المؤلفون: Matija Hedl, Clara Abraham, Rui Sun

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 249-272 (2021)

مصطلحات موضوعية: 0301 basic medicine, FADD, Fas-associated protein with death domain, MDP, muramyl dipeptide, DR3, death receptor 3, Mice, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Enterococcus faecalis, Cells, Cultured, Original Research, TNF, tumor necrosis factor, IBD, inflammatory bowel disease, TRADD, tumor necrosis factor receptor 1-associated death domain, Gastroenterology, MDM, monocyte-derived macrophages, TACE, tumor necrosis factor converting enzyme, LC3II, light chain 3-II, Autocrine Communication, TNFSF15, TNF superfamily member 15, Receptors, Pattern Recognition, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, Signal transduction, PI3K, phosphoinositide 3-kinase, Crohn’s Disease, TLR, Toll-like receptor, Signal Transduction, Tumor Necrosis Factor Ligand Superfamily Member 15, MALT1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, Primary Cell Culture, NF-κB, nuclear factor-κB, PRR, pattern-recognition receptor, TRAF2, TNF receptor associated factor 2, Biology, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, RIP, receptor-interacting protein kinase, PDK1, pyruvate dehydrogenase kinase 1, Paracrine Communication, Genetics, Escherichia coli, Animals, Humans, Genetic Predisposition to Disease, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Protein kinase A, Receptors, Tumor Necrosis Factor, Member 25, Death domain, Hepatology, NEMO, NF-κB essential modulator, Macrophages, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, BMDM, bone marrow–derived macrophage, siRNA, small interfering RNA, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, JNK, Janus kinase, Cytokine secretion, Pattern Recognition Receptors, Death receptor 3, MAPK, mitogen-activated protein kinase, AIEC, adherent invasive Escherichia coli

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb21b1a8b74b5bc07131da592a5389bdTest
https://doi.org/10.1016/j.jcmgh.2020.08.003Test

المؤلفون: Xi-Xi Li, Zhe Guo, Rongfeng Lan, Huan-Tong Wu, Xiao-Yan Qin, Run-Ze Gu, Yun Yu

المصدر: IBRO Reports
IBRO Reports, Vol 8, Iss, Pp 122-128 (2020)

مصطلحات موضوعية: 0301 basic medicine, Central nervous system, free radical scavenger, Caspase 3, medicine.disease_cause, C1q, complement component 1q, CNS, central nervous system, Neuroprotection, Article, lcsh:RC321-571, TLRs, Toll-like receptors, IL-1α, interleukin 1 alpha, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Edaravone, oxidative stress, TNF-α, tumor necrosis factor alpha, NOS2, nitric oxide synthase 2, Protein kinase B, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, edaravone, GFAP, General Neuroscience, GFAP, glial fibrillary acidic protein, Free radical scavenger, ALS, amyotrophic lateral sclerosis, pro-inflammatory factors, Cell biology, IL-6, interleukin 6, 030104 developmental biology, medicine.anatomical_structure, chemistry, Apoptosis, H2O2, hydrogen peroxide, TNF-α, LPS, lipopolysaccharides, IL-1β, interleukin 1beta, 030217 neurology & neurosurgery, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2752abd56f2a19c3155460aed51985f2Test
http://europepmc.org/articles/PMC7200465Test

المؤلفون: Rui Sun, Clara Abraham

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 673-697 (2020)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Th, T-helper cell, Interleukin-23, 0302 clinical medicine, MDMs, monocyte-derived macrophages, Macrophage, Cells, Cultured, Original Research, GFP, green fluorescent protein, TNF, tumor necrosis factor, Janus kinase 2, IBD, inflammatory bowel disease, biology, Chemistry, TYK2, Tyrosine kinase 2, Gastroenterology, Nitric oxide synthase 2, PI3K, phosphatidylinositol 3-kinase, Cell biology, LC3II, light chain 3-II, STAT, signal transducer and activator of transcription, Interleukin 12, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, JAK, Janus kinase, Infection, NK, natural killer, Intracellular, Crohn’s Disease, PRR, pattern-recognition receptor, Cell Line, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, Immune system, PDK1, pyruvate dehydrogenase kinase 1, Autophagy, Genetics, Humans, Point Mutation, Ulcerative Colitis, IFN, interferon, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Bacteria, Hepatology, Macrophages, Receptors, Interleukin, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, siRNA, small interfering RNA, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, AIEC, adherent invasive Escherichia coli

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad178b92adfc5ec39a7be2f0f160e40Test
https://doi.org/10.1016/j.jcmgh.2020.05.007Test

المؤلفون: Huang, Kai, Zhang, Pan, Zhang, Zhenghao, Youn, Ji Youn, Zhang, Hongchun, Cai, Hua Linda

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: PTGS2, Prostaglandin-endoperoxide synthase 2, TFs, transcription factors, CT, computerized tomography, DAVID, Database for Annotation, Visualization, and Integrated Discovery, MAPK, Mitogen-activated protein kinase, CVA, cough variant asthma, SIRS, systematic inflammatory response syndrome, Nrf2, nuclear factor erythroid 2-related factor 2, SOCS1, suppressor of cytokine signaling 1, Akt, Protein kinase B, 3CLpro, Coronavirus 3-chymotrypsin-like protease, TNF-α, Tumor Necrosis Factor Alpha, HIF-1, Hypoxia-Inducible Factor-1, PI3K, Phosphoinositide 3-kinase, UPLC-DAD-QTOF-MS, Ultra performance liquid chromatography coupled with diode-array detector and quadrupole time-of-flight mass spectrometry, Medicine, Chinese Traditional, RCT, randomized controlled trial, COVID-19, Coronavirus disease 2019, S protein, SARS-CoV-2 spike (S) glycoprotein, TCM, Traditional Chinese Medicine, ACE2, angiotensin converting enzyme 2, Traditional Chinese Medicine (TCM), HSP90AB1, Heat shock protein HSP 90-beta, ICU, intensive care unit, PCT, procalcitonin, PPARG, peroxisome proliferator-activated receptor gamma, Virus Diseases, CRP, C-reactive protein, XBJ, Xuebijing, Lung Cleansing and Detoxifying Decoction (LCDD), IC50, 50% inhibitory concentration, WBC, white blood cell, Xuebijing (XBJ), NCOA2, Nuclear receptor coactivator 2, NFkB, Nuclear factor kappa B, PTGS1, Prostaglandin-endoperoxide synthase 1, JHQG, Jinhua Qinggan granules, KEGG, Kyoto Encyclopedia of Genes and Genomes, Article, WHO, World Health Organization, CASP3, Caspase 3, PPI, protein-protein interaction, TCMID, Traditional Chinese Medicine Integrated Database, COX-2, Cyclooxygenase-2, ROS, reactive oxygen species, ARDS, Acute respiratory distress syndrome, HSBD, Huashibaidu granules, Humans, CCL2, C-C Motif Chemokine Ligand 2, Huashibaidu granules (HSBD), Coronavirus 3-chymotrypsin-like protease (3CLpro), IL-6, Interleukin-6, HNF4A, hepatocyte nuclear factor 4 alpha, GO, gene ontology, HXZQ, Huoxiang Zhengqi dropping pills, ESR, erythrocyte sedimentation rate, Viral infections, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, XFBD, Xuanfeibaidu granules, SARS-CoV-2, IP-10, Interferon gamma-induced protein 10, LCDD, Lung Cleansing and Detoxifying Decoction, COVID-19, BCL2, B-cell lymphoma 2, EGFR, epidermal growth factor receptor, HSP90AA1, Heat shock protein HSP 90-alpha, TP53, Tumor protein p53, COVID-19 Drug Treatment, Lianhua Qingwen capsules (LHQW), COVID, Coronavirus disease, Angiotensin converting enzyme 2 (ACE2), Interleukin-6 (IL-6), miRNAs, micro RNAs, LHQW, Lianhua Qingwen capsules, NOS2, Nitric Oxide Synthase 2 (inducible Nitric Oxide Synthase/iNOS), MCP-1, Monocyte Chemoattractant Protein-1, AGE-RAGE, Advanced glycation end products-Receptor for AGE, Xuanfeibaidu granules (XFBD), IFN-γ, Interferon gamma, Jinhua Qinggan granules (JHQG)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::71220f31b91a2275490401f6bd92afd0Test
http://europepmc.org/articles/PMC8011334Test

المؤلفون: Cesar G. Fraga, Eleonora Cremonini, Elena Daveri, Patricia I. Oteiza, Ana M. Adamo, Steve M. Wood, Angela Mastaloudis, Shelly N. Hester, David A. Mills, Karen M. Kalanetra

المصدر: Redox Biology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Redox Biology, Vol 26, Iss, Pp-(2019)

مصطلحات موضوعية: Clinical Biochemistry, HNE, 4-hydroxynonenal, Medical Biochemistry and Metabolomics, medicine.disease_cause, Occludin, Biochemistry, Oral and gastrointestinal, purl.org/becyt/ford/1 [https], Anthocyanins, chemistry.chemical_compound, HFD, high fat diet, MLC, myosin light chain, INTESTINE, lcsh:QH301-705.5, GLP-2, glucagon-like peptide-2, lcsh:R5-920, NADPH oxidase, biology, Chemistry, NF-kappa B, food and beverages, Pharmacology and Pharmaceutical Sciences, Bioquímica y Biología Molecular, GI, gastrointestinal, TJ, tight junction, OBESITY, FITC, fluorescein isothiocyanate, Goblet Cells, Delphinidin, lcsh:Medicine (General), AC, anthocyanidins, Oxidation-Reduction, CIENCIAS NATURALES Y EXACTAS, Research Paper, Signal Transduction, medicine.medical_specialty, MLCK, myosin light chain kinase, NAFLD, non-alcoholic fatty liver disease, TNFα, tumor necrosis factor alpha, T2D, type 2 diabetes, Diet, High-Fat, Protective Agents, Permeability, Ciencias Biológicas, TEER, transepithelial electrical resistance, Insulin resistance, INFLAMMATION, Downregulation and upregulation, Internal medicine, Complementary and Integrative Health, medicine, ERK1/2, extracellular signal-regulated kinase, PCA, protocatechuic acid, Humans, purl.org/becyt/ford/1.6 [https], NOS2, nitric oxide synthase 2, Metabolic and endocrine, Nutrition, Mucin-2, IFN-γ, interferon gamma, Prevention, Organic Chemistry, FLAVONOIDS, medicine.disease, Endotoxemia, Diet, Gastrointestinal Microbiome, Gastrointestinal Tract, High-Fat, Oxidative Stress, Endocrinology, lcsh:Biology (General), biology.protein, LPS, lipopolysaccharides, Dysbiosis, Biochemistry and Cell Biology, Steatosis, Caco-2 Cells, Digestive Diseases, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24284587a29ec3f38b8a7f6437894169Test
http://europepmc.org/articles/PMC6646927Test

المؤلفون: Horia Muresian, Adrian Manea, A.G. Lazar, Mihaela-Loredana Vlad, Maya Simionescu, Ioana Madalina Fenyo, Simona-Adriana Manea, Monica Raicu

المصدر: Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology

مصطلحات موضوعية: Male, Apolipoprotein E, IL-10, Interleukin -10, Biopsy, RIPA, Radioimmunoprecipitation assay buffer, Clinical Biochemistry, medicine.disease_cause, Biochemistry, SOD, Superoxide dismutase, Epigenesis, Genetic, Mice, Gene expression, CD45/68, Cluster of differentiation 45/68, HDL, High-density lipoprotein, LPS, Lipopolizaharide, lcsh:QH301-705.5, Aorta, Mice, Knockout, chemistry.chemical_classification, lcsh:R5-920, NADPH oxidase, CVD, Cardiovascular disorders, biology, Nox, NADPH oxidase, PBS, Phosphate-buffered saline, Plaque, Atherosclerotic, TNFα, tumor necrosis factor α, NOX1, Epigenetics, Disease Susceptibility, medicine.symptom, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, CD206, Cluster of differentiation 206/manose receptor, TLR2/4, Toll-like receptor 2/4, Inflammation, IFNγ, Interferon gamma, Apolipoproteins E, medicine, Animals, Humans, Histone deacetylase, NADPH, Nicotinamide adenine dinucleotide phosphate (reduced form), Reactive oxygen species, HDAC, Histone deacetylase, Organic Chemistry, DMSO, Dimethyl sulfoxide, NADPH Oxidases, NOS2, Nitric oxide synthase 2, IL-4, Interleukin -4, Cholesterol, LDL, Atherosclerosis, Histone Deacetylase Inhibitors, Disease Models, Animal, Oxidative Stress, EDTA, Ethylenediaminetetraacetic acid disodium salt dehydrate, MMP9, Matrix metalloproteinase 9, Gene Expression Regulation, lcsh:Biology (General), chemistry, biology.protein, Cancer research, LDL, Low-density lipoprotein, Reactive Oxygen Species, Oxidative stress, ROS, Reactive oxygen species, SDS-PAGE, Sodium dodecyl sulfate–polyacrylamide gel electrophoresis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61e6e5181ae1d85fd82cbad6ec18bd5Test
https://doi.org/10.1016/j.redox.2019.101338Test

المؤلفون: Elena Daveri, David A. Mills, Karen M. Kalanetra, Ahmed Bettaieb, Ana M. Adamo, Ziwei Wang, Sidika Karakas, Fawaz G. Haj, Eleonora Cremonini, Patricia I. Oteiza

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Redox Biology
Redox Biology, Vol 14, Iss, Pp 588-599 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Steatosis, Clinical Biochemistry, HNE, 4-hydroxynonenal, (-)-EPICATECHIN, Medical Biochemistry and Metabolomics, Inbred C57BL, Protein oxidation, Biochemistry, Oral and gastrointestinal, Catechin, purl.org/becyt/ford/1 [https], Mice, chemistry.chemical_compound, 0302 clinical medicine, HFD, high fat diet, INTESTINAL PERMEABILITY, NADPH OXIDASE, 2.1 Biological and endogenous factors, Aetiology, Intestinal Mucosa, lcsh:QH301-705.5, GLP-2, glucagon-like peptide-2, lcsh:R5-920, NADPH oxidase, EC, (-)-epicatechin, biology, Chemistry, Liver Disease, digestive, oral, and skin physiology, (-)-Epicatechin, NOX4, food and beverages, Hematology, Pharmacology and Pharmaceutical Sciences, Bioquímica y Biología Molecular, MCP-1, monocyte chemoattractant protein-1, 3. Good health, Intestines, TJ, tight junction, 030220 oncology & carcinogenesis, GTT, glucose tolerance test, lcsh:Medicine (General), CIENCIAS NATURALES Y EXACTAS, Research Paper, INSULIN RESISTANCE, medicine.medical_specialty, MLCK, myosin light chain kinase, TNFα, tumor necrosis factor alpha, T2D, type 2 diabetes, Intestinal permeability, Diet, High-Fat, Protective Agents, Permeability, Ciencias Biológicas, TEER, transepithelial electrical resistance, 03 medical and health sciences, Insulin resistance, Downregulation and upregulation, Internal medicine, ALT, alanine aminotransferase, Complementary and Integrative Health, medicine, ERK1/2, extracellular signal-regulated kinase, Animals, Humans, ENDOTOXEMIA, STEATOSIS, NOS2, nitric oxide synthase 2, purl.org/becyt/ford/1.6 [https], Metabolic and endocrine, Nutrition, ITT, insulin tolerance test, Prevention, Organic Chemistry, medicine.disease, Endotoxemia, Diet, Fatty Liver, Mice, Inbred C57BL, High-Fat, 030104 developmental biology, Endocrinology, lcsh:Biology (General), Apocynin, AMPK, AMP activated protein kinase, biology.protein, LPS, lipopolysaccharides, Biochemistry and Cell Biology, NAFLD, nonalcoholic fatty liver disease, Caco-2 Cells, Digestive Diseases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc190264c88c7fdbcd2050b0149891b9Test
https://www.sciencedirect.com/science/article/pii/S2213231717307668Test

المؤلفون: Angela Everhart, Carol A. Colton, Donna M. Wilcock, Qun Zhao, Marcia N. Gordon, Jennifer E. Lee, Dave Morgan, Joan G. Wilson

المصدر: ASN NEURO
ASN Neuro, Vol 3 (2011)

مصطلحات موضوعية: medicine.medical_treatment, Mrc1, mannose receptor C1, Nitric Oxide Synthase Type II, microglia, AG1, arginase 1, neuroinflammation, Amyloid beta-Protein Precursor, Mice, IL-1β, interleukin 1β, 0302 clinical medicine, Amyloid precursor protein, TGFβ, transforming growth factor β, 0303 health sciences, Microglia, General Neuroscience, Brain, medicine.anatomical_structure, TNFα, tumour necrosis factor α, Disease Progression, LPS, lipopolysaccharide, immunotherapy, AD, Alzheimer's disease, medicine.symptom, Alzheimer's disease, MMP, matrix metalloprotease, Research Article, Genetically modified mouse, Amyloid, BACE1-AS, RT–PCR, reverse transcription–PCR, Inflammation, Mice, Transgenic, S6, Biology, S5, lcsh:RC321-571, 03 medical and health sciences, Alzheimer Disease, APP, amyloid precursor protein, Aβ, amyloid β-peptide, medicine, Animals, Humans, NOS2, nitric oxide synthase 2, SPHK, sphingosine kinase, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, alternative activation, NFT, neurofibrillary tangle, 030304 developmental biology, Interleukin-6, Tumor Necrosis Factor-alpha, Immunotherapy, medicine.disease, MR, mannose receptor, WT, wild-type, Disease Models, Animal, amyloid deposition, Immunology, biology.protein, Neurology (clinical), 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c9d5e0aee05b524069607d962a18deTest
https://pubmed.ncbi.nlm.nih.gov/21995345Test

المؤلفون: Sergey Kalinin, Paul E. Polak, Shao Xia Lin, Anthony Sharp, Cinzia Dello Russo, Lucia Lisi, Douglas L. Feinstein, Guy L. Weinberg

المصدر: ASN Neuro, Vol 3 (2011)
Scopus-Elsevier
ASN NEURO

مصطلحات موضوعية: Lipopolysaccharide, IκBα, inhibitory κBα, Dimethyl Fumarate, Anti-Inflammatory Agents, multiple sclerosis, MSNF-κB, multiple sclerosisi, nuclear factor κB, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Fumarates, Inducer, glutathione, Cells, Cultured, 0303 health sciences, DMEM, Dulbecco's modified Eagle's medium, LDH, lactate dehydrogenase, biology, Dimethyl fumarate, General Neuroscience, nitric oxide synthase 2 (NOS2), HO-1, haem oxygenase-1, NF-kappa B, Nitric oxide synthase 2, 3. Good health, glial cells, Biochemistry, EAEEMSA, experimental autoimmune encephalomyelitiselectrophoretic mobility-shift assay, TNFα, tumour necrosis factor α, LPS, lipopolysaccharide, HSP32, heat-shock protein 32, medicine.symptom, LI, LPS at 1 μg/ml plus IFNγ at 20 units/ml, Immunosuppressive Agents, Inflammation, Research Article, DMF, dimethyl fumarate, Settore BIO/14 - FARMACOLOGIA, GSHs, GSH synthetase, NF-E2-Related Factor 2, S7, IFNγ, interferon γ, BSO, buthionine-sulfoximine, ZnPP, zinc protoporphyrin IX, Nrf2, nuclear factor-erythroid 2 p45 subunit-related factor 2, lcsh:RC321-571, GSHp, GSH peroxidase, 03 medical and health sciences, medicine, Animals, Humans, RNA, Messenger, NOS2, nitric oxide synthase 2, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, 030304 developmental biology, Glutathione, NFKB1, Molecular biology, IL, interleukin, Rats, GSHr, GSH reductase, IκBα, chemistry, inflammation, Astrocytes, biology.protein, FCS, fetal calf serum, Neurology (clinical), qPCR, quantitative PCR, FAE, fumaric acid ester, Heme Oxygenase-1, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caed04029f035eab49988895d3e4a83bTest
https://doaj.org/article/60cddea7fed64cdb8862865866aa3fdcTest