دورية أكاديمية
Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective
العنوان: | Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective |
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المؤلفون: | Sims, Emily K., Besser, Rachel E. J., Dayan, Colin, Rasmussen, Cristy Geno, Greenbaum, Carla, Griffin, Kurt J., Hagopian, William, Knip, Mikael, Long, Anna E., Martin, Frank, Mathieu, Chantal, Rewers, Marian, Steck, Andrea K., Wentworth, John M., Rich, Stephen S., Kordonouri, Olga, Ziegler, Anette-Gabriele, Herold, Kevan C., NIDDK Type 1 Diabetes TrialNet Study Group |
المساهمون: | Pediatrics, School of Medicine |
المصدر: | PMC |
بيانات النشر: | American Diabetes Association |
سنة النشر: | 2022 |
المجموعة: | Indiana University - Purdue University Indianapolis: IUPUI Scholar Works |
مصطلحات موضوعية: | Autoantibodies, Type 1 diabetes mellitus, Mass screening |
الوصف: | Most screening programs to identify individuals at risk for type 1 diabetes have targeted relatives of people living with the disease to improve yield and feasibility. However, ∼90% of those who develop type 1 diabetes do not have a family history. Recent successes in disease-modifying therapies to impact the course of early-stage disease have ignited the consideration of the need for and feasibility of population screening to identify those at increased risk. Existing population screening programs rely on genetic or autoantibody screening, and these have yielded significant information about disease progression and approaches for timing for screening in clinical practice. At the March 2021 Type 1 Diabetes TrialNet Steering Committee meeting, a session was held in which ongoing efforts for screening in the general population were discussed. This report reviews the background of these efforts and the details of those programs. Additionally, we present hurdles that need to be addressed for successful implementation of population screening and provide initial recommendations for individuals with positive screens so that standardized guidelines for monitoring and follow-up can be established. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
العلاقة: | Diabetes; Sims EK, Besser REJ, Dayan C, et al. Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective. Diabetes. 2022;71(4):610-623. doi:10.2337/dbi20-0054; https://hdl.handle.net/1805/36689Test |
الإتاحة: | https://doi.org/10.2337/dbi20-0054Test https://hdl.handle.net/1805/36689Test |
حقوق: | Publisher Policy |
رقم الانضمام: | edsbas.DD537D18 |
قاعدة البيانات: | BASE |
الوصف غير متاح. |