المؤلفون: Jing Wang, Pan Tong, Monique B. Nilsson, Tina Cascone, Erik P. Sulman, Alissa Poteete, Piyada Sitthideatphaiboon, Faye M. Johnson, Shaohua Peng, Li Shen, John V. Heymach, Naoto Morikawa, Qiuyu Wu, Jean-Christophe Bourdon, Phillip Jones, Fahao Zhang, Jayanthi Gudikote, Lerong Li

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: p53, Nonsense-mediated decay, DMSO, dimethyl sulfoxide, Biochemistry, Exon, alternative splicing, Mice, mRNA decay, RNA degradation, MDM2, NSCLC, non–small cell lung cancer, medicine, Animals, Humans, Protein Isoforms, Molecular Biology, biology, Chemistry, NMD, nonsense-mediated decay, Alternative splicing, Wild type, Cancer, PTC, premature termination codon, Proto-Oncogene Proteins c-mdm2, Cell Biology, GBM, glioblastoma multiforme, medicine.disease, Nonsense Mediated mRNA Decay, Gene Expression Regulation, Neoplastic, Apoptosis, A549 Cells, Cancer cell, Mutation, biology.protein, Cancer research, Mdm2, cancer therapy, IR, ionizing radiation, targeting NMD, p53β/γ restoration, Tumor Suppressor Protein p53, NMDi, NMD inhibitor, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141972075328430857ff8891a8eb428eTest
http://europepmc.org/articles/PMC8569473Test

المؤلفون: Gotkine, M, de Majo, M, Wong, CH, Topp, SD, Michaelson-Cohen, R, Epsztejn-Litman, S, Eiges, R, Y, YL, Kanaan, M, Shaked, HM, Alahmady, N, Vance, C, Newhouse, SJ, Breen, G, Nishimura, AL, Shaw, CE, Smith, BN

مصطلحات موضوعية: ALS (Amyotrophic Lateral Sclerosis), Allele, LoF (loss of function), NMD (nonsense mediated decay), Optineurin, Aged, 80 and over, Alleles, Amyotrophic Lateral Sclerosis, Cell Cycle Proteins, Consanguinity, Female, Gene Expression, Genes, Recessive, Genetic Association Studies, Heterozygote, Humans, Loss of Function Mutation, Male, Membrane Transport Proteins, Middle Aged, Middle East, Nonsense Mediated mRNA Decay, RNA, Messenger, Risk Factors

وصف الملف: 351.e1 - 351.e6

العلاقة: Neurobiol Aging; https://qmro.qmul.ac.uk/xmlui/handle/123456789/93501Test

الإتاحة: https://doi.org/10.1016/j.neurobiolaging.2021.05.009Test
https://qmro.qmul.ac.uk/xmlui/handle/123456789/93501Test

المؤلفون: Saulle, Irma, Vicentini, Chiara, Clerici, Mario, Biasin, Mara

المصدر: Human Immunology

مصطلحات موضوعية: IRAP, insulin-regulated aminopeptidase, ERAP, endoplasmic reticulum aminopeptidase, ACE2, angiotensin-converting enzyme-2 receptor, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Aminopeptidases, ERAPs, WHO, World Health Organization, ER, endoplasmic reticulum, Minor Histocompatibility Antigens, Epitopes, HLA, between Human Leukocyte Antigen, HLA Antigens, MHC, major histocompatibility complex, Animals, Humans, TAP, transporter associated with antigen processing, GWAS, genome-wide association study, Antigens, Viral, ARDS, acute respiratory distress syndrome, COVID-19, coronavirus disease 2019, Antigen Presentation, Polymorphism, Genetic, SARS-CoV-2, COVID-19, MERS-CoV, Middle East respiratory syndrome coronavirus, SNP, single nucleotide polymorphism, NMD, nonsense-mediated-decay, HLA, CTL, Cytotoxic T Lymphocytes, Host-Pathogen Interactions, Polymorphisms, RDB, receptor-binding domain, ERGIC, ER Golgi Intermediate Compartment, TMPRSS2, type II transmembrane serine protease, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::51bc5413b4c2d797c3cdef74cf69940dTest
https://pubmed.ncbi.nlm.nih.gov/34116863Test

المؤلفون: Woodward, Lauren A.

مصطلحات موضوعية: Molecular Biology, EJC, PYM, translation, NMD, nonsense-mediated decay, Exon Junction Complex

الإتاحة: http://rave.ohiolink.edu/etdc/view?acc_num=osu1574724716785331Test

المؤلفون: Junxiu Sheng, Yuesheng Lv, Yangfan Qi, Lin Zhang, Xiaoling Li, Chundong Gu, Ge Zhang, Hong Gu, Qingzhi Zhao, Lei Chen, Bing Sun, Lu Bai, Judy M. Coulson, Quan Yang, Jinyao Zhao, Wenjing Zhang, Xiaoqin Deng, Yang Wang, Pan Qin, Yu Sun, Songshu Meng, Quentin Liu, Han Liu

المصدر: EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, AMPK, Lung Neoplasms, Research paper, AMPK, AMP-activated Protein Kinase, PTPMT1, EMT, epithelial to mesenchymal transition, Biology, AMP-Activated Protein Kinases, medicine.disease_cause, Radiation Tolerance, γH2AX, gamma-Histone H2AX, General Biochemistry, Genetics and Molecular Biology, Radio-resistance, 03 medical and health sciences, Splicing factor, Mice, Radioresistance, Cell Line, Tumor, medicine, Animals, Humans, DNA Breaks, Double-Stranded, AS, Alternative Splicing, Serine-Arginine Splicing Factors, NMD, nonsense-mediated decay, PTPMT1, Protein Tyrosine Phosphatase, Mitochondrial 1, Gene Expression Profiling, Chk2, Checkpoint kinase 2, Alternative splicing, PTEN Phosphohydrolase, Cancer, Computational Biology, General Medicine, medicine.disease, Xenograft Model Antitumor Assays, SR proteins, Serine/arginine-rich proteins, Gene Expression Regulation, Neoplastic, SRSF1, Serine/arginine-rich splicing factor 1, Alternative Splicing, Disease Models, Animal, 030104 developmental biology, RNA splicing, Cancer cell, Cancer research, IR, ionizing radiation, SRSF1, Serine/arginine-rich Splicing Factor 1, Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee6b7a92fee63aac22b7f4436470052Test
https://pubmed.ncbi.nlm.nih.gov/30429088Test

المؤلفون: Lance Wells, Jeremy L. Praissman

المصدر: Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Proteomics, (especially), Fe-NTA, (endosome), ER, Review, Disease, Biochemistry, N, (nucleocapsid protein), Analytical Chemistry, MOI, (multiplicity of infection), (endoplasmic reticulum), ERGIC, Pandemic, CPTAC, (Clinical Proteomic Tumor Analysis Consortium), Global health, NM, (nuclear membrane), ORF, (open reading frame), European Bioinformatics Institute), EN, (Global Initiative on Sharing Avian Influenza Data), gRNA, M, (membrane protein), Repurposing, PBMC, (peripheral blood mononuclear cell), 0303 health sciences, SILAC, (Stable Isotope Labeling by Amino acids in Cell culture), PLpro, (papain-like protease), PM, (plasma membrane), 030302 biochemistry & molecular biology, DDA, (data-dependent acquisition), SARS-CoV-1, (Severe Acute Respiratory Syndrome Coronavirus 1), ACE2, (angiotensin-converting enzyme 2), (ferric nitrilotriacetate), FP, RBD, (receptor binding domain), (genomic RNA), HCD, (endoplasmic reticulum golgi intermediate compartment), ERM, NMD, (nonsense mediated decay), MAVS, (mitochondrial antiviral signaling), Mpro, (main protease), LY, (lysosome), RPLC, (reversed phase liquid chromatography), Host-Pathogen Interactions, Proteome, mePROD, (multiplexed enhanced protein dynamics), RNP, (ribonucleoprotein), Angiotensin-Converting Enzyme 2, PPI, (protein-protein interaction), (heptad repeat 1), HR2, ADP, (adenosine diphosphate), COVID-19, (Coronavirus Disease 2019), oxid, (oxidation), CP, (cytoplasm), S, (spike or surface glycoprotein), PRM, (parallel reaction monitoring), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), (endoplasmic reticulum membrane), esp, NO, (nucleolus), Computational biology, MT, (mitochondria), ss-RNA, (single-stranded RNA), Biology, Viral Proteins, 03 medical and health sciences, (heparan sulfate), LC-MS, Humans, BioGRID, (Biological General Repository for Interaction Datasets), nsp, (nonstructural protein), Molecular Biology, PN, (perinuclear), TMT, (tandem mass tag), 030304 developmental biology, (higher-energy collisional dissociation), HR1, (liquid chromatography, mass spectrometry), sgRNA, (subgenomic RNA), SARS-CoV-2, 3CLpro, (3C-like protease), DIA, (data-independent acquisition), COVID-19, NCBI, (National Center for Biotechnology Information), deamid, (deamidation), Virus Internalization, Glycome, SARS, (Severe Acute Respiratory Syndrome), EMBL-EBI, (European Molecular Biology Laboratory, (fusion peptide), GISAID, qPCR, (quantitative polymerase chain reaction), E, (envelope protein), PCR, (polymerase chain reaction), LLOD, (lower limit of detection), NU, (nucleus), PTM, (post-translational modification), SARS-CoV-2, (Severe Acute Respiratory Syndrome Coronavirus 2), Protein Processing, Post-Translational, (heptad repeat 2), HS, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9675b2a65579d400f59eadddc4bb6803Test
https://doi.org/10.1016/j.mcpro.2021.100103Test

المؤلفون: Gay Carter, Branko Miladinovic, Achintya A. Patel, Lauren Deland, Stephen Mastorides, Niketa A. Patel

المصدر: BBA Clinical

مصطلحات موضوعية: Serum, medicine.medical_specialty, NMD, nonsense mediated decay, BMI, body mass index, AUC, area under curve, Bioinformatics, Pathology and Forensic Medicine, lncRNA, DM, diabetes mellitus, GAS5, growth-arrest specific transcript 5, Physiology (medical), Internal medicine, Diabetes mellitus, GAS5, Gene expression, medicine, Adult Onset Diabetes, Metabolic disease, Veterans, business.industry, Diabetes, Type 2 Diabetes Mellitus, Regular Article, ROC, receiver operating characteristics, medicine.disease, Impaired fasting glucose, Long non-coding RNA, CI, confidence interval, Endocrinology, Molecular Medicine, lncRNA, long noncoding RNA, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360329258ea8284cf21adbd55d9bf3a0Test
https://doi.org/10.1016/j.bbacli.2015.09.001Test

المؤلفون: Mockenhaupt, Stefan, Makeyev, Eugene V.

المساهمون: School of Biological Sciences

المصدر: Seminars in Cell & Developmental Biology

مصطلحات موضوعية: nt, nucleotide, NMTR, nonsense-mediated translational repression, Alternative pre-mRNA splicing, NRE, nuclear retention and elimination, uORF, upstream open reading frame, RNA Stability, Development, RUST, regulated unproductive splicing and translation, Article, Evolution, Molecular, Morphogenesis, RNA Precursors, Animals, Humans, mRNA stability, APA, alternative cleavage and polyadenylation, ARE, AU-rich element, Models, Genetic, NMD, nonsense-mediated decay, A3E, alternative 3′ terminal exon, Gene Expression Regulation, Developmental, PTC, premature termination codon, Cell Biology, Translational regulation, Alternative Splicing, IR, intron retention, Protein Biosynthesis, mRNA localization, AS, alternative splicing, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::886bcc377f640cab0a9bb1d9f80982bcTest

المؤلفون: Thomas, Gonatopoulos-Pournatzis, Victoria H, Cowling

المصدر: Biochemical Journal

مصطلحات موضوعية: RNA Caps, Ars2, arsenite-resistance protein 2, TMG, 2,2,7-trimethylguanosine cap, ABA, abscisic acid, Cbp, cap-binding protein, translation, Cdk9, cyclin-dependent kinase 9, Review Article, TREX, transcription export complex, eIF, eukaryotic initiation factor, splicing, SRSF1, serine/arginine-rich splicing factor 1, parasitic diseases, Animals, Humans, CBC, cap-binding complex, PARN, poly(A)-specific ribonuclease, RNA, Messenger, NELF, negative elongation factor, RAM, RNMT-activating mini-protein, Nuclear Cap-Binding Protein Complex, Guanosine, cap-binding complex (CBC), NMD, nonsense-mediated decay, MIF4G, middle domain of eIF4G, snRNP, small nuclear ribonucleoprotein, 7-methylguanosine cap (7mG), mTORC1, mammalian target of rapamycin complex 1, PHAX, phosphorylated adaptor of RNA export, PTC, premature termination codon, 7mG, 7-methylguanosine cap, RRM, RNA-recognition motif, CTD, C-terminal domain, RNA pol II, RNA polymerase II, Gene Expression Regulation, CF IA, cleavage factor IA, RNA Cap-Binding Proteins, hnRNP, heterogeneous nuclear ribonucleoprotein, PABP, poly(A)-binding protein, mRNP, messenger ribonucleoprotein, transcription, CTIF, CBC-dependent translation initiation factor, DSIF, DRB sensitivity-inducing factor, Signal Transduction, P-TEFb, positive transcription elongation factor b, RNMT, RNA (guanine-7-)methyltransferase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::85f784ec3298f3bf10931336bc5f877eTest
https://pubmed.ncbi.nlm.nih.gov/24354960Test

المؤلفون: Joanna Somers, Tuija Pöyry, Anne E. Willis

المصدر: The International Journal of Biochemistry & Cell Biology

مصطلحات موضوعية: Untranslated region, uORF, upstream open reading frame, Five prime untranslated region, NMD, nonsense mediated decay, Eif, eukaryotic initiation factor, Biology, Biochemistry, Upstream open reading frame, Article, Open Reading Frames, THPO, thrombopoietin, Protein biosynthesis, Animals, Humans, Disease, IRES, internal ribosome entry segment, Codon, Peptide Chain Initiation, Translational, Genetics, Mammals, Messenger RNA, Models, Genetic, RNA, EMCV, encephalomyocarditis virus, Translational control, Cell Biology, SNP, single nucleotide polymorphism, AdoMetDCS, adenosyl-methionine decarboxylase, 4EBPs, 4E-binding proteins, RRL, rabbit reticulocyte lysate, Internal ribosome entry site, Open reading frame, UTR, untranslated region, Protein synthesis, uORF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b00ca162cfd53a3e5a2dad69f3ea60Test
https://pubmed.ncbi.nlm.nih.gov/23624144Test