Brain/MINDS beyond human brain MRI project: A protocol for multi-level harmonization across brain disorders throughout the lifespan
| العنوان: | Brain/MINDS beyond human brain MRI project: A protocol for multi-level harmonization across brain disorders throughout the lifespan |
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| المؤلفون: | Takashi Hanakawa, Junichiro Yoshimoto, Katsutoshi Murata, Ayumu Yamashita, Michiko Asano, Matthew F. Glasser, Masaki Fukunaga, Joonas A. Autio, Atsushi Miyazaki, David C. Van Essen, Norihide Maikusa, Takuya Hayashi, Tomohisa Okada, Norihiro Sadato, Brain, Kentaro Morita, Toshiyuki Araki, Yasumasa Okamoto, Kiyoto Kasai, Yuta Urushibata, Toshihiko Aso, Okito Yamashita, Akiko Uematsu, Megumi Maruyama, Shinsuke Koike, Hiroki Togo, Naohiro Okada, Takayuki Ose, Saori C. Tanaka, Mitsuo Kawato |
| المصدر: | NeuroImage : Clinical NeuroImage: Clinical, Vol 30, Iss, Pp 102600-(2021) |
| بيانات النشر: | Elsevier BV, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | AMED, Japan Agency for Medical Research and Development, MSM, multi-modal surface matching, GLMM, general linear mixed model, MDD, major depressive disorder, PEF, premotor eye field, T1w, T1-weighted, 0302 clinical medicine, ADNI, Alzheimer’s Disease Neuroimaging Initiative, GLM, general linear model, CRHD, Connectome Related to Human Disease, DWI, diffusion-weighted imaging, HARP, Harmonization protocol, Prospective Studies, BPD, bipolar disorder, HARP, Brain Diseases, Human Connectome Project, medicine.diagnostic_test, 05 social sciences, Brain, Regular Article, Human brain, Magnetic Resonance Imaging, TS, traveling subject, medicine.anatomical_structure, Neurology, MCI, mild cognitive impairment, DALYs, disability-adjusted life years, Connectome, PPMI, Parkinson's Progression Markers Initiative, Multi-site study, Traveling subjects, medicine.medical_specialty, ASD, autism spectrum disorder, MNI, Montreal Neurological Institute, Cognitive Neuroscience, Computer applications to medicine. Medical informatics, Longevity, R858-859.7, Harmonization, AD, Alzheimer’s disease, 050105 experimental psychology, 03 medical and health sciences, Physical medicine and rehabilitation, Neuroimaging, NODDI, nerite orientation and density imaging, HCP-style brain imaging, T2w, T2-weighted, medicine, Humans, 0501 psychology and cognitive sciences, Radiology, Nuclear Medicine and imaging, PSL, peri-sylvian language, RC346-429, Brain/MINDS Beyond, Strategic International Brain Science Research Promotion Program, STS, superior temporal sulcus, ComputingMethodologies_COMPUTERGRAPHICS, PD, Parkinson’s disease, Protocol (science), business.industry, CIFTI, Connectivity Informatics Technology Initiative, DecNef, Decoded Neurofeedback, Magnetic resonance imaging, Harmonization protocol, QC, quality control, FEF, frontal eye field, ABCD, Adolescent Brain Cognitive Development, Neurology. Diseases of the nervous system, HCP, Human Connectome Project, rsfMRI, resting-state functional MRI, Neurology (clinical), Psychiatric disorders, business, MRI, magnetic resonance imaging, Neurological disorders, 030217 neurology & neurosurgery |
| الوصف: | Highlights • The Brain/MINDS beyond project plans to collect multi-site/scanner brain MRI data. • Prospective harmonization of MRI was achieved by standardizing scanning protocols. • The preliminary data showed moderate reliability of brain connectome data. • Completing traveling subject plan will allow robust statistical harmonization. • Scanning protocols are publicly available and data will also be shared by 2024. Psychiatric and neurological disorders are afflictions of the brain that can affect individuals throughout their lifespan. Many brain magnetic resonance imaging (MRI) studies have been conducted; however, imaging-based biomarkers are not yet well established for diagnostic and therapeutic use. This article describes an outline of the planned study, the Brain/MINDS Beyond human brain MRI project (BMB-HBM, FY2018 ~ FY2023), which aims to establish clinically-relevant imaging biomarkers with multi-site harmonization by collecting data from healthy traveling subjects (TS) at 13 research sites. Collection of data in psychiatric and neurological disorders across the lifespan is also scheduled at 13 sites, whereas designing measurement procedures, developing and analyzing neuroimaging protocols, and databasing are done at three research sites. A high-quality scanning protocol, Harmonization Protocol (HARP), was established for five high-quality 3 T scanners to obtain multimodal brain images including T1 and T2-weighted, resting-state and task functional and diffusion-weighted MRI. Data are preprocessed and analyzed using approaches developed by the Human Connectome Project. Preliminary results in 30 TS demonstrated cortical thickness, myelin, functional connectivity measures are comparable across 5 scanners, suggesting sensitivity to subject-specific connectome. A total of 75 TS and more than two thousand patients with various psychiatric and neurological disorders are scheduled to participate in the project, allowing a mixed model statistical harmonization. The HARP protocols are publicly available online, and all the imaging, demographic and clinical information, harmonizing database will also be made available by 2024. To the best of our knowledge, this is the first project to implement a prospective, multi-level harmonization protocol with multi-site TS data. It explores intractable brain disorders across the lifespan and may help to identify the disease-specific pathophysiology and imaging biomarkers for clinical practice. |
| تدمد: | 2213-1582 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382f621c8d1cf70b268dac9e9cde00bfTest https://doi.org/10.1016/j.nicl.2021.102600Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....382f621c8d1cf70b268dac9e9cde00bf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22131582 |
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