المؤلفون: Michele Fiore, Michele Mosconi, Francesco Bonì, Alice Parodi, Annalisa Salis, Bruno Tasso, Eloise Mastrangelo, Enrico Millo, Federica Cossu

المصدر: Molecules; Volume 28; Issue 1; Pages: 446

مصطلحات موضوعية: baculoviral IAP repeat (BIR), inhibitor of apoptosis protein (IAP), NF-κB (nuclear factor kappa light chain enhancer of activated B cells), benzodiazepinone, virtual docking, MDA-MB-231

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28010446Test

الإتاحة: https://doi.org/10.3390/molecules28010446Test

المؤلفون: Clovis H. T. Seumen, Tanja M. Grimm, Christof R. Hauck

المصدر: Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-18 (2021)

مصطلحات موضوعية: Protein serine/threonine phosphatase, Toll-like receptors, Innate immunity, Phosphorylation, Inflammation, NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells), Medicine, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1478-811XTest

الوصول الحر: https://doaj.org/article/66daff73de5342688e07a006799feb39Test

المؤلفون: Christophe Glorieux, Peng Huang

المصدر: Cancer Communications, Vol 39, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: CD137, K-Ras, IL-1α (interleukin-1 alpha), MAPK (mitogen-activated protein kinases), NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells), Pancreatic cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s40880-019-0386-4Test; https://doaj.org/toc/2523-3548Test

الوصول الحر: https://doaj.org/article/0557979dbd21466ab387605fa3f7d6a5Test

المؤلفون: Seumen, Clovis H. T., Grimm, Tanja M., Hauck, Christof R.

المصدر: Cell Communication and Signaling. BioMed Central. 2021, 19(1), 45. eISSN 1478-811X. Available under: doi:10.1186/s12964-021-00722-1

مصطلحات موضوعية: Protein serine/threonine phosphatase, Toll-like receptors, Innate immunity, Phosphorylation, Inflammation, NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells), ddc:570

وصف الملف: application/pdf

العلاقة: http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1vq7r9frvujnk0Test; http://dx.doi.org/10.1186/s12964-021-00722-1Test

الإتاحة: https://doi.org/10.1186/s12964-021-00722-1Test
http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1vq7r9frvujnk0Test

المؤلفون: Fiore, Michele, Mosconi, Michele, Bonì, Francesco, Parodi, Alice, Salis, Annalisa, Tasso, Bruno, Mastrangelo, Eloise, Millo, Enrico, Cossu, Federica

المساهمون: Fiore, Michele, Mosconi, Michele, Bonì, Francesco, Parodi, Alice, Salis, Annalisa, Tasso, Bruno, Mastrangelo, Eloise, Millo, Enrico, Cossu, Federica

مصطلحات موضوعية: MDA-MB-231, NF-κB (nuclear factor kappa light chain enhancer of activated B cells), baculoviral IAP repeat (BIR), benzodiazepinone, inhibitor of apoptosis protein (IAP), virtual docking

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36615638; info:eu-repo/semantics/altIdentifier/wos/WOS:000911132700001; volume:28; firstpage:446; lastpage:461; numberofpages:16; journal:MOLECULES; https://hdl.handle.net/11567/1105567Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85145678912

الإتاحة: https://doi.org/10.3390/molecules28010446Test
https://hdl.handle.net/11567/1105567Test

المؤلفون: Suchetana Gupta, Ditipriya Mallick, Kumarjeet Banerjee, Shrimon Mukherjee, Soumyadev Sarkar, Sonny TM Lee, Partha Basuchowdhuri, Siddhartha S Jana

المصدر: Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 766-778 (2022)
Computational and Structural Biotechnology Journal

مصطلحات موضوعية: Cryo-EM, Cryo Electron Microscope, In silico, ORF3a, RMSD, Root Mean Square Deviation, Mutant, Biophysics, Virulence, Biochemistry, Interactome, Article, MMGBSA, Molecular mechanics with generalized Born and surface area solvation, BLAST, Basic Local Alignment Search Tool, NF-κB, Nuclear factor kappa light chain enhancer of activated B cells, ORF, Open Reading Frame, PROVEAN, Protein Variation Effect Analyzer, Caveolin-1, Structural Biology, PDB, Protein Data Bank, Molecular dynamics simulation, Genetics, ASC, Apoptosis associated speck-like protein containing a caspase recruitment domain, CD4+, Cluster of Differentiation 4+, ComputingMethodologies_COMPUTERGRAPHICS, HMOX1, Heme Oxygenase 1, TRIM59, Tripartite motif-containing protein 59, chemistry.chemical_classification, SUN2, SUN domain-containing protein 2, Chemistry, SARS-CoV-2, PISA, Protein Interfaces Surfaces and Assemblies, ARL6IP6, ADP Ribosylation Factor Like GTPase 6 interacting protein 6, MERS-CoV, Middle East respiratory syndrome coronavirus, NLRP3, Nucleotide-binding oligomerization domain, Leucine rich repeat and Pyrin domain containing, NCBI, National Centre for Biotechnology Information, Computer Science Applications, IFN, Interferon, Amino acid, Graph theory, Docking (molecular), COVID-19, Coronavirus Disease 2019, Caveolin 1, Mutation, CD8+, Cluster of Differentiation 8+, Salt bridge, TP248.13-248.65, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77e75e84ff2110441d6e92dcaabf7e8Test
http://www.sciencedirect.com/science/article/pii/S2001037022000241Test

المؤلفون: Hai-Yong Chen, Yibin Feng, Cheng Zhang, Ning Wang, Sha Li, Guoyi Tang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)

مصطلحات موضوعية: LOX1, lectin-like oxidized LDL receptor 1, BUN, blood urea nitrogen, TGBM, thickness of glomerular basement membrane, NQO1, NAD(P)H:quinone oxidoreductase 1, STAT, signal transducers and activators of transcription, N/O, not observed, p62, sequestosome 1 protein, p-IRS1, phospho-IRS1, Review, NOX-4, nicotinamide adenine dinucleotide phosphate-oxidase-4, OCP, oxidative carbonyl protein, Traditional Chinese medicine, AGEs, advanced glycation end-products, N/A, not applicable, TRAF5, tumor-necrosis factor receptor-associated factor 5, Health problems, 0302 clinical medicine, ESRD, end-stage renal disease, LDL, low-density lipoprotein, BMP-7, bone morphogenetic protein-7, TGFβR-I/II, TGF-β receptor I/II, Medicine, P70S6K, 70-kDa ribosomal protein S6 kinase, General Pharmacology, Toxicology and Pharmaceutics, SOCS, suppressor of cytokine signaling proteins, HO-1, heme oxygenase-1, 0303 health sciences, TG, triglyceride, BW, body weight, HDL-C, high density lipoprotein-cholesterol, RASI, renin-angiotensin system inhibitor, ATK, protein kinase B, TBARS, thiobarbituric acid-reactive substance, BCL-XL, B-cell lymphoma-extra large, Gαq, Gq protein alpha subunit, GCK, glucokinase, PI3K, phosphatidylinositol 3 kinases, Systematic review, TLR-2/4, toll-like receptor 2/4, IR, insulin receptor, PERK, protein kinase RNA-like eukaryotic initiation factor 2A kinase, 030220 oncology & carcinogenesis, CRP, C-reactive protein, IRS, insulin receptor substrate, AM, mesangial area, JAK, Janus kinase, FBG, fasting blood glucose, ETAR, endothelium A receptor, LDL-C, low density lipoprotein-cholesterol, CD2AP, CD2-associated protein, eIF2α, eukaryotic initiation factor 2α, RM1-950, mTOR, mammalian target of rapamycin, CHOP, C/EBP homologous protein, STZ, streptozotocin, 03 medical and health sciences, ADE, adverse event, PKC, protein kinase C, LC3, microtubule-associated protein light chain 3, ORP150, 150-kDa oxygen-regulated protein, PGE2, prostaglandin E2, IL-1β/6, interleukin 1β/6, Diabetic kidney disease, IGF-1, insulin-like growth factor 1, EP, E-prostanoid receptor, FN, fibronectin, eGFR, estimated GFR, MDA, malondialdehyde, Chinese medicine, MMP-2, matrix metallopeptidase 2, XBP-1, spliced X box-binding protein 1, TGF-β, tumor growth factor β, GRB 10, growth factor receptor-bound protein 10, medicine.disease, Clinical trial, GRP78, glucose-regulated protein 78, UP, urinary protein, IGF-1R, insulin-like growth factor 1 receptor, ACEI, angiotensin-converting enzyme inhibitor, BCL-2, B-cell lymphoma 2, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase, MYD88, myeloid differentiation primary response 88, PBG, postprandial blood glucose, RCT, randomized clinical trial, N/R, not reported, COL-I/IV, collagen I/IV, PINK1, PTEN-induced putative kinase 1, UACR, urinary albumin to creatinine ratio, C, control group, Diabetic nephropathy, GPX, glutathione peroxidase, ICAM-1, intercellular adhesion molecule-1, Bioinformatics, VCAM-1, vascular cell adhesion molecule-1, AMPKα, adenosine monophosphate-activated protein kinase α, DM, diabetes mellitus, TFEB, transcription factor EB, TNF-α, tumor necrosis factor α, Molecular target, IKK-β, IκB kinase β, Signaling pathway, GLUT4, glucose transporter type 4, BAX, BCL-2-associated X protein, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, PARP, poly(ADP-Ribose) polymerase, SMURF-2, SMAD ubiquitination regulatory factor 2, AREs, antioxidant response elements, MD, mean difference, SMAD, small mothers against decapentaplegic, MCP-1, monocyte chemotactic protein-1, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, ARB, angiotensin receptor blocker, PAI-1, plasminogen activator inhibitor-1, SMD, standard mean difference, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IκB-α, inhibitory protein α, Herbal medicine, TCM, traditional Chinese medicine, DG, glomerular diameter, GSK-3, glycogen synthase kinase 3, SIRT1, sirtuin 1, D, duration, HbA1c, glycosylated hemoglobin, WMD, weight mean difference, CTGF, connective tissue growth factor, ER, endoplasmic reticulum, DN, diabetic nephropathy, ROS, reactive oxygen species, CCR, creatinine clearance rate, SOD, superoxide dismutase, Diabetes mellitus, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1α, ET-1, endothelin-1, UMA, urinary microalbumin, SCr, serum creatinine, IRE-1α, inositol-requiring enzyme-1α, 030304 developmental biology, TII, tubulointerstitial injury index, RAGE, receptors of AGE, business.industry, GFR, glomerular filtration rate, PTEN, phosphatase and tensin homolog, CI, confidence interval, TC, total cholesterol, SD-rat, Sprague–Dawley rat, UAER, urinary albumin excretion rate, DKD, diabetic kidney disease, T, treatment group, Molecular targets, Therapeutics. Pharmacology, α-SMA, α smooth muscle actin, SD, standard deviation, business, DAG, diacylglycerol, GCLC, glutamate-cysteine ligase catalytic subunit, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d8ab4193adc39b242fa3c089b4f517Test
https://doi.org/10.1016/j.apsb.2020.12.020Test

المؤلفون: Siying Zhu, Matthew S. Tremblay, Sean B. Joseph, Seung Hyuk Choi, Mitch Hull, Weijun Shen, Valeria Marrocco, Sijia Li, Marta Diez Cunado, Ana M. Gamo, Tuan Tran, Jason Roland, Arnab K. Chatterjee, Qiangwei Fu, Van Nguyen-Tran, Nikki Rogers

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3983-3993 (2021)

مصطلحات موضوعية: TG, thapsigargin, Cell signaling, ATF4, activating transcription factor 4, IKKβ, inhibitor of nuclear factor kappa-B kinase subunit beta, PERK, PKR-like ER kinase, XBP1, X-box-binding protein 1, OGTT, oral glucose tolerance test, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Unfolded protein response, 0302 clinical medicine, UPR, unfolded protein response, GLuc, Gaussia luciferase, Chaperones, Protein biosynthesis, IL1β, interleukin 1β, General Pharmacology, Toxicology and Pharmaceutics, uHTS, ultra-high throughput screening, IRE1, inositol requiring enzyme 1α/β, 0303 health sciences, ASGR, asialoglycoprotein receptor 1, biology, Chemistry, Small molecules, Diabetes, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, ATF6, activating transcription factor 6α/β, β cells, i.p., intraperitoneal, Cell biology, Liver, 030220 oncology & carcinogenesis, T1/2D, type1/2 diabetes, Tm, tunicamycin, Protein folding, Original Article, ER stress, NASH, nonalcoholic steatohepatitis, INFγ, interferon gamma, TNFα, tumor necrosis factor alpha, RM1-950, GRPRP94, glucose-regulated protein 94, ER, endoplasmic reticulum, 03 medical and health sciences, SP1/2, serine protease1/2, GRP78, 78-kDa glucose-regulated protein, BID, twice a day, Pancreas, 030304 developmental biology, Reporter gene, Nod, non-obese diabetic, Activator (genetics), Endoplasmic reticulum, Metabolic diseases, Chaperone (protein), EGFP-VSVG, enhanced green fluorescence protein-vesicular stomatitis virus ts045 G protein, GSIS, glucose stimulated insulin secretion, biology.protein, Asialoglycoprotein receptor, Therapeutics. Pharmacology, CLuc, Cypridina luciferase, ERP72, endoplasmic reticulum proteins 72

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c176a631b2a5bf8251732009aad27d09Test
http://europepmc.org/articles/PMC8727761Test

المؤلفون: Kruttika Bhat, Le Zhang, Ling He, Neda A. Moatamed, Sara Duhacheck-Muggy, Angeliki Ioannidis, Nhan T. Nguyen, Frank Pajonk

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 197-209 (2021)

مصطلحات موضوعية: Proteomics, 0301 basic medicine, Cancer Research, c-Myc, myelocytoma, Organogenesis, medicine.medical_treatment, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Mammary gland, IL-12, interleukin 12, medicine.disease_cause, Receptors, Tumor Necrosis Factor, Mice, Breast cancer, 0302 clinical medicine, Oct4, octamer-binding transcription factor 4, Receptor, Mammary epithelial stem cells, Tumor necrosis factor alpha receptor, Klf4, Krüppel-like factor 4, Mice, Knockout, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, NF-kappa B, ELISA, enzyme-linked immunosorbent assay, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, TNFR, tumor necrosis factor receptor, 3. Good health, Cell Transformation, Neoplastic, medicine.anatomical_structure, Cytokine, 030220 oncology & carcinogenesis, NF-κB signaling, iNOS, inducible nitric oxide synthase, Cytokines, Female, Tumor necrosis factor alpha, Disease Susceptibility, Signal transduction, Signal Transduction, Original article, IKK, the inhibitor of nuclear factor-κB (IκB) kinase, TNFα, tumor necrosis factor alpha, Breast Neoplasms, lcsh:RC254-282, IL-1α, interleukin 1 alpha, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Receptors, Tumor Necrosis Factor, Type II, Autocrine signalling, Alleles, IFN-γ, interferon gamma, business.industry, medicine.disease, Disease Models, Animal, 030104 developmental biology, PMSF, phenylmethylsulfonyl fluoride, DTT, dithiothreitol, CXCL1, C-X-C Motif chemokine ligand 1, Cancer research, business, Carcinogenesis, Sox2, SRY (sex determining region Y)-box 2, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af59416ef11a1902b82c9c1a083c8797Test
https://doi.org/10.1016/j.neo.2020.12.007Test

المؤلفون: Azzam A. Maghazachi, Bariaa A. Khalil, Noha Mousaad Elemam

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 976-988 (2021)

مصطلحات موضوعية: ARDS, Chemokine, TLR, toll like receptor, Disease, Review, Biochemistry, CRS, cytokine releasing syndrome, GAGs, glycosaminoglycans, Pathogenesis, Chemokine receptor, 0302 clinical medicine, NK cells, natural killer cells, Structural Biology, Immunopathology, IP-10, IFN-γ-inducible protein 10, ARDS, acute respiratory disease syndrome, 0303 health sciences, biology, MERS-CoV, Middle East respiratory syndrome coronavirus, NF-κB, Nuclear Factor kappa-light-chain-enhancer of activated B cells, AECs, airway epithelial cells, Computer Science Applications, ECM, extracellular matrix, HIV, human immunodeficiency virus, CAP, community acquired pneumonia, 030220 oncology & carcinogenesis, Chemokine Receptors, DCs, dendritic cells, Chemokines, TRIF, TIR-domain-containing adapter-inducing interferon-β, Biotechnology, NETs, neutrophil extracellular traps, SARS-CoV, severe acute respiratory syndrome coronavirus, Biophysics, RSV, rous sarcoma virus, 03 medical and health sciences, BALF, bronchial alveolar lavage fluid, Immune system, Immunity, medicine, Genetics, IMM, inflammatory monocytes and macrophages, IFN, interferon, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, PBMCs, peripheral blood mononuclear cells, AP-1, Activator Protein 1, business.industry, SARS-CoV-2, COVID-19, medicine.disease, HRSV, human respiratory syncytial virus, PRR, pattern recognition receptors, Immunology, biology.protein, business, TP248.13-248.65, IRF, interferon regulatory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a813633e01cb0494554b46fedd72c61Test
http://europepmc.org/articles/PMC7859556Test