المؤلفون: Spanov, Baubek, Baartmans, Bas, Olaleye, Oladapo, Nicolardi, Simone, Govorukhina, Natalia, Wuhrer, Manfred, van de Merbel, Nico C, Bischoff, Rainer

المصدر: Spanov , B , Baartmans , B , Olaleye , O , Nicolardi , S , Govorukhina , N , Wuhrer , M , van de Merbel , N C & Bischoff , R 2023 , ' Revealing charge heterogeneity of stressed trastuzumab at the subunit level ' , Analytical and Bioanalytical Chemistry , vol. 415 , no. 8 , pp. 1505-1513 . https://doi.org/10.1007/s00216-023-04547-4Test

مصطلحات موضوعية: Trastuzumab, Antibodies, Monoclonal/chemistry, Chromatography, Liquid, Papain, Tandem Mass Spectrometry

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/85dd931a-0029-4c18-b779-53e78afd3229Test

الإتاحة: https://doi.org/10.1007/s00216-023-04547-4Test
https://hdl.handle.net/11370/85dd931a-0029-4c18-b779-53e78afd3229Test
https://research.rug.nl/en/publications/85dd931a-0029-4c18-b779-53e78afd3229Test
https://pure.rug.nl/ws/files/847077777/s00216-023-04547-4.pdfTest

المؤلفون: Fedechkin, Stanislav O, George, Natasha L, Wolff, Jacob T, Kauvar, Lawrence M, DuBois, Rebecca M

المصدر: Science immunology. 3(21)

مصطلحات موضوعية: Antibodies, Monoclonal: chemistry, Antibodies, Neutralizing: chemistry, Antigens, Viral: chemistry, immunology, CX3C Chemokine Receptor 1: immunology, Cell Line, Tumor, Chemokine CX3CL1: immunology, Humans, Protein Conformation, Respiratory Syncytial Virus, Human: immunology, Viral Fusion Proteins: chemistry, immunology

الوصول الحر: https://escholarship.org/uc/item/9q9938scTest

المؤلفون: Fongaro, Benedetta, Cian, Valentina, Gabaldo, Francesca, De Paoli, Giorgia, Miolo, Giorgia, Polverino de Laureto, Patrizia

المصدر: European Journal of Pharmaceutics and Biopharmaceutics, 176, 54-74 (2022-07)

مصطلحات موضوعية: Artificial sunlight, Dilution effect, Mechanical stability, Monoclonal antibody, Photostability, Protein drug product, Antibodies, Monoclonal, Antineoplastic Agents, Immunological, Excipients, Ipilimumab, Antibodies, Monoclonal/chemistry, Antibodies, Monoclonal/pharmacology, Excipients/chemistry, Humans, Protein Stability, Drug Stability, Biotechnology, Pharmaceutical Science, General Medicine, Life sciences, Biochemistry, biophysics & molecular biology, Human health sciences, Immunology & infectious disease, Sciences du vivant, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Immunologie & maladie infectieuse

العلاقة: info:eu-repo/grantAgreement/EC/H2020/101007939; https://api.elsevier.com/content/article/PII:S0939641122000935?httpAccept=text/xmlTest; urn:issn:0939-6411; urn:issn:1873-3441

الوصول الحر: https://orbi.uliege.be/handle/2268/295247Test

المؤلفون: van Lith, Sanne A M, Huizing, Fokko J, Franssen, Gerben M, Hoeben, Bianca A W, Lok, Jasper, Doulkeridou, Sofia, Boerman, Otto C, Gotthardt, Martin, van Bergen En Henegouwen, Paul M P, Bussink, Johan, Heskamp, Sandra

المساهمون: MS Radiotherapie, Cancer

مصطلحات موضوعية: Albumins/metabolism, Animals, Antibodies, Monoclonal/chemistry, Antigens, Neoplasm/metabolism, Carbonic Anhydrase IX/metabolism, Cell Line, Tumor, Half-Life, Head and Neck Neoplasms/diagnostic imaging, Humans, Hypoxia, Mice, Pentetic Acid, Tissue Distribution, Tomography, Emission-Computed, Single-Photon, carbonic anhydrase IX (CAIX), variable domain of heavy chain only antibody (VHH), tumor hypoxia, albumin-binding domain (ABD), Drug Discovery, Molecular Medicine, Pharmaceutical Science, Journal Article

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/447666Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/447666Test

المؤلفون: Bluemel, Oliver, Buecheler, Jakob W., Hauptmann, Astrid, Hoelzl, Georg, Bechtold-Peters, Karoline, Wolfgang

المصدر: http://lobid.org/resources/99370672103606441Test#!, 38(11):1977-1989.

مصطلحات موضوعية: Buffers [MeSH], Scale-down device, Concentration gradient, Monoclonal antibody, Freeze–thaw, Large-scale thawing, Excipients/chemistry [MeSH], Research Paper, Excipients/analysis [MeSH], Polysorbates/chemistry [MeSH], Antibodies, Monoclonal/chemistry [MeSH], Chemistry, Pharmaceutical [MeSH], Polysorbates/analysis [MeSH], Drug Storage [MeSH], Freezing [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6444827Test; https://doi.org/10.1007/s11095-021-03117-6Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688388Test/

الإتاحة: https://doi.org/10.1007/s11095-021-03117-6Test
https://repository.publisso.de/resource/frl:6444827Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688388Test/

المساهمون: Hyoun-Ah Kim, Eunyoung Lee, Sun-Kyung Lee, Yong-Beom Park, Kichul Shin, Park, Yong Beom

مصطلحات موضوعية: Antibodies, Monoclonal / chemistry, Monoclonal / pharmacology, Antirheumatic Agents* / therapeutic use, Biosimilar Pharmaceuticals* / adverse effects, Humans, Infliximab / adverse effects, Infliximab / chemistry, Propensity Score, Registries, Republic of Korea, Rheumatology, Spondylitis, Ankylosing* / drug therapy, Treatment Outcome

العلاقة: BIODRUGS; J04063; OAK-2021-02545; https://ir.ymlib.yonsei.ac.kr/handle/22282913/183886Test; T202007202; BIODRUGS, Vol.34(4) : 529-539, 2020-08

الإتاحة: https://doi.org/10.1007/s40259-020-00432-zTest
https://ir.ymlib.yonsei.ac.kr/handle/22282913/183886Test

المساهمون: Kyeonghye Guk, Hyeran Kim, Miyeon Lee, Yoon-Aa Choi, Seul Gee Hwang, Gaon Han, Hye-Nan Kim, Hongki Kim, Hwangseo Park, Dongeun Yong, Taejoon Kang, Eun-Kyung Lim, Juyeon Jung, Yong, Dong Eun

مصطلحات موضوعية: Amino Acid Sequence, Animals, Antibodies, Monoclonal / chemistry, Monoclonal / immunology, Viral / chemistry, Viral / immunology, Antibody Affinity / immunology, Antigens, Viral / metabolism, Body Fluids / virology, DNA Mutational Analysis, Dogs, Drug Resistance, Multiple / immunology, Epitopes / chemistry, Epitopes / immunology, Humans, Influenza A Virus, H1N1 Subtype / enzymology, H1N1 Subtype / immunology, H3N2 Subtype / enzymology, H3N2 Subtype / immunology, Madin Darby Canine Kidney Cells, Molecular Docking Simulation, Mutation / genetics, Neuraminidase / genetics, Optical Imaging, Protein Binding, Spectrum Analysis

وصف الملف: application/pdf

العلاقة: NATURE COMMUNICATIONS; J02293; OAK-2021-05622; https://ir.ymlib.yonsei.ac.kr/handle/22282913/184920Test; T999202131; NATURE COMMUNICATIONS, Vol.11(1) : 3418, 2020-07

الإتاحة: https://doi.org/10.1038/s41467-020-17246-wTest
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184920Test

المؤلفون: Tamberg, Trine, Hong, Zebin, De Schepper, Daphné, Skovbjerg, Signe, Dupont, Daniel M, Vitved, Lars, Schar, Christine R, Skjoedt, Karsten, Vogel, Lotte K, Jensen, Jan K

المصدر: Tamberg , T , Hong , Z , De Schepper , D , Skovbjerg , S , Dupont , D M , Vitved , L , Schar , C R , Skjoedt , K , Vogel , L K & Jensen , J K 2019 , ' Blocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors ' , Journal of Biological Chemistry , vol. 294 , no. 1 , pp. 314-326 . https://doi.org/10.1074/jbc.RA118.004126Test

مصطلحات موضوعية: CLEAVAGE, COMPLEX, CRYSTAL-STRUCTURE, EPITHELIAL DEVELOPMENT, FACTOR ACTIVATOR INHIBITOR-1, HEPATOCYTE GROWTH-FACTOR, PLASMINOGEN-ACTIVATOR, POTENT, PROTEASE MATRIPTASE, SURVIVAL, TTSP, cancer therapy, enzyme inhibitor, enzyme kinetics, epitope mapping, matriptase, multi-domain protein, serine protease, surface plasmon resonance (SPR), zymogen, Humans, Antibodies, Monoclonal/chemistry, Crystallography, X-Ray, Enzyme Precursors/antagonists & inhibitors, Proteolysis, HEK293 Cells, Protein Domains, Protease Inhibitors/chemistry

العلاقة: https://pure.au.dk/portal/en/publications/7028f3d9-db4b-4a12-b5a1-efa17401af7aTest

الإتاحة: https://doi.org/10.1074/jbc.RA118.004126Test
https://pure.au.dk/portal/en/publications/7028f3d9-db4b-4a12-b5a1-efa17401af7aTest
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322904/pdf/zbc314.pdfTest

المؤلفون: Romero Pastrana, Francisco, Thompson, John M., Heuker, Marjolein, Hoekstra, Hedzer, Dillen, Carly A., Ortines, Roger V., Ashbaugh, Alyssa G., Pickett, Julie E., Linssen, Matthijs D., Bernthal, Nicholas M., Francis, Kevin P., Buist, Girbe, van Oosten, Marleen, van Dam, Gooitzen M., Thorek, Daniel L. J., Miller, Lloyd S., van Dijl, Jan Maarten

المصدر: Romero Pastrana , F , Thompson , J M , Heuker , M , Hoekstra , H , Dillen , C A , Ortines , R V , Ashbaugh , A G , Pickett , J E , Linssen , M D , Bernthal , N M , Francis , K P , Buist , G , van Oosten , M , van Dam , G M , Thorek , D L J , Miller , L S & van Dijl , J M 2018 , ' Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal ....

مصطلحات موضوعية: Animals, Antibodies, Monoclonal/chemistry, Antigens, Bacterial/metabolism, Cadaver, Disease Models, Animal, Fluorescent Dyes/chemistry, Humans, Mice, Optical Imaging/methods, Staphylococcal Infections/diagnostic imaging, Staphylococcal Skin Infections/diagnostic imaging, Staphylococcus aureus/isolation & purification

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/a4ff441f-6cdb-412d-8eac-d2c186a54c0dTest

الإتاحة: https://doi.org/10.1080/21505594.2017.1403004Test
https://hdl.handle.net/11370/a4ff441f-6cdb-412d-8eac-d2c186a54c0dTest
https://research.rug.nl/en/publications/a4ff441f-6cdb-412d-8eac-d2c186a54c0dTest
https://pure.rug.nl/ws/files/56872377/4_16_2018_Noninvasiv.pdfTest

المؤلفون: Fan, Ying, Howden, Andrew J. M., Sarhan, Adil R., Lis, Pawel, Ito, Genta, Martinez, Terina N., Brockmann, Kathrin, Gasser, Thomas, Alessi, Dario R., Sammler, Esther

المصدر: Fan , Y , Howden , A J M , Sarhan , A R , Lis , P , Ito , G , Martinez , T N , Brockmann , K , Gasser , T , Alessi , D R & Sammler , E 2018 , ' Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils ' , Biochemical Journal , vol. 475 , no. 1 , pp. 23-44 . https://doi.org/10.1042/BCJ20170803Test

مصطلحات موضوعية: Animals, Antibodies, Monoclonal/chemistry, Phospho-Specific/chemistry, Antibody Specificity, Case-Control Studies, Clinical Trials as Topic, Enzyme Assays, Epitopes/chemistry, Gene Expression Regulation, Genetic Predisposition to Disease, Gyrus Cinguli/immunology, Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/antagonists & inhibitors, Leukocytes, Mononuclear/immunology, Mutation, Neutrophils/immunology, Parkinson Disease/enzymology, Phosphorylation, Protein Kinase Inhibitors/pharmacology, Rabbits, Signal Transduction, rab GTP-Binding Proteins/chemistry

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/ec90e688-b79c-41b9-b36c-ed2a72462bfdTest

الإتاحة: https://doi.org/10.1042/BCJ20170803Test
https://discovery.dundee.ac.uk/en/publications/ec90e688-b79c-41b9-b36c-ed2a72462bfdTest
https://discovery.dundee.ac.uk/ws/files/19932393/23.full.pdfTest
http://www.scopus.com/inward/record.url?scp=85046120944&partnerID=8YFLogxKTest