المؤلفون: Terrett, Jack A., Ly, Justin Q., Katavolos, Paula, Hasselgren, Catrin, Laing, Steven, Zhong, Fiona, Villemure, Elisia, Déry, Martin, Larouche-Gauthier, Robin, Chen, Huifen, Shore, Daniel G., Lee, Wyne P., Suto, Eric, Johnson, Kevin, Brooks, Marjory, Stablein, Alyssa, Beaumier, Francis, Constantineau-Forget, Léa, Grand-Maître, Chantal, Lépissier, Luce, Ciblat, Stéphane, Sturino, Claudio, Chen, Yong, Hu, Baihua, Elstrott, Justin, Gandham, Vineela, Joseph, Victory, Booler, Helen, Cain, Gary, Chou, Carolina, Fullerton, Aaron, Lepherd, Michelle, Stainton, Shannon, Torres, Elizabeth, Urban, Konnie, Yu, Lanlan, Zhong, Yu, Bao, Linda, Chou, Kang-Jye, Lin, Jessica, Zhang, Wei, La, Hank, Liu, Liling, Mulder, Teresa, Chen, Jun, Chernov-Rogan, Tania, Johnson, Adam R., Hackos, David H., Leahey, Rebecca, Shields, Shannon D.

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 5, page 3287-3306 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c02121Test

المؤلفون: Dansette, Patrick, M, Sodhi, Jasleen, K, Delarosa, Marie, Halladay, Jason, S, Driscoll, James, P, Mulder, Teresa, Cyrus Khojasteh, S

المساهمون: Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Pr Vlada Urlacher

المصدر: 20th International Conference on Cytochrome P450 (ICCP 20)
https://hal.science/hal-03539866Test
20th International Conference on Cytochrome P450 (ICCP 20), Aug 2017, Dusseldorf, Germany.
https://www.biochemistry2.hhu.de/en/news/iccp450Test

مصطلحات موضوعية: ascorbate, glutathione, dimedone, indanedione: 5-methyl-1, 2-cyclohexanedione, N-ethyl-maleimide, N-methyl-maleimide, N-acetylcysteine, N-acetyllysine, morpholine, N-methylpiperidine, 2-mercatptoethanol, thiocyanate, TCEP, DTT. Ticlopidine, S-oxide, MESH: ascorbate, glutathion, indanedione: 5-methyl-1,2-cyclohexanedione, 2-mercaptoethanol, S-oxyde, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, [SDV.TOX]Life Sciences [q-bio]/Toxicology

جغرافية الموضوع: Dusseldorf, Germany

العلاقة: hal-03539866; https://hal.science/hal-03539866Test; https://hal.science/hal-03539866/documentTest; https://hal.science/hal-03539866/file/TrappingAgentP450inhibition5.ppt.pdfTest

الإتاحة: https://hal.science/hal-03539866Test
https://hal.science/hal-03539866/documentTest
https://hal.science/hal-03539866/file/TrappingAgentP450inhibition5.ppt.pdfTest

المؤلفون: Khojasteh, S Cyrus, Argikar, Upendra A, Driscoll, James P, Heck, Carley JS, King, Lloyd, Jackson, Klarissa D, Jian, Wenying, Kalgutkar, Amit S, Miller, Grover P, Kramlinger, Valerie, Rietjens, Ivonne MCM, Teitelbaum, Aaron M, Wang, Kai, Wei, Cong, Johnson, Benjamin M, Shu, Yue-Zhong, Zhuo, Xiaoliang, Meanwell, Nicholas A, Cerny, Matthew A, Obach, R Scott, Sharma, Raman, Spracklin, Douglas K, Walker, Gregory S, Goracci, Laura, Desantis, Jenny, Valeri, Aurora, Castellani, Beatrice, Eleuteri, Michela, Cruciani, Gabriele, Lall, Manjinder S, Bassyouni, Asser, Bradow, James, Brown, Maria, Bundesmann, Mark, Chen, Jinshan, Ciszewski, Gregory, Hagen, Anne E, Hyek, Dennis, Jenkinson, Stephen, Liu, Bo, Pan, Senliang, Reilly, Usa, Sach, Neal, Smaltz, Daniel J, Starr, Jeremy, Wagenaar, Melissa, de Bruyn Kops, Christina, Sicho, Martin, Mazzolari, Angelica, Kirchmair, Johannes, Korprasertthaworn, Porntipa, Chau, Nuy, Nair, Pramod C, Rowland, Andrew, Miners, John O, Wrobleski, Stephen T, Moslin, Ryan, Lin, Shuqun, Zhang, Yanlei, Spergel, Steven, Kempson, James, Tokarski, John S, Strnad, Joann, Zupa-Fernandez, Adriana, Cheng, Lihong, Shuster, David, Gillooly, Kathleen, Yang, Xiaoxia, Heimrich, Elizabeth, McIntyre, Kim W, Chaudhry, Charu, Khan, Javed, Ruzanov, Max, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Sun, Huadong, Huang, Christine, D'Arienzo, Celia, Aranibar, Nelly, Chiney, Manoj, Chimalakonda, Anjaneya, Pitts, William J, Lombardo, Louis, Carter, Percy H, Burke, James R, Weinstein, David S, Li, Jing, Liu, Ju, Enders, Jennifer, Arciprete, Michael, Tran, Chris, Aluri, Krishna, Guan, Li-Hua, O'Shea, Jonathan, Bisbe, Anna, Charisse, Klaus, Zlatev, Ivan, Najarian, Diana, Xu, Yuanxin, Kim, Jaeah, El Zahar, Noha M, Bartlett, Michael G, Katyayan, Kishore, Yi, Ping, Monk, Scott, Cassidy, Kenneth, Takahashi, Ryan H, Grandner, Jessica M, Bobba, Sudheer, Liu, Yanzhou, Beroza, Paul, Zhang, Donglu, Ma, Shuguang, Post, Noah, Yu, Rosie, Greenlee, Sarah, Gaus, Hans, Hurh, Eunju, Matson, John, Wang, Yanfeng, Tajima, Yuya, Toyoda, Takeshi, Hirayama, Yuichiro, Matsushita, Kohei, Yamada, Takanori, Ogawa, Kumiko, Watanabe, Kenji, Takamura-Enya, Takeji, Totsuka, Yukari, Wakabayashi, Keiji, Miyoshi, Noriyuki, Zhang, Jiayin, Chan, Chi-Kong, Ham, Yat-Hing, Chan, Wan, Schleiff, Mary Alexandra, Flynn, Noah R, Payakachat, Sasin, Schleiff, Benjamin Mark, Pinson, Anna O, Province, Dennis W, Swamidass, S Joshua, Boysen, Gunnar, Nardone-White, Dasean T, Bissada, Jennifer E, Abouda, Arsany A, Zhang, Zhuming, Connolly, Peter J, Lim, Heng Keang, Pande, Vineet, Meerpoel, Lieven, Teleha, Christopher, Branch, Jonathan R, Ondrus, Janine, Hickson, Ian, Bush, Tammy, Luistro, Leopoldo, Packman, Kathryn, Bischoff, James R, Ibrahim, Salam, Parrett, Christopher, Chong, Yolanda, Gottardis, Marco M, Bignan, Gilles, Mulder, Teresa, Bobba, Sudder, Johnson, Kevin M, Wang, Wei, Zhang, Chenghong, Cai, Jingwei, Choo, Edna F, Crawford, James J, Landry, Matthew L, Chen, Huifen, Kenny, Jane R, Lee, Wendy, Young, Wendy B, Geib, Timon, Thulasingam, Madhuranayaki, Haeggstrom, Jesper Z, Sleno, Lekha, Monroe, James J, Tanis, Keith Q, Podtelezhnikov, Alexei A, Nguyen, Truyen, Machotka, Sam V, Lynch, Donna, Evers, Raymond, Palamanda, Jairam, Miller, Randy R, Pippert, Todd, Cabalu, Tamara D, Johnson, Timothy E, Aslamkhan, Amy G, Kang, Wen, Tamburino, Alex M, Mitra, Kaushik, Agrawal, Nancy GB, Sistare, Frank D

المصدر: Drug Metabolism Reviews 53 (2021) 3
Drug Metabolism Reviews, 53(3), 384-433

مصطلحات موضوعية: METABOLISM, Toxicology, 030226 pharmacology & pharmacy, 03 medical and health sciences, nonp450 enzymes, 0302 clinical medicine, p450 enzymes, Biotransformation, INTRINSIC CLEARANCE, Political science, MASS-BALANCE, Humans, Pharmacology (medical), Pharmacology & Pharmacy, P450 Enzymes, General Pharmacology, Toxicology and Pharmaceutics, ANTISENSE OLIGONUCLEOTIDE, Toxicologie, VLAG, ARISTOLOCHIC ACID, Drug metabolism, Science & Technology, WIMEK, bioactivation, IDENTIFICATION, Year in review, IN-VITRO, NONHEPATOTOXIC DRUGS, Drug metabolizing enzymes, Drug development, 030220 oncology & carcinogenesis, COVALENT BINDING DATA, Engineering ethics, biotransformation, LIVER-MICROSOMES, Life Sciences & Biomedicine

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a22a3073b1b8be7c5621703d8a65f67Test
https://doi.org/10.1080/03602532.2021.1916028Test

المؤلفون: Wei Wang, Donglu Zhang, Mulder Teresa, Jingwei Cai, Susan Wong, Chenghong Zhang, Zhengyin Yan, S. Cyrus Khojasteh

المصدر: Xenobiotica. 51:15-23

مصطلحات موضوعية: Pharmacology, Wistar Han, Metabolic Clearance Rate, Health, Toxicology and Mutagenesis, Metabolite, Rat strain, General Medicine, Biology, Toxicology, Biochemistry, Rats, Rats, Sprague-Dawley, Sprague dawley, Metabolic pathway, chemistry.chemical_compound, Pharmaceutical Preparations, Pharmacokinetics, chemistry, Biotransformation, Hepatocytes, Metabolome, Animals, Drug metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c764778415f2dec17d0f706ec90bc13dTest
https://doi.org/10.1080/00498254.2020.1795949Test

المؤلفون: Yue, Qin, Khojasteh, S. Cyrus, Cho, Sungjoon, Ma, Shuguang, Mulder, Teresa, Chen, John, Pang, Jodie, Ding, Xiao, Deese, Alan, Pellet, Jackson D., Siebers, Nicholas, Joas, Lori, Salphati, Laurent, Ware, Joseph A.

المصدر: Xenobiotica ; volume 51, issue 7, page 796-810 ; ISSN 0049-8254 1366-5928

الإتاحة: https://doi.org/10.1080/00498254.2021.1923859Test

المؤلفون: Dansette, Patrick, Sodhi, Jasleen, Delarosa, Marie, Halladay, Jason, Driscoll, James, Mulder, Teresa, Cyrus Khojasteh, S

المساهمون: Dansette, Patrick

مصطلحات موضوعية: thiocyanate, [CHIM.ANAL] Chemical Sciences/Analytical chemistry, indanedione: 5-methyl-1, N-methyl-maleimide, N-acetyllysine, N-methylpiperidine, [CHIM.THER] Chemical Sciences/Medicinal Chemistry, ascorbate, S-oxide, N-acetylcysteine, 2-mercatptoethanol, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, [SDV.TOX] Life Sciences [q-bio]/Toxicology, N-ethyl-maleimide, morpholine, TCEP, DTT. Ticlopidine, glutathione, dimedone, 2-cyclohexanedione

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od_______166::465fc9e1ffb5583d9e67e16c86a79007Test
https://hal.science/hal-03539866Test

المؤلفون: Fan, Peter, Chen, Jacob, Allan Jaochico, M., La, Hank, Liu, Ning, Mulder, Teresa, Cass, Robert, Durk, Matthew, Messick, Kirsten, Valle, Nicole, Liu, Shannon, Lee, Wendy, Crawford, James, Rudolf, Joachim, Murray, Lesley, Cyrus Khojasteh, S., Wright, Matthew

المصدر: Drug Metabolism Letters ; volume 10, issue 2, page 91-100 ; ISSN 1872-3128

مصطلحات موضوعية: Pharmacology (medical), Biochemistry (medical), Clinical Biochemistry, Pharmaceutical Science

الإتاحة: https://doi.org/10.2174/1872312810666160411144358Test
http://eurekaselect.com/article/download/141160Test

المؤلفون: Mulder, Teresa, Bobba, Sudheer, Johnson, Kevin, Grandner, Jessica M., Wang, Wei, Zhang, Chenghong, Cai, Jingwei, Choo, Edna F., Khojasteh, S. Cyrus, Zhang, Donglu

المصدر: Drug Metabolism and Disposition; 2020, Vol. 48 Issue: 9 p819-829, 11p

المؤلفون: Sodhi, Jasleen K., Delarosa, Erlie Marie, Halladay, Jason S., Driscoll, James P., Mulder, Teresa, Dansette, Patrick M., Khojasteh, S. Cyrus

المصدر: International Journal of Molecular Sciences; Jul2017, Vol. 18 Issue 7, p1553, 14p, 3 Diagrams, 2 Charts

مصطلحات موضوعية: CYTOCHROME P-450, SULFUR drugs, BIOTRANSFORMATION (Metabolism), INTERMEDIATES (Chemistry), XENOBIOTICS, LIVER microsomes, NICOTINAMIDE adenine dinucleotide phosphate

المؤلفون: W. Fan, Peter, Z. Chen, Jacob, Allan Jaochico, M., La, Hank, Liu, Ning, Mulder, Teresa, T. Cass, Robert, Durk, Matthew, Messick, Kirsten, Valle, Nicole, Liu, Shannon, Lee, Wendy, J. Crawford, James, Rudolf, Joachim, J. Murray, Lesley, Cyrus Khojasteh, S., Wright, Matthew

المصدر: Drug Metabolism Letters; June 2016, Vol. 10 Issue: 2 p91-100, 10p