المؤلفون: Logan J. Voss, Martyn G. Harvey, James W. Sleigh

المصدر: Frontiers in Pain Research, Vol 3 (2022)

مصطلحات موضوعية: ketamine, analgesia, NMDA – N-methyl-D-aspartate, potassium channels, psychomimetic, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fpain.2022.827372/fullTest; https://doaj.org/toc/2673-561XTest

الوصول الحر: https://doaj.org/article/ecf55d4a9a8c45af8e7bc008ee12d80eTest

المؤلفون: Amir Meftah, Hiroshi Hasegawa, Joshua T. Kantrowitz

المصدر: Frontiers in Psychiatry, Vol 12 (2021)

مصطلحات موضوعية: NMDA–N-methyl-D-aspartate, D-serine, schizophrenia, safety, kidney, Psychiatry, RC435-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fpsyt.2021.726365/fullTest; https://doaj.org/toc/1664-0640Test

الوصول الحر: https://doaj.org/article/dd733f952eb44a788d48a10562b16004Test

المؤلفون: Matos, Claudia Marques, Lim, Ming, Madureira, Ines, Duarte, Sofia, Byrne, Susan, Rossor, Thomas, Dahiya, Devika

المصدر: Brain, behavior, & immunity - health ; 28 ; 100602 ; United States

مصطلحات موضوعية: Auto-immune encephalitis, CSF – Cerebral Spinal Fluid, IVIG – Intravenous Immunoglobulin, Cross reactivity, Molecular mimicry, NG – Nasogastric, NMDA - N-methyl-D-aspartate, Neuropsychiatric syndrome, PANDAS - Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus), PANS - Pediatric Acute onset Neuropsychiatric Syndrome, PET- FDG - positron emission tomography - fluorodeoxyglucose, VZV - Varicella Zoster Virus, Pediatric varicella zoster virus, ADHD - Attention Deficit Hyperactivity Disorder, CNS – Central Nervous System

العلاقة: http://hdl.handle.net/10147/635137Test; Brain, behavior, & immunity - health; PMC9969201

الإتاحة: https://doi.org/10.1016/j.bbih.2023.100602Test
http://hdl.handle.net/10147/635137Test

المؤلفون: Lauren Ratcliffe, Sabrina McAllister, Jacob Johnson, Paige Dzindolet

المصدر: Impulse: The Premier Undergraduate Neuroscience Journal (2018)

مصطلحات موضوعية: working memory, blurred vision, and spatial awareness. Neuropsychological tests, such as the trail making test (TMT), have been shown to assess the severity of impairment. Prior research in this area has exclusively assessed these impairments via driving performance. This study aimed to investigate neurocognitive impairments associated with varying BAC levels utilizing a computerized trail making test (cTMT), which reduces practice effects via randomized stimuli location. The influences of alcohol were tested over the variables of total time, median latency, and version (Trail A, Trail B). Twenty-six participants (8 male, 18 female) with a minimum age of 21 years were recruited. Participants were randomly selected to be in the placebo (n=7) or the experimental group (n=19). The experimental group performed the cTMT at four target BAC points: baseline (0.00 mg/ml), ascending (0.06 mg/ml), peak (0.08 mg/ml), and descending (0.06 mg/ml). While participants who received alcohol tended to report themselves at a lower BAC than they were, there was no significant difference between perceived and actual BAC. Additionally, alcohol did not significantly affect performance on the cTMT for the tested levels. The cTMT detected impairments during the complex task (Trail B) but not in the simpler task (Trail A), thus indicating cognitive inflexibility and deficits in working memory. Future studies could attempt to augment BAC levels to at least 0.10 mg/ml in order to examine more distinct effects of alcohol on the specific cognitive tasks required by the cTMT. Abbreviations: BAC – Blood Alcohol Concentration, CNS – Central Nervous System, cTMT – computerized Trail Making Test, GABA – Gamma-Aminobutyric Acid, NMDA - N-Methyl-D- Aspartate, PI – Principle Investigator, TMT – Trail Making Test Keywords: Executive Functioning, Trail Making Test, Visuomotor, Young Adult, Executive Functioning, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://impulse.appstate.edu/articles/2018/during-ascending-and-descending-limbs-blood-alcohol-concentration-curveTest; https://doaj.org/toc/1934-3361Test

الوصول الحر: https://doaj.org/article/afb609f953f24349b13dcd337a56c488Test

المؤلفون: Rondanelli M, Faliva MA, Miccono A, Naso M, NICHETTI, MARA, RIVA, ANTONELLA, Guerriero F, De Gregori M, Peroni G, Perna S

المساهمون: Rondanelli, M, Faliva, Ma, Miccono, A, Naso, M, Nichetti, Mara, Riva, Antonella, Guerriero, F, De Gregori, M, Peroni, G, Perna, S

مصطلحات موضوعية: ALA α-linolenic acid, COX cyclo-oxygenase, CRP C-reactive protein, EVO extra virgin olive oil, LAO long-acting specific opioid formulation, MCP-1 monocyte chemotactic protein-1, NMDA N-methyl-d-aspartate, NSAID non-steroidal anti-inflammatory drug, OA osteoarthrosi, OIC opioid-induced constipation, SIRT1 sirtuin-1, TLR Toll-like receptor, TRP transient receptor potential, Antioxidant, Chronic pain, Constipation, Food pyramid, Inflammation, Nutrient, Opioids

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29679994; volume:31; issue:1; firstpage:131; lastpage:151; numberofpages:21; journal:NUTRITION RESEARCH REVIEWS; http://hdl.handle.net/11571/1246686Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85045737736

الإتاحة: https://doi.org/10.1017/S0954422417000270Test
http://hdl.handle.net/11571/1246686Test

المؤلفون: F Al-Zoghaibi, Asma S.A. Alonazi, Asim Azhar, Khaled A. Al-Hosaini

المصدر: Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 6, Pp 539-551 (2021)

مصطلحات موضوعية: 0301 basic medicine, ERK, Extracellular signal-Regulated Kinase, cAMP, cyclic AMP, G protein, CCR, Chemokine Receptor, GLP1R, Glucagon-Like Peptide-1 Receptor, Druggability, Heterodimerization, Pharmaceutical Science, RM1-950, Review, Computational biology, COX, Cyclooxygenase, Biology, GRKs, AC, Adenylyl Cyclase, 03 medical and health sciences, GPCR, 0302 clinical medicine, DAG, Diacylglycerol, Arrestin, PKA, Protein Kinase A, PIP2, Phosphatidylinositol-4,5-bisphosphate, Receptor, Gene, GRKs, G protein-coupled Receptor Kinases, G protein-coupled receptor, Pharmacology, G protein-coupled receptor kinase, NMDA, N-Methyl D-Aspartate, Drugs, Nbs, Nanobodies, MAPK, Mitogen-Activated Protein Kinase, Signaling, 030104 developmental biology, PAR-1, Protease Activated Receptor 1, Therapeutics. Pharmacology, IP3, Inositol 1,4,5-triphosphate, GIP, Gastric Inhibitory Peptide, 030217 neurology & neurosurgery, Function (biology), G proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14339e0def5699befb4d16ab07f7bd41Test
https://doi.org/10.1016/j.jsps.2021.04.015Test

المساهمون: Biegon, A.

المصدر: JOURNAL OF MOLECULAR NEUROSCIENCE; 51; suppl. 1; Conference: 21st Annual Meeting of the Israel Society for Neuroscience ...; Eilat (Israel); 20121215 through 20121218

وصف الملف: Medium: X; Size: S113 - S1136

الوصول الحر: http://www.osti.gov/scitech/biblio/1132997Test

المؤلفون: Dominik Strzelecki, Olga Kałużyńska, Justyna Szyburska, Adam Wysokiński

المصدر: International Journal of Molecular Sciences; Volume 17; Issue 7; Pages: 1075

مصطلحات موضوعية: matrix metallopeptidase-9 (MMP-9), sarcosine, NMDA ( N -methyl- d -aspartate) receptor, glutamatergic system, schizophrenia, negative symptoms

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms17071075Test

الإتاحة: https://doi.org/10.3390/ijms17071075Test

المؤلفون: Katsushige Sato, Yoko Momose-Sato

المصدر: IBRO Reports
IBRO Reports, Vol 9, Iss, Pp 14-23 (2020)

مصطلحات موضوعية: 0301 basic medicine, Nicotine, Central nervous system, E, embryonic day (days of incubation in avians and days of pregnancy in mammals), Article, lcsh:RC321-571, 03 medical and health sciences, chemistry.chemical_compound, NTS, nucleus of the tractus solitarius, In ovo, 0302 clinical medicine, medicine, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Acetylcholine receptor, NMDA, N-methyl-D-aspartate, Chemistry, General Neuroscience, Depolarization, Strychnine, Bicuculline, nAChR, nicotinic acetylcholine receptor, Optical recording, Voltage-sensitive dye, CNQX, 6-cyano-7-nitroquinoxaline-2,3-dione, PBN, parabrachial nucleus, Vagus nerve, Cell biology, Spontaneous activity, Synaptic network formation, 030104 developmental biology, medicine.anatomical_structure, Nicotinic agonist, APV, DL-2-amino-5-phosphonovaleric acid, EPSP, excitatory postsynaptic potential, GABA, γ-aminobutyric acid, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09eaf4e16fe459a8b5894cdd3651612dTest
http://europepmc.org/articles/PMC7334560Test

المؤلفون: Xu Shen, Xiaoxia Qiu, Jiaying Wang, Wenwen Liu, Xiaokang Li, Fei Mao, Jian Lu, Baoli Li, Jin Zhu, Yixiang Xu, Jian Li, Lei Fan

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 4, Pp 646-666 (2020)

مصطلحات موضوعية: Original article, Nitazoxanide, Aβ, β-amyloid, Tau protein, mTOR, mammalian target of rapamycin, Pharmacology, CNS, central nervous system, PBL, porcine brain lipid, NFTs, neurofibrillary tangles, 03 medical and health sciences, 0302 clinical medicine, WORT, wortmannin, APP, amyloid precursor protein, Autophagy, medicine, NTZ, nitazoxanide, General Pharmacology, Toxicology and Pharmaceutics, BBB, blood–brain barrier, PI3K/AKT/mTOR pathway, 030304 developmental biology, 0303 health sciences, biology, β-amyloid, Activator (genetics), Drug discovery, business.industry, lcsh:RM1-950, NMDA, N-methyl-d-aspartate, Alzheimer's disease, PAMPA, parallel artificial membrane permeation assay, MWM, Morris Water Maze, Drug repositioning, lcsh:Therapeutics. Pharmacology, AChEIs, acetylcholinesterase inhibitors, SPs, senile plaques, 030220 oncology & carcinogenesis, biology.protein, Phosphorylation, AD, Alzheimer's disease, NCEs, new chemical entities, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe46f557fb401b09743b51fe8f97388Test
https://doi.org/10.1016/j.apsb.2019.07.006Test