المؤلفون: G. Ramazanov R., E. Kovaleva A., N. Shamalov A., Г. Рамазанов Р., Э. Ковалева А., Н. Шамалов А.

المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 10, № 4 (2021); 778-786 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 10, № 4 (2021); 778-786 ; 2541-8017 ; 2223-9022

مصطلحات موضوعية: ischemic stroke, cryptogenic stroke, oncologic disease, pathogenesis of ischemic stroke, ишемический инсульт, криптогенный инсульт, онкологическое заболевание, патогенез

وصف الملف: application/pdf

العلاقة: https://www.jnmp.ru/jour/article/view/1283/1005Test; Hart RG, Diener HC, Coutts SB, Easton JD, Granger CB, O’Donnell MJ, et al. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol. 2014;13(4):429–438. PMID: 24646875 https://doi.org/10.1016/S1474-4422Test(13)70310-7; Adams Jr HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35–41. PMID: 7678184 https://doi.org/10.1161/01.STR.24.1.35Test; Harloff A, Schlachetzki F. Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source. N Engl J Med. 2018;379(10):986– 987. https://doi.org/10.1056/NEJMoa1802686Test; Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S, et.al. Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. N Engl J Med. 2019;380(200):1906–1917. https://doi.org/10.1056/NEJMoa1813959Test; AtRial cardiopathy and antithrombotic drugs in prevention after cryptogenic stroke (ARCADIA). 2020. Available at: https://clinicaltrials.gov/ct2/show/NCT03192215Test. [Accessed Jul 09,2021]; Apixaban for Treatment of Embolic Stroke of Undetermined Source (ATTICUS). 2020. Available at: https://clinicaltrials.gov/ct2/show/NCT02427126Test [Accessed Jul 09.2021]; Ntaios G, Perlepe K, Lambrou D, Sirimarco G, Strambo D, Eskandari A, et al. Prevalence and overlap of potential embolic sources in patients with embolic stroke of undetermined source. J Am Heart Assoc. 2019;8: e012858. PMID: 31364451 https://doi.org/10.1161/JAHA.119.012858Test; Kim SJ, Park JH, Lee MJ, Park YG, Ahn MJ, Bang OY. Clues to occult cancer in patients with ischemic stroke. PLoS One. 2012;(9)7:e44959. PMID: 22984594 https://doi.org/10.1371/journal.pone.0044959Test; Graus F, Rogers LR, Posner JM. Cerebrovascular complication in patients with cancer. Medicine (Baltimore). 1985;64(1):16–35. PMID: 3965856 https://doi.org/10.1097/00005792-198501000-00002Test; Gon Y, Okazaki S, Terasaki Y, Sasaki T, Yoshimine T, Sakaguchi M, et al. Characteristics of cryptogenic stroke in cancer patients. Ann Clin Transl Neurol. 2016;3(4):280–287. PMID: 27081658 https://doi.org/10.1002/acn3.291Test; Chen PC, Muo CH, Lee YT, Yu YH, Sung FC. Lung cancer and incidence of stroke: a population – based cohort study. Stroke. 2011;42(11):3034–3039. PMID: 21903961 https://doi.org/10.1161/STROKEAHA.111.615534Test; Navi BB, Kasner SE, Elkind MSV, Cushman M, Bang OY, DeAngelis LM. Cancer and Embolic Stroke of Undetermined Source. Stroke. 2021;52(3):1121–1130. PMID: 33504187 https://doi.org/10.1161/STROKEAHA.120.032002Test; Welch HG, Kramer BS, Black WC. Epidemiologic signatures in cancer. N Engl J Med. 2019;381(14):1378–1386. PMID: 31577882 https://doi.org/10.1056/NEJMsr1905447Test; Howlader N, Forjaz G, Mooradian MJ, Meza R, Kong CY, Cronin KA, et al. The effect of advances in lung-cancer treatment on population mortality. N Engl J Med. 2020;383(7):640–649. PMID: 32786189 https://doi.org/10.1056/NEJMoa1916623Test; Navi BB, Howard G, Howard VJ, Zhao H, Judd SE, Elkind MSV, et al. New diagnosis of cancer and the risk of subsequent cerebrovascular events. Neurology. 2018;90(23):e2025–e2033. PMID: 29728524 https://doi.org/10.1212/WNL.0000000000005636Test; Navi BB, Reiner AS, Kamel H, Iadecola C, Okin PM, Elkind MSV, et al. Risk of arterial thromboembolism in patients with cancer. J Am Coll Cardiol. 2017;70(8):926–938. PMID: 28818202 https://doi.org/10.1016/j.jacc.2017.06.047Test; Navi BB, Singer S, Merkler AE, Cheng NT, Stone JB, Kamel H, et al. Cryptogenic subtype predicts reduced survival among cancer patients with ischemic stroke. Stroke. 2014;45(8):2292–2297. PMID: 24994717 https://doi.org/10.1161/STROKEAHA.114.005784Test; Hart RG, Catanese L, Perera KS, Ntaios G, Connolly SJ. Embolic stroke of undetermined source: a systematic review and clinical update. Stroke. 2017;48(4):867–872. PMID: 28265016 https://doi.org/10.1161/STROKEAHA.116.016414Test; Navi BB, DeAngelis LM, Segal AZ. Multifocal strokes as the presentation of occult lung cancer. J Neurooncol. 2007;85(3):307–309. PMID: 17611718 https://doi.org/10.1007/s11060-007-9419-yTest; Navi BB, Kawaguchi K, Hriljac I, Lavi E, DeAngelis LM, Jamieson DG. Multifocal stroke from tumor emboli. Arch Neurol. 2009;66(9):1174– 1175. PMID: 19752313 https://doi.org/10.1001/archneurol.2009.172Test; Grisold W, Oberndorfer S, Struhal W. Stroke and cancer: a review. Acta Neurol Scand. 2009;119(1):1–16. PMID: 18616624 https://doi.org/10.1111/j.1600-0404.2008.01059.xTest; Navi BB, Reiner AS, Kamel H, Iadecola C, Okin PM, Tagawa ST, et al. Arterial thromboembolic events preceding the diagnosis of cancer in older persons. Blood. 2019;133(8):781–789. PMID: 30578253 https://doi.orgTest/ 10.1182/blood-2018-06-860874; Selvik HA, Bjerkreim AT, Thomassen L, Waje-Andreassen U, Naess H, Kvistad CE. When to screen ischaemic stroke patients for cancer. Cerebrovasc Dis. 2018;45(1-2):42–47. PMID: 29402826 https://doi.org/10.1159/000484668Test; Gon Y, Sakaguchi M, Takasugi J, Kawano T, Kanki H, Watanabe A, et al. Plasma D-dimer levels and ischaemic lesions in multiple vascular regions can predict occult cancer in patients with cryptogenic stroke. Eur J Neurol. 2017;24(3):503–508. PMID: 28026909 https://doi.org/10.1111/ene.13234Test; Cocho D, Gendre J, Boltes A, Espinosa J, Ricciardi AC, Pons J, et al. Predictors of occult cancer in acute ischemic stroke patients. J Stroke Cerebrovasc Dis. 2015;24(6):1324–1328. PMID: 25881772 https://doi.orgTest/ 10.1016/j.jstrokecerebrovasdis.2015.02.006; Bang OY, Chung JW, Lee MJ, Seo WK, Kim GM, Ahn MJ, et al. CancerRelated Stroke: An Emerging Subtype of Ischemic Stroke with Unique Pathomechanisms. Stroke. 2020;22(1):1–10 PMID: 32027788 https://doi.org/10.5853/jos.2019.02278Test; Iguchi Y, Kimura K, Kobayashi K, Ueno Y, Inoue T. Ischaemic stroke with malignancy may often be caused by paradoxical embolism. J Neurol Neurosurg Psychiatry. 2006;77:1336–1339. PMID: 16847046 https://doi.org/10.1136/jnnp.2006.092940Test; Khorana AA, Dalal M, Lin J, Connolly GC. Incidence and predictors of venous thromboembolism (VTE) among ambulatory high-risk cancer patients undergoing chemotherapy in the United States. Cancer. 2013;119(3):648–655. PMID: 22893596 https://doi.org/10.1002/cncr.27772Test; Thompson CM, Rodgers LR. Analysis of the autopsy records of 157 cases of carcinoma of the pancreas with particular reference to the incidence of thromboembolism. Am J Med Sci. 1952;223:469–478. PMID: 14923654 https://doi.org/10.1097/00000441-195205000-00001Test; Volkova M, Russell R 3rd. Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment. Curr Cardiol Rev. 2011;7(4):214–220. PMID: 22758622. https://doi.org/10.2174/157340311799960645Test; Kim SG, Hong JM, Kim HY, Lee J, Chung PW, Park KY, et al. Ischemic stroke in cancer patients with and without conventional mechanisms: a multicenter study in Korea. Stroke. 2010;41:798–801. PMID: 20150545 https://doi.org/10.1161/STROKEAHA.109.571356Test; Schwarzbach CJ, Schaefer A, Ebert A, Held V, Bolognese M, Kablau M, et al. Stroke and cancer: the importance of cancer – associated hypercoagulation as a possible stroke etiology. Stroke. 2012;43:3029–3034. PMID: 22996958 https://doi.org/10.1161/STROKEAHA.112.658625Test; Sheng B, Fong MK, Chu YP, Cheong AP, Teng SK, Chu JP, et al. Stroke and cancer: misfortunes never come singularly. Int J Stroke. 2013;8:E30. PMID: 23879755 https://doi.org/10.1111/ijs.12071Test; Virchow R. Gesammalte Abhandlungen zur Wissenschaftlichen Medtzin. Frankfurt, Germany: Medinger Sohn; 1856.; Von Tempelhoff GF, Heilmann L, Hommel G, Pollow K. Impact of rheological variables in cancer. Semin Thromb Hemost. 2003;29(5):499– 513. PMID: 14631550 https://doi.org/10.1055/s-2003-44641Test; Humphreys WV, Walker A, Charlesworth D. Altered viscosity and yield stress in patients with abdominal malignancy: relationship to deep vein thrombosis. Br J Surg. 1976;63(7):559–561. PMID: 953452 https://doi.org/10.1002/bjs.1800630715Test; Blann AD, Dunmore S. Arterial and venous thrombosis in cancer patients. Cardiol Res Pract. 2011;2011:394740. PMID: 21403876 https://doi.org/10.4061/2011/394740Test; Stefan O, Vera N, Otto B, Heinz L, Wolfgang G. Stroke in cancer patients: a risk factor analysis. J Neurooncol. 2009;94(2):221–226. PMID: 19280119 https://doi.org/10.1007/s11060-009-9818-3Test; Bang OY, Chung JW, Lee MJ, Kim SJ, Cho YH, Kim GM, et al. Cancer cell-derived extracellular vesicles are associated with coagulopathy causing ischemic stroke via tissue factor-independent way: the OASISCANCER study. PLoS One. 2016;11:e0159170. PMID: 27427978 https://doi.org/10.1371/journal.pone.0159170Test; Chung JW, Cho YH, Ahn MJ, Lee MJ, Kim GM, Chung CS, et al. Association of cancer cell type and extracellular vesicles with coagulopathy in patients with lung cancer and stroke. Stroke. 2018;49(5):1282–1285. PMID: 2961026 https://doi.org/10.1161/STROKEAHA.118.020995Test; Thålin C, Demers M, Blomgren B, Wong SL, von Arbin M, von Heijne A, et al. NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation. Thromb Res. 2016;139:56–64. PMID: 26916297 https://doi.org/10.1016/j.thromres.2016.01.009Test; Park H, Kim J, Ha J, Hwang IG, Song TJ, Yoo J, et al. Histological features of intracranial thrombi in stroke patients with cancer. Ann Neurol. 2019;86(1):143–149. PMID: 31025392 https://doi.org/10.1002/ana.25495Test; Falanga A, Marchetti M, Vignoli A. Coagulation and cancer: biological and clinical aspects. J Thromb Haemost. 2013;11(2):223–233. PMID: 23279708 https://doi.org/10.1111/jth.12075Test; Navi BB, Mathias R, Sherman CP, Wolfe J, Kamel H, Tagawa ST, et al. Cancer-related ischemic stroke has a distinct blood mRNA expression profile. Stroke. 2019;50(11):3259–3264. PMID: 31510897 https://doi.org/10.1161/STROKEAHA.119.026143Test; Yoo J, Choi JK, Kim YD, Nam HS, Park H, Lee HS, et al. Outcome of Stroke Patients with Cancer and Nonbacterial Thrombotic Endocarditis. Stroke. 2020;22(2):245–253. PMID: 32635688 https://doi.org/10.5853/jos.2020.00619Test; Seok JM, Kim SG, Kim JW, Chung CS, Kim GM, Lee KH, et al. Coagulopathy and embolic signal in cancer patients with ischemic stroke. Ann Neurol. 2010;68:213–219. PMID: 32635688 https://doi.org/10.1002/ana.22050Test; Merkler AE, Navi BB, Singer S, Cheng NT, Stone JB, Kamel H, et al. Diagnostic yield of echocardiography in cancer patients with ischemic stroke. J Neurooncol. 2015;123:115–121. PMID: 25851114 https://doi.org/10.1007/s11060-015-1768-3Test; Hurrell H, Roberts-Thomson R, Prendergast BD. Non-infective endocarditis. Heart. 2020;106(13):1023–1029. PMID: 32376608 https://doi.org/10.1136/heartjnl-2019-315204Test; Vinter N, Christesen AMS, Fenger-Grøn M, Tjønneland A, Frost L. Atrial fibrillation and risk of cancer: a Danish population-based cohort study. J Am Heart Assoc. 2018;7(17):e009543. PMID: 30371150 https://doi.org/10.1161/JAHA.118.009543Test; Mitma AA, Varghese JG, Witt D, Zarich SW. Stroke and a valvular lesion in a patient with stage IV non-small cell lung cancer. BMJ Case Rep. 2016;2016:bcr2016215317. PMID: 27247207 https://doi.org/10.1136/bcr-2016-215317Test; Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420(6917):860– 867. PMID: 12490959 https://doi.org/10.1038/nature01322Test; Libby P. Inflammatory mechanisms: the molecular basis of inflammation and disease. Nutr Rev. 2007;65(12 Pt 2):S140–146. PMID: 18240538 https://doi.org/10.1111/j.1753-4887.2007.tb00352.xTest; Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res. 2005;96(9):939–949. PMID: 15890981 https://doi.org/10.1161/01.RES.0000163635.62927.34Test; Frayn K, Bernard S, Spalding K, Arner P. Adipocyte triglyceride turnover is independently associated with atherogenic dyslipidemia. J Am Heart Assoc. 2012;1:e003467. PMID: 23316323 https://doi.org/10.1161/JAHA.112.003467Test; Rodríguez-Iturbe B, Pons H, Quiroz Y, Johnson RJ. The immunological basis of hypertension. Am J Hypertens. 2014;27(11):1327–1337. PMID: 25150828 https://doi.org/10.1093/ajh/hpu142Test; Esposito K, Nappo F, Marfella R, Giugliano G, Giugliano F, Ciotola M, et al. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation. 2002;106(16):2067–2072. PMID: 12379575 https://doi.org/10.1161/01.cir.0000034509.14906.aeTest; Campen CJ, Kranick SM, Kasner SE, Kessler SK, Zimmerman RA, Lustig R, et al. Cranial irradiation increases risk of stroke in pediatric brain tumor survivors. Stroke. 2012;43:3035–3040. PMID: 22968468 https://doi.org/10.1161/STROKEAHA.112.661561Test; Xu J, Cao Y. Radiation-induced carotid artery stenosis: a comprehensive review of the literature. Interv Neurol. 2014;2(4):183–192. PMID: 25337087 https://doi.org/10.1159/000363068Test; Ramos-Casals M, Brahmer JR, Callahan MK, Flores-Chávez A, Keegan N, Khamashta MA, et al. Immune-related adverse events of checkpoint inhibitors. Nat Rev Dis Primers. 2020;6(1):38. PMID: 32382051 https://doi.org/10.1038/s41572-020-0160-6Test; Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. N Engl J. 2017;377(12):1119–1131. PMID: 28845751 https://doi.org/10.1056/NEJMoa1707914Test; Lee MJ, Chung JW, Ahn MJ, Kim S, Seok JM, Jang HM, et al. Hypercoagulability and mortality of patients with stroke and active cancer: the OASIS-CANCER study. J Stroke. 2017;19(1):77–87. PMID: 28030894 https://doi.org/10.5853/jos.2016.00570Test; Raskob GE, van Es N, Verhamme P, Carrier M, Di Nisio M, Garcia D, et al. Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med. 2018;378:615–624. PMID: 29231094 https://doi.org/10.1056/NEJMoa1711948Test; Agnelli G, Becattini C, Meyer G, Muñoz A, Huisman MV, Connors JM, et al.; Caravaggio Investigators. Apixaban for the treatment of venous thromboembolism associated with cancer. N Engl J Med. 2020;382(17):1599–1607. PMID: 32223112 https://doi.org/10.1056/NEJMoa1915103Test; Edoxaban for the treatment of coagulopathy in patients with active cancer and acute ischemic stroke: a pilot study. (ENCHASE Study) (ENCHASE). 2018. Available at: https://clinicaltrials.gov/ct2/show/NCT03570281Test [Accessed Jul 09.2021]; Carrier M, Lazo-Langner A, Shivakumar S, Tagalakis V, Zarychanski R, Solymoss S, et al. Screening for occult cancer in unprovoked venous thromboembolism. N Engl J Med. 2015; 373:697–704. PMID: 26095467 https://doi.org/10.1056/NEJMoa1506623Test; https://www.jnmp.ru/jour/article/view/1283Test

الإتاحة: https://doi.org/10.23934/2223-9022-2021-10-4-778-786Test
https://doi.org/10.1016/S1474-4422Test(13)70310-7
https://doi.org/10.1161/01.STR.24.1.35Test
https://doi.org/10.1056/NEJMoa1802686Test
https://doi.org/10.1056/NEJMoa1813959Test
https://doi.org/10.1161/JAHA.119.012858Test
https://doi.org/10.1371/journal.pone.0044959Test
https://doi.org/10.1097/00005792-198501000-00002Test
https://doi.org/10.1002/acn3.291Test
https://doi.org/10.1161/STROKEAHA.111.615534Test

المؤلفون: S. Boytsov A., M. Piradov A., M. Tanashyan M., I. Voznjouk A., M. Ezhov V., E. Oschepkova V., I. Sergienko V., N. Shamalov A., S. Yanishevskiy N., С. Бойцов А., М. Пирадов А., М. Танашян М., И. Вознюк A., М. Ежов В., Е. Ощепкова В., И. Сергиенко В., Н. Шамалов А., С. Янишевский Н.

المساهمون: The Meeting of Experts was supported by Novartis., Мероприятие проводилось при поддержке компании Новартис.

المصدر: Rational Pharmacotherapy in Cardiology; Vol 17, No 6 (2021); 927-930 ; Рациональная Фармакотерапия в Кардиологии; Vol 17, No 6 (2021); 927-930 ; 2225-3653 ; 1819-6446

مصطلحات موضوعية: acute cerebrovascular accident, lipid metabolism disorders, lipid-lowering therapy, interdisciplinary interaction, острое нарушение мозгового кровообращения, нарушения липидного обмена, гиполипидемическая терапия, междисциплинарное взаимодействие

وصف الملف: application/pdf

العلاقة: https://www.rpcardio.com/jour/article/view/2637/2270Test; Диагностика и коррекция нарушений липидного обмена с целью профилактики и лечения атеросклероза. Российские рекомендации VII пересмотр, 2020. Атеросклероз и Дислипидемии. 2020;1(38):7-44.; 2019 ESC/EAS guidelines for the management of dyslipidemias: lipid modification to reduce cardiovascular risk. Eur Heart J. 2020;41(1):111-88. DOI:10.1093/eurheartj/ehz455.; 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42(34):3227-37. DOI:10.1093/eurheartj/ehab484.; Milionis H, Ntaios G, Korompoki E, et al. Statin-based therapy for primary and secondary prevention of ischemic stroke: A meta-analysis and critical overview. Int J Stroke. 2020;15(4):377-84. DOI:10.1177/1747493019873594.; Ference BA, Ginsberg HN, Graham I, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017;38(32):2459-2472. DOI:10.1093/eurheartj/ehx144.; 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2021;52(7):e364-e467. DOI:10.1161/STR.0000000000000375.; Ишемический инсульт и транзиторная ишемическая атака у взрослых. Клинические рекомендации, 2020 [цитировано 14.11.2021]. Доступно на: https://cr.minzdrav.gov.ru/recomend/171_2Test.; Оганов Р.Г., Симаненков В.И., Бакулин И.Г., и др. Коморбидная патология в клинической практике. Алгоритмы диагностики и лечения. Кардиоваскулярная Терапия и Профилактика. 2019;18(1):5-66. DOI:10.15829/1728-8800-2019-1-5-66.; Приказ Министерства здравоохранения РФ от 9 января 2020 г. № 1н «Об утверждении перечня лекарственных препаратов для медицинского применения для обеспечения в течение одного года в амбулаторных условиях лиц, которые перенесли ОНМК, инфаркт миокарда, а также которым были выполнены аортокоронарное шунтирование, ангиопластика коронарных артерий со стентированием и катетерная абляция по поводу сердечно-сосудистых заболеваний» [цитировано 14.10.2021]. Доступно на: https://base.garant.ru/73462529Test/.; Мешков А.Н., Ершова А.И., Деев А.И., и др. Распределение показателей липидного спектра у мужчин и женщин трудоспособного возраста в Российской Федерации: результаты исследования ЭССЕ-РФ ЗА 2012-2014ГГ. Кардиоваскулярная Терапия и Профилактика. 2017;16(4):62-7. DOI:10.15829/1728-8800-2017-4-62-67.; Kuiper JG, Sanchez RJ, Houben E, et al. Use of Lipid-modifying Therapy and LDL-C Goal Attainment in a High-Cardiovascular-Risk Population in the Netherlands. Clin Ther. 2017;39(4):819-27. DOI:10.1016/j.clinthera.2017.03.001.; https://www.rpcardio.com/jour/article/view/2637Test

الإتاحة: https://doi.org/10.20996/1819-6446-2021-12-10Test
https://doi.org/10.1093/eurheartj/ehz455Test
https://doi.org/10.1093/eurheartj/ehab484Test
https://doi.org/10.1177/1747493019873594Test
https://doi.org/10.1093/eurheartj/ehx144Test
https://doi.org/10.1161/STR.0000000000000375Test
https://doi.org/10.15829/1728-8800-2019-1-5-66Test
https://doi.org/10.15829/1728-8800-2017-4-62-67Test
https://doi.org/10.1016/j.clinthera.2017.03.001Test
https://www.rpcardio.com/jour/article/view/2637Test

المؤلفون: D. Skrypnik V., K. Anisimov V., A. Botsina Yu., T. Kiseleva V., S. Grachev P., N. Shamalov A., E. Vasilyeva Yu., A. Shpektor V., Д. Скрыпник В., К. Анисимов В., А. Боцина Ю., Т. Киселева В., С. Грачев П., Н. Шамалов А., Е. Васильева Ю., А. Шпектор В.

المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 12, No 5 (2020); 9-17 ; Неврология, нейропсихиатрия, психосоматика; Vol 12, No 5 (2020); 9-17 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2020-5

مصطلحات موضوعية: ischemic stroke, cerebral artery occlusion, endovascular recanalization, thromboextraction, thromboaspiration, stroke network, metropolis, ишемический инсульт, окклюзия церебральных артерий, эндоваскулярная реканализация, тромбоэкстракция, тромбоаспирация, инсультная сеть, мегаполис

وصف الملف: application/pdf

العلاقة: https://nnp.ima-press.net/nnp/article/view/1443/1115Test; https://nnp.ima-press.net/nnp/article/view/1443/1136Test; Володюхин МЮ. Внутриартериальная реперфузионная терапия у пациентов с острым ишемическим инсультом. Медицинский совет. 2015;(10): 4-5.; Крылов ВВ, Володюхин МЮ. К вопросу об организации рентгенхирургической помощи пациентам с острым ишемическим инсультом. Нейрохирургия. 2017;(2):60-5.; Савелло АВ, Свистов ДВ. Внутрисосудистые вмешательства в острейшем периоде ишемического инсульта: результаты последних клинических исследований и практическая перспектива. Эндоваскулярная хирургия. 2015;2(3):15-23.; Анисимов КВ, Манчуров ВН, Скрыпник ДВ и др. Технические аспекты эндоваскулярного лечения ишемического инсульта. Эндоваскулярная хирургия. 2018;5(1):30- 42. doi:10.24183/2409-4080-2018-5-1-30-42; Saver JL. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015 Jun 11;372(24):2285-95. doi:10.1056/NEJMoa1415061. Epub 2015 Apr 17.; Jovin TG. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015 Jun 11;372(24):2296-306. doi:10.1056/NEJMoa1503780. Epub 2015 Apr 17.; Goyal M. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015 Mar 12;372(11):1019-30. doi:10.1056/NEJMoa1414905. Epub 2015 Feb 11.; Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015 Mar 12;372(11):1009-18. doi:10.1056/NEJMoa1414792. Epub 2015 Feb 11.; Berkhemer OA, Fransen PSS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015 Jan 1;372(1):11-20. doi:10.1056/NEJMoa1411587. Epub 2014 Dec 17.; Silverman IE, Beland DK, Chhabra J, McCullough LD. The «drip-and-ship» approach: starting IV t-PA for acute ischemic stroke at outside hospitals prior to transfer to a regional stroke center. Conn Med. Nov-Dec 2005;69(10):613-20.; Ismail M, Armoiry X, Tau N, et al. Mothership versus drip and ship for thrombectomy in patients who had an acute stroke: a systematic review and meta-analysis. J Neurointerv Surg. 2019 Jan;11(1):14-9. doi:10.1136/neurintsurg-2018-014249. Epub 2018 Oct 8.; Brekenfeld C, Goebell E, Schmidt H, et al. 'Drip-and-drive': shipping the neurointerventionalist to provide mechanical thrombectomy in primary stroke centers. J Neurointerv Surg. 2018 Oct;10(10):932-6. doi:10.1136/neurintsurg-2017-013634. Epub 2018 Feb 7.; Hastrup S, Damgaard D, Paaske Johnsen S, Andersen G. Prehospital Acute Stroke Severity Scale to Predict Large Artery Occlusion: Design and Comparison With Other Scales. Stroke. 2016 Jul;47(7):1772-6. doi:10.1161/STROKEAHA.115.012482. Epub 2016 Jun 7.; Kidwell CS, Starkman S, Eckstein M, et al. Identifying stroke in the field. Prospective validation of the Los Angeles prehospital stroke screen (LAPSS). Stroke. 2000 Jan;31(1):71-6. doi:10.1161/01.str.31.1.71; Powers WJ, Derdeyn CP, Biller J, et al. 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015 Oct;46(10):3020-35. doi:10.1161/STR.0000000000000074. Epub 2015 Jun 29.; Albers GW, Marks MP, Kemp S, et al. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med. 2018 Feb 22;378(8):708-18. doi:10.1056/NEJMoa1713973. Epub 2018 Jan 24.; Nogueira RG, Jadhav AP, Haussen DC, et al. for the DAWN Trial Investigators, Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018 Jan 4;378(1):11-21. doi:10.1056/NEJMoa1706442. Epub 2017 Nov 11.; Holmes DR, Hopkins LN. Interventional Cardiology and Acute Stroke Care Going Forward: JACC Review Topic of the Week. J Am Coll Cardiol. 2019 Apr 2;73(12):1483-90. doi:10.1016/j.jacc.2019.01.033; Widimsky P. Thrombectomy for stroke by cardiologists. Eur Heart J. 2018 Sep 1;39(33):3018. doi:10.1093/eurheartj/ehy442; Adeoye O, Albright KC, Carr BG, et al. Geographic access to acute stroke care in the United States. Stroke. 2014 Oct;45(10):3019-24. doi:10.1161/STROKEAHA.114.006293. Epub 2014 Aug 26.; White CJ. Acute Stroke Intervention: The Role of Interventional Cardiologists. J Am Coll Cardiol. 2019 Apr 2;73(12):1491-3. doi:10.1016/j.jacc.2018.12.071; Meng SW, Kuo RC, Yang HJ, et al. Recruiting an Acute Coronary Team to Perform Emergent Mechanical Thrombectomy in Acute Ischemic Stroke Patients: A Successful Case and Team Model in a Local Hospital. Acta Cardiol Sin. 2018 Jan;34(1):99-103. doi:10.6515/ACS.201801_34(1).20170730A; Petr W, Koznar B, Peisker T, et al. Feasibility and safety of direct catheter-based thrombectomy in the treatment of acute ischaemic stroke. Cooperation among cardiologists, neurologists and radiologists. Prospective registry PRAGUE-16. EuroIntervention. 2017;13(1):131-6. doi:10.4244/EIJ-D-16-00979; Guidera SA, Aggarwal S, Walton JD, et al. Mechanical Thrombectomy for Acute Ischemic Stroke in the Cardiac Catheterization Laboratory. JACC Cardiovasc Interv. 2020 Apr 13;13(7):884-91. doi:10.1016/j.jcin.2020.01.232; Kim BM, Baek JH, Heo JH, et al. Effect of Cumulative Case Volume on Procedural and Clinical Outcomes in Endovascular Thrombectomy. Stroke. 2019 May;50(5):1178- 83. doi:10.1161/STROKEAHA.119.024986; Nikoubashman O, Pauli F, Schürmann K, et al. Transfer of stroke patients impairs eligibility for endovascular stroke treatment. J Neuroradiol. 2018 Feb;45(1):49-53. doi:10.1016/j.neurad.2017.07.006. Epub 2017 Sep 18.; Froehler MT, Saver JL, Zaidat OO, et al. Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke). Circulation. 2017;136(24):2311-21. doi:10.1161/CIRCULATIONAHA.117.028920; McMeekin P, White P, James MA, et al. Estimating the number of UK stroke patients eligible for endovascular thrombectomy. Eur Stroke J. 2017 Dec;2(4):319-26. doi:10.1177/2396987317733343. Epub 2017 Oct 4.; Chia NH, Leyden JM, Newbury J, et al. Determining the Number of Ischemic Strokes Potentially Eligible for Endovascular Thrombectomy: A Population-Based Study. Stroke. 2016 May;47(5):1377-80. doi:10.1161/STROKEAHA.116.013165. Epub 2016 Mar 17.; Alegiani AC, Dorn F, Herzberg M, et al. Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. Int J Stroke. 2019 Jun;14(4):372-80. doi:10.1177/1747493018806199. Epub 2018 Oct 22.; Deb-Chatterji M, Pinnschmidt H, Flottmann F, et al. Stroke patients treated by thrombectomy in real life differ from cohorts of the clinical trials: a prospective observational study. BMC Neurol. 2020 Mar 5;20(1):81. doi:10.1186/s12883-020-01653-z; Jansen IGH, Mulder MJHL, Goldhoorn R-JB; MR CLEAN Registry investigators. Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry). BMJ. 2018 Mar 9;360:k949. doi:10.1136/bmj.k949; Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016 Apr 23;387(10029):1723-31. doi:10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18.; Goyal M, Simonsen CZ, Fisher M. Future trials on endovascular stroke treatment: the not-so-easy-to-pluck fruits. Neuroradiology. 2018 Feb;60(2):123-6. doi:10.1007/s00234-017-1966-0; https://nnp.ima-press.net/nnp/article/view/1443Test

الإتاحة: https://doi.org/10.14412/2074-2711-2020-5-9-17Test
https://doi.org/10.14412/2074-2711-2020-5Test
https://doi.org/10.24183/2409-4080-2018-5-1-30-42Test
https://doi.org/10.1056/NEJMoa1415061Test
https://doi.org/10.1056/NEJMoa1503780Test
https://doi.org/10.1056/NEJMoa1414905Test
https://doi.org/10.1056/NEJMoa1414792Test
https://doi.org/10.1056/NEJMoa1411587Test
https://doi.org/10.1136/neurintsurg-2018-014249Test
https://doi.org/10.1136/neurintsurg-2017-013634Test

المؤلفون: A. Boyko N., N. Shamalov A., O. Boyko V., E. Arinina E., O. Lyang V., E. Dubchenko A., A. Ivanov V., A. Kubatiev A., А. Бойко Н., Н. Шамалов А., О. Бойко В., Е. Аринина Е., О. Лянг В., Е. Дубченко А., А. Иванов В., А. Кубатиев А.

المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 12, No 3 (2020); 82-86 ; Неврология, нейропсихиатрия, психосоматика; Vol 12, No 3 (2020); 82-86 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2020-3

مصطلحات موضوعية: COVID-19, treatment, Angiitis, folic acid, лечение, Ангиовит, фолиевая кислота

وصف الملف: application/pdf

العلاقة: https://nnp.ima-press.net/nnp/article/view/1363/1054Test; https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020Test; https://www.cdc.gov/coronavirus/types.htmlTest; Zou X, Chen K, Zou J, et al. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Front Med.2020 Apr;14(2):185-92. doi:10.1007/s11684-020-0754-0. Epub 2020 Mar 12.; Liu F, Zhang Q, Huang C, et al. CT quantification of pneumonia lesions in early days predicts progression to severe illness in a cohort of COVID-19 patients. Theranostics. 2020 Apr 27; 10(12):5613-22. doi:10.7150/thno.45985. eCollection 2020.; Yang Z, Shi J, He Z, et al. Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients. Aging (Albany NY). 2020 Apr 10;12(7):6037-48. doi:10.18632/aging.102999. Epub 2020 Apr 10.; Serseg T, Benarous K, Yousfi M. Hispidin and Lepidine E: two Natural Compounds and Folic acid as Potential Inhibitors of 2019-novel coronavirus Main Protease (2019-nCoVMpro), molecular docking and SAR study. Curr Comput Aided Drug Des. 2020 Apr 21. doi:10.2174/1573409916666200422075440. Online ahead of print.; Дубченко ЕА, Иванов АВ, Бойко АН и др. Гипергомоцистеинемия и эндотелиальная дисфункция при сосудистых и аутоиммунных заболеваниях головного мозга. Журнал неврологии и психиатрии им. С.С.Корсакова. 2019;119(11):127-32.; https://static-1.rosminzdrav.ru/system/attachments/attaches/000/050/122/original/28042020_MR_COVID-19_v6.pdfTest; Bolander-Gouaille C. Focus on Homocysteine and the Vitamins involved in its metabolism. Springer Verlag France; 2002. 217 p.; Lentz SR, Haynes WG. Homocysteine: is it a clinically important cardiovascular risk factor? Cleve Clin J Med. 2004 Sep;71(9):729-34. doi:10.3949/ccjm.71.9.729.; Rasic-Markovic A, Stanojlovic O, Hrncic D, et al. The activity of erythrocyte and brain Na+/K+ and Mg2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration. Mol Cell Biochem.2009 Jul;327(1-2):39-45. doi:10.1007/s11010-009-0040-6. Epub 2009 Feb 18.; Raposo B, Rodriguez C, Martinez-Gonzalez J, Badimon L. High levels of homocysteine inhibit lysyl oxidase (LOX) and down-regulate LOX expression in vascular endothelial cells. Atherosclerosis. 2004 Nov;177(1):1-8. doi:10.1016/j.atherosclerosis.2004.06.015.; Sen U, Mishra PK, Tyagi N, Tyagi SC. Homocysteine to Hydrogen Sulfide or Hypertension. Cell Biochem Biophys. 20 1 0 Jul; 57(2-3):49-58. doi:10.1007/s12013-010-9079-y.; Li JJ, Li Q, Du HP, et al. Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter. Int J Mol Sci.2015 Jun 3;16(6):12560-77. doi:10.3390/ijms160612560.; Price BR, Wilcock DM, Weekman EM. Hyperhomocysteinemia as a Risk Factor for Vascular Contributions to Cognitive Impairment and Dementia. Front Aging Neurosci. 2018 Oct 31;10:350. doi:10.3389/fnagi.2018.00350. eCollection 2018.; Moretti R., Caruso P. The Controversial Role of Homocysteine in Neurology: From Labs to Clinical Practice. Int J Mol Sci. 2019 Jan 8;20(1):231. doi:10.3390/ijms20010231.; Henry BM, Vikse J, Benoit S, et al. Hyperinflammation and derangement of renin-angiotensin-aldosterone system in COVID-19: A novel hypothesis for clinically suspected hypercoagulopathy and microvascular immunothrombosis. Clin Chim Acta.2020 Aug; 507:167-73. doi:10.1016/j.cca.2020.04.027. Epub 2020 Apr 26.; Yao D, Sun NL. Hyperhomocysteinemia accelerates collagen accumulation in the adventitia of balloon-injured rat carotid arteries via angiotensin II type 1 receptor. Int J Mol Sci. 2014 Oct 27;15(11):19487-98. doi:10.3390/ijms151119487.; Li T, Yu B, Liu Z, et al. Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury. Nat Commun.2018 Jan 2;9(1):11. doi:10.1038/s41467-017-02401-7.; Shi L, Liu XY, Huang ZG, et al. Endogenous hydrogen sulfide and ERK1/2-STAT3 signaling pathway may participate in the association between homocysteine and hypertension. J Geriatr Cardiol. 2019 Nov;16(11):822-834. doi:10.11909/j.issn.1671-5411.2019.11.007.; https://nnp.ima-press.net/nnp/article/view/1363Test

الإتاحة: https://doi.org/10.14412/2074-2711-2020-3-82-86Test
https://doi.org/10.14412/2074-2711-2020-3Test
https://doi.org/10.1007/s11684-020-0754-0Test
https://doi.org/10.7150/thno.45985Test
https://doi.org/10.18632/aging.102999Test
https://doi.org/10.2174/1573409916666200422075440Test
https://doi.org/10.1007/s11010-009-0040-6Test
https://doi.org/10.1016/j.atherosclerosis.2004.06.015Test
https://doi.org/10.1007/s12013-010-9079-yTest
https://doi.org/10.3390/ijms160612560Test

المؤلفون: G. Ramazanov R., T. Magomedov A., L. Khamidova T., N. Rybalko V., S. Petrikov S., N. Shamalov A., Г. Рамазанов Р., Т. Магомедов А., Л. Хамидова Т., Н. Рыбалко В., С. Петриков С., Н. Шамалов А.

المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 8, № 3 (2019); 302-314 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 8, № 3 (2019); 302-314 ; 2541-8017 ; 2223-9022 ; 10.23934/2223-9022-2019-8-3

مصطلحات موضوعية: cryptogenic stroke, paradoxical embolism, open oval window, Fabry disease, aortic atheroma, криптогенный инсульт, парадоксальная эмболия, открытое овальное окно, болезнь Фабри, атерома аорты

وصف الملف: application/pdf

العلاقة: https://www.jnmp.ru/jour/article/view/691/689Test; https://www.jnmp.ru/jour/article/view/691/709Test; Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35–41. PMID: 7678184 https://doi.org/10.1161/01.str.24.1.35Test; Putaala J, Nieminen T, Haapaniemi E, Meretoja A, Rantanen K, Heikkinen N, et al. Undetermined stroke with an embolic pattern — a common phenotype with high early recurrence risk. Ann Med. 2015;47(5):406–413. PMID: 262242000 https://doi.org/10.3109/07853890.2015.1057612Test; Li L, Yiin GS, Geraghty OC, Schulz UG, Kuker W, Mehta Z, et al. Incidence, outcome, risk factors, and long-term prognosis of cryptogenic transient ischaemic attack and ischaemic stroke: a population-based study. Lancet Neurol. 2015;14(9):903–913. PMID: 26227434 https://doi.org/10.1016/S1474-4422Test(15)00132-5; Putaala J, Metso AJ, Metso TM, Konkola N, Kraemer Y, Haapaniemi E, et al. Analysis of 1008 consecutive patients aged 15 to 49 with first-ever ischemic stroke: the Helsinki young stroke registry. Stroke. 2009;40(4):1195–1203. PMID: 19246709 https://doi.org/10.1161/STROKEAHA.108.529883Test; Foulkes MA, Wolf PA, Price TR, Mohr JP, Hier DB. Stroke Data Bank: design, methods, and baseline characteristics. Stroke. 1988;19(5):547– 554. PMID: 3363589 https://doi.org/10.1161/01.str.19.5.547Test; Kunitz SC, Gross CR, Heyman A, Kase CS, Mohr JP, Price TR, et al. The pilot Stroke Data Bank: definition, design, and data. Stroke. 1984;15(4):740–746. PMID: 6464070 https://doi.org/10.1161/01.str.15.4.740Test; Perera KS, Vanassche T, Bosch J, Swaminathan B, Mundl H, Giruparajah M, et al. Global Survey of the Frequency of Atrial Fibrillation-Associated Stroke: Embolic Stroke of Undetermined Source Global Registry. Stroke. 2016;47(9):2197–2202. PMID: 27507860 https://doi.org/10.1161/STROKEAHA.116.013378Test; Bal S, Patel SK, Almekhlafi M, Modi J, Demchuk AM, Coutts SB. High Rate of Magnetic Resonance Imaging Stroke Recurrence in Cryptogenic Transient Ischemic Attack and Minor Stroke Patients. Stroke. 2012;43(12):3387–3388. PMID: 23033345 https://doi.org/10.1161/STROKEAHA.112.671172Test; Bang OY, Lee PH, Joo SY, Lee JS, Joo IS, Huh K. Frequency and mechanisms of stroke recurrence after cryptogenic stroke. Ann Neurol. 2003;54(2):227–234. PMID: 12891675 https://doi.org/10.1002/ana.10644Test; Ntaios G, Papavasileiou V, Milionis H, Makaritsis K, Vemmou A, Koroboki E, et al. Embolic Strokes of Undetermined Source in the Athens Stroke Registry: An Outcome Analysis. Stroke. 2015;46(8):2087–2093. PMID: 26159795 https://doi.org/10.1161/STROKEAHA.115.009334Test; Choe WC, Passman RS, Brachmann J, Morillo CA, Sanna T, Bernstein RA, et al. A Comparison of Atrial Fibrillation Monitoring Strategies After Cryptogenic Stroke (from the Cryptogenic Stroke and Underlying AF Trial). Am J Cardiol. 2015;116(6):889–893. PMID: 26183793 https://doi.org/10.1016/j.amjcard.2015.06.012Test; Ridker PM, Hennekens CH, Miletich JP. G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men. Circulation. 1999; 99(9): 999– 1004. PMID: 10051291 https://doi.org/10.1161/01.cir.99.8.999Test; Rojo-Martinez E, Sandín-Fuentes M, Calleja-Sanz AI, Cortijo-García E, García-Bermejo P, Ruiz-Piñero M, et al. High performance of an implantable Holter monitor in the detection of concealed paroxysmal atrial fibrillation in patients with cryptogenic stroke and a suspected embolic mechanism. Rev Neurol. 2013;57(6):251–257. PMID: 24008935; Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA, et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med. 2014;370(26):2478–2486. PMID: 24963567 https://doi.org/10.1056/NEJMoa1313600Test; Gladstone DJ, Spring M, Dorian P, Panzov V, Thorpe KE, Hall J, et al. Atrial Fibrillation in Patients with Cryptogenic Stroke. N Engl J Med. 2014;370(26):2467–2477. PMID: 24963566 https://doi.org/10.1056/NEJMoa1311376Test; Lethen H, Flachskampf FA, Schneider R, Sliwka U, Köhn G, Noth J, et al. Frequency of deep vein thrombosis in patients with patent foramen ovale and ischemic stroke or transient ischemic attack. Am J Cardiol. 1997;80(8):1066–1069. PMID: 9352979 https://doi.org/10.1016/s00029149Test(97)00604-8; Kamel H, Elkind MS, Bhave PD, Navi BB, Okin PM, Iadecola C, et al. Paroxysmal supraventricular tachycardia and the risk of ischemic stroke. Stroke. 2013;44(6):1550–1554. PMID: 23632982 https://doi.org/10.1161/STROKEAHA.113.001118Test; Tanne D, D’Olhaberriague L, Trivedi AM, Salowich-Palm L, Schultz LR, Levine SR. Anticardiolipin antibodies and mortality in patients with ischemic stroke: a prospective follow-up study. Neuroepidemiology. 2002;21(2):93–99. PMID: 11901279 https://doi.org/10.1159/000048623Test; Brambatti M, Connolly SJ, Gold MR, Morillo CA, Capucci A, Muto C, et al. Temporal relationship between subclinical atrial fibrillation and embolic events. Circulation. 2014;129(21):2094–2099. PMID: 24633881 https://doi.org/10.1161/CIRCULATIONAHA.113.007825Test; Glotzer TV, Daoud EG, Wyse DG, Singer DE, Ezekowitz MD, Hilker C, et al. The relationship between daily atrial tachyarrhythmia burden from implantable device diagnostics and stroke risk: the trends study. Circ Arrhythm Electrophysiol. 2009;2(5):474–480. PMID: 19843914 https://doi.org/10.1161/CIRCEP.109.849638Test; Keach JW, Bradley SM, Turakhia MP, Maddox TM. Early detection of occult atrial fibrillation and stroke prevention. Heart. 2015;101(14):1097– 1102. PMID: 25935765 https://doi.org/10.1136/heartjnl-2015-307588Test; Bernstein RA, Di Lazzaro V, Rymer MM, Passman RS, Brachmann J, Morillo CA, et al. Infarct topography and detection of atrial fibrillation in cryptogenic stroke: results from CRYSTAL AF. Cerebrovasc Dis. 2015;40(12):91–96. PMID: 26182860 https://doi.org/10.1159/000437018Test; Favilla CG, Ingala E, Jara J, Fessler E, Cucchiara B, Messé SR, et al. Predictors of finding occult atrial fibrillation after cryptogenic stroke. Stroke. 2015;46(5):1210–1215. PMID:25851771 https://doi.org/10.1161/STROKEAHA.114.007763Test; Miller DJ, Khan MA, Schultz LR, Simpson JR, Katramados AM, Russman AN, et al. Outpatient cardiac telemetry detects a high rate of atrial fibrillation in cryptogenic stroke. J Neurol Sci. 2013;324(1–2):57–61. PMID: 23102659 https://doi.org/10.1016/j.jns.2012.10.001Test; Kamel H, Soliman EZ, Heckbert SR, Kronmal RA, Longstreth WT Jr, Nazarian S, et al. P-wave morphology and the risk of incident ischemic stroke in the Multi-Ethnic Study of Atherosclerosis. Stroke. 2014;45(9):2786–2788 PMID: 25052322 https://doi.org/10.1161/STROKEAHA.114.006364Test; Yaghi S, Moon YP, Mora-McLaughlin C, Willey JZ, Cheung K, Di Tullio MR, et al. Left atrial enlargement and stroke recurrence: the Northern Manhattan Stroke Study. Stroke. 2015;46(6):1488–1493 PMID: 25908460 https://doi.org/10.1161/STROKEAHA.115.008711Test; Yaghi S, Boehme AK, Hazan R, Hod EA, Canaan A, Andrews HF, et al. Atrial cardiopathy and cryptogenic stroke: a cross-sectional pilot study. J Stroke Cerebrovasc Dis. 2015;25(1):110–114. PMID: 26476588 https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.09.001Test; Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, et al. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF consortium of community-based cohort studies. Europace. 2014;16(10):1426–1433. PMID: 25037055 https://doi.org/10.1093/europace/euu175Test; Llombart V, Antolin-Fontes A, Bustamante A, Giralt D, Rost NS, Furie K, et al. B-type natriuretic peptides help in cardioembolic stroke diagnosis: pooled data meta-analysis. Stroke. 2015;46(5):1187–1189. PMID: 25765726 https://doi.org/10.1161/STROKEAHA.114.008311Test; Yaghi S, Elkind MS. Cryptogenic stroke: a diagnostic challenge. Neurol Clin Pract. 2014;4(5):386–393. PMID: 25317376 https://doi.org/10.1212/CPJ.0000000000000086Test; De Bruijn SF, Agema WR, Lammers GJ, van der Wall EE, Wolterbeek R, Holman ER, et al. Transesophageal echocardiography is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke. Stroke. 2006;37(10):2531–2534. PMID: 16946152 https://doi.org/10.1161/01.STR.0000241064.46659.69Test; Srichai MB, Junor C, Rodriguez LL, Stillman AE, Grimm RA, Lieber ML, et al. Clinical, imaging, and pathological characteristics of left ventricular thrombus: a comparison of contrast-enhanced magnetic resonance imaging, transthoracic echocardiography, and transesophageal echocardiography with surgical or pathological validation. Am Heart J. 2006;152(1):75–84. PMID: 16824834 https://doi.org/10.1016/j.ahj.2005.08.021Test; Barkhausen J, Hunold P, Eggebrecht H, Schüler WO, Sabin GV, Erbel R, et al. Detection and characterization of intracardiac thrombi on MR imaging. AJR Am J Roentgenol. 2002;179(6):1539–1544. PMID: 12438051 https://doi.org/10.2214/ajr.179.6.1791539Test; Bahrer A, Mowla A, Kodali S, Polsani VR, Nabi F, Nagueh SF, et al. Cardiac MRI improves identification of etiology of acute ischemic stroke. Cerebrovasc Dis. 2014;37(4):277–284. PMID: 24819735 https://doi.org/10.1159/000360073Test; Fisher CM. Occlusion of the internal carotid artery. Arch Neurol Psychiatry. 1951;65(5):346–377. PMID: 13418970; Saam T, Underhill HR, Chu B, Takaya N, Cai J, Polissar NL, et al. Prevalence of American Heart Association type VI carotid atherosclerotic lesions identified by magnetic resonance imaging for different levels of stenosis as measured by duplex ultrasound. J Am Coll Cardiol. 2008;51(10):1014– 1021. PMID: 18325441 https://doi.org/10.1016/j.jacc.2007.10.054Test; Freilinger TM, Schindler A, Schmidt C, Grimm J, Cyran C, Schwarz F, et al. Prevalence of Nonstenosing, Complicated Atherosclerotic Plaques in Cryptogenic Stroke. JACC Cardiovasc Imaging. 2012;5(4):397–405. PMID: 22498329 https://doi.org/10.1016/j.jcmg.2012.01.012Test; Winter WJ Jr. Atheromatous emboli; a cause of cerebral infarction; report of two cases. AMA Arch Pathol. 1957;64(2):137–142. PMID: 13443604; Di Tullio MR, Sacco RL, Gersony D, Nayak H, Weslow RG, Kargman DE, et al. Aortic atheromas and acute ischemic stroke: A transesophageal echocardiographic study in an ethnically mixed population. Neurology. 1996;46(6):1560–1566. PMID: 8649549 https://doi.org/10.1212/wnl.46.6.1560Test; Amarenco P, Duyckaerts C, Tzourio C, Hénin D, Bousser MG, Hauw JJ. The prevalence of ulcerated plaques in the aortic arch in patients with stroke. N Engl J Med. 1992;326:221. PMID: 1727976 https://doi.org/10.1056/NEJM199201233260402Test; Knebel F, Masuhr F, von Hausen W, Walde T, Dreger H, Raab V, et al. Transesophageal echocardiography in patients with cryptogenic cerebral ischemia. Cardiovasc Ultrasound. 2009;7:15. PMID: 19327171 https://doi.org/10.1186/1476-7120-7-15Test; Okuma H, Kitagawa Y, Yasuda T, Tokuoka K, Takagi S. Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome. Int J Med Sci. 2009;7(1):15– 18. PMID: 20046230 https://doi.org/10.7150/ijms.7.15Test; Rundek T, Di Tullio MR, Sciacca RR, Titova IV, Mohr JP, Homma S, et al. Association between large aortic arch atheromas and high-intensity transient signals in elderly stroke patients. Stroke. 1999;30(12):2683– 2686. PMID: 10582997 https://doi.org/10.1161/01.str.30.12.2683Test; The French Study of Aortic Plaques in Stroke Group; Amarenco P, Cohen A, Hommel M. Atherosclerotic disease of the aortic arch as a risk factor for recurrent ischemic stroke. N Engl J Med. 1996;334(19):1216–1221. PMID: 8606716 https://doi.org/10.1056/NEJM199605093341902Test; Stone DA, Hawke MW, LaMonte M, Kittner SJ, Acosta J, Corretti M, et al. Ulcerated atherosclerotic plaques in the thoracic aorta are associated with cryptogenic stroke: a multiplane transesophageal echocardiographic study. Am Heart J. 1995;130(1):105–108. PMID: 7611098 https://doi.org/10.1016/0002-8703Test(95)90243-0; Di Tullio MR, Russo C, Jin Z, Sacco RL, Mohr JP, Homma S. Aortic arch plaques and risk of recurrent stroke and death. Circulation. 2009;119(17):2376–2382. PMID: 19380621 https://doi.org/10.1161/CIRCULATIONAHA.108.811935Test; Kamel H, Gialdini G, Baradaran H, Giambrone AE, Navi BB, Lerario MP, et al. Cryptogenic Stroke and Nonstenosing Intracranial Calcified Atherosclerosis. J Stroke Cerebrovasc Dis. 2017;26(4):863–870. PMID: 27887791 https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.10.035Test; Huang YN, Gao S, Li SW, Huang Y, Li JF, Wong KS, et al. Vascular lesions in Chinese patients with transient ischemic attacks. Neurology. 1997;48(2):524–525. PMID: 9040750 https://doi.org/10.1212/wnl.48.2.524Test; Weber R, Kraywinkel K, Diener HC, Weimar C. Symptomatic intracranial atherosclerotic stenoses: prevalence and prognosis in patients with acute cerebral ischemia. Cerebrovasc Dis. 2010;30(2):188–193. PMID: 20588014 https://doi.org/10.1159/000317107Test; Cohnheim J. Vorlesungen über allgemeine Pathologie. Ein Handbuch für Arzte und Studierende. Berlin: Hirschwald, 1878.; Homma S, Sacco RL, Di Tullio MR, Sciacca RR, Mohr JP. Effect of medical treatment in stroke patients with patent foramen ovale patent foramen ovale in Cryptogenic Stroke Study. Circulation. 2002;105(22):2625–2631. PMID: 12045168 https://doi.org/10.1161/01.cir.0000017498.88393.44Test; Alsheikh-Ali AA, Thaler DE, Kent DM. Patent foramen ovale in cryptogenic stroke incidental or pathogenic? Stroke. 2009;40(7):2349–2355. PMID: 19443800 https://doi.org/10.1161/STROKEAHA.109.547828Test; Hamedani AG, Cole JW, Mitchell BD, Kittner SJ. Meta-analysis of factor V Leiden and ischemic stroke in young adults: the importance of case ascertainment. Stroke. 2010;41(8):1599–1603. PMID: 20616326 https://doi.org/10.1161/STROKEAHA.110.581256Test; Overell JR, Bone I, Lees KR. Interatrial septal abnormalities and stroke: a meta-analysis of case-control studies. Neurology. 2000;55(8):1172– 1179. PMID: 11071496 https://doi.org/10.1212/wnl.55.8.1172Test; Wessler BS, Thaler DE, Ruthazer R, Weimar C, Di Tullio MR, Elkind MS, et al. Transesophageal echocardiography in cryptogenic stroke and patent foramen ovale analysis of putative high-risk features from the risk of paradoxical embolism database. Circ Cardiovasc Imaging. 2014;7(1):125–131. PMID: 24214884 https://doi.org/10.1161/CIRCIMAGING.113.000807Test; Liberman AL, Daruwalla VJ, Collins JD, Maas MB, Botelho MP, Ayache JB, et al. Diagnostic yield of pelvic magnetic resonance venography in patients with cryptogenic stroke and patent foramen ovale. Stroke. 2014;45(8):2324–2329. PMID: 24938843 https://doi.org/10.1161/STROKEAHA.114.005539Test; Osgood M, Budman E, Carandang R, Goddeau RP Jr, Henninger N. Prevalence of pelvic vein pathology in patients with cryptogenic stroke and patent foramen ovale undergoing MRV pelvis. Cerebrovasc Dis. 2015;39(3–4):216–223. PMID: 257917 https://doi.org/10.1159/000376613Test; Cramer SC, Rordorf G, Maki JH, Kramer LA, Grotta JC, Burgin WS, et al. Increased pelvic vein thrombi in cryptogenic stroke results of the Paradoxical Emboli From Large Veins in Ischemic Stroke (PELVIS) Study. Stroke. 2004;35(1):46–50. PMID: 14657451 https://doi.org/10.1161/01.STR.0000106137.42649.ABTest; Kent DM, Ruthazer R, Weimar C, Mas JL, Serena J, Homma S, et al. An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke. Neurology. 2013;81(7):619–625. PMID: 23864310 https://doi.org/10.1212/WNL.0b013e3182a08d59Test; Loscalzo J. Paradoxical embolism: clinical presentation, diagnostic strategies, and therapeutic options. Am Heart J. 1986;112(1):141–145. PMID: 3728270; Tanislav C, Puille M, Pabst W, Reichenberger F, Grebe M, Nedelmann M, et al. High Frequency of Silent Pulmonary Embolism in Patients With Cryptogenic Stroke and Patent Foramen Ovale. Stroke. 2011;42(3):822– 824. PMID: 21257827 https://doi.org/10.1161/STROKEAHA.110.601575Test; Wu LA, Malouf JF, Dearani JA, Hagler DJ, Reeder GS, Petty GW, et al. Patent Foramen Ovale in Cryptogenic Stroke: current understanding and management options. Arch Intern Med. 2004;164(9):950–956. PMID: 15136302 https://doi.org/10.1001/archinte.164.9.950Test; Yanagawa S, Ito N, Arima K, Ikeda S. Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy. Neurology. 2002;58(5):817–820. PMID: 11889251 https://doi.org/10.1212/wnl.58.5.817Test; Chan MY, Andreotti F, Becker RC. Hypercoagulable states in cardiovascular disease. Circulation. 2008;118(22):2286–97. PMID: 19029477 https://doi.org/10.1161/CIRCULATIONAHA.108.778837Test; Schuchlenz HW, Weihs W, Horner S, Quehenberger F. The association between the diameter of a patent foramen ovale and the risk of embolic cerebrovascular events. Am J Med. 2000;109(6):456–462. PMID: 11042234 https://doi.org/10.1016/s0002-9343Test(00)00530-1; Kimura K, Minematsu K, Wada K, Yasaka M, Tagaya M, Kuribayashi S, et al. Transcranial Doppler of a paradoxical brain embolism associated with a pulmonary arteriovenous fistula. AJNR Am J Neuroradiol. 1999;20(10):1881–1884. PMID: 10588113; Churton T. Multiple aneurysms of the pulmonary artery. Br Med J. (Clin Res Ed.). 1897; 1: 1223.; Westerman LP, Green D, Gilman-Sachs A, Beaman K, Freels S, Boggio L, et al. Antiphospholipid antibodies, proteins C and S, and coagulation changes in sickle cell disease. J Lab Clin Med. 1999;134(4):352–362. PMID: 10521081; McDermott S, Oliveira G, Ergül E, Brazeau N, Wicky S, Oklu R. MayThurner syndrome: can it be diagnosed by a single MR venography study. Diagn Interv Radiol. 2013;19(1):44–48. PMID: 22801870 https://doi.org/10.4261/1305-3825.DIR.5939-12.1Test; Crowther MA, Ginsberg JS, Julian J, Denburg J, Hirsh J, Douketis J, et al. A Comparison of Two Intensities of Warfarin for the Prevention of Recurrent Thrombosis in Patients with the Antiphospholipid Antibody Syndrome. N Engl J Med. 2003;349(12):1133–1138. PMID: 13679527 https://doi.org/10.1056/NEJMoa035241Test; Kiernan TJ, Yan BP, Cubeddu RJ, Rengifo-Moreno P, Gupta V, Inglessis I, et al. May-Thurner syndrome in patients with cryptogenic stroke and patent foramen ovale: an important clinical association. Stroke. 2009;40(4):1502–1504. PMID: 19182088 https://doi.org/10.1161/STROKEAHA.108.527366Test; Varona JF, Guerra JM, Bermejo F, Molina JA, Gomez de la Cámara A. Causes of ischemic stroke in young adults, and evolution of the etiological diagnosis over the long term. Eur Neurol. 2007;57(4):212– 218. PMID: 17268202 https://doi.org/10.1159/000099161Test; Nagel MA, Cohrs RJ, Mahalingam R, Wellish MC, Forghani B, Schiller A, et al. The Varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features. Neurology. 2008;70(11):853–860. PMID: 18332343 https://doi.org/10.1212/01.wnl.0000304747.38502.e8Test; Caplan LR. Dissections of brain-supplying arteries. Nat Clin Pract Neurol. 2008;4(1):34–42. PMID: 18199995 https://doi.org/10.1038/ncpneuro0683Test; Gilden D, Cohrs RJ, Mahalingam R, Nagel MA. Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment. Lancet Neurol. 2009;8(8):731–740. PMID: 19608099 https://doi.org/10.1016/S1474-4422Test(09)70134-6; Askalan R, Laughlin S, Mayank S, Chan A, MacGregor D, Andrew M, et al. Chickenpox and stroke in childhood: a study of frequency and causation. Stroke. 2001;32(6):1257–1262. PMID: 11387484 https://doi.org/10.1161/01.str.32.6.1257Test; Kang JH, Ho JD, Chen YH, Lin HC. Increased risk of stroke after a herpes zoster attack: a population-based follow-up study. Stroke. 2009;40(11):3443–3448. PMID:19815828 https://doi.org/10.1161/STROKEAHA.109.562017Test; Nouh A, Hussain M, Mehta T, Yaghi S. Embolic Strokes of Unknown Source and Cryptogenic Stroke: Implications in Clinical Practice. Front Neurol. 2016;7:37. PMID: 27047443 https://doi.org/10.3389/fneur.2016.00037Test; Sajedi PI, Gonzalez JN, Cronin CA, Kouo T, Steven A, Zhuo J, et al. Carotid Bulb Webs as a Cause of “Cryptogenic” Ischemic Stroke. AJNR Am J Neuroradiology. 2017;38(7):1399–1404. PMID: 28495950 https://doi.org/10.3174/ajnr.A5208Test; Amarenco P, Davis S, Jones EF, Cohen AA, Heiss WD, Kaste M, et al. The Aortic Arch Related Cerebral Hazard Trial Investigators. Clopidogrel Plus Aspirin Versus Warfarin in Patients With Stroke and Aortic Arch Plaques. Stroke. 2014;45(5):1248–1257. PMID:24699050 https://doi.org/10.1161/STROKEAHA.113.004251Test; Ohene-Frempong K, Weiner SJ, Sleeper LA, Miller ST, Embury S, Moohr JW, et al. Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91(1):288–294. PMID: 9414296; Koshy M, Thomas C, Goodwin J. Vascular lesions in the central nervous system in sickle cell disease (neuropathology). J Assoc Acad Minor Phys. 1990;1(3):71–78. PMID: 2136620; Razdan S, Strouse JJ, Naik R, Lanzkron S, Urrutia V, Resar JR, et al. Patent Foramen Ovale in Patients with Sickle Cell Disease and Stroke: Case Presentations and Review of the Literature. Case Rep Hematol. 2013;2013: 516705. PMID: 23956892 https://doi.org/10.1155/2013/516705Test; Bertina R.M., Koeleman B.P., Koster T., Rosendaal FR, Dirven RJ, de Ronde H, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature. 1994;369(6475):64–67. PMID: 8164741 https://doi.org/10.1038/369064a0Test; Casas JP, Bautista LE, Smeeth L, Sharma P, Hingorani AD. Homocysteine and stroke: evidence on a causal link from mendelian randomisation. Lancet. 2005; 365(9455): 224–232. PMID: 15652605 https://doi.org/10.1016/S0140-6736Test(05)17742-3; Morris JG, Singh S, Fisher M. Testing for inherited thrombophilias in arterial stroke: can it cause more harm than good? Stroke. 2010;41(12):2985–2990. PMID: 20947844 https://doi.org/10.1161/STROKEAHA.110.595199Test; Aznar J, Mira Y, Vayб A, Corella D, Ferrando F, Villa P, et al. Factor V Leiden and prothrombin G20210A mutations in young adults with cryptogenic ischemic stroke. Thromb Haemost. 2004;91(5):1031–1034. PMID:15116266 https://doi.org/10.1160/TH03-11-0690Test; De Stefano V, Chiusolo P, Paciaroni K, Casorelli I, Rossi E, Molinari M, et al. Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients. Blood. 1998; 91(10): 3562–3565. PMID: 9572989; Casas JP, Hingorani AD, Bautista LE, Sharma P. Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. Arch Neurol. 2004;61(11):1652–1661. PMID: 15534175 https://doi.org/10.1001/archneur.61.11.1652Test; Holmes MV, Newcombe P, Hubacek JA, Sofat R, Ricketts SL, Cooper J, et al. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Lancet. 2011;378(9791):584–594. PMID: 21803414 https://doi.org/10.1016/S0140-6736Test(11)60872-6; Kelly PJ, Rosand J, Kistler JP, Shih VE, Silveira S, Plomaritoglou A, et al. Homocysteine, MTHFR 677C→T polymorphism, and risk of ischemic stroke: results of a meta-analysis. Neurology. 2002;59(4):529–536. PMID: 12196644 https://doi.org/10.1212/wnl.59.4.529Test; Kim RJ, Becker RC. Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies. Am Heart J. 2003;146(6):948–957. PMID: 14660985 https://doi.org/10.1016/S0002-8703Test(03)00519-2; Pezzini A, Grassi M, Del Zotto E, Lodigiani C, Ferrazzi P, Spalloni A, et al. Common genetic markers and prediction of recurrent events after ischemic stroke in young adults. Neurology. 2009;73(9):717–723. PMID: 19720979 https://doi.org/10.1212/WNL.0b013e3181b59aafTest; Patel ML, Sachan R, Seth G. Combined deficiency of proteins C and S: ischaemic stroke in young individuals. BMJ Case Reports. 2013;2013: pii: bcr2012008016. PMID: 24334463 https://doi.org/10.1136/bcr-2012008016Test; Brey RL, Stallworth CL, McGlasson DL, Wozniak MA, Wityk RJ, Stern BJ, et al. Antiphospholipid antibodies and stroke in young women. Stroke. 2002;33(10):2396–2400. PMID: 12364727 https://doi.org/10.1161/01.str.0000031927.25510.d1Test; Levine SR, Brey RL, Tilley BC, Thompson JL, Sacco RL, Sciacca RR, et al. Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke. JAMA. 2004;291(5):576–584. PMID: 14762036 https://doi.org/10.1001/jama.291.5.576Test; Anticardiolipin antibodies are an independent risk factor for first ischemic stroke. The Antiphospholipid Antibodies in Stroke Study (APASS) Group. Neurology. 1993;43(10):2069–2073. PMID: 8413969; Tohgi H, Takahashi H, Kashiwaya M, Watanabe K, Hayama K. The anticardiolipin antibody in elderly stroke patients: its effects on stroke types, recurrence, and the coagulation-fibrinolysis system. Acta Neurol Scand. 1994;90(2):86–90. PMID: 7801744; Levine SR, Salowich-Palm L, Sawaya KL, Perry M, Spencer HJ, Winkler HJ, et al. IgG anticardiolipin antibody titer > 40 GPL and the risk of subsequent thrombo-occlusive events and death: a prospective cohort study. Stroke. 1997;28(9):1660–1665. PMID: 9303006 https://doi.org/10.1161/01.str.28.9.1660Test; Nencini P, Baruffi MC, Abbate R, Massai G, Amaducci L, Inzitari D. Lupus anticoagulant and anticardiolipin antibodies in young adults with cerebral ischemia. Stroke. 1992;23(2):189–193. PMID: 1561646 https://doi.org/10.1161/01.str.23.2.189Test; Karttunen V, Alfthan G, Hiltunen L, Rasi V, Kervinen K, Kesäniemi YA, et al. Risk factors for cryptogenic ischaemic stroke. Eur J Neurol. 2002;9(6):625–632 PMID: 12453078; Vayá A, Ejarque I, Tembl J, Corella D, Laiz B. Hyperhomocysteinemia, obesity and cryptogenic stroke. Clin Hemorheol Microcirc. 2011;47(1):53– 58. PMID: 21321408 https://doi.org/10.3233/CH-2010-1365Test; Eikelboom JW, Hankey GJ, Anand SS, Lofthouse E, Staples N, Baker RI. Association between high homocyst(e)ine and ischemic stroke due to largeand small-artery disease but not other etiologic subtypes of ischemic stroke. Stroke. 2000;31(5):1069–1075. PMID: 10797167 https://doi.org/10.1161/01.str.31.5.1069Test; Klatsky AL, Armstrong MA, Friedman GD, Sidney S. Alcohol drinking and risk of hemorrhagic stroke. Neuroepidemiology. 2002;21(3):115– 122. PMID: 12006774 https://doi.org/10.1159/000054808Test; Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA. 1993;270(22):2693–2698. PMID: 8133587 https://doi.org/10.1001/jama.1993.03510220049033Test; Weintraub G, Sprecace G. Paroxysmal atrial fibrillation and cerebral embolism with apparently normal heart. N Engl J Med. 1958;259(18):875– 876. PMID: 13590468 https://doi.org/10.1056/NEJM195810302591807Test; Hassan A, Sham PC, Markus HS. Planning genetic studies in human stroke Sample size estimates based on family history data. Neurology. 2002;58(10):1483–1488. PMID: 12034783 https://doi.org/10.1212/wnl.58.10.1483Test; Chabriat H, Levy C, Taillia H, Iba-Zizen MT, Vahedi K, Joutel A, et al. Patterns of MRI lesions in CADASIL. Neurology. 1998;51(2):452–457. PMID: 9710018 https://doi.org/10.1212/wnl.51.2.452Test; O’Sullivan M, Jarosz JM, Martin RJ, Deasy N, Powell JF, Markus HS. MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL. Neurology. 2001;56(5):628–634. PMID: 11245715 https://doi.org/10.1212/wnl.56.5.628Test; Fukutake T. Young-adult-onset hereditary subcortical vascular dementia: cerebral autosomal recessive arteriosclerosis with subcortical infarcts and leukoencephalopathy (CARASIL). Rinsho Shinkeigaku. 1999; 39(1): 50–52. PMID: 10377800; Star M, Gill R, Bruzzone M, De Alba F, Schneck MJ, Biller J. Do not forget Susac syndrome in patients with unexplained acute confusion. J Stroke Cerebrovasc Dis. 2015;24(4):e93–95. PMID: 25680663 https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.11.028Test; Jen J, Cohen AH, Yue Q, Stout JT, Vinters HV, Nelson S, et al. Hereditary endotheliopathy with retinopathy, nephropathy, and stroke (HERNS). Neurology. 1997;49(5):1322–1330. PMID: 9371916 https://doi.org/10.1212/wnl.49.5.1322Test; Olin JW, Kaufman JA, Bluemke DA, Bonow RO, Gerhard MD, Jaff MR, et al. Atherosclerotic Vascular Disease Conference: writing Group IV: imaging. Circulation. 2004;109(21):2626-2633. PMID:15173045 https://doi.org/10.1161/01.CIR.0000128521.02390.72Test; Desnick RJ, Ioannou YA, Eng CM. Galactosidase a deficiency: fabry disease. In: Scriver CR, Beaudet AL, Sly WS, Valle D. (eds.) The Metabolic and Molecular Bases of Inherited Disease. 8th ed. New York, NY: McGraw Hill; 2001. p.3733–3774.; Moore DF, Kaneski CR, Askari H, Schiffmann R. The cerebral vasculopathy of Fabry disease. J Neurol Sci. 2007;257(1–2):258–263. PMID: 17362993 https://doi.org/10.1016/j.jns.2007.01.053Test; Desnick RJ, Brady R, Barranger J, Collins AJ, Germain DP, Goldman M, et al. Fabry disease, an under-recognized multisystemic disorder: expert recommendations for diagnosis, management, and enzyme replacement therapy. Ann Intern Med. 2003;138(4):338–346. PMID: 1258533 https://doi.org/10.7326/0003-4819-138-4-200302180-00014Test; Manara R, Carlier RY, Righetto S, Citton V, Locatelli G, Colas F, et al. Basilar Artery Changes in Fabry Disease. AJNR Am J Neuroradiol. 2017;38(3):531–536. PMID: 28126747 https://doi.org/10.3174/ajnr.A5069Test.; Moore DF, Ye F, Schiffmann R, Butman JA. Increased signal intensity in the pulvinar on T1weighted images: a pathognomonic MR imaging sign of Fabry disease. AJNR Am J Neuroradiol. 2003;24(6):1096–1101. PMID: 12812932; Rolfs A, Böttcher T, Zschiesche M, Morris P, Winchester B, Bauer P, et al. Prevalence of Fabry disease in patients with cryptogenic stroke: a prospective study. Lancet. 2005;366(9499):1794–1796. PMID: 16298216 https://doi.org/10.1016/S0140-6736Test(05)67635-0; Sims K, Politei J, Banikazemi M, Lee P. Stroke in Fabry Disease Frequently Occurs Before Diagnosis and in the Absence of Other Clinical Events Natural History Data From the Fabry Registry. Stroke. 2009;40(3):788– 794. PMID: 19150871 https://doi.org/10.1161/STROKEAHA.108.526293Test; Grisold W, Oberndorfer S, Struhal W. Stroke and cancer: a review. Acta Neurol Scand. 2009;119(1):1–16. PMID: 18616624 https://doi.org/10.1111/j.1600-0404.2008.01059.xTest; Graus F, Rogers LR, Posner JB. Cerebrovascular complications in patients with cancer. Medicine (Baltimore). 1985;64(1):16–35. PMID: 3965856; Kim SJ, Park JH, Lee MJ, Park YG, Ahn MJ, Bang OY. Clues to occult cancer in patients with ischemic stroke. PLoS One. 2012;7(9):e44959. PMID: 22984594 https://doi.org/10.1371/journal.pone.0044959Test; Schwarzbach CJ, Schaefer A, Ebert A, Held V, Bolognese M, Kablau M, et al. Stroke and cancer: the importance of cancer-associated hypercoagulation as a possible stroke etiology. Stroke. 2012;43(11):3029–3034. PMID: 22996958 https://doi.org/10.1161/STROKEAHA.112.658625Test; Kim SG, Hong JM, Kim HY, Held V, Bolognese M, Kablau M, et al. Ischemic stroke in cancer patients with and without conventional mechanisms: a multicenter study in Korea. Stroke. 2010;41(4):798–801. PMID: 20150545 https://doi.org/10.1161/STROKEAHA.109.571356Test; Rogers LR. Cerebrovascular complications in cancer patients. Neurol Clin. 2003;21(1):167–192. PMID: 12690649; Steiner I. Nonbacterial thrombotic endocarditis – a study of 171 case reports. Cesk Patol. 1993;29(2):58–60. PMID: 8339326; Ojeda VJ, Frost F, Mastaglia FL. Non-bacterial thrombotic endocarditis associated with malignant disease: a clinicopathological study of 16 cases. Med J Aust. 1985;142(12):629–631. PMID: 4000038; https://www.jnmp.ru/jour/article/view/691Test

الإتاحة: https://doi.org/10.23934/2223-9022-2019-8-3-302-314Test
https://doi.org/10.23934/2223-9022-2019-8-3Test
https://doi.org/10.1161/01.str.24.1.35Test
https://doi.org/10.3109/07853890.2015.1057612Test
https://doi.org/10.1016/S1474-4422Test(15)00132-5
https://doi.org/10.1161/STROKEAHA.108.529883Test
https://doi.org/10.1161/01.str.19.5.547Test
https://doi.org/10.1161/01.str.15.4.740Test
https://doi.org/10.1161/STROKEAHA.116.013378Test
https://doi.org/10.1161/STROKEAHA.112.671172Test

المؤلفون: R.G. Hart, M. Sharma, H. Mundl, S.E. Kasner, S.I. Bangdiwala, S.D. Berkowitz, B. Swaminathan, P. Lavados, Y. Wang, A. Davalos, N. Shamalov, R. Mikulik, L. Cunha, A. Lindgren, A. Arauz, W. Lang, A. Czlonkowska, J. Eckstein, R.J. Gagliardi, P. Amarenco, S.F. Ameriso, T. Tatlisumak, R. Veltkamp, G.J. Hankey, D. Toni, D. Bereczki, S. Uchiyama, G. Ntaios, B.-W. Yoon, R. Brouns, M. Endres, K.W. Muir, N. Bornstein, S. Ozturk, M.J. O’Donnell, M.M. De Vries Basson, G. Pare, C. Pater, B. Kirsch, P. Sheridan, G. Peters, J.I. Weitz, W.F. Peacock, A. Shoamanesh, O.R. Benavente, C. Joyner, E. Themeles, S.J. Connolly, for the NAVIGATE ESUS Investigators

المساهمون: 손성일, Sohn, Sung Il, Dept. of Neurology (신경과학)

العلاقة: New England Journal of Medicine, Vol.378(23) : 2191-2201, 2018; oak-2018-0969; http://kumel.medlib.dsmc.or.kr/handle/2015.oak/41451Test

الإتاحة: https://doi.org/10.1056/NEJMoa1802686Test
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/41451Test

المؤلفون: S. Boytsov A., S. Martsevich Yu., N. Kutishenko P., M. Loukianov M., A. Mitichkin E., R. Viskov V., L. Stakhovskaya V., N. Shamalov A., G. Arutyunov P., I. Kokareva V., N. Parsadanyan E., M. Chernyshova I., A. Zagrebelnyy V., N. Dmitrieva A., A. Akimova V., G. Nikitina I., O. Lerman V., V. Voronina P., E. Belova N., E. Kudryashov N., A. Deev D., С. Бойцов А., С. Марцевич Ю., Н. Кутишенко П., М. Лукьянов М., А. Митичкин Е., Р. Висков В., Л. Стаховская В., Н. Шамалов А., Г. Арутюнов П., И. Кокарева В., Н. Парсаданян Э., М. Чернышова И., А. Загребельный В., Н. Дмитриева А., А. Акимова В., Г. Никитина И., О. Лерман В., В. Воронина П., Е. Белова Н., Е. Кудряшов Н., А. Деев Д.

المصدر: Rational Pharmacotherapy in Cardiology; Vol 12, No 6 (2016); 645-653 ; Рациональная Фармакотерапия в Кардиологии; Vol 12, No 6 (2016); 645-653 ; 2225-3653 ; 1819-6446 ; 10.20996/1819-6446-2016-12-6

مصطلحات موضوعية: acute cerebrovascular accident, stroke, transient ischemic attack, hospital register, treatment fidelity assessment, острое нарушение мозгового кровообращения, мозговой инсульт, транзиторная ишемическая атака, госпитальный регистр, оценка соответствия терапии клиническим рекомендациям

وصف الملف: application/pdf

العلاقة: https://www.rpcardio.com/jour/article/view/1365/1398Test; Writing Group Members, Mozaffarian D., Benjamin E.J., Go A.S. et al. Heart Disease and Stroke Statistics-2016 Update:AReport From theAmericanHeartAssociation. Circulation. 2016;133(4):e38-e360.; Demographic Yearbook of Russia 2015. Statistical Yearbook. Moscow: Rosstat; 2015. (In Russ.) [Демографический ежегодник России 2015. Статистический сборник. Москва: Росстат; 2015].; Meschia J.F., Bushnell C., Boden-Albala B., et al. Guidelines forthe primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014;45(12):3754-832.; Kernan W.N., Ovbiagele B., Black H.R., et al. Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack. Stroke. 2014;45(7):2160-236.; Saposnik G., Fonarow G.C., Pan W., et al. Guideline-Directed Low-Density Lipoprotein Management in High-Risk Patients With Ischemic Stroke. Stroke. 2014;45(11):3343-51.; Yusuf S., Islam S., Chow C.K., et al. Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey. Lancet. 2011;378(9798):1231-43.; Chow C.K., Teo K.K., Rangarajan S., et al. Prevalence, awareness, treatment, and control of hypertension in rural and urban communities in high-, middle-, and low-income countries. JAMA. 2013;310(9):959-68.; Yusuf S., Rangarajan S., Teo K., и др. Cardiovascular risk and events in 17 low-, middle-, and high-income countries. N Engl J Med. 2014;371(9):818-27.; Howard G., Banach M., Cushman M., et al. Is Blood Pressure Control for Stroke Prevention the Correct Goal? Stroke. 2015;46(6):1595-600.; Boytsov S.A., Martsevich S.Y., Ginzburg M.L., et al. Lyubertsy study on mortality rate in patients after cerebral stroke or transient ischemic attack (LIS-2). Design and medical treatment estimation. Rational Pharmacotherapy in Cardiology. 2013;9(2):114-22. (In Russ.) [Бойцов С.А., Марцевич С.Ю., Гинзбург М.Л., и др. Люберецкое исследование смертности больных, перенесших мозговой инсульт или транзиторную ишемическую атаку (ЛИС-2).Дизайн и оценка лекарственной терапии. Рациональная Фармакотерапия в Кардиологии. 2013;9(2):114-22].; SuvorovA.Y., Martsevich S.Y., Kutishenko N.P., et al. Evaluation of the conformity of cardiovasculartherapy to current clinical guidelines in the improvement of outcomes in patients after stroke (according to the LIS-2 register). Rational Pharmacotherapy in Cardiology. 2015;11(3):247-52. (In Russ.) [Суворов А.Ю., Марцевич С.Ю., Кутишенко Н.П., и др. Оценка соответствия современным клиническим рекомендациям сердечно-сосудистой терапии, направленной на улучшение исходов у пациентов после перенесенного инсульта (по данным регистраЛИС-2). Рациональная Фармакотерапия в Кардиологии. 2015;11(3):247-52].; Suvorov A.Yu., Martsevich S.Yu., Kutishenko N.P. Assessment of quality of care in the registers of acute stroke. Foreign experience, Russia's prospects. Kardiovaskulyarnaya Terapiya i Profilaktika. 2014;13(4):81-6. (In Russ.) [Суворов А.Ю., Марцевич С.Ю., Кутишенко Н.П. Оценка качества терапии в регистрах острого нарушения мозгового кровообращения. Зарубежный опыт, перспективы России. Кардиоваскулярная Терапия и Профилактика. 2014;13(4):81-6].; Klochikhina O.A., Stakhovskaya L.V. Analysis of epidemiological indicators of stroke according to the territorial and population registers 2009-2012. Zhurnal Nevrologii i Psikhiatrii im S.S. Korsakova. 2014;(6):63-9. (In Russ.) [Клочихина О.А., Стаховская Л.В. Анализ эпидемиологических показателей инсульта по данным территориально-популяционных регистров 2009—2012 гг. Журнал Неврологии и Психиатрии им С.С. Корсакова. 2014;(6):63-9].; Saldina I.Y., Klochikhina O.A., Shprakh V.V., Stakhovskaya L.V. Epidemiology of stroke in Irkutsk according to the territorial and population register. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2015;115(9-2):15-9. (In Russ.) [Салдина И.Ю., Клочихина О.А., Шпрах В.В., Стаховская Л.В. Эпидемиология инсульта в Иркутске по данным территориально-популяционного регистра. Журнал Неврологии и Психиатрии им. С.С. Корсакова. 2015;115(9-2):15-9].; Bidenko M.A., Shprakh V.V., Martynenko E.A. The structure, outcomes and risk factors of cerebral stroke according to the hospital register in Irkutsk. Sibirskiy Meditsinskiy Zhurnal. 2008;4:61-4. (In Russ.) [Биденко М.А., Шпрах В.В., Мартыненко Е.А. Структура, исходы и факторы риска мозговых инсультов по данным госпитального регистра в г. Иркутске. Сибирский Медицинский Журнал. 2008;4:61-4].; Spirin N.N., Korneeva N.N. The data of hospital stroke in Kostroma. Fundamental'nye Issledovaniya. 2012;4:123-8. (In Russ.) [СпиринН.Н., КорнееваН.Н.Данные госпитального инсульта в Костроме. Фундаментальные Исследования. 2012;4:123-8].; Boytsov S.A., Martsevich S.Yu., Kutishenko N.P., et al. The registers in cardiology. The basic rules of conduct and a real opportunity. Kardiovaskulyarnaya Terapiya i Profilaktika. 2013;12(1):4-9. (In Russ.) [Бойцов С.А., Марцевич С.Ю., Кутишенко Н.П., и др. Регистры в кардиологии. Основные правила проведения и реальные возможности. Кардиоваскулярная Терапия и Профилактика. 2013;12(1):4-9].; Martsevich S.Y., Kutishenko N.P., Suvorov A.Y., et al. Characteristics of patients with cerebral stroke or transient ischemic attack, included into the lis-2 register (Lyubertsy study of mortality in patients after stroke). Rational Pharmacotherapy in Cardiology. 2015;11(1):18-24. (In Russ.) [Марцевич С.Ю., КутишенкоН.П., СуворовА.Ю., и др. Характеристика пациентов с мозговым инсультом или транзиторной ишемической атакой, включенных в регистрЛИС-2 (Люберецкое исследование смертности больных, перенесших мозговой инсульт). Рациональная Фармакотерапия в Кардиологии. 2015;11(1):18-24].; Martsevich S.Y., Kutishenko N.P., SuvorovA.V., et al. The main factors affecting the long-term outcomes in patients after acute cerebrovascular disorder: results of the LIS-2 study. Rational Pharmacotherapy in Cardiology. 2016;12(1):51-5. (In Russ.) [Марцевич С.Ю., Кутишенко Н.П., Суворов А.Ю., и др. Основные факторы, влияющие на отдаленные исходызаболевания у больных, перенесших острое нарушение мозгового кровообращения: результаты исследования ЛИС-2. Рациональная Фармакотерапия в Кардиологии. 2016;12(1):51-5].; Martsevich S.Yu., Kutishenko N.P., Suvorov A.Yu., et al. Analysis of anamnestic factors and their role in determining the nearest (hospital) prognosis in patients after stroke or transient ischemic attack. register LIS-2 results. Rossiyskiy Kardiologicheskiy Zhurnal. 2015;122(6):14-9. (In Russ.) [Марцевич С.Ю., Кутишенко Н.П., Суворов А.Ю., и др. Анализ анамнестических факторов и их роль в определении ближайшего (госпитального) прогноза у больных, перенесших мозговой инсульт или транзиторную ишемическую атаку. Результаты регистра ЛИС-2. Российский Кардиологический Журнал. 2015;122(6):14-9].; https://www.rpcardio.com/jour/article/view/1365Test

الإتاحة: https://doi.org/10.20996/1819-6446-2016-12-6-645-653Test
https://doi.org/10.20996/1819-6446-2016-12-6Test
https://www.rpcardio.com/jour/article/view/1365Test

المؤلفون: M. Kustova A., A. Tolmachev P., N. Shamalov A., М. Кустова А., А. Толмачев П., Н. Шамалов А.

المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 8, No 2 (2016); 80-86 ; Неврология, нейропсихиатрия, психосоматика; Vol 8, No 2 (2016); 80-86 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2016-2

مصطلحات موضوعية: ischemic stroke, rehabilitation, neuroprotectors, cerebrolysin, CARS study, ишемический инсульт, реабилитация, нейропротекторы, церебролизин, исследование CARS

وصف الملف: application/pdf

العلاقة: https://nnp.ima-press.net/nnp/article/view/613/563Test; Murray CJ, Lopez AD. Measuring the global burden of disease. N Engl J Med. 2013 Aug 1;369(5):448-57. doi:10.1056/NEJMra1201534.; Powers WJ, Derdeyn CP, Biller J, et al., on behalf of the American Heart Association Stroke Council. 2015 AHA/ASA Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment. A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke. 2015; 46:3020-3035. Stroke. 2015;46:3020-3035 Published online before print June 29, 2015, doi:10.1161/ STR.0000000000000074; Saver JL, Smith EE, Fonarow GC, et al. GWTG- Stroke Steering Committee and Investigators. The «golden hour» and acute brain ischemia: presenting features and lytic therapy in >30,000 patients arriving within 60 minutes of stroke onset. Stroke. 2010 Jul;41(7):1431-9. doi:10.1161/ STROKEAHA.110.583815. Epub 2010 Jun 3.; Zahuranec DB, Majersik JJ. Percentage of acute stroke patients eligible for endovascular treatment. Neurology. 2012 Sep 25;79(13 Suppl 1):S22-5.; Шамалов НА. Проблемы и перспективы реперфузионной терапии при ишемическом инсульте в России. Фарматека. 2015;302(9):14-9. [Shamalov NA. Problems and prospects of reperfusion therapy in ischemic stroke in Russia. Farmateka. 2015;302(9):14-9. (In Russ.)].; O’Collins VE, Macleod MR, Donnan GA, et al. 1,026 experimental treatments in acute stroke. Ann Neurol. 2006 Mar;59(3):467-77. doi:10.1002/ana.20741; Kaur H, Prakash A, Medhi B. Drug therapy in stroke: from preclinical to clinical studies. Pharmacology. 2013;92(5-6):324-34. doi:10.1159/000356320. Epub 2013 Dec 12.; Xu SY, Pan SY. The failure of animal models of neuroprotection in acute ischemic stroke to translate to clinical efficacy. Med Sci Monit Basic Res. 2013 Jan 28;19:37-45.; Tymianski M. Novel approaches to neuroprotection trials in acute ischemic stroke. Stroke. 2013 Oct;44(10):2942-50. doi:10.1161/ STROKEAHA.113.000731. Epub 2013 Sep 10.; Hossmann KA. The two pathophysiologies of focal brain ischemia: implications for translational stroke research. J Cereb Blood Flow Metab. 2012 Jul;32(7):1310-6. doi:10.1038/jcbfm.2011.186. Epub 2012 Jan 11.; Masliah E, Diez-Tejedor E. The pharmacology of neurotrophic treatment with Cerebrolysin: brain protection and repair to counteract pathologies of acute and chronic neurological disorders. Drugs Today (Barc). 2012 Apr;48 Suppl A:3-24. doi:10.1358/ dot.2012.48(Suppl.A).1739716.; Hartbauer M, Hutter-Paier B, Skofitsch G, Windisch M. Antiapoptotic effects of the peptidergic drug cerebrolysin on primary cultures of embryonic chick cortical neurons. J Neural Transm (Vienna). 2001;108(4):459-73.; Zhang L, Chopp M, Meier DH, et al. Sonic hedgehog signaling pathway mediates cerebrolysin-improved neurological function after stroke. Stroke. 2013 Jul;44(7):1965-72. doi:10.1161/STROKEAHA.111.000831. Epub 2013 May 21.; Gutmann B, Hutter-Paier B, Skofitsch G, et al. In vitro models of brain ischemia: the peptidergic drug cerebrolysin protects cultured chick cortical neurons from cell death. Neurotox Res. 2002 Feb;4(1):59-65. doi:10.1080/ 10298420290007637.; Darsalia V, Heldmann U, Lindvall O, Kokaia Z. Stroke-induced neurogenesis in aged brain. Stroke. 2005 Aug;36(8):1790-5. Epub 2005 Jul 7. doi:10.1161/01. STR.0000173151.36031.be.; Скворцова ВИ, Стаховская ЛВ, Губский ЛВ и др. Рандомизированное двойное слепое плацебоконтролируемое иссле- дование безопасности и эффективности церебролизина для лечения острого ишемиче- ского инсульта. Журнал неврологии и психиатрии им. С.С. Корсакова (Прил. Инсульт). 2004;(S11):51-5. [Skvortsova VI, Stakhovskaya LV, Gubskii LV, et al. A randomized, double-blind, placebocontrolled trial of safety and efficacy of Cerebrolysin for treating acute ischaemic stroke. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova (Suppl. Stroke). 2004;(S11):51-5. (In Russ.)].; Ladurner G, Kalvach P, Moessler H; Cerebrolysin Study Group. Neuroprotective treatment with cerebrolysin in patients with acute stroke: a randomised controlled trial. J Neural Transm (Vienna). 2005 Mar;112(3):415-28. Epub 2004 Dec 7. doi:10.1007/s00702-004-0248-2.; Ziganshina LE, Abakumova T, Kuchaeva A. Cerebrolysin for acute ischaemic stroke. Cochrane Database Syst Rev. 2010 Apr 14;(4): CD007026. doi:10.1002/14651858. CD007026.pub2.; Lang W, Stadler CH, Poljakovic Z, Fleet D; Lyse Study Group. A prospective, randomized, placebo-controlled, double-blind trial about safety and efficacy of combined treatment with alteplase (rt-PA) and Cerebrolysin in acute ischaemic hemispheric stroke. Int J Stroke. 2013 Feb;8(2):95-104. doi:10.1111/j.1747- 4949.2012.00901.x. Epub 2012 Sep 26.; Heiss WD, Brainin M, Bornstein NM, et al; Cerebrolysin Acute Stroke Treatment in Asia (CASTA) Investigators. Cerebrolysin in patients with acute ischemic stroke in Asia: results of a double-blind, placebo-controlled randomized trial. Stroke. 2012 Mar;43(3):630-6. doi:10.1161/STROKEAHA.111.628537. Epub 2012 Jan 26.; Muresanu DF, Heiss WD, Hoemberg V, et al. Cerebrolysin and Recovery After Stroke (CARS). A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial. Stroke. 2016 Jan;47(1):151-9. doi:10.1161/STROKEAHA.115.009416. Epub 2015 Nov 12.; Lyle RC. A performance test for assessment of upper limb function in physical rehabilitation treatment and research. Int J Rehabil Res. 1981;4(4):483-92. doi:10.1097/ 00004356-198112000-00001.; Posteraro L, Formis A, Grassi E, et al. Quality of life and aphasia. Multicentric standardization of a questionnaire. Eura Medicophys. 2006 Sep;42(3):227-30.; Goodglass H, Kaplan E. The Assessment of Aphasia and Related Disorders. 2nd ed. Philadelphia, PA: Lea & Febiger; 1983.; https://nnp.ima-press.net/nnp/article/view/613Test

الإتاحة: https://doi.org/10.14412/2074-2711-2016-2-80-86Test
https://doi.org/10.14412/2074-2711-2016-2Test
https://doi.org/10.1056/NEJMra1201534Test
https://doi.org/10.1002/ana.20741Test
https://doi.org/10.1159/000356320Test
https://doi.org/10.1038/jcbfm.2011.186Test
https://doi.org/10.1161/STROKEAHA.111.000831Test
https://doi.org/10.1161/01Test
https://doi.org/10.1007/s00702-004-0248-2Test
https://doi.org/10.1002/14651858Test

المؤلفون: N. Shamalov A., K. Anisimov V., M. Kustova A., A. Tolmachev P., Н. Шамалов А., К. Анисимов В., М. Кустова А., А. Толмачев П.

المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 6, No 3 (2014); 61-68 ; Неврология, нейропсихиатрия, психосоматика; Vol 6, No 3 (2014); 61-68 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2014-3

مصطلحات موضوعية: ischemic stroke, thrombolytic therapy, ишемический инсульт, тромболитическая терапия

وصف الملف: application/pdf

العلاقة: https://nnp.ima-press.net/nnp/article/view/439/428Test; Available from: http://www.eso-stroke.orgTest; Jauch EC, Saver JL, Adams HP Jr, et al.; American Heart Association Stroke Council; Council on Cardiovascular Nursing; Council on Peripheral Vascular Disease; Council on Clinical Cardiology. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013;44:870–947. DOI: http://dx.doi.org/10.1161/STR.0b013e318284056aTest.; Tillet WS, Garner RL. The fibrinolytic activity of hemolytic streptococci. J Exp Med. 1933;58:485–520. DOI: http://dx.doi.org/10.1084/jem.58.4.485Test.; Fletcher AP, Alkjaersig N, Smyrniotis FE, Sherry S. The treatment of patients suffering from early myocardial infarction with massive and prolonged streptokinase therapy. Trans Assoc Am Phys. 1958;71:287–96.; Del Zoppo GJ, Zeumer H, Harker LA. Thrombolytic therapy in acute stroke: Possibilities and hazards. Stroke. 1986;17:595–607. DOI: http://dx.doi.org/10.1161/01.STR.17.4.595Test.; Ringelstein EB, Zeumer H. The role of continuous-wave Doppler sonography in the diagnosis and management of basilar and vertebral artery occlusions, with special reference to its application during local fibrinolysis. J Neurol. 1982;228:161–70. DOI: http://dx.doi.org/10.1007/BF00313728Test.; Zeumer H, Hacke W, Ringelstein EB. Local intraarterial thrombolysis in vertebrobasilar thromboembolic disease. Am J Neuroradiol. 1983;4(3):401–4.; Solis OJ, Roberson GR, Taveras JM, et al. Cerebral angiography in acute cerebral infarction. Rev Interam Radiol. 1977;2(1):19–25.; Matsuo O, Kosugi T, Mihara H, et al. Retrospective study on the efficacy of using urokinase therapy. Acta Haem Jap. 1979;42:684–8.; Multicentre Acute Stroke Trial – Italy (Mast-I) Group. Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischaemic stroke. Lancet. 1995 Dec 9;346(8989):1509–14. DOI: http://dx.doi.org/10.1016/S0140Test- 6736(95)92049-8.; Multicentre Acute Stroke Trial – Europe tudy Group. Thrombolytic therapy with streptokinase in acute ischemic stroke. N Engl J Med. 1996 Jul 18;335(3):145–50. DOI: http://dx.doi.org/10.1056/NEJM199607183350301Test.; Yasaka M, Chambers BR, Davis SM, Donnan GA. Streptokinase in acute stroke: effect on reperfusion and recanalization. Australian Streptokinase Trial Study Group. Neurology. 1998 Mar;50(3):626–32. DOI: http://dx.doi.org/10.1212/WNL.50.3.626Test.; Seifried E, Tanswell P, Ellbrü ck D, et al. Pharmacokinetics and haemostatic status during consecutive infusions of recombinant tissuetype plasminogen activator in patients with acute myocardial infarction. Thromb Haemostas. 1989;61(3):497–501.; Tanswell P, Tebbe U, Neuhaus K-L, et al. Pharmacokinetics and fibrin specificity of Alteplase during accelerated infusions in acute myocardial infarction. J Am Coll Cardiol. 1992;19:1071–5. DOI: http://dx.doi.org/10.1016/0735-1097Test(92)90297-Z.; Brott TG, Haley EC Jr, Levy DE, et al. Urgent therapy for stroke. Part I. Pilot study of tissue plasminogen activator administered within 90 minutes. Stroke. 1992;23:632–40. DOI: http://dx.doi.org/10.1161/01.STR.23.5.632Test.; Haley EC Jr, Levy DE, Brott TG, et al. Urgent therapy for stroke. Part II. Pilot study of tissue plasminogen activator administered 91–180 minutes from onset. Stroke. 1992;23:641–5. DOI: http://dx.doi.org/10.1161/01.STR.23.5.641Test.; Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. New Engl J Med. 1995;333(24):1581–7.; Hacke W, Kaste M, Fieschi C, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke the european cooperative acute stroke study (ECASS). JAMA. 1995;274(13):1017–25.; Hacke W, Kaste M, Fieschi C, et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet. 1998;352(9136):1245–51.DOI: http://dx.doi.org/10.1016/S0140-6736Test(98)08020-9.; Clark WM, Wissman S, Albers GW, et al. Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. JAMA. 1999;282:2019–26. DOI: http://dx.doi.orgTest/ 10.1001/jama.282.21.2019.; Hacke W, Kaste M, Bluhmki E, et al.; ECASS Investigators. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359:1317–29. DOI:10.1056/NEJMoa0804656.; Sandercock P, Wardlaw JM, Lindley RI, et al.; IST-3 collaborative group. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet. 2012;379(9834):2352–63. DOI: http://dx.doi.org/10.1016/S0140Test- 6736(12)60768-5.; Indyk JA, Chen ZL, Tsirka SE, Strickland S. Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury. Neuroscience. 2003;116:359–71. DOI: http://dx.doi.org/10.1016/S0306-4522Test(02)00704-2.; Lo EH, Broderick JP, Moscowitz MA. tPA and proteolysis in the neurovascular unit. Stroke. 2004;35(2):354–6. DOI: http://dx.doi.org/10.1161/01.STR.0000115164.80010.8ATest.; Furlan AJ, Eyding D, Albers GW, et al.; DEDAS Investigators. Dose escalation of desmoteplase for acute ischemic stroke (dedas): evidence of safety and efficacy 3 to 9 hours after stroke onset. Stroke. 2006;37:1227–31. DOI: http://dx.doi.org/10.1161Test/ 01.STR.0000217403.66996.6d.; Hacke W, Albers G, Al-Rawi Y., et al. The Desmoteplase in Acute Ischemic Stroke Trial (DIAS). A phase II MRI – based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke. 2005;36:66–73. DOI: http://dx.doi.org/10.1161/01.STRTest. 0000149938.08731.2c.; Hacke W, Furlan AJ, Al-Rawi Y, et al. Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusiondiffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, doubleblind, placebo-controlled study. Lancet Neurol. 2009;8(2):141–50. DOI: http://dx.doi.org/10.1016/S1474-4422Test(08)70267-9.; Kratzschmar J, Haendler B, Langer G, et al. The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression. Gene. 1991;105:229–37. DOI: http://dx.doi.org/10.1016/0378-1119Test(91)90155-5.; Lopez-Atalaya JP, Roussel BD, Ali C, et al. Recombinant desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptorrelated protein-dependent mechanism without exerting neurotoxic effects. Stroke. 2007;38:1036–43. DOI: http://dx.doi.org/10.1161/01Test. STR.0000258100.04923.84.; Hacke W, Donnan G, Fieschi C, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004;363:768–74. DOI: http://dx.doi.org/10.1016/S0140-6736Test(04)15692-4.; Bray BD, Campbell J, Cloud GC, et al.; Intercollegiate Stroke Working Party Group. Bigger, Faster? Associations between hospital thrombolysis volume and speed of thrombolysis administration in acute ischemic stroke. Stroke. 2013;44:3129–35. DOI: http://dx.doi.org/10.1161Test/ STROKEAHA.113.001981.; Carlson MD, Leber S, Deveikis J, Silverstein FS. Successful use of rt-PA in pediatric stroke. Neurology. 2001;57:157–8. DOI: http://dx.doi.org/10.1212/WNL.57.1.157Test.; Engelter ST, Bonati LH, Lyrer PA. Intravenous thrombolysis in stroke patients of 80 versus 80 years of age – a systematic review across cohort studies. Age Ageing. 2006;35:572–80. DOI: http://dx.doi.org/10.1093/ageing/afl104Test.; Mateen FJ, Buchan AM, Hill MD; CASES Investigators. Outcomes of thrombolysis for acute ischemic stroke in octogenarians versus nonagenarians. Stroke. 2010;41:1833–5. DOI: http://dx.doi.org/10.1161/STROKEAHATest. 110.586438.; Khaw KT, Barrett-Connor E, Suarez L, Criqui MH. Predictors of stroke associated mortality in the elderly. Stroke. 1984;15:244–8. DOI: http://dx.doi.org/10.1161Test/ 01.STR.15.2.244.; Wardlaw JM, Murray V, Berge E, Del Zoppo GJ. Thrombolysis for acute ischemic stroke. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD000213. DOI:10.1002/14651858.CD000213.pub2.; Anzini A, Niaz A, Durastanti L, et al. Thrombolysis in young patients: the SITSMOST data. Cerebrovasc Dis. 2008;25 (Suppl 2):3.; Putaala J, Metso TM, Metso AJ, et al. Thrombolysis in young adults with ischemic stroke. Stroke. 2009;40:2085–91. DOI: http://dx.doi.org/10.1161Test/ STROKEAHA.108.541185.; Holroyd-Leduc JM, Kapral MK, Austin PC, Tu JV. Sex differences and similarities in the management and outcome of stroke. Stroke. 2000;31:1833–7. DOI: http://dx.doi.org/10.1161/01.STR.31.8.1833Test.; Kapral MK, Fang J, Hill MD, et al.; Investigators of the Registry of the Canadian Stroke Network. Sex differences in stroke care and outcomes: results from the registry of the canadian stroke network. Stroke. 2005;36:809–14. DOI: http://dx.doi.org/10.1161/01.STRTest. 0000157662.09551.e5.; Meseguer E, Mazighi M, Labreuche J, et al. Outcomes of intravenous recombinant tissue plasminogen activator therapy according to gender: a clinical registry study and systematic review. Stroke. 2009;40:2104–10. DOI: http://dx.doi.org/10.1161/STROKEAHATest. 108.546325.; Savitz SI1, Schlaug G, Caplan L, Selim M. Arterial occlusive lesions recanalize more frequently in women than in men after intravenous tissue plasminogen activator administration for acute stroke. Stroke. 2005;36:1447–51. DOI: http://dx.doi.org/10.1161/01.STRTest. 0000170647.42126.a8.; Kent DM, Price LL, Ringleb P, et al. Sex-based differences in response to recombinant tissue plasminogen activator in acute ischemic stroke: a pooled analysis of randomized clinical trials. Stroke. 2005;36:62–5. DOI: http://dx.doi.org/10.1161/01.STRTest. 0000150515.15576.29.; Fö rster A, Gass A, Kern R, et al. Gender differences in acute ischemic stroke: etiology, stroke patterns and response to thrombolysis. Stroke. 2009;40:2428–32. DOI: http://dx.doi.org/10.1161/STROKEAHA.109.548750Test.; Tafreshi GM, Raman R, Ernstrom K, et al. Gender differences in acute stroke treatment: the University of California San Diego experience. Stroke. 2010;41:1755–7. DOI: http://dx.doi.org/10.1161/STROKEAHATest. 110.584136.; Pessin M, del Zoppo GJ, Estol C. Thtombolytic agents in the treatment of stroke. Clin Neuropharmacol. 1990;13:271–89. DOI: http://dx.doi.org/10.1097/00002826Test- 199008000-00001.; Okada Y, Yamaguchi T, Minematsu K, et al. Hemorrhagic transformation in cerebral embolism. Stroke. 1989;20:598–603. DOI: http://dx.doi.org/10.1161/01.STR.20.5.598Test.; Lodder J, Krijne-Kubat B, Broekman J. Cerebral hemorrhagic infarction at autopsy: cardiac embolic cause and the relationship to the cause of death. Stroke. 1986;17:626–9. DOI: http://dx.doi.org/10.1161/01.STR.17.4.626Test.; Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke. 1997;28:2119–25. DOI: http://dx.doi.org/10.1161/01.STR.28.11.2119Test.; Fiorelly M, Bastianello S, von Kummer R, et al.; ECASS I Study Group. Hemorrhagic transformation within 36 hours of a cerebral infarct. Relationship with early clinical deterioration and 3-month outcome in the ECASS I cohort. Stroke. 1999;30:2280–4. DOI: http://dx.doi.org/10.1161/01.STR.30.11.2280Test.; Molina CA, Alvarez-Sabin J, Montaner J, et al. Thrombolysis-related hemorragic infarction: a marker of early reperfusion, reduced infarct size, and improved outcome in patients with proximal middle cerebral artery occlusion. Stroke. 2002;33;1551–6. DOI: http://dx.doi.org/10.1161/01Test. STR.0000016323.13456.E5.; Neumann-Haefelin T, Hoelig S, Berkefeld J, et al. Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute Stroke. Stroke. 2006;37:2463–6. DOI: http://dx.doi.org/10.1161/01.STR.0000239321.53203.eaTest.; Dubey N, Bakshi R, Wasay M, Dmochowski J. Early computed tomography hypodensity predicts hemorrhage after intravenous tissue plasminogen activator in acute ischemic stroke. J Neuroimaging. 2001;11:184–8. DOI: http://dx.doi.org/10.1111/j.1552Test- 6569.2001.tb00031.x.; Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group. Stroke. 1997;28:2109–18. DOI: http://dx.doi.org/10.1161/01.STR.28Test. 11.2109.; Barber PA, Demchuk AM, Zhang J, Buchan AM. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet. 2000;355:1670–4. DOI: http://dx.doi.org/10.1016/S0140Test- 6736(00)02237-6.; Dzialowski I, Hill MD, Coutts SB, et al. Extent of early ischemic changes on computed tomography (ct) before thrombolysis: prognostic value of the Alberta Stroke Program Eearly CT Score in ECASS II. Stroke. 2006;37:973–8. DOI: http://dx.doi.org/10.1161/01Test. STR.0000206215.62441.56.; Lindsberg PJ, Hä ppö lä O, Kallela M, et al. Door to thrombolysis: ER reorganization and reduced delays to acute stroke treatment. Neurology. 2006;67:334–6. DOI: http://dx.doi.org/10.1212/01.wnlTest. 0000224759.44743.7d.; Martin-Schild S, Morales MM, Khaja AM, et al. Is the drip-and-ship approach to delivering thrombolysis for acute ischemic stroke safe? J Emerg Med. 2011 Aug;41(2):135–41. DOI:10.1016/j.jemermed.2008.10.018. Epub 2009 Mar 9; Mayer TE, Hamann GF, Brueckmann HJ. Treatment of basilar artery embolism with a mechanical extraction device: necessity of flow reversal. Stroke. 2002;33:2232–5. DOI: http://dx.doi.org/10.1161/01.STRTest. 0000024524.71680.C6.; Hacke W, Zeumer H, Ferbert A, et al. Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. Stroke. 1988;19:1216–22. DOI: http://dx.doi.org/10.1161/01Test. STR.19.10.1216.; Brandt T, von Kummer R, Muller-Kuppers M, Hacke W. Thrombolytic therapy of acute basilar artery occlusion. Variables affecting recanalization and outcome. Stroke. 1996;27:875–81. DOI: http://dx.doi.org/10.1161/01Test. STR.27.5.875.; Schonewille WJ, Wijman CA, Michel P, et al. Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study. Lancet Neurol. 2009;8:724–30. DOI: http://dx.doi.org/10.1016/S1474Test- 4422(09)70173-5.; Martin-Schild S, Morales MM, Khaja AM, et al. Is the drip-and-ship approach to delivering thrombolysis for acute ischemic stroke safe? J Emerg Med. 2009.; Silverman IE, Beland DK, Chhabra J, McCullough LD. The «Drip-and-ship» approach: starting IV t-Pa for acute ischemic stroke at outside hospitals prior to transfer to a regional stroke center. Conn Med. 2005;69:613–20.; Pfefferkorn T, Mayer TE, Opherk C, et al. Staged escalation therapy in acute basilar artery occlusion: Intravenous thrombolysis and ondemand consecutive endovascular mechanical thrombectomy: Preliminary experience in 16 patients. Stroke. 2008;39:1496–500. DOI: http://dx.doi.org/10.1161/STROKEAHATest. 107.505123.; Pfefferkorn T, Holtmannspotter M, Schmidt C, et al. Drip, ship, and retrieve: cooperative recanalization therapy in acute basilar artery occlusion. Stroke. 2010;41:722–6. DOI: http://dx.doi.org/10.1161/STROKEAHATest. 109.567552.; https://nnp.ima-press.net/nnp/article/view/439Test

الإتاحة: https://doi.org/10.14412/2074-2711-2014-3-61-68Test
https://doi.org/10.14412/2074-2711-2014-3Test
https://doi.org/10.1161/STR.0b013e318284056aTest
https://doi.org/10.1084/jem.58.4.485Test
https://doi.org/10.1161/01.STR.17.4.595Test
https://doi.org/10.1007/BF00313728Test
https://doi.org/10.1016/S0140Test
https://doi.org/10.1056/NEJM199607183350301Test
https://doi.org/10.1212/WNL.50.3.626Test
https://doi.org/10.1016/0735-1097Test(92)90297-Z

المؤلفون: Scott E Kasner, Balakumar Swaminathan, Pablo Lavados, Mukul Sharma, Keith Muir, Roland Veltkamp, Sebastian F Ameriso, Matthias Endres, Helmi Lutsep, Steven R Messé, J David Spence, Krassen Nedeltechev, Kanjana Perera, Gustavo Santo, Veronica Olavarria, Arne Lindgren, Shrikant Bangdiwala, Ashkan Shoamanesh, Scott D Berkowitz, Hardi Mundl, Stuart J Connolly, Robert G Hart, N Abdelhamid, D Abdul Rahman, M Abdul-Saheb, P Abreu, M Abroskina, F Abu Ahmad, S Accassat, M Acciaresi, A Adami, N Ahmad, F Ahmed, M Alberto Hawkes, F Alemseged, A Ali, R Altavilla, L Alwis, P Amarenco, S Amaro, LE Amaya Sanchez, A Amelia Pinto, SF Ameriso, H Amin, T Amino, AK Amjad, E Anagnostou, G Andersen, C Anderson, DC Anderson, M Andrea Falco, F Andres Mackinnon, D Andreu, M Androulakis, M Angel Gamero, G Angel Saredo, R Angeles Diaz, M Angels Font, S Anticoli, A Arauz, AA Arauz Gongora, P Araya, JF Arenillas Lara, S Arias Rivas, M Arnold, S Augustin, W Avelar, E Azevedo, V Babikian, A Bacellar, K Badalyan, HJ Bae, EM Baez Martinez, H Bagelmann, P Bailey, Z Bak, M Baker, A Balazs, D Baldaranov, I Balogun, T Balueva, Z Bankuti, M Bar, A Baranowska, J Bardutzky, S Barker Trejo, J Barlinn, F Baronnet, C Barroso, M Barteys, T Bartolottiova, A Barulin, M Bas, S Bashir, V Basile, R Bathe-Peters, R Bathula, C Batista, H Batur Caglayan, P Baumgartner, R Bazan, O Bazhenova, M Beaudry, J Beer, Y Behnam, C Beilei, A Beinlich, Y Bejot, A Belkin, OR Benavente, A Benjamin, V Berardi, D Bereczki, SD Berkowitz, J Berlingieri, W Berrios, J Berrouschot, M Bhandari, M Bhargavah, H Bicker, T Bicsak, M Bilik, D Bindila, J Birchenall, L Birnbaum, T Black, D Blacker, D Blacquiere, C Blanc-Labarre, C Blank, B Blazejewska-Hyzorek, S Bloch, E Bodiguel, E Bogdanov, L Boos, L Borcsik, N Bornstein, S Bouly, G Braga, I Bragado, MC Bravi, C Brokalaki, W Brola, R Brouns, D Bruce, J Brzoska-Mizgalska, B Buck, M Buksinska-Lisik, J Burke, M Burn, G Bustamante, L Cabrejo, K Cai, S Cajaraville, M Calejo, D Calvet, J Campillo, E Campos Costa, P Camps, H Can Alaydin, E Candeloro, C Canepa, CG Cantu Brito, M Cappellari, C Carcel, P Cardona Portela, F Cardoso, M Carek, M Carletti, J Carlos Portilla, P Caruso, I Casado-Naranjo, P Castellini, D Castro, F Castro Meira, A Cavallini, N Cayuela Caudevilla, S Cenciarelli, C Cereda, P Cerrone, A Chakrabarti, P Chaloulos-Iakovidis, A Chamorro, D Chandrasena, DI Chang, C Che, J Chembala, J Chen, Z Chen, T Chen, H Chen, X Chen, G Chen, L Chen, S Chen, B Cheripelli, M Chin, E Chiquete Anaya, M Chorazy, H Christensen, T Christensen, L Christian, F Chu, CS Chung, W Clark, R Clarke, S Claverie, E Clemente Agostoni, B Clissold, J Coelho, D Cohen, S Colakoglu, D Collas, R Condurso, SJ Connolly, D Consoli, C Constantin, AB Constantino Silva, L Contardo, A Corlobe, M Correia, C Correia, E Cortijo Garcia, B Coull, S Coutts, S Coveney, P Cras, R Crols, S Crozier, A Csanyi, L Csiba, K Csontos, R Csuha, L Cui, L Cunha, S Curtze, M Czerska, A Czlonkowska, M Czurko, M Czuryszkiewicz, M Dagnino, C Dai, A Daineko, G Dalek, D Damgaard, A Danese, K Dani, V Danku, W Dario Toledo, A Dávalos, A De Havenon, J De Keyser, N De Klippel, J De La Torre, A De Pauw, A De Smedt, R De Torres, MM De Vries Basson, J Dearborn, R Deganutto, M Degeorgia, I Deguchi, A Del Giudice, C Delcourt, R Delgado-Mederos, G Della Marca, B Delpont, S Deltour, DL Demets, M Dennis, J Desai, J Devine, I Dhollander, MT Di Mascio, M Diaconu, F Diaz Otero, J Dietzel, E Diez-Tejedor, N Ding, J Ding, M Diomedi, P Dioszeghy, M Distefano, V Domigo, E Dorodnicov, D Dossi, F Doubal, I Druzenko, P Du, J Du, T Duman, Y Duodu, D Dutta, L Dylewicz, J Eckstein, E Ehrensperger, S Ehrlich, G Einer Allende, B Elena Halac, S Elyas, M Endres, JM Engelbrecht, S Engelter, M Epinat, F Eren, M Esbjornsson, B Escribano, I Escudero, B Esisi, B Essa, M Esterbauer, N Evans, D Eveson, S Fabio, L Fang, S Fanta, M Fares, M Fatar, K Faust, A Favate, F Fazekas, M Federica Denaro, A Fedin, P Felipe Amaya, J Feng, K Ferencova, M Fernanda Gilli, MD Fernandez, PN Fernandez Pirrone, J Fernandez Vera, J Ferrari, A Ferreira, G Ferreira Junior, M Fidler, D Field, T Field, C Figueroa, J Fiksa, A Filipov, A Firstenfeld, L Fisch, U Fischer, M Fisselier, U Fiszer, F Fluri, G Fortea, K Fotherby, A Fraczek, E France, G Freitas, S Frey, M Frick, A Friedman, M Friedrich, G Frisullo, W Fryze, B Fuentes Gimeno, H Fujigasaki, K Fukuyama, A Furlan, G Furlanis, J Furnace, M Gabriel, E Gabriel Reich, RJ Gagliardi, F Galati, E Galli Giqueauk, A Gallina, E Gallinella, J Gallo, S Gangadharan, Y Gao, R Garcia Lopez, A Garcia Pastor, SM Garcia Sanchez, M Garnauf, P Garnier, D Gasecki, K Gasic, K Gasiorek, S Gasser, M Gaugg, M Gebreyohanns, K Gebura, J Geng, M Geniz Clavijo, K Georg Haeusler, R Geran, M Geremek, Z Gerocs, D Ghia, D Giannandrea, F Giatsidis, JA Gien Lopez, A Gil Nunez, L Gimenez, E Giralt, A Glabinski, D Gladstone, M Gliem, M Gluszkiewicz, R Goddeau, E Gogoleva, M Gokce, D Goldemund, K Golikov, A Gomes Neto, M Gomez Schneider, M Gomez-Choco, M Gomis, JF Gongora-Rivera, Y Gonysheva, L Gonzalez, ME Gonzalez Toledo, M Gottschal, I Gozdzik, S Grabowski, S Graf, D Green, D Greer, T Gregorio, S Greisenegger, I Greshnova, M Griebe, M Grzesik, J Guan, S Guarda, A Gueguen, C Guidoux, P Guillermo Povedano, B Guillon, V Guiraudg, G Gunathilagan, N Guryanova, V Gusev, G Gustavo Persi, R Gutiérrez, P Guyler, N Gyuker, V Hachinski, A Hajas, H Hallevi, G Hankey, GJ Hankey, L Hanouskova, L Hao, K Haraguchi, Y Haralur Sreekantaiah, S Haratz, D Hargroves, K Harkness, P Harmel, M Harrasser, RG Hart, M Harvey, R Hasan, Y Hasegawa, A Hassan, M Hattori, A Hatzitolios, M Hauk, T Hayashi, H Hayhoe, VS Hedna, M Heine, V Held, S Hellwig, J Henkner, N Henninger, S Hermans, J Hernandez, D Herrero, M Hervieu-Begue, R Herzig, L Hicken, M Hieber, M Hill, M Hirose, MC Hobeanu, B Hobson, M Hochstetter, J Hoe Heo, M Hoffmann, C Holmstedt, P Hon, KS Hong, Y Honma, A Horev, G Horgan, L Horvath, M Horvath, C Hoyer, D Huang, H Huang, B Huber, J Huhtakangas, M Hussain, S Igarashi, AM Iglesias Mohedano, J Ignacio Tembl, M Impellizzeri, Y Inanc, P Ioli, A Irina Aniculaesei, K Ishida, R Itabashi, H Iversen, A Jagolino, K Jakab, S Jander, H Janka, J Jankovych, J Jansen, L Jasek, M Javier Alet, L Javor, X Jin, P Jing, B Joachim, M Joan Macleod, M Johnson, J Jose Martin, C Joyner, K Judit Szabo, A Jun-Oconnell, R Jura, B Kaczorowska, J Kadlcikova, T Kahles, N Kakaletsis, I Kakuk, K Kalinowska, K Kaminska, C Kaneko, I Kanellos, P Kapeller, K Kapica-Topczewska, O Karasz, M Karlinski, JE Karlsson, K Kasa, E Kashaeva, SE Kasner, M Kaste, J Kasza, A Katalin Iljicsov, M Katsurayama, S Kaur, M Kawanishi, S Kaygorodtseva, K Ke, A Kei, J Keilitz, J Kellner, P Kelly, S Kelly, D Kemlink, M Kerekgyarto, I Keskinarkaus, D Khairutdinova, A Khanna, A Khaw, M Kholopov, C Khoumri, S Kirpicheva, H Kirshner, K Kitagawa, S Kittner, R Kivioja, F Klein, D Kleindorfer, T Kleinig, P Klivenyi, S Knecht, Y Kobayashi, A Kobayashi, M Koch, L Koehler, M Koivu, V Kolianov, I Koltsov, T Kondo, I Konkov, S Kopecky, E Korompoki, J Korpela, K Kosarz-Lanczek, A Koutroubi, K Kovacs, T Kovacs, H Kovacs, K Kowalczyk, M Kowalska, D Krajickova, M Kral, C Krarup Hansen, J Kraska, S Krebs, V Krejci, C Kremer, R Kreuzpointer, M Krzyzanowska, D Kucken, A Kulakowska, J Kunzmann, N Kurenkova, A Kuris, I Kurkowska-Jastrzebska, N Kurtenkova, O Kurushina, G Kusnick, M Kustova, T Kuwashiro, J Kwan Cha, A Lago, M Lagutenko, B Lajos, J Lambeck, C Lamy, A Landolfi, S Lanfranconi, W Lang, LB Lara Lezama, B Lara Rodriguez, T Largo, A Lasek-Bal, L Latte, V Lauer, P Lavados, R Le Bouc, R Leal Cantu, H Lechner, K Lecouturier, S Leder, J Lee, BC Lee, A Leger, E Leira, I Leisse, R Leker, G Lembo, L Lenskaya, J Leyden, G Li, M Li, S Li, J Li, G Liamis, H Liang, Z Liang, N Ligot, H Lin, R Lindert, A Lindgren, M Linna, T Litwin, K Liu, X Liu, L Llull, B Lohninger, M Longoni, C Loomis, D Lopes, M Lopez Fernandez, N Lopez Garza, A Lord, S Louw, R Lovasz, T Lowenkopf, Z Lu, SC Lubke-Detring, R Luder, S Lujan, B Luo, L Lupinogina, G Luschin, H Lutsep, A Lvova, J Ly, G.M. Grosse, H Ma, C Ma, M Machado, C Machado, S Macher, J Machetanz, F Macian-Montoro, E Mackey, A Mackey, G Maclean, J Maestre-Moreno, A Magadan, T Magyar, A Mahagney, A Majid, A Majjhoo, K Makaritsis, J Mandzia, M Mangas Guijarro, D Mangion, E Manios, S Mann, L Manning, C Manno, J Manuel Garcia, V Maqueda, M Mar Castellanos, M Mar Freijo, C Marando, S Marcela Lepera, J Marcos Couto, G Maria Bruera, L Maria Greco, A Maria Lorenzo, S Maria Obmann, A Maria Roa, C Marini, I Marinkovic, G Mario Sumay, C Mario Torres, M Marko, S Markova, H Markus, R Marsh, E Marsili, M Marta Esnaola, J Marta Moreno, J Marti-Fabregas, S Martina Angelocola, P Martínez Sánchez, N Martinez-Majander, S Martins, O Marzelik, S Mastrocola, G Matamala, A Matoltsy, B Matosevic, S Matsumoto, A Maud, G Mauri Cabdevila, Z May, Y Mayasi, A Mayr, T Mazzoli, K Mcarthur, L Mccullough, CE Medina Pech, F Medlin, M Mehdiratta, S Mehta, D Mehta, B Mehta, M Melis, E Melnikova, B Mendez, T Mendonca, JJ Mengual Chirifie, N Menon, A Mensch, E Meseguer, S Messe, K Metcalf, N Meyer, F Michas, N Micheletti, R Mikulik, H Milionis, B Miller, T Milling, C Minelli, J Minhas, M Minns, D Mircea, S Mishra, A Mismas, A Mistri, N Mitrovic, H Miyake, B Modrau, A Moey, C Molina, J Molina, A Molis, J Moller, S Molnar, F Moniche, C Monosi, V Monzani, M Moonis, R Morais, L Morales, A Morales, D Morar-Precup, F Moreton, C Moro, E Morozova, M Morton, T Morvan, E Morvan, T Motko, A Mowla, E Mozhejko, G Muddegowda, O Mudhar, T Mueller, C Muhl, KW Muir, H Mundl, S Munoz, C Murphy, S Murphy, A Murtuzova, T Musuka, J Mutzenbach, M Myint, W Mysliwy, M Naccarato, G Naeije, Y Nagakane, I Natarajan, D Navaratnam, A Nave, B Nazliel, K Nedeltchev, J Nel, H Nell, R Nemeth, L Nemeth, O Neto, K Ng, J Ngeh, L Nicolas Chialvo, T Nieminen, M Nikkanen, J Nikl, M Nikoforova, S Nishino, Y Nishiyama, X Njovane, S Nogawa, F Nombela, B Norrving, K Nosek, B Nowak, E Nowakowska-Sledz, G Ntaios, H Numminen, F Nunez, M Obadia, S Oberndorfer, A Obrezan, J Ochiai, W Oczkowski, MJ O'Donnell, A Odyniec, K Oh, M Ohira, Y Okamoto, M Okpala, S Okubo, L Olah, V Olavarria, J Oleszek, N Onat Demirci, V Ondar, G Ongun, K Ooyama, V Orosz, R Ortiz, G Osseby, E Österlund-Tauriala, C Ovesen, S Ozcekic Demirhan, J Ozdoba-Rot, S Ozturk, E Ozyurt, M Pablo Grecco, G Pablo Povedano, M Paciaroni, C Padiglioni, J Pagola, W Palasik, G Panczel, L Panos, G Papadopoulos, E Papadopoulou, A Papagiannis, V Papavasileiou, M Papina, JR Pardo De Donlebun, V Parisi, JM Park, J Pasten, N Patel, O Pavlik, M Pawelczyk, WF Peacock, H Pei, T Peisker, LF Pena Sedna, A Penn, S Pentek, E Pepper, L Pereira, K Perera, Y Perez, S Perez, P Perez Leguizamon, M Pernicka, R Perry, A Persico, Y Pesant, S Peska, D Peters, G Peters, L Pettigrew, T Phan, S Philippi, T Phinney, F Pico, A Pidal, B Piechowski-Jozwiak, A Pieroni, S Pineiro, V Piras, N Pizova, J Polanco, M Polin, A Polyakov, E Polychronopoulou, A Polymeris, D Popov, A Poppe, P Postorino, C Pozzerese, M Pradhan, L Prats, E Prazdnichkova, B Prendl, M Pretorius, P Profice, S Prokopenko, E Pudov, V Pujol Lereis, G Punzo Bravo, F Purroy, J Qiu, X Qu, V Quenardelle, H Quesada Garcia, L Radrizzani, A Radtke, T Raffelsberger, JM Ramirez Moreno, C Ramos-Estebanez, A Rani, P Rapantova, K Rashed, A Rasheed Nihara, J Rasmussen, L Redondo Robles, M Reif, P Reiner, P Rekova, A Renu, M Repetto, P Reyes, S Reyes Morales, JH Rha, J Ribeiro, S Ricci, C Richard, R Rigual, C Rinaldi, C Riveira Rodriguez, B Rizzato, TG Robinson, A Rocco, M Rodrigues, G Rodriguez, A Rodriguez Campello, F Rodriguez Lucci, M Rodriguez Yanez, C Roesler, C Roffe, R Roine, S Roine, A Roldan, F Romana Pezzella, M Romano, JS Roos, C Rosso, C Rostrup Kruuse, Y Roth, R Roukens, L Roveri, D Rozanski, J Rozniecki, C Rozsa, S Rudilosso, G Ruiz Ares, A Ruiz Franco, G Rum, J Ruuskanen, I Rybinnik, K Ryota, J Saarinen, V Saavedra, C Sabben, A Sabet, D Sagris, J Sahlas, N Sakai, P Salamanca, P Salgado, S Salig, T Salletmayr, M Salnikov, O Samoshkina, Y Samson, D Sanak, M Sànchez Cerón, P Santalucia, M Santamaria Cadavid, P Santiago, G Santo, B Sanz Cuesta, J Sargento, A Sarraj, K Sas, A Sas, O Satoshi, S Satsoglou, N Sattar, S Savitz, C Savopoulos, J Saw, M Sawicka, R Sawyer, T Scandura, N Schillinger, J Schindler, F Schlachetzki, I Schneider, R Schuppner, J Schurig, CJ Schwarzbach, M Sebejova, G Seidel, L Sekaran, D Selcuk, J Selvarajah, A Semerano, J Semjen, D Semushina, S Sen, M Seok Park, J Serena, O Serhat Tokgoz, W Serles, F Serrano, M Sevin, L Seynaeve, S Shah, N Shamalov, T Shang, M Sharma, A Sharrief, M Shazam Hussain, I Shchukin, W Shen, E Shepeleva, I Shinsuke, A Shmonin, A Shoamanesh, A Shuaib, A Shulga, G Sibolt, I Sibon, I Sicilia, M Siebert, E Sieczkowska, C Sila, AA Silva, D Silva, P Silva, Y Silva, M Silvestrini, Z Simony, A Simpkins, B Singh, D Sinha, I Sipos, O Skoda, P Skowron, M Skowronska, B Sliwinska, J Slonkova, A Smolkin, A Smyth, P Sobolewski, A Sobota, SI Sohn, M Soldatov, I Solganov, L Soloveva, E Solovyeva, N Sonntag, P Soors, M Sorgun, C Soriano, D Spence, K Spengos, L Sposato, G Staaf, K Stadler, L Stakhovskaya, K Stamatelopoulos, S Steinert, I Stetkarova, M Stiehm, R Stocker, J Stoinski, A Stoll, G Stotts, A Stumpp, P Sucapane, T Suenaga, X Sun, S Sundararajan, J Sung Kim, H Suzuki, N Svaneborg, G Szasz, W Szczuchniak, S Szczyrba, N Szegedi, A Szekely, Z Szewczyk, G Szilagyi, S Szlufik, K Szoboszlai, L Szpisjak, R Sztajzel, L Sztriha, SE Ta Wil, J Taggeselle, K Takamatsu, M Takao, W Taki, S Takizawa, M Talahma, A Tamayo, J Tan, D Tanne, A Tapanainen, T Tapiola, J Tarasiuk, T Tatlisumak, A Tayal, S Tcvetkova, P Teal, J Tejada Garcia, H Tejada Meza, D Tenora, M Terceno, A Terentiou, S Tezcan, D Thaler, A Thomson, E Thouvenot, M Tiainen, I Timberg, S Timsit, A Tinchon, D Tirschwell, C Togay Isikay, K Tokunaga, M Tolino, C Toloza, G Tomelleri, K Tomoyuki, LM Tomppo, Z Tong, L Tong, D Toni, J Torres, C Tossavainen, G Toth, A Tountopoulou, E Touze, M Tovar, K Toyoda, S Trillo, A Trommer, D Tropepi, D Tryambake, H Tu, S Tuetuencue, R Tumova, O Tumpula, G Turc, A Tutaj, J Tynkkynen, S Uchiyama, U Uchwat, L Uhrinyakova, R Ulku Acar, D Uluduz Ugurlu, X Urra, S Urui, M Usero Ruiz, D Vaclavik, K Vahedi, A Valikovics, J Valpas, P Van Acker, W Van Daele, G Vanderschueren, L Vanina Jure, R Varela, Z Varga, J Varvat, N Varvyanskaya, A Vasco Salgado, P Vasko, L Vass, S Vassilopoulou, I Vastagh, P Vazquez, L Vecsei, R Veltkamp, M Venti, M Verdugo, V Verocai, M Veronica Marroquin, C Veronica Simonsini, T Veverka, M Vigl, A Vila, C Vilar, JA Villanueva Osorio, J Virta, E Vitkova, B Voglsperger, J Volna, PA Von Weitzel-Mudersbach, N Vora, I Voznyuk, A Wach-Klink, A Wacongne, D Walters, Y Wang, J Wang, L Wang, X Wang, W Wang, N Wang, D Wang, H Wang, W Warnack, K Wartenberg, R Waters, M Waters, T Webb, J Weber, G Weiss, K Weissenborn, JI Weitz, B Weller, G Wen, G Weng, P Werner, D Werring, P Wester, W Whiteley, R Whiting, T Wijeratne, C Willems, L Wilson, C Wilson, T Winder, J Windt, A Winkler, A Winska-Tereszkiewicz, A Wisniewska, M Wittayer, A Wlodek, A Wojnarowska-Arendt, M Wolf, V Wolff, C Wolter, A Wong, H Wook Nah, H Worthmann, W Wu, S Wu, S Wunderlich, H Wurzinger, DG Wyse, B Xiao, W Xiaopeng, A Ximenez-Carrillo, L Xiong, Y Xiong, W Xiong, Y Xu, J Xu, Z Xu, B Yalo, T Yamada, M Yamasaki, L Yang, Y Yang, X Yang, Q Yang, B Yang, J Yang, I Yasuhiro, M Yee Lam, C Yegappan, S Yip, E Ylikallio, P Ylikotila, A Yongwon Jin, BW Yoon, Y Yoshida, L Yperzeele, H Yuan, H Yuasa, J Zalewska, C Zanferrari, E Zapata, D Zboznovits, I Zelenka, C Zhang, B Zhang, S Zhang, M Zhang, X Zhang, J Zhang, L Zhao, O Zhirnova, L Zhou, J Zielinska-Turek, I Zinchenko, M Ziomek, A Zitzmann, R Zweifler, J Zwiernik

المساهمون: Yperzeele, Laetitia, NAVIGATE ESUS Investigators

المصدر: The Lancet Neurology
Andersen, G, Damgaard, D, Weitzel, P V & NAVIGATE ESUS Investigators 2018, ' Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial ', Lancet Neurology, vol. 17, no. 12, pp. 1053-1060 . https://doi.org/10.1016/S1474-4422Test(18)30319-3
Department of Medicine Publications

مصطلحات موضوعية: Male, International Cooperation, 030204 cardiovascular system & hematology, antiplatelet therapy, law.invention, Neurology (clinical), ischemic stroke, anticoagulation, Cohort Studies, 0302 clinical medicine, Randomized controlled trial, Rivaroxaban, law, Stroke, education.field_of_study, Aspirin, Anticoagulant, Settore BIO/14, Middle Aged, 3. Good health, Treatment Outcome, N/A, Cardiology, Platelet aggregation inhibitor, Settore MED/26 - Neurologia, Female, medicine.drug, medicine.medical_specialty, medicine.drug_class, MEDLINE, Population, Foramen Ovale, Patent, Subgroup analysis, Article, Statistics, Nonparametric, 03 medical and health sciences, Double-Blind Method, Internal medicine, medicine, Humans, education, Aged, business.industry, medicine.disease, Human medicine, business, 030217 neurology & neurosurgery, Platelet Aggregation Inhibitors, Factor Xa Inhibitors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cc80d72d1fd661c95636fc6998c815Test
https://pubmed.ncbi.nlm.nih.gov/30784551Test