المؤلفون: Sally H Cross, Danilo G Macalinao, Lisa McKie, Lorraine Rose, Alison L Kearney, Joe Rainger, Caroline Thaung, Margaret Keighren, Shalini Jadeja, Katrine West, Stephen C Kneeland, Richard S Smith, Gareth R Howell, Fiona Young, Morag Robertson, Rob van T' Hof, Simon W M John, Ian J Jackson

المصدر: PLoS Genetics, Vol 10, Iss 5, p e1004359 (2014)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC4014447?pdf=renderTest; https://doaj.org/toc/1553-7390Test; https://doaj.org/toc/1553-7404Test

الوصول الحر: https://doaj.org/article/dc810faba09b405ebb5e4373b5094526Test

المؤلفون: Colin Gordon, Anna Sznajder, Jane A. Endicott, Bethan Medina, Morag Robertson, Jonas Boehringer, Konstantinos Paraskevopoulos

المصدر: The Journal of Biological Chemistry
Medina, B, Paraskevopoulos, K, Boehringer, J, Sznajder, A, Robertson, M, Endicott, J & Gordon, C 2012, ' The ubiquitin-associated (UBA) 1 domain of Schizosaccharomyces pombe Rhp23 is essential for the recognition of ubiquitin-proteasome system substrates both in vitro and in vivo ', Journal of Biological Chemistry, vol. 287, no. 50, pp. 42344-51 . https://doi.org/10.1074/jbc.M112.419838Test

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Protein domain, Biophysics, Protein degradation, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Protein Degradation, Schizosaccharomyces, Molecular Biology, 030304 developmental biology, 0303 health sciences, Cell-Free System, Proteasome, biology, Cell Biology, biology.organism_classification, Fusion protein, Yeast Genetics, Protein Structure, Tertiary, Ubiquitin ligase, DNA-Binding Proteins, 030220 oncology & carcinogenesis, Schizosaccharomyces pombe, biology.protein, Schizosaccharomyces pombe Proteins, Molecular Biophysics, Protein Binding, Binding domain

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75dd8ab5b6ebe46769e8b7f4b54a55dcTest
https://doi.org/10.1074/jbc.m112.419838Test

المؤلفون: Violetta Karwacki-Neisius, David A. Kelly, Nicola Festuccia, Douglas Colby, Pablo Navarro, Wensheng Zhang, Rodrigo Osorno, Morag Robertson, Alessia Gagliardi, Nicholas P. Mullin, Ian Chambers

المصدر: The EMBO Journal. 31:4547-4562

مصطلحات موضوعية: Regulation of gene expression, Genetics, Homeobox protein NANOG, 0303 health sciences, General Immunology and Microbiology, General Neuroscience, Rex1, Cellular differentiation, fungi, Gene regulatory network, Nanog Homeobox Protein, Biology, General Biochemistry, Genetics and Molecular Biology, Cell biology, 03 medical and health sciences, 0302 clinical medicine, SOX2, embryonic structures, biological phenomena, cell phenomena, and immunity, Induced pluripotent stem cell, Molecular Biology, reproductive and urinary physiology, 030217 neurology & neurosurgery, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::565f3e76fc7c75808817a26bf92a3942Test
https://doi.org/10.1038/emboj.2012.321Test

المؤلفون: Shalini Jadeja, Lisa McKie, Robert E MacLaren, Jacqueline K. White, Ian J. Jackson, Sally H. Cross, Morag Robertson, Peter S. Budd, Alun R. Barnard

المصدر: Jadeja, S, Barnard, A R, McKie, L, Cross, S H, Sanger Mouse Genetics Project, S M G P, Robertson, M, Budd, P S, MacLaren, R E & Jackson, I J 2015, ' Mouse Slc9a8 mutants exhibit retinal defects due to retinal pigmented epithelium dysfunction ', Investigative Ophthalmology & Visual Science (IOVS), vol. 56, no. 5 . https://doi.org/10.1167/iovs.14-15735Test

مصطلحات موضوعية: Sodium-Hydrogen Exchangers, genetic structures, Mutant, Cell Culture Techniques, Fluorescent Antibody Technique, Retinal Pigment Epithelium, Biology, Real-Time Polymerase Chain Reaction, chemistry.chemical_compound, Gene Knockout Techniques, Mice, Retinal Diseases, medicine, Genetics, Electroretinography, Animals, Gene Silencing, Intraocular Pressure, Retina, Retinal pigment epithelium, Microscopy, Confocal, Reabsorption, Retinal, eye diseases, Cell biology, Mice, Inbred C57BL, Ophthalmoscopy, Disease Models, Animal, medicine.anatomical_structure, chemistry, Biochemistry, Knockout mouse, Mutation, sense organs, Cotransporter, Plasmids

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63fad5ae53b3273d43e4ad8ad063961Test
https://europepmc.org/articles/PMC4538965Test/

المؤلفون: Douglas Colby, Frances H. Stenhouse, Jennifer Nichols, Jamie R. K. Marland, Ian Chambers, Susan Tweedie, Morag Robertson

المصدر: Mammalian Genome. 17:732-743

مصطلحات موضوعية: Homeobox protein NANOG, Retroelements, Molecular Sequence Data, Retrotransposon, Biology, Mice, Open Reading Frames, Genetics, Animals, Amino Acid Sequence, Gene, reproductive and urinary physiology, Progenitor, Homeodomain Proteins, Genome, Stem Cells, Point mutation, Nanog Homeobox Protein, Embryonic stem cell, Human genetics, DNA-Binding Proteins, Open reading frame, embryonic structures, biological phenomena, cell phenomena, and immunity, Sequence Alignment

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb861193069a9f9486037caa4abaed7Test
https://doi.org/10.1007/s00335-005-0131-yTest

المؤلفون: Matt Brown, Anthony Li, Morag Robertson, Karl Smart, Georgina Smyth, Heather Yeomans

المصدر: Drug Discovery Today. 8:963-966

مصطلحات موضوعية: Pharmacology, Drug Discovery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::063e927a3a6124104ebf78060e9df909Test
https://doi.org/10.1016/s1359-6446Test(03)02871-x

المؤلفون: Vicky Ashton, Matt Brown, Joanne Clough, Morag Robertson, Sheema Sheikh

المصدر: Drug Discovery Today. 7:1027-1030

مصطلحات موضوعية: Pharmacology, Drug Discovery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c627601e6ff7333679c14b237344ccf4Test
https://doi.org/10.1016/s1359-6446Test(02)02477-7

المؤلفون: Shalini Jadeja, Margaret A. Keighren, Richard S. Smith, Sally H. Cross, Rob van't Hof, Katrine West, Ian J. Jackson, Alison L. Kearney, Danilo G. Macalinao, Gareth R. Howell, Joe Rainger, Simon W. M. John, Morag Robertson, Stephen C. Kneeland, Lisa McKie, Caroline Thaung, Lorraine Rose, Fiona Young

المصدر: Cross, S H, Macalinao, D G, McKie, L, Rose, L, Kearney, A L, Rainger, J, Thaung, C, Keighren, M, Jadeja, S, West, K, Kneeland, S C, Smith, R S, Howell, G R, Young, F, Robertson, M, van t' Hof, R, John, S W M & Jackson, I J 2014, ' A Dominant-Negative Mutation of Mouse Lmx1b Causes Glaucoma and Is Semi-lethal via LBD1-Mediated Dimerisation ', PLoS Genetics, vol. 10, no. 5, e1004359 . https://doi.org/10.1371/journal.pgen.1004359Test
PLOS GENETICS

مصطلحات موضوعية: Genetics, Genetically modified mouse, Cancer Research, Mutation, Heterozygote advantage, Dominant-Negative Mutation, Biology, medicine.disease_cause, Null allele, medicine, Missense mutation, Allele, Haploinsufficiency, Molecular Biology, Genetics (clinical), Ecology, Evolution, Behavior and Systematics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487b33befe5e723a486cf1eea8ee358eTest
https://hdl.handle.net/20.500.11820/6cc59846-1ba7-4024-8c9d-1d6678e890a0Test

المؤلفون: Sally H, Cross, Danilo G, Macalinao, Lisa, McKie, Lorraine, Rose, Alison L, Kearney, Joe, Rainger, Caroline, Thaung, Margaret, Keighren, Shalini, Jadeja, Katrine, West, Stephen C, Kneeland, Richard S, Smith, Gareth R, Howell, Fiona, Young, Morag, Robertson, Rob, van T' Hof, Simon W M, John, Ian J, Jackson

المصدر: PLoS Genetics

مصطلحات موضوعية: Heterozygote, Genetic Screens, Organogenesis, LIM-Homeodomain Proteins, Mutation, Missense, Limb Development, Gene Identification and Analysis, Mice, Transgenic, Research and Analysis Methods, Mice, Model Organisms, Molecular Cell Biology, Morphogenesis, Genetics, Animals, Alleles, Body Patterning, Genes, Dominant, Biology and Life Sciences, Glaucoma, Cell Biology, Mutagenesis, Genetics of Disease, Mutation, Genes, Lethal, Gene Function, Dimerization, Organism Development, Animal Genetics, Transcription Factors, Research Article, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::09d9ea778f2271e46040a476402514ccTest
https://pubmed.ncbi.nlm.nih.gov/24809698Test

المؤلفون: Morag Robertson, Chris Cook, Tom Harrison, Jane Willey

المصدر: Psychiatric Bulletin. 30:385-387

مصطلحات موضوعية: Psychotherapist, Point (typography), media_common.quotation_subject, Work related stress, 030227 psychiatry, 03 medical and health sciences, Psychiatry and Mental health, 0302 clinical medicine, Stress (linguistics), Wife, 030212 general & internal medicine, Psychology, Social psychology, media_common

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::dbc69274a7003dbc82143854fc64bcbfTest
https://doi.org/10.1192/pb.30.10.385Test