نتائج البحث - "NFκB, nuclear factor kappa B"

1

STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications

المؤلفون: David A. Frank, Isidora Tošić

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1167-1178 (2021)

مصطلحات موضوعية: Cancer Research, p53, tumor protein 53, MEF2D, Myocyte Enhancer Factor 2D, FASN, fatty acid synthase, OXPHOS, oxidative phosphorylation, ERH, enhancer of rudimentary homolog, PDGF, platelet-derived growth factor, PFK, phosphofructokinase, CREB, cyclic AMP response element-binding protein, HDL-C, high-density lipoprotein cholesterol, chemistry.chemical_compound, PC, phosphatidylcholine, GRIM-19, gene associated with retinoid-IFN-induced mortality, Neoplasms, Transcriptional regulation, TGFβ, transforming growth factor beta, AML, acute myeloid leukemia, RC254-282, CDK, cyclin-dependent kinase, FABP6, fatty acid binding protein 6, BCL, B-cell lymphoma, CLL, chronic lymphocytic leukemia, Chemistry, LIF, leukemia inhibitory factor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, VEGF, vascular endothelial growth factor, FBP1, fructose-bisphosphatase 1, GPI, glucose-6-phosphate isomerase, Cell biology, MMP, matrix metalloproteinase, STAT, signal transducer and activator of transcription, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, GP130, glycoprotein 130, Phosphorylation, NHL, non-Hodgkin's lymphoma, JAK, Janus kinase, Adenosine triphosphate, CNTF, ciliary neurotrophic factor, STAT3 Transcription Factor, ATP, adenosine triphosphate, TAG, triacylglycerol, Protein processing, Post-translational, PPARγ, peroxisome proliferator-activated receptor gamma, ETC, electron transport chain, TNFα, tumor necrosis factor alpha, RIME, rapid immunoprecipitation mass spectrometry of endogenous proteins, GLUT1, glucose transporter 1, PGK1, phosphoglycerate kinase, MPTP, mitochondrial permeability transition pore, Mediator, Review article, CML, chronic myeloid leukemia, HIF1α, hypoxia inducible factor 1α, PIAS, protein inhibitors of activated STATs, SOCS, suppressors of cytokine signaling, Animals, Humans, IFN, interferon, LDHA, lactate dehydrogenase A, Transcription factor, PKCδ, protein kinase C δ, TF, transcription factors, EGF, epidermal growth factor, SM, sphingomyelin, SREBP1, sterol regulatory element-binding protein 1, IAP, inhibitor of apoptosis, PTP, protein tyrosine phosphatases, Tyrosine phosphorylation, Lipid metabolism, BCSC, breast cancer stem cells, IL, interleukin, Metabolism, OSM, oncostatin M, Anaerobic glycolysis, NFκB, nuclear factor kappa B, TBK1, TANK-binding kinase 1, MCL, myeloid cell leukemia, LDL-C, low-density lipoprotein cholesterol, PBP, PPARγ binding protein, CPT1B, carnitine palmitoyltransferase 1B, FAO, fatty acid oxidation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fc1e221705a2edcb47149735290583Test
http://europepmc.org/articles/PMC8569436Test

2

Diet-induced hypothalamic dysfunction and metabolic disease, and the therapeutic potential of polyphenols

المؤلفون: Rabia Johnson, Ebrahim Samodien, Lawrence Mabasa, Johan Louw, Nireshni Chellan, Carmen Pheiffer, Melisse Erasmus

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 27, Iss, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Antioxidant, SOCS-3, suppressor of cytokine signaling-3, medicine.medical_treatment, Metabolic disease, Review, Pharmacology, medicine.disease_cause, 0302 clinical medicine, IR, insulin resistance, 2. Zero hunger, chemistry.chemical_classification, Neurodegeneration, food and beverages, IKκB, inhibitor of nuclear factor kappa-B kinase subunit beta, Neural mitochondrial dysfunction, 3. Good health, TLR4, Toll Like Receptor 4, medicine.symptom, lcsh:Internal medicine, Longevity, Hypothalamus, 030209 endocrinology & metabolism, Inflammation, POMC, pro-opiomelanocortin, NRF2, nuclear factor (erythroid-derived 2)-like 2 factor, STAT-3, signal transducer and activator of transcription 3, ARC, arcuate nucleus, 03 medical and health sciences, ROS, reactive oxygen species, Nutraceutical, Metabolic Diseases, medicine, Animals, Humans, Obesity, lcsh:RC31-1245, BBB, blood-brain-barrier, Molecular Biology, Nutrition, Reactive oxygen species, business.industry, Polyphenols, Cell Biology, PPs, polyphenols, medicine.disease, Diet, Hypothalamic inflammation, 030104 developmental biology, GTE, green tea extract, Mitochondrial biogenesis, chemistry, Dietary Supplements, NFκB, nuclear factor kappa B, SFAs, saturated fatty acids, business, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6d98bcfc10148c74cc22deffc56547Test
https://doi.org/10.1016/j.molmet.2019.06.022Test

3

The clinical translation of eicosanoids and other oxylipins, although challenging, should be actively pursued

المؤلفون: Cécile Gladine, Maria Fedorova

المساهمون: Unité de Nutrition Humaine (UNH), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Universität Leipzig, Universität Leipzig [Leipzig]

المصدر: Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2021, 21, pp.27-30. ⟨10.1016/j.jmsacl.2021.08.003⟩
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 27-30 (2021)

مصطلحات موضوعية: medicine.medical_specialty, TG - Triglyceride, Clinical Biochemistry, PPAR, peroxisome proliferator-activated receptor, CVD, cardiovascular disease, 030204 cardiovascular system & hematology, Microbiology, Special issue on Lipidomics, LDL, low density lipoprotein, PC, phosphatidylcholine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, PUFA, polyunsaturated fatty acid, Medical technology, Medicine, oxLDL, oxidized LDL, R855-855.5, Spectroscopy, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, 0303 health sciences, PUFA - Polyunsaturated fatty acid, CE, cholesteryl ester, TG, triglyceride, business.industry, Translation (biology), LDL - Low density lipoprotein, oxTG, oxidized TG, 3. Good health, Acute cardiovascular disease, Medical Laboratory Technology, PL, phospholipid, Endocrinology, NFκB, nuclear factor kappa B, oxCE, oxidized CE, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9276fa1e85369b86a9a3aec51ea7c48bTest
https://hal.inrae.fr/hal-03497751Test

4

Lipocalin 2 serum levels correlate with age and bone turnover biomarkers in healthy subjects but not in postmenopausal osteoporotic women

المؤلفون: Sjur Reppe, Anna Teti, Marco Ponzetti, Nadia Rucci, Antonio Maurizi, Kaare M. Gautvik

المصدر: Bone Reports
Bone Reports, Vol 14, Iss, Pp 101059-(2021)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, BMI, body mass index, Osteoporosis, BMD, bone mineral density, RANKL, receptor activator of nuclear factor kappa-B, Parathyroid hormone, Adipokine, 030209 endocrinology & metabolism, Diseases of the musculoskeletal system, Osteoarthritis, Article, NfκB, nuclear factor kappa-B, Bone remodeling, DKK1, Lipocalin-2, NGAL, Wnt, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, N-terminal telopeptide, Internal medicine, DKK1, Dickkopf WNT Signaling Pathway Inhibitor 1, NTX, N-terminal telopeptide of type I collagen, medicine, Orthopedics and Sports Medicine, PTH, parathyroid hormone, TRAcP5B, tartrate-resistant acid phosphatase 5B, TNF, tumor necrosis factor, business.industry, medicine.disease, IL, interleukin, BALP, bone-specific alkaline phosphatase, Endocrinology, RC925-935, chemistry, Cohort, Sclerostin, 030101 anatomy & morphology, business, CTX, C-terminal telopeptide of type I collagen, LCN2, lipocalin 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db17acf330e3e1697b12e7568c3b34fTest
http://europepmc.org/articles/PMC8121999Test

5

DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma

المؤلفون: Jinquan Cai, Ruijia Wang, Lin Lin, Hengyuan Pang, Magafurov Dinislam, Ziwei Li, Shihong Zhao, Qun Chen, Chuanlu Jiang, Pengfei Wu, Caijun Zha, Chunbin Duan, Xiangqi Meng, Bo Han

المصدر: EBioMedicine

مصطلحات موضوعية: Research paper, DNA Repair, Cellular differentiation, medicine.medical_treatment, ATRX, alpha thalassemia/mental retardation syndrome X-linked, SAA1, serum amyloid A1, Transcriptome, Mice, 0302 clinical medicine, GSEA, gene set enrichment analysis, GME, glioma microenvironment, MEM, Minimum Essential Media, BER, base excision repair, Midkine, TNFSF4, TNF superfamily member 4, NADP, nicotinamide adenine dinucleotide phosphate, General Medicine, DSBR, DNA double-strand break repair, 030220 oncology & carcinogenesis, NHEJ, nonhomologous end joining, Microglia, IHC, immunohistochemistry, γH2AX, phosphorylated on serine 139 on H2A histone family member X, CNV, copy number variation, IL6, interleukin 6, ATM, ataxia telangiectasia-mutated gene, IGV, Integrative Genomics Viewer, MDK, midkine, KEGG, Kyoto Encyclopedia of Genes and Genomes, PI, protease inhibitor, DDR, DNA damage response, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mrc1, mannose receptor C-type 1, NER, nucleotide excision repair, Glioma, Humans, PTEN, IF, immunofluorescence, GCM, glioma-conditioned medium, IDH, isocitrate dehydrogenase (NADP(+)), Tumor microenvironment, SSBR, DNA single-strand break repair, TMZ, temozolomide, Macrophages, medicine.disease, Mice, Inbred C57BL, body regions, 030104 developmental biology, Pen/Strep, penicillin/streptomycin, HR, homologous recombination, DAPI, 4′,6-diamidino-2-phenylindole, p53, 0301 basic medicine, ATR, Ataxia Telangiectasia And Rad3-Related Protein, qRT-PCR, Quantitative real-time reverse transcription-polymerase chain reaction, DAB, Diaminobenzidine, ChIP, Chromatin immunoprecipitation, Tumor Microenvironment, DNA damage repair, FA, Fanconi anemia, MGMT, O6-methylguanine-DNA methyltransferase, biology, LGG, lower grade glioma, TLS, trans-lesion synthesis, TP53, tumor protein P53, HRP, horseradish peroxidase, Cell Differentiation, Fizz1, found in inflammatory zone 1, SNP, single nucleotide polymorphism, TCGA, The Cancer Genome Atlas dataset, Cytokine, TNFA, tumor necrosis factor alpha, Female, Arg1, arginase 1, DNA repair, SWI/SNF, SWItch/Sucrose Non-Fermentable, MMR, mismatch repair, DMEM, Dulbecco's Modified Eagle Medium, AKT, protein kinase B, CCL2, C-C motif chemokine ligand 2, CGGA, The Chinese Glioma Genome Atlas dataset, C5, Complement C5, Cell Line, Glioma microenvironment, VEGFA, vascular endothelial growth factor A, FBS, fetal bovine serum, PBS, phosphate buffered saline, Cell Line, Tumor, medicine, Animals, ELISA, Enzyme-Linked Immunosorbent Assay, DR, direct repair, GO, gene ontology, ssGSEA, single sample gene set enrichment analysis, FC, fold change, PTEN, phosphatase and tensin homolog, EGFR, epidermal growth factor receptor, TBST, Tris-buffered Saline with Tween 20, NFκB, nuclear factor kappa B, biology.protein, Cancer research, GBM, glioblastoma, EM/PM classification, EGFR module / PDGFRA (platelet derived growth factor receptor A) -based molecular classification, Tumor Suppressor Protein p53

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae288d30336e455721de6bf5436f314bTest
https://doi.org/10.1016/j.ebiom.2019.01.067Test

6

The steroidal lactone withaferin A impedes T-cell motility by inhibiting the kinase ZAP70 and subsequent kinome signaling

المؤلفون: Siu Kwan Sze, Claudina Perez-Novo, Navin Kumar Verma, Wim Vanden Berghe, Chandra Sekhar Chirumamilla, Brandon Han Siang Wong, Mobashar Hussain Urf Turabe Fazil, Sunil Kumar

المساهمون: Lee Kong Chian School of Medicine (LKCMedicine), School of Biological Sciences, Interdisciplinary Graduate School (IGS), NTU Institute for Health Technologies

المصدر: The Journal of Biological Chemistry
Journal of biological chemistry

مصطلحات موضوعية: withaferin A, T-Lymphocytes, MAP, mitogen-activated protein, ICAM-1, intercellular adhesion molecule-1, migration, Biochemistry, TNF-α, tumor necrosis factor-α, chemistry.chemical_compound, Cell Movement, LFA-1, lymphocyte function-associated antigen-1, Kinome, ZAP70, zeta-chain-associated protein kinase 70, Phosphorylation, Cells, Cultured, Migration, ZAP-70 Protein-Tyrosine Kinase, PTK, protein tyrosine kinase, biology, kinome, Ligand (biochemistry), Intercellular Adhesion Molecule-1, Lymphocyte Function-Associated Antigen-1, Cell biology, Chemistry, rICAM-1, recombinant ICAM-1, Signal Transduction, Research Article, Integrin, Motility, SDF-1α, stromal cell-derived factor 1 α, STK, serine/threonine kinase, PBS, phosphate buffered saline, PKC, protein kinase C, Humans, Medicine [Science], Protein kinase A, Biology, Molecular Biology, Withanolides, Protein kinase C, Serine/threonine-specific protein kinase, Cell Biology, chemistry, Withaferin A, inflammation, DTT, dithiothreitol, TCR, T-cell receptor, NFκB, nuclear factor kappa B, biology.protein, IKKβ, I-kappa-B-kinase β, WFA, Withaferin A, Protein Kinases