Patrick G. Holder, Pina M. Cardarelli, Patricia Cho, Srikanth Kotapati, Chetana Rao
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: chemistry.chemical_classification, Antibody-drug conjugate, biology, 010405 organic chemistry, medicine.drug_class, Organic Chemistry, Peptide, Monoclonal antibody, 01 natural sciences, Biochemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Drug Discovery, medicine, biology.protein, Antibody, Cytotoxicity, Linker, Conjugate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebc8e44bdde09da681c8a7885776a0fTest
https://doi.org/10.1021/acsmedchemlett.0c00578Test -
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المؤلفون: Prem B. Chanda, Gregory D. Vite, Naidu S. Chowdari, Christopher Gartshore, Dale L. Boger, Anindya Sarkar, Shinji Tadano, Qian Zhang, Jelena Momirov, Sanjeev Gangwar
المصدر: Organic Letters. 22:8714-8719
مصطلحات موضوعية: Stereochemistry, Chemistry, Longest linear sequence, Meayamycin, Organic Chemistry, Total synthesis, Physical and Theoretical Chemistry, Biochemistry, Divergent synthesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::17c615bc98bb2e36e870a5d2769f6bf1Test
https://doi.org/10.1021/acs.orglett.0c03308Test -
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المؤلفون: Rajesh Kishore Kumar Sanku, Qiang Cong, Shrikant Deshpande, Vangipuram S. Rangan, Sanjeev Gangwar, Naidu S. Chowdari, Yam B. Poudel, Chetana Rao, Pina M. Cardarelli, David Passmore, Pavel Strop, Sayumi Yamazoe, Srikanth Kotapati, Gavin Dollinger, Arvind Rajpal
المصدر: Analytical Chemistry. 92:2065-2073
مصطلحات موضوعية: PNGase F, Streptavidin, Immunoconjugates, Chromatography, Resolution (mass spectrometry), Chemistry, 010401 analytical chemistry, Antibodies, Monoclonal, 010402 general chemistry, Mass spectrometry, 01 natural sciences, Mass Spectrometry, 0104 chemical sciences, Analytical Chemistry, body regions, chemistry.chemical_compound, Biotransformation, Liquid chromatography–mass spectrometry, In vivo, Biotinylation, Humans, Chromatography, Liquid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a753351fa822ddb82a31837e9e661039Test
https://doi.org/10.1021/acs.analchem.9b04572Test -
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المؤلفون: Eilene Kwok, Derwin Daniel W, Sanjeev Gangwar, Chin Pan, Chetana Rao, David Passmore, Yichong Wang, Bilal Sufi, David R. Langley, Pina M. Cardarelli, Vangipuram S. Rangan, Shrikant Deshpande, Gregory D. Vite, Naidu S. Chowdari, Prasanna Sivaprakasam
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:466-470
مصطلحات موضوعية: Models, Molecular, Antibody-drug conjugate, Immunoconjugates, Lung Neoplasms, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Anthraquinones, Antineoplastic Agents, Monoclonal antibody, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Enediyne, Humans, Potency, Cytotoxicity, Molecular Biology, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Antibodies, Monoclonal, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Mechanism of action, Cancer research, Molecular Medicine, Drug Screening Assays, Antitumor, medicine.symptom, Linker, Conjugate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefe534a4de749455cd26d286d78d0f6Test
https://doi.org/10.1016/j.bmcl.2018.12.021Test -
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المؤلفون: Johnson Walter Lewis, Sung Mei-Chen, Daniel Menezes, Chin Pan, Gregory D. Vite, Yong Zhang, Shrikant Deshpande, Vangipuram S. Rangan, Madhura Deshpande, Richard Rampulla, Ganapathy Sarma, Prasanna Sivaprakasam, Arvind Rajpal, David R. Langley, Tram N. Huynh, Arvind Mathur, Ivar M. McDonald, Naidu S. Chowdari, Pina M. Cardarelli, Bethanne M. Warrack, Srikanth Kotapati, Yichong Wang, Chetana Rao, David Passmore, Robert A. Mate, Robert M. Borzilleri, Sanjeev Gangwar
المصدر: Journal of medicinal chemistry. 63(22)
مصطلحات موضوعية: Immunoconjugates, Lung Neoplasms, Lysine, Antineoplastic Agents, Apoptosis, G(M1) Ganglioside, Mice, SCID, Pharmacology, GPI-Linked Proteins, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Benzodiazepines, Mice, Structure-Activity Relationship, Pharmacokinetics, Stomach Neoplasms, Tetrahydroisoquinolines, Drug Discovery, Tumor Cells, Cultured, Structure–activity relationship, Animals, Humans, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Dipeptide, Chemistry, Cell growth, Tetrahydroisoquinoline, Antibodies, Monoclonal, Small Cell Lung Carcinoma, Xenograft Model Antitumor Assays, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Drug Design, Mesothelin, Molecular Medicine, Female, Conjugate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92a9ea42e85c4d5cf7895d4d3aa6edcTest
https://pubmed.ncbi.nlm.nih.gov/33155811Test -
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المؤلفون: Christiana I. Iwuagwu, Srikanth Kotapati, Heng Cheng, Arvind Mathur, Yam B. Poudel, David Passmore, Dalton King, Sanjeev Gangwar, Gregory D. Vite, Richard Rampulla, Naidu S. Chowdari
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Drug, biology, 010405 organic chemistry, Chemistry, media_common.quotation_subject, Organic Chemistry, Chemical modification, Uncialamycin, Cleavage (embryo), 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Drug Discovery, biology.protein, Mouse tumor, Antibody, Linker, media_common, Conjugate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cc85a6bcc4813ad9bbe81c5df193f0Test
https://europepmc.org/articles/PMC7667830Test/ -
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المؤلفون: Gregory D. Vite, Pon Saravanakumar, Richard Rampulla, Ramesh Samikannu, Srikanth Kotapati, Vangipuram S. Rangan, Chetana Rao, Mahammed Kaspady, Arvind Mathur, Sanjeev Gangwar, Prakasam Kuppusamy, Madhura Deshpande, Chin Pan, Shrikant Deshpande, Naidu S. Chowdari, Lourdes Thevanayagam, Pirama Nayagam Arunachalam, Yam B. Poudel, Josephine M. Cardarelli
المصدر: Bioorganic & Medicinal Chemistry Letters. 30:126782
مصطلحات موضوعية: Immunoconjugates, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Anthraquinones, Antineoplastic Agents, 01 natural sciences, Biochemistry, Structure-Activity Relationship, In vivo, Drug Discovery, Enediyne, medicine, Humans, Cytotoxicity, Molecular Biology, Protease, 010405 organic chemistry, Chemistry, Organic Chemistry, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Cancer cell, Molecular Medicine, Linker, Conjugate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f8fe85c95806b1da0ef04a482883caTest
https://doi.org/10.1016/j.bmcl.2019.126782Test -
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المؤلفون: Yam B. Poudel, Debashis Mandal, Manas R. Pattanayak, Laxman Pasunoori, Min Lu, Sanjeev Gangwar, Emmanuel N. Pitsinos, Gregory D. Vite, Ruocheng Yu, Kyriacos C. Nicolaou, Naidu S. Chowdari, Jason S. Chen, Akshay A. Shah, James J. Crawford, Hongjun Zhang, Yanping Wang, Chin Pan, Ayesha Nazeer
المصدر: Journal of the American Chemical Society. 138(26)
مصطلحات موضوعية: Annulation, Stereochemistry, Anthraquinones, Antineoplastic Agents, Chemistry Techniques, Synthetic, 010402 general chemistry, 01 natural sciences, Biochemistry, Chemical synthesis, Catalysis, chemistry.chemical_compound, Structure-Activity Relationship, Colloid and Surface Chemistry, Cell Line, Tumor, Enediyne, Structure–activity relationship, Humans, Natural product, 010405 organic chemistry, Chemistry, Enantioselective synthesis, Quinones, Total synthesis, General Chemistry, Combinatorial chemistry, 0104 chemical sciences, Drug development, Drug Design
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a6ccc22c3611a33963f190f8fa9f82Test
https://pubmed.ncbi.nlm.nih.gov/27266267Test