المؤلفون: Holt, Amy K., Najumudeen, Arafath K., Collard, Tracey J., Li, Hao, Millett, Laura M., Hoskin, Ashley J., Legge, Danny N., Mortensson, Eleanor M. H., Flanagan, Dustin J., Jones, Nicholas, Kollareddy, Madhu, Timms, Penny, Hitchings, Matthew D., Cronin, James, Sansom, Owen J., Williams, Ann C., Vincent, Emma E.

المساهمون: Institute of Biotechnology, Kidney development, Helsinki Institute of Life Science HiLIFE

مصطلحات موضوعية: Aspirin, Cb-839, Colorectal cancer, Glutaminase, Metabolic reprogramming, Metabolism, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: AKH and AJH were supported by the James Tudor Foundation; AKH, AJH and EMHM were supported by John and Bridget Maynard; and PT was supported by a PhD studentship from Bowel & Cancer Research. AKH, AJH, EMHM and PT were also supported by the John James Bristol Foundation. DF, TJC, OJS and ACW by an MRC Research Grant (MR/R017247/1). EEV and DNL are supported by Diabetes UK (17/0005587) and the World Cancer Research Fund (WCRF UK), as part of the World Cancer Research Fund International grant programme (IIG_2019_2009). EEV and TJC are supported by the Cancer Research UK (CRUK) Integrative Cancer Epidemiology Programme (C18281/A29019). AKN was supported by Cancer Research UK (CRUK) Beatson Institute core funding (A17196, A31287)-awarded to OJS. OJS was supported by CRUK grants (A21139, A12481, A17196 and A31287) and ERC Starting grant (311301). LMM is supported by a CRUK Scotland Centre Grant (CTRQQR-2021\100006).; Holt , A K , Najumudeen , A K , Collard , T J , Li , H , Millett , L M , Hoskin , A J , Legge , D N , Mortensson , E M H , Flanagan , D J , Jones , N , Kollareddy , M , Timms , P , Hitchings , M D , Cronin , J , Sansom , O J , Williams , A C & Vincent , E E 2023 , ' Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition ' , Cancer & Metabolism , vol. 11 , 18 . https://doi.org/10.1186/s40170-023-00318-yTest; 79183b88-6bce-46f8-be9f-33f80fb83f77; http://hdl.handle.net/10138/568723Test; 001097431700001

الإتاحة: http://hdl.handle.net/10138/568723Test

المؤلفون: Holt, Amy K, Collard, Tracey J, Hoskin, Ashley J, Legge, Danny N, Mortensson, Eleanor M H, Kollareddy, Madhu, Timms, Penny, Williams, Ann C, Vincent, Emma E

المصدر: Holt , A K , Collard , T J , Hoskin , A J , Legge , D N , Mortensson , E M H , Kollareddy , M , Timms , P , Williams , A C & Vincent , E E 2023 , ' Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition ' , BMC Cancer & Metabolism . https://doi.org/10.1186/s40170-023-00318-yTest

مصطلحات موضوعية: /dk/atira/pure/core/keywords/icep, ICEP

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الإتاحة: https://doi.org/10.1186/s40170-023-00318-yTest
https://hdl.handle.net/1983/74d8743d-36df-4cd8-a509-12b4a7ab44ecTest
https://research-information.bris.ac.uk/en/publications/74d8743d-36df-4cd8-a509-12b4a7ab44ecTest
https://research-information.bris.ac.uk/ws/files/387028531/Holt_et_al_Aspirin_revised_clean.docxTest

المؤلفون: Dixon, Steven W, Collard, Tracey J, Mortensson, Eleanor M H, Legge, Danny N, Chambers, Adam Christian, Greenhough, Alexander, Creed, Tom J, Williams, Ann C

المصدر: Dixon , S W , Collard , T J , Mortensson , E M H , Legge , D N , Chambers , A C , Greenhough , A , Creed , T J & Williams , A C 2021 , ' 5-aminosalicylic acid inhibits stem cell function in human adenoma derived cells : implications for chemoprophylaxis in colorectal tumorigenesis ' , British Journal of Cancer , vol. 124 , no. 12 , pp. 1959-1969 . https://doi.org/10.1038/s41416-021-01354-5Test

مصطلحات موضوعية: 5-aminosalicylic acid (5-ASA), colorectal cancer, β-catenin, LGR5

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41416-021-01354-5Test
https://hdl.handle.net/1983/a87cd8da-f67e-4195-befb-e0528e04ded0Test
https://research-information.bris.ac.uk/en/publications/a87cd8da-f67e-4195-befb-e0528e04ded0Test
https://research-information.bris.ac.uk/ws/files/283320261/s41416_021_01354_5.pdfTest