المؤلفون: Tsai, Wei-Jiun, Lai, Yi-Hsin, Shi, Yong-An, Hammel, Michal, Duff, Anthony P, Whitten, Andrew E, Wilde, Karyn L, Wu, Chun-Ming, Knott, Robert, Jeng, U-Ser, Kang, Chia-Yu, Hsu, Chih-Yu, Wu, Jian-Li, Tsai, Pei-Jane, Chiang-Ni, Chuan, Wu, Jiunn-Jong, Lin, Yee-Shin, Liu, Ching-Chuan, Senda, Toshiya, Wang, Shuying

المصدر: Communications Biology. 6(1)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Foodborne Illness, Dental/Oral and Craniofacial Disease, Infectious Diseases, Aetiology, 2.2 Factors relating to the physical environment, Infection, Humans, Animals, Mice, Streptococcus, Streptolysins, Bacterial Proteins, NAD+ Nucleosidase, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7z96h51zTest

المؤلفون: Esteves, Beatriz Gonçalves

المساهمون: Friães, Ana Isabel de Aquino, Repositório da Universidade de Lisboa

مصطلحات موضوعية: Streptococcus pyogenes, NAD+ nucleosidase, Estreptolisina O, Estreptolisina S, emm89, Tese de mestrado - 2022, Domínio/Área Científica::Ciências Médicas

وصف الملف: application/pdf

الإتاحة: http://hdl.handle.net/10451/59456Test

المؤلفون: Rovira, Alexander R, Fin, Andrea, Tor, Yitzhak

المصدر: Journal of the American Chemical Society. 139(44)

مصطلحات موضوعية: Good Health and Well Being, ADP Ribose Transferases, Alcohol Dehydrogenase, Animals, Fluorescent Dyes, Humans, NAD, NAD+ Nucleosidase, Pyridines, Substrate Specificity, Swine, Thiazoles, Chemical Sciences, General Chemistry

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8tf240mxTest

المؤلفون: Hannah C. Feldman, Elisa Merlini, Carlos Guijas, Kristen E. DeMeester, Evert Njomen, Ellen M. Kozina, Minoru Yokoyama, Ekaterina Vinogradova, Holly T. Reardon, Bruno Melillo, Stuart L. Schreiber, Andrea Loreto, Jacqueline L. Blankman, Benjamin F. Cravatt

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(35)

مصطلحات موضوعية: Armadillo Domain Proteins, Proteomics, Cytoskeletal Proteins, Multidisciplinary, NAD+ Nucleosidase, Homeostasis, Cysteine, Axons

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2677a7e30b0fa14c560e8dc1e85639b4Test
https://pubmed.ncbi.nlm.nih.gov/35994671Test

المؤلفون: Leandro Lima, Stephen A. Goutman, Oscar Jackson, Henry Houlden, Menelaos Pipis, Mehrdad Asghari Estiar, Ziv Gan-Or, Kristel R. van Eijk, Rebecca Schüle, Ammar Al-Chalabi, Julia Kaye, Mary M. Reilly, Matthew B. Harms, Stephan Züchner, John Ravits, Jishu Xu, Johnathan Cooper-Knock, Queen Square Genomics, Jonathan Gilley, Matt C. Danzi, Alfredo Iacoangeli, Michael P. Coleman, Guy A. Rouleau

المساهمون: Gilley, Jonathan [0000-0002-9510-7956], Jackson, Oscar [0000-0002-1825-9331], Gan-Or, Ziv [0000-0003-0332-234X], Coleman, Michael [0000-0002-9354-532X], Apollo - University of Cambridge Repository

المصدر: eLife, Vol 10 (2021)
eLife 10, e70905 (2021). doi:10.7554/eLife.70905
eLife

مصطلحات موضوعية: Male, SARM1, metabolism [Nicotinamide Mononucleotide], neuroscience, Mice, Missense mutation, genetics, Biology (General), Amyotrophic lateral sclerosis, metabolism [NAD+ Nucleosidase], Nicotinamide Mononucleotide, Nicotinamide mononucleotide, Genetics, General Neuroscience, General Medicine, Middle Aged, metabolism [Motor Neuron Disease], genetics [Amyotrophic Lateral Sclerosis], Medicine, Female, genetics [Motor Neuron Disease], Research Article, Human, Adult, SARM1 protein, human, QH301-705.5, Science, Single-nucleotide polymorphism, Biology, NADase, General Biochemistry, Genetics and Molecular Biology, NAD+ Nucleosidase, genomics, medicine, Animals, Humans, SNP, human, Motor Neuron Disease, Allele, Alleles, Aged, risk allele, Armadillo Domain Proteins, General Immunology and Microbiology, Genetic heterogeneity, Activator (genetics), metabolism [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, Genetics and Genomics, medicine.disease, Cytoskeletal Proteins, ALS, ddc:600, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974b4c13efb4632c6d940a6b55aa0ddcTest
https://doi.org/10.7554/elife.70905Test

المؤلفون: Aolin Jia, Shijia Huang, Wen Song, Junli Wang, Yonggang Meng, Yue Sun, Lina Xu, Henriette Laessle, Jan Jirschitzka, Jiao Hou, Tiantian Zhang, Wenquan Yu, Giuliana Hessler, Ertong Li, Shoucai Ma, Dongli Yu, Jan Gebauer, Ulrich Baumann, Xiaohui Liu, Zhifu Han, Junbiao Chang, Jane E. Parker, Jijie Chai

المصدر: Science (New York, N.Y.). 377(6605)

مصطلحات موضوعية: Adenosine Diphosphate, DNA-Binding Proteins, Multidisciplinary, ADP-Ribosylation, Adenosine Triphosphate, NAD+ Nucleosidase, Arabidopsis Proteins, Arabidopsis, Intracellular Signaling Peptides and Proteins, Plant Immunity, Carboxylic Ester Hydrolases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47d157b221d0e35a95cae259fb75c4eTest
https://pubmed.ncbi.nlm.nih.gov/35857644Test

المؤلفون: Fan, Xiaolong, Valdimarsdottir, Gudrun, Larsson, Jonas, Brun, Ann, Magnusson, Mattias, Jacobsen, Sten Eirik W, ten Dijke, Peter, Karlsson, Stefan

المصدر: Journal of Immunology. 168(2):755-762

مصطلحات موضوعية: Cell Lineage : genetics, Cell Division : genetics, Cell Survival : genetics, Cells Cultured, Culture Media Serum-Free, Genetic Vectors : biosynthesis, Hela Cells, Hematopoietic Stem Cells : cytology : immunology : metabolism, Human, Immunophenotyping, NAD+ Nucleosidase : biosynthesis, K562 Cells, Signal Transduction : genetics : physiology, Support Non-U.S. Gov't, Transforming Growth Factor beta : antagonists & inhibitors : genetics : pharmacology : physiology, Transduction Genetic, Cell Cycle : genetics, Cattle, Autocrine Communication : genetics, Antigens Differentiation : biosynthesis, Antigens CD34 : biosynthesis, Animal, Adenoviridae : genetics, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Immunologi inom det medicinska området, Medical and Health Sciences, Basic Medicine, Immunology in the medical area

الوصول الحر: https://lup.lub.lu.se/record/106849Test
http://www.jimmunol.org/cgi/content/full/168/2/755Test
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11777969&dopt=AbstractTest

المؤلفون: Nilsson, Lars, Åstrand-Grundström, Ingbritt, Anderson, Kristina, Arvidsson, Ingrid, Hokland, Peter, Bryder, David, Kjeldsen, Lars, Johansson, Bertil, Hellström-Lindberg, Eva, Hast, Robert, Jacobsen, Sten Eirik W

المصدر: Blood. 100(1):259-267

مصطلحات موضوعية: Male, Human, Hematopoietic Stem Cells : pathology, Hematopoietic Stem Cells : immunology, Female, Clone Cells : pathology, Clone Cells : immunology, Pair 8, Chromosomes, Neoplastic : pathology, Cell Transformation, Neoplastic : genetics, Thy-1 : analysis, Antigens, Differentiation : analysis, CD34 : analysis, 80 and over, Aged, Middle Age, Myelodysplastic Syndromes : etiology, Myelodysplastic Syndromes : genetics, Myelodysplastic Syndromes : pathology, NAD+ Nucleosidase : analysis, Support, Non-U.S. Gov't, Trisomy, Tumor Stem Cells : immunology, Tumor Stem Cells : pathology, Medicin och hälsovetenskap, Klinisk medicin, Hematologi, Medical and Health Sciences, Clinical Medicine, Hematology

الوصول الحر: https://lup.lub.lu.se/record/108877Test
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12070035&dopt=AbstractTest
http://dx.doi.org/10.1182/blood-2001-12-0188Test

المؤلفون: Wentao Li, Lin Liang, Qianjin Liao, Yanling Li, Yanhong Zhou

المصدر: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 153

مصطلحات موضوعية: Pharmacology, CD4-Positive T-Lymphocytes, Membrane Glycoproteins, NAD+ Nucleosidase, Sirtuin 1, Humans, General Medicine, CD8-Positive T-Lymphocytes, NAD, ADP-ribosyl Cyclase 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cb9ef0e4981a4743a2b9b0beab9b7bTest
https://pubmed.ncbi.nlm.nih.gov/35834988Test

المؤلفون: Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte

المساهمون: Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologies appliquées (END-ICAP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Signalisation et physiopathologie cardiovasculaire (CARPAT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Infection et inflammation (2I), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Mayo Clinic [Rochester], Centre de recherche en Myologie – U974 SU-INSERM, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), BABARIT, Candice, Blanc 2013 - Arythmies dépendantes du calcium intracellulaire : mécanismes de la tachycardie ventriculaire catécholergique. - - ARyRthmia2013 - ANR-13-BSV1-0023 - Blanc 2013 - VALID, Idex Paris-Saclay - - IPS2011 - ANR-11-IDEX-0003 - IDEX - VALID, Mécanismes proarythmiques dépendant du sodium et du calcium - - NaCaR2019 - ANR-19-CE14-0031 - AAPG2019 - VALID, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Physiopathologie Animale et bioThérapie du muscle et du système nerveux (PAnTher), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Expertise en Anatomie Pathologique (APEX), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Mayo Clinic, This research has been supported by grants from CNRS, INSERM, and Paris-Saclay University. Funding for this work was provided by AFM-telethon grants(JMC, SDP, and AZ). AZ is a recipient of a PhD fellowship from the Paris-SudUniversity. This work was also partly funded by the Fondation de France (JMC),ANRs (NAD-Heart #17-CE17-0015-01to MM, and ANR-19-CE14-0031-01andANR-13-BSV1-0023-01to AMG), and NIH AG58812to ENC. INSERM U1180is amember of the Laboratory of Excellence LERMIT supported by a grant fromANR (ANR-10-LABX-33) under the program'Investissements d’Avenir'ANR-11-IDEX-0003-01. The authors thank the radiology department of the RaymondPoincare Hospital. The authors thank Sanofi for providing isatuximab. Theauthors thank Frances Lund for providing CD38/mice and the platform forimmortalization of human cells'MyoLine'from the Institut of Myology forproviding the DMD and healthy subject cell lines. Graphical abstract has beencreated with BioRender.com.ENC, J-MC, SP, and AZ have patents on the use of CD38inhibitors, ANR-13-BSV1-0023,ARyRthmia,Arythmies dépendantes du calcium intracellulaire : mécanismes de la tachycardie ventriculaire catécholergique.(2013), ANR-11-IDEX-0003,IPS,Idex Paris-Saclay(2011), ANR-19-CE14-0031,NaCaR,Mécanismes proarythmiques dépendant du sodium et du calcium(2019)

المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2022, 14 (5), pp.e12860. ⟨10.15252/emmm.202012860⟩
EMBO Molecular Medicine, 2022, 14 (5), pp.e12860. ⟨10.15252/emmm.202012860⟩

مصطلحات موضوعية: calcium, [SDV]Life Sciences [q-bio], NAD, ADP-ribosyl Cyclase 1, [SDV] Life Sciences [q-bio], Muscular Dystrophy, Duchenne, Mice, NAD+ Nucleosidase, Phenotype, NAD+, DMD, Mice, Inbred mdx, Animals, Humans, Molecular Medicine, Myocytes, Cardiac, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Muscle, Skeletal, cardiomyopathy, CD38, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f23ea7b5a55a6045963fe0fbb7e0cb4Test
https://doi.org/10.15252/emmm.202012860Test